专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

91. 发明申请

US20100324620A1 PERCUTANEOUS NEUROSTIMULATOR FOR MODULATING CARDIOVASCULAR FUNCTION 有权
标题翻译：用于调节心脏功能的PERCUTANEOUS神经调节器
公开(公告)号：US20100324620A1
公开(公告)日：2010-12-23
申请号：US12869579
申请日：2010-08-26
申请人： Imad Libbus , Anthony V. Caparso , Andrew P. Kramer
发明人： Imad Libbus , Anthony V. Caparso , Andrew P. Kramer
IPC分类号： A61N1/36
CPC分类号： A61N1/05 , A61N1/36014 , A61N1/36017 , A61N1/36114 , A61N1/365 , A61N1/37211 , A61N1/37252 , A61N1/37288
摘要： A neurostimulation device includes an external neurostimulator worn by a patient using a bracing element that braces a portion of the patient's body. The external neurostimulator delivers neurostimulation to modulate a cardiovascular function of the patient. In one embodiment, the external stimulator delivers neurostimulation percutaneously to a stimulation target in the patient's body using at least one percutaneous stimulation electrode having a distal end lodged on or near the stimulation target.
摘要翻译：神经刺激装置包括由患者佩戴的外部神经刺激器，其使用支撑患者身体的一部分的支撑元件。外部神经刺激仪提供神经刺激来调节患者的心血管功能。在一个实施例中，外部刺激器使用至少一个经皮刺激电极将刺激神经刺激经皮刺激到患者体内的刺激目标，所述经皮刺激电极具有放置在刺激靶上或附近的远端。

92. 发明申请

US20100298898A1 BAROREFLEX ACTIVATION FOR ARRHYTHMIA TREATMENT 审中-公开
标题翻译： BAROREFLEX激活ARRHYTHMIA治疗
公开(公告)号：US20100298898A1
公开(公告)日：2010-11-25
申请号：US12850245
申请日：2010-08-04
申请人： Imad Libbus
发明人： Imad Libbus
IPC分类号： A61N1/365 , A61N1/36 , A61N1/39
CPC分类号： A61N1/36117 , A61N1/36139 , A61N1/3627 , A61N1/36564
摘要： An aspect of the present subject matter relates to a system for providing baroreflex stimulation. An embodiment of the system comprises an adverse event detector to sense an adverse event and provide a signal indicative of the adverse event, and a baroreflex stimulator. The stimulator includes a pulse generator to provide a baroreflex stimulation signal adapted to provide a baroreflex therapy, and a modulator to receive the signal indicative of the adverse event and modulate the baroreflex stimulation signal based on the signal indicative of the adverse event to change the baroreflex therapy from a first baroreflex therapy to a second baroreflex therapy. Other aspects are provided herein.
摘要翻译：本主题的一个方面涉及一种用于提供压力反射刺激的系统。系统的实施例包括用于感测不利事件并提供指示不利事件的信号的不利事件检测器和压力反射激励器。刺激器包括脉冲发生器以提供适于提供压力反射治疗的压力反射刺激信号，以及调制器，用于接收指示不利事件的信号，并且基于指示不利事件的信号来调节压力反射刺激信号以改变压力反射从第一次压力反射治疗到第二次压力反射治疗。本文提供了其他方面。

93. 发明授权

US07761151B2 Intermittent high-energy cardiac stimulation for therapeutic effect 有权
标题翻译：间歇性高能心脏刺激治疗效果
公开(公告)号：US07761151B2
公开(公告)日：2010-07-20
申请号：US11466679
申请日：2006-08-23
申请人： Joseph M. Pastore , Imad Libbus , Andrew P. Kramer , Julio C. Spinelli
发明人： Joseph M. Pastore , Imad Libbus , Andrew P. Kramer , Julio C. Spinelli
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61N1/3622
摘要： A device and method for delivering high-energy electrical stimulation to the heart in order to improve cardiac function in heart failure patients. The high-energy stimulation mimics the effects of exercise and improves symptoms even in patients who are exercise intolerant. The high-energy stimulation may be delivered on an intermittent basis either as pacing pulses in accordance with a programmed pacing mode and with a higher pacing pulse energy than used for conventional pacing or as low energy shock pulses.
摘要翻译：用于向心脏递送高能电刺激以改善心力衰竭患者的心脏功能的装置和方法。高能量刺激模拟运动的影响，即使在运动不耐受的患者中也能改善症状。高能量刺激可以间歇地作为起搏脉冲递送，或者作为起搏脉冲根据编程的起搏模式和较高的起搏脉冲能量而不是用于常规起搏或低能量冲击脉冲。

