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91. 发明授权

US07807445B2 Antibiotic compound 有权
标题翻译：抗生素
公开(公告)号：US07807445B2
公开(公告)日：2010-10-05
申请号：US11587074
申请日：2005-05-20
申请人： Angela Basilio , Olga Genilloud , Hiranthi Jayasuriya , Ignacio Gonzalez , Sheo B. Singh , Oscar Salazar , Jun Wang
发明人： Angela Basilio , Olga Genilloud , Hiranthi Jayasuriya , Ignacio Gonzalez , Sheo B. Singh , Oscar Salazar , Jun Wang
IPC分类号： A61K39/10 , A61K31/195 , C07C229/00
CPC分类号： C07C235/78 , A61K31/609 , C07C2603/70 , C12P13/02
摘要： Fermentation of a nutrient medium with a eubacterium Streptomyces sp. yields a novel antibacterial compound of structural formula (I).
摘要翻译：用链霉菌（Streptomyces sp。）发酵营养培养基得到结构式（I）的新型抗菌化合物。

92. 发明申请

US20100228016A1 DNA comprising a DNA SEQ. of isolated glucose isomerase 有权
标题翻译： DNA包含DNA SEQ。的葡萄糖异构酶
公开(公告)号：US20100228016A1
公开(公告)日：2010-09-09
申请号：US12723918
申请日：2010-03-15
申请人： Jun Wang , Caike Jin , Rongzhao Fu , Dong Shen
发明人： Jun Wang , Caike Jin , Rongzhao Fu , Dong Shen
IPC分类号： C07H21/04
CPC分类号： C12N9/92 , C12P19/24
摘要： This invention provides a series of recombinant Thermoanaerobacterium saccharolyticum glucose isomerases with improved catalytic activity and thermostability obtained by using recombinant techniques. These recombinant glucose isomerases comprise amino acid variation including phenylalanine (Phe) at position 139, alanine (Ala) at position 182, serine (Ser) at position 187, and glutamine (Gln) at position 299, and carry at least one additional mutated amino acid at position 87, position 217, position 260 or position 276, and possess a higher catalytic activity than that of the wild-type when using D-glucose as substrate. These recombinant glucose isomerases can be used for direct production of high fructose corn syrup containing 55% [wt] or higher concentration of fructose.
摘要翻译：本发明提供了一系列通过使用重组技术获得的具有改进的催化活性和热稳定性的重组热酵母杆菌葡萄糖异构酶。这些重组葡萄糖异构酶包括氨基酸变异，包括139位的苯丙氨酸（Phe），182位的丙氨酸（Ala），187位的丝氨酸（Ser）和299位的谷氨酰胺（Gln），并携带至少一种另外的突变氨基在第87位，217位，260位或276位具有较高的酸性，当使用D-葡萄糖作为底物时，其具有比野生型更高的催化活性。这些重组葡萄糖异构酶可用于直接生产含有55％（重量）或更高浓度果糖的高果糖玉米糖浆。

93. 发明申请

US20100227365A1 Methods of using isolated glucose isomerase 有权
标题翻译：使用分离的葡萄糖异构酶的方法
公开(公告)号：US20100227365A1
公开(公告)日：2010-09-09
申请号：US12723833
申请日：2010-03-15
申请人： Jun Wang , Caike Jin , Rongzhao Fu , Dong Shen
发明人： Jun Wang , Caike Jin , Rongzhao Fu , Dong Shen
IPC分类号： C12P19/24
CPC分类号： C12N9/92 , C12P19/24
摘要： This invention provides a series of recombinant Thermoanaerobacterium saccharolyticum glucose isomerases with improved catalytic activity and thermostability obtained by using recombinant techniques. These recombinant glucose isomerases comprise amino acid variation including phenylalanine (Phe) at position 139, alanine (Ala) at position 182, serine (Ser) at position 187, and glutamine (Gin) at position 299, and carry at least one additional mutated amino acid at position 87, position 217, position 260 or position 276, and possess a higher catalytic activity than that of the wild-type when using D-glucose as substrate. These recombinant glucose isomerases can be used for direct production of high fructose corn syrup containing 55% [wt] or higher concentration of fructose.
摘要翻译：本发明提供了一系列通过使用重组技术获得的具有改进的催化活性和热稳定性的重组热酵母杆菌葡萄糖异构酶。这些重组葡萄糖异构酶包括氨基酸变异，包括139位的苯丙氨酸（Phe），182位的丙氨酸（Ala），187位的丝氨酸（Ser）和299位的谷氨酰胺（Gin），并携带至少一种其它的突变氨基在第87位，217位，260位或276位具有较高的酸性，当使用D-葡萄糖作为底物时，其具有比野生型更高的催化活性。这些重组葡萄糖异构酶可用于直接生产含有55％（重量）或更高浓度果糖的高果糖玉米糖浆。