94. 发明授权

US07747323B2 Adaptive baroreflex stimulation therapy for disordered breathing 有权
标题翻译：适应性压力反射刺激治疗无序呼吸
公开(公告)号：US07747323B2
公开(公告)日：2010-06-29
申请号：US10863826
申请日：2004-06-08
申请人： Imad Libbus , Quan Ni , Kent Lee
发明人： Imad Libbus , Quan Ni , Kent Lee
IPC分类号： A61N1/365
CPC分类号： A61N1/3611 , A61N1/3601 , A61N1/36135
摘要： An approach to providing disordered breathing therapy includes delivering electrical stimulation therapy modifying a patient's baroreflex response. Disordered breathing therapy may be delivered in response to prediction or detection of disordered breathing events. Various conditions affecting the patient may be evaluated and the baroreflex therapy modified. The therapy may be modified to improve therapy efficacy, to reduce an impact to the patient and/or to mitigate therapy interactions.
摘要翻译：提供无序呼吸治疗的方法包括传递改变患者压力反射反应的电刺激疗法。无序呼吸治疗可以响应于预测或检测到无序呼吸事件而被传送。可以评估影响患者的各种状况，并修改压力反射治疗。可以修改治疗以改善治疗功效，减少对患者的影响和/或减轻治疗相互作用。

95. 发明授权

US07643875B2 Baroreflex stimulation system to reduce hypertension 有权
标题翻译： Baroreflex刺激系统可以降低高血压
公开(公告)号：US07643875B2
公开(公告)日：2010-01-05
申请号：US10746134
申请日：2003-12-24
申请人： Ronald W. Heil, Jr. , Avram Scheiner , Imad Libbus
发明人： Ronald W. Heil, Jr. , Avram Scheiner , Imad Libbus
IPC分类号： A61N1/36
CPC分类号： A61N1/36117 , A61N1/3627 , A61N1/36564
摘要： Various aspects of the present subject matter provide an implantable medical device. In various embodiments, the device comprises a pulse generator, a lead, a sensor, and a controller. The pulse generator generates a baroreflex stimulation signal as part of a baroreflex therapy. The lead is adapted to be electrically connected to the pulse generator and to be intravascularly fed into a heart. The lead includes an electrode to be positioned in or proximate to the heart to deliver the baroreflex signal to a baroreceptor region in or proximate to the heart. The sensor senses a physiological parameter regarding an efficacy of the baroreflex therapy and provides a signal indicative of the efficacy. The controller is connected to the pulse generator to control the baroreflex stimulation signal and to the sensor to receive the signal indicative of the efficacy of the baroreflex therapy. Other aspects are provided herein.
摘要翻译：本主题的各个方面提供可植入医疗装置。在各种实施例中，装置包括脉冲发生器，引线，传感器和控制器。脉冲发生器产生压力反射刺激信号作为压力反射治疗的一部分。引线适于电连接到脉冲发生器并且被血管内馈送到心脏中。引线包括位于心脏中或靠近心脏的电极，以将压力反射信号传递到心脏中或心脏附近的压力感受器区域。传感器感测关于压力反射治疗的功效的生理参数，并提供指示功效的信号。控制器连接到脉冲发生器以控制压力反射刺激信号和传感器以接收指示压力反射治疗功效的信号。本文提供了其他方面。

96. 发明授权

US07630760B2 Neural stimulation therapy system for atherosclerotic plaques 失效
标题翻译：动脉粥样硬化斑块神经刺激治疗系统
公开(公告)号：US07630760B2
公开(公告)日：2009-12-08
申请号：US11284370
申请日：2005-11-21
申请人： Imad Libbus , Julio C. Spinelli , Tamara Colette Baynham
发明人： Imad Libbus , Julio C. Spinelli , Tamara Colette Baynham
IPC分类号： A61N1/32
CPC分类号： A61N1/056 , A61N1/0556 , A61N1/36014 , A61N1/36114 , A61N1/36135 , A61N1/362
摘要： A neural stimulation therapy system for atherosclerotic plaques is provided. One aspect of this disclosure relates to a medical device for applying neural stimulation therapy for atherosclerotic plaques. The device includes a neural stimulator adapted to deliver an electrical signal through at least one electrode to an autonomic neural target. The device also includes a controller to control the neural stimulator to provide a therapy for atherosclerotic plaques. The device is external to a human body in an embodiment, and includes an implantable medical device (IMD) in various embodiments. According to an embodiment, the device includes a neural stimulation lead connected to the neural stimulator. The neural stimulator delivers electrical signals with waveform parameters based on sensed arterial blockage levels, according to various embodiments. Other aspects and embodiments are provided herein.
摘要翻译：提供了一种用于动脉粥样硬化斑块的神经刺激治疗系统。本公开的一个方面涉及用于对动脉粥样硬化斑块施加神经刺激疗法的医疗装置。该装置包括适于将电信号通过至少一个电极输送到自主神经靶的神经刺激器。该装置还包括控制器以控制神经刺激器以提供动脉粥样硬化斑块的治疗。在一个实施例中，该装置在人体外部，并且在各种实施例中包括可植入医疗装置（IMD）。根据实施例，该装置包括连接到神经刺激器的神经刺激引线。根据各种实施例，神经刺激器基于感测的动脉阻塞水平递送具有波形参数的电信号。本文提供了其它方面和实施例。

97. 发明授权

US07596413B2 Coordinated therapy for disordered breathing including baroreflex modulation 有权
标题翻译：协调治疗无序呼吸，包括压力反射调制
公开(公告)号：US07596413B2
公开(公告)日：2009-09-29
申请号：US10863827
申请日：2004-06-08
申请人： Imad Libbus , Quan Ni , Kent Lee
发明人： Imad Libbus , Quan Ni , Kent Lee
IPC分类号： A61N1/08 , F16K31/02
CPC分类号： A61N1/3601 , A61N1/36114 , A61N1/36117
摘要： An approach to providing disordered breathing therapy involves the use of a plurality of therapy devices to deliver a coordinated disordered breathing therapy regimen to the patient. The plurality of disordered breathing devices includes at least a therapy device that delivers an electrical stimulation therapy modulating a patient's baroreflex response. Other therapy devices may include a cardiac electrical stimulation device, an external respiratory therapy device, and/or other therapy devices used in the treatment of disordered breathing. A therapy controller coordinates the therapies delivered by the plurality of therapy devices.
摘要翻译：提供无序呼吸治疗的方法包括使用多个治疗装置将协调的无序呼吸治疗方案递送给患者。多个无序呼吸装置至少包括一种治疗装置，其传递调节患者的压力反射响应的电刺激治疗。其他治疗装置可以包括心脏电刺激装置，外部呼吸治疗装置和/或用于治疗无序呼吸的其它治疗装置。治疗控制器协调由多个治疗装置递送的治疗。

98. 发明授权

US07555341B2 System to treat AV-conducted ventricular tachyarrhythmia 有权
标题翻译：系统治疗AV进行性室性快速性心律失常
公开(公告)号：US07555341B2
公开(公告)日：2009-06-30
申请号：US11099226
申请日：2005-04-05
申请人： Julia Moffitt , Andrew P. Kramer , Imad Libbus
发明人： Julia Moffitt , Andrew P. Kramer , Imad Libbus
IPC分类号： A61N1/08
CPC分类号： A61N1/36114 , A61B5/0464 , A61N1/0587 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/3962 , A61N2001/0585
摘要： Various aspects of the present subject matter provide devices and methods to treat AV-conducted ventricular tachyarrhythmia (AVCVT). According to various embodiments of the method, an AVCVT is sensed, an IVC-LA fat pad is stimulated when the AVCVT is sensed to block AV conduction, and bradycardia support pacing is provided while the IVC-LA fat pad is stimulated. Other aspects and embodiments are provided herein.
摘要翻译：本主题的各个方面提供了治疗AV进行性室性快速性心律失常（AVCVT）的装置和方法。根据该方法的各种实施例，感测到AVCVT，当检测到AVCVT以阻止AV传导时刺激IVC-LA脂肪垫，并且在IVC-LA脂肪垫被刺激的同时提供心动过缓支持起搏。本文提供了其它方面和实施例。

99. 发明授权

US07548780B2 Cell therapy and neural stimulation for cardiac repair 失效
标题翻译：细胞治疗和神经刺激用于心脏修复
公开(公告)号：US07548780B2
公开(公告)日：2009-06-16
申请号：US11063170
申请日：2005-02-22
申请人： Imad Libbus , Jeffrey Ross , Steven D. Girouard
发明人： Imad Libbus , Jeffrey Ross , Steven D. Girouard
IPC分类号： A61N1/18
CPC分类号： A61N1/36114 , A61K41/00 , A61N1/362
摘要： A method and system to enhance cell, gene and/or cytokine therapy for cardiac repair in a mammal.
摘要翻译：用于增强哺乳动物心脏修复的细胞，基因和/或细胞因子治疗的方法和系统。

100. 发明授权

US07509166B2 Automatic baroreflex modulation responsive to adverse event 有权
标题翻译：响应于不良事件的自动压力反射调制
公开(公告)号：US07509166B2
公开(公告)日：2009-03-24
申请号：US10745925
申请日：2003-12-24
申请人： Imad Libbus
发明人： Imad Libbus
IPC分类号： A61N1/362
CPC分类号： A61N1/36117 , A61N1/36139 , A61N1/3627 , A61N1/36564
摘要： An aspect of the present subject matter relates to a system for providing baroreflex stimulation. An embodiment of the system comprises an adverse event detector to sense an adverse event and provide a signal indicative of the adverse event, and a baroreflex stimulator. The stimulator includes a pulse generator to provide a baroreflex stimulation signal adapted to provide a baroreflex therapy, and a modulator to receive the signal indicative of the adverse event and modulate the baroreflex stimulation signal based on the signal indicative of the adverse event to change the baroreflex therapy from a first baroreflex therapy to a second baroreflex therapy. Other aspects are provided herein.
摘要翻译：本主题的一个方面涉及一种用于提供压力反射刺激的系统。系统的实施例包括用于感测不利事件并提供指示不利事件的信号的不利事件检测器和压力反射激励器。刺激器包括脉冲发生器以提供适于提供压力反射治疗的压力反射刺激信号，以及调制器，用于接收指示不利事件的信号，并且基于指示不利事件的信号来调节压力反射刺激信号以改变压力反射从第一次压力反射治疗到第二次压力反射治疗。本文提供了其他方面。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式