94. 发明申请

US20100221769A1 ELECTROPORATIVE FLOW CYTOMETRY 审中-公开
标题翻译：电子流量计
公开(公告)号：US20100221769A1
公开(公告)日：2010-09-02
申请号：US12716974
申请日：2010-03-03
申请人： Chang LU , Jun Wang , Ning Bao , Robert L. Geahlen
发明人： Chang LU , Jun Wang , Ning Bao , Robert L. Geahlen
IPC分类号： C12Q1/02 , C12M1/34
CPC分类号： G01N33/5005 , G01N15/147 , G01N15/1484 , G01N33/574
摘要： Novel devices and methods are provided, which include electroporative flow cytometry, where electroporation is combined with flow cytometry. The devices and methods can be used for the detection a variety of cellular features, including protein translocation, and for monitoring biomechanics at single cell level. Using the novel devices methods it is possible to observe the release of proteins such as intracellular kinases out of the cells during electroporation. Using the novel devices methods it is possible to study cytoskeleton dynamics and deformability at a single cell level, and to correlate these to diseases such as cancers.
摘要翻译：提供了新的装置和方法，其中包括电穿孔流式细胞术，其中电穿孔与流式细胞术结合。该装置和方法可用于检测各种细胞特征，包括蛋白质易位，以及用于监测单细胞水平的生物力学。使用新颖的器件方法，可以观察电穿孔期间蛋白质如细胞内激酶的释放。使用新颖的器件方法，可以在单细胞水平上研究细胞骨架动力学和变形能力，并将其与诸如癌症的疾病相关联。

95. 发明授权

US07778631B2 Synchronization of stored service parameters in a communication system 有权
标题翻译：存储的服务参数在通信系统中的同步
公开(公告)号：US07778631B2
公开(公告)日：2010-08-17
申请号：US11046442
申请日：2005-01-28
申请人： Sai Yiu Duncan Ho , Edward G. Tiedemann, Jr. , Jun Wang , Ragulan Sinnarajah , Ramin Rezaiifar
发明人： Sai Yiu Duncan Ho , Edward G. Tiedemann, Jr. , Jun Wang , Ragulan Sinnarajah , Ramin Rezaiifar
IPC分类号： H04M3/00
CPC分类号： H04L69/24 , H04L67/04 , H04L67/1095 , H04L67/303 , H04W8/22 , H04W8/24 , H04W48/14 , H04W76/11 , H04W76/18 , H04W76/19 , H04W76/20
摘要： Techniques for synchronization of stored service parameters are disclosed. In one aspect, a configuration identifier is transmitted from a mobile station to a base station, and compared with an identifier generated in the base station. If the identifiers match, the configuration is used for communication. In another aspect, the identifier is generated by selecting an identifier associated with a configuration from a configuration table. In yet another aspect, the identifier is generated by computing a cyclic redundancy check (CRC) of the configuration. Various other aspects are also presented. These aspects have the benefit of preventing attempted use of unsynchronized stored service parameters and associated call setup failures and subsequent renegotiation, with the net effect of reducing call setup time and more efficient use of system resources.
摘要翻译：公开了存储的服务参数的同步技术。一方面，从移动台向基站发送配置标识符，并与基站中生成的标识符进行比较。如果标识符匹配，则配置用于通信。在另一方面，通过从配置表中选择与配置相关联的标识符来生成标识符。在另一方面，通过计算配置的循环冗余校验（CRC）来生成标识符。还提出了各种其他方面。这些方面具有防止尝试使用不同步存储的服务参数和相关联的呼叫建立失败以及随后的重新协商的优点，具有减少呼叫建立时间和更有效地利用系统资源的净效果。

96. 发明申请

US20100185772A1 METHOD FOR IMPLEMENTING SERVICE INTERACTION IN THE IP MULTIMEDIA SUBSYSTEM 有权
标题翻译：在IP多媒体子系统中实现服务交互的方法
公开(公告)号：US20100185772A1
公开(公告)日：2010-07-22
申请号：US12665679
申请日：2007-12-29
申请人： Jun Wang , Zhenwu Hao
发明人： Jun Wang , Zhenwu Hao
IPC分类号： G06F15/16
CPC分类号： H04L65/1016 , H04L65/1006 , H04L65/1063 , H04L65/1069 , H04L67/14 , H04L67/146 , H04L67/16
摘要： A method for implementing service interaction in the IP multimedia subsystem is disclosed in the present invention, wherein each service logic has a unique service identifier. The method comprises the following steps: (a) a Serving-Call Session Control Function (S-CSCF) sends a session initiation protocol (SIP) request message to the service capability interaction manager (SCIM) or to the application server (AS) to which a user requests for a service; (b) after the AS or SCIM has received the request and has executed this service, it inserts the service identifier of this service into the SIP request, and returns the SIP request with the service identifier to said S-CSCF. With the present invention, most of the service interaction requirements can be satisfied.
摘要翻译：在本发明中公开了一种用于实现IP多媒体子系统中的服务交互的方法，其中每个服务逻辑具有唯一的服务标识符。该方法包括以下步骤：（a）服务呼叫会话控制功能（S-CSCF）将会话发起协议（SIP）请求消息发送到服务能力交互管理器（SCIM）或应用服务器（AS）到用户请求一个服务; （b）在AS或SCIM收到请求并已执行该业务之后，将该业务的业务标识符插入到SIP请求中，并将具有业务标识符的SIP请求返回给所述S-CSCF。利用本发明，可以满足大部分的服务交互需求。

97. 发明授权

US07751821B2 Method and apparatus to initiate point-to-point call during shared-channel delivery of broadcast content in a wireless telephone network 有权
标题翻译：在无线电话网络中的广播内容的共享信道传送期间发起点对点呼叫的方法和装置
公开(公告)号：US07751821B2
公开(公告)日：2010-07-06
申请号：US12331270
申请日：2008-12-09
申请人： Ragulan Sinnarajah , Jun Wang , Tao Chen
发明人： Ragulan Sinnarajah , Jun Wang , Tao Chen
IPC分类号： H04Q7/20
CPC分类号： H04W76/20 , H04W4/06 , H04W4/16 , H04W68/00 , H04W76/23 , H04W76/40
摘要： A method for managing a point-to-point call initiated (702) between a wireless mobile station (114, 400) and a remote party while the mobile is receiving broadcast content via one or more multi-user forward-link broadcast channels (508). The mobile station notifies (704) the network (110) of preferences as to prescribed categories of operating conditions, such as whether to continue receiving the broadcast content, and election between the point-to-point call and the broadcast content should network resources be unable to conduct the point-to-point call and broadcast content concurrently. In accordance with the preferences, communications are conducted (706) in one of the following operating modes: (1) conducting the point-to-point call and discontinuing reception of the broadcast, (2) conducting the point-to-point call and continuing reception of the broadcast, (3) aborting completion of the point-to-point call and continuing reception of the broadcast.
摘要翻译：一种用于在移动台经由一个或多个多用户前向链路广播信道（508）接收广播内容时管理在无线移动站（114,400）和远程方之间发起的点对点呼叫（702）的方法）。移动台向网络（110）通知关于规定类别的操作条件（例如是否继续接收广播内容）以及网络资源之间的点对点呼叫和广播内容之间的选择的偏好无法同时进行点对点呼叫和广播内容。根据偏好，通过以下操作模式之一进行通信（706）：（1）进行点对点呼叫和停止广播的接收，（2）进行点对点呼叫和继续接收广播，（3）中止点对点呼叫的完成和继续接收广播。

98. 发明授权

US07750036B2 Carvedilol salts, corresponding compositions, methods of delivery and/or treatment 有权
标题翻译：卡维地洛盐，相应的组合物，递送和/或治疗方法
公开(公告)号：US07750036B2
公开(公告)日：2010-07-06
申请号：US10997230
申请日：2004-11-24
申请人： Christopher S. Brook , Pingyun Y. Chen , Wei Chen , Qunying Dai , Philip C. Dell'Orco , Clifford S. Labaw , Ann Marie Diederich , Choon K. Oh , Claire Hisler , David H. Igo , Lee M. Katrincic , Li-Jen Ping , Paul G. Spoors , Jun Wang , Christopher Werner
发明人： Christopher S. Brook , Pingyun Y. Chen , Wei Chen , Qunying Dai , Philip C. Dell'Orco , Clifford S. Labaw , Ann Marie Diederich , Choon K. Oh , Claire Hisler , David H. Igo , Lee M. Katrincic , Li-Jen Ping , Paul G. Spoors , Jun Wang , Christopher Werner
IPC分类号： A61K31/403 , C07D209/82
CPC分类号： C07D209/88
摘要： The present invention relates to a salt of carvedilol and/or corresponding solvates thereof, compositions containing such carvedilol and/or corresponding solvates thereof, and/or methods of using the aforementioned compound(s) in the treatment of certain disease states in mammals, in particular man.The present invention further relates to carvedilol phosphate salts, and/or solvates thereof, which include a novel crystalline form of carvedilol dihydrogen phosphate (i.e., which is the dihydrogen phosphate salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol) and/or carvedilol hydrogen phosphate, etc.) and/or other corresponding solvates thereof, compositions containing these carvedilol phosphate salts and/or solvates, and methods of using the aforementioned salts and/or solvates to treat hypertension, congestive heart failure and angina, etc.
摘要翻译：本发明涉及卡维地洛和/或其相应溶剂合物的盐，含有这种卡维地洛和/或其相应溶剂化物的组合物和/或使用上述化合物治疗哺乳动物某些疾病状态的方法，特别的人本发明还涉及卡维地洛磷酸盐和/或其溶剂合物，其包括新颖的卡维地洛磷酸二氢盐结晶形式（即它是1-（咔唑-4-基氧基-3 - [[2 - （邻甲氧基苯氧基）乙基]氨基] -2-丙醇）和/或卡维地洛磷酸氢盐等）和/或其它相应的溶剂合物，含有这些卡维地洛磷酸盐和/或溶剂化物的组合物，以及使用上述盐和/或溶剂化物治疗高血压，充血性心力衰竭和心绞痛等

99. 发明申请

US20100166492A1 SECURITY PIN AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：安全引脚及其制造方法
公开(公告)号：US20100166492A1
公开(公告)日：2010-07-01
申请号：US12436264
申请日：2009-05-06
申请人： Jun Wang
发明人： Jun Wang
IPC分类号： F16P7/00 , F16D9/06 , B23P17/00
CPC分类号： F16P7/00 , F16B5/00 , F16B31/00 , F16D9/08 , Y10T29/49988 , Y10T403/11
摘要： A security pin includes a first sleeve, a second sleeve and a core. An end surface of the first sleeve contacts with an end surface of the second sleeve, and the core is positioned in the first sleeve and the second sleeve. The breakpoint of security pin is determined by the material and the size of the core. The core is not easily broken when applied by an external force. The security pin also has a relatively precise breakpoint.
摘要翻译：安全销包括第一套筒，第二套筒和芯子。第一套筒的端面与第二套筒的端面接触，并且芯部位于第一套筒和第二套筒中。安全针的断点由芯的材料和尺寸决定。当外力施加时，内芯不容易断裂。安全引脚也具有相对精确的断点。

100. 发明授权

US07738083B2 Distant measurement method and distant measurement system 有权
标题翻译：远程测量方法和远距离测量系统
公开(公告)号：US07738083B2
公开(公告)日：2010-06-15
申请号：US12025817
申请日：2008-02-05
申请人： Yin-Long Luo , Song Li , Jun Wang
发明人： Yin-Long Luo , Song Li , Jun Wang
IPC分类号： G01C3/08
CPC分类号： G01S17/325
摘要： A distant measurement method and a distant measurement system are provided. The distant measurement method includes the following steps: emitting a first light beam and a second light beam from an emitting terminal, wherein the first light beam travels toward a target; providing a switching sequence by a switch mechanism; placing a receiving terminal to receive the first light beam reflected from the target in accordance with the switching sequence and correspondingly provide a first electrical signal, and to receive the second light beam and correspondingly provide a second electrical signal; and utilizing a controlling terminal to receive the first and second electrical signals, and calculate distance between the distant measurement system and the target in accordance with a phase differential formed between the first and second electrical signals.
摘要翻译：提供远程测量方法和远程测量系统。远距离测量方法包括以下步骤：从发射端发射第一光束和第二光束，其中第一光束朝向目标传播; 通过开关机构提供切换序列; 放置接收终端根据切换顺序接收从目标物反射的第一光束，并相应地提供第一电信号，并接收第二光束并相应地提供第二电信号; 以及利用控制终端接收第一和第二电信号，并且根据形成在第一和第二电信号之间的相位差来计算远距离测量系统与目标之间的距离。

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