专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

91. 发明授权

US09175295B2 Modified transposon vector and its use 有权
标题翻译：改性转座子载体及其用途
公开(公告)号：US09175295B2
公开(公告)日：2015-11-03
申请号：US11994982
申请日：2006-07-04
申请人： Kazuyoshi Kaminaka , Hiroaki Maeda , Masaki Hirashima , Ryoichi Kawamura , Junichi Matsuda , Takashi Kuwana
发明人： Kazuyoshi Kaminaka , Hiroaki Maeda , Masaki Hirashima , Ryoichi Kawamura , Junichi Matsuda , Takashi Kuwana
IPC分类号： C12N15/79 , C12N5/10 , C12N15/85
CPC分类号： C12N15/79 , A01K2217/05 , A01K2227/30 , C12N15/102 , C12N15/85 , C12N15/90 , C12N2800/30 , C12N2800/90 , C12N2820/00
摘要： A modified transposon vector and a method for introducing a foreign gene into a cell are provided. A modified transposon vector wherein a nucleic acid fragment having the following features (a)-(b) or (a)-(c) is inserted; a cell expressing a foreign gene obtained by introducing said vector into chromosomal DNA of a cell line or an ontogenetic cell and further introducing an expression cassette of a foreign gene into the chromosomal DNA; a genetically recombined animal generated by using said cell (in case of an ontogenetic cell); and a method for producing a foreign protein from said cell and said genetically recombined animal: (a) It consists of 5′- and 3′-TIR sequences of a transposon gene; (b) A sequence where a recombination reaction occurs is inserted between at least either of DR regions present by twos each in 5′- and 3′-TIR sequences of a transposon gene; (c) A restriction enzyme recognition site or an expression cassette of a foreign gene is inserted between 5′- and 3′-TIR sequences of a transposon gene.
摘要翻译：提供了修饰的转座子载体和将外源基因导入细胞的方法。其中插入具有以下特征（a） - （b）或（a） - （c）的核酸片段的修饰的转座子载体; 通过将所述载体导入细胞系或本体细胞的染色体DNA而获得的表达外源基因的细胞，并进一步将外源基因的表达盒导入染色体DNA; 通过使用所述细胞产生的遗传重组的动物（在个体发生细胞的情况下）; 以及从所述细胞和所述遗传重组动物产生外源蛋白的方法：（a）其由转座子基因的5'和3'-TIR序列组成; （b）将重组反应发生的序列插入转座子基因的5'-和3-TIR序列中的两个存在的至少任一个DR区域; （c）将外来基因的限制性内切酶识别位点或表达盒插入转座子基因的5'和3'-TIR序列之间。

92. 发明申请

US20150047066A1 PLANT HAVING INCREASED RESISTANCE OR SUSCEPTIBILITY TO 4-HPPD INHIBITOR 审中-公开
标题翻译：具有4-HPPD抑制剂的耐腐蚀性或耐腐蚀性的植物
公开(公告)号：US20150047066A1
公开(公告)日：2015-02-12
申请号：US13976526
申请日：2011-12-26
申请人： Hiroshi Kato , Hideo Maeda , Yoshihiro Sunohara , Ikuo Ando , Masahiro Oshima , Motoshige Kawata , Hitoshi Yoshida , Sakiko Hirose , Makiko Kawagishi , Yojiro Taniguchi , Kazumasa Murata , Hiroaki Maeda , Yuji Yamada , Keisuke Sekino , Akihiko Yamazaki
发明人： Hiroshi Kato , Hideo Maeda , Yoshihiro Sunohara , Ikuo Ando , Masahiro Oshima , Motoshige Kawata , Hitoshi Yoshida , Sakiko Hirose , Makiko Kawagishi , Yojiro Taniguchi , Kazumasa Murata , Hiroaki Maeda , Yuji Yamada , Keisuke Sekino , Akihiko Yamazaki
IPC分类号： C12N15/82 , C12Q1/68
CPC分类号： C12N15/8274 , C12N9/0004 , C12Q1/6895
摘要： By a QTL analysis and so forth using 4-HPPD inhibitor-susceptible rice and 4-HPPD inhibitor-resistant rice, a hypothetical gene (HIS1 gene) of an iron/ascorbate-dependent oxidoreductase gene located on a short arm of chromosome 2 of rice has been identified as a 4-HPPD inhibitor-resistance gene. Further, it has also been revealed that a homologous gene (HSL1 gene) of the HIS1 gene is located on chromosome 6 of rice. Furthermore, it has been found out that utilizations of these genes make it possible to efficiently produce a plant having increased resistance or susceptibility to a 4-HPPD inhibitor and to efficiently determine whether a plant has resistance or susceptibility to a 4-HPPD inhibitor.
摘要翻译：通过使用4-HPPD抑制剂敏感水稻和4-HPPD抑制剂抗性水稻的QTL分析等，位于水稻2号染色体短臂上的铁/抗坏血酸依赖性氧化还原酶基因的假设基因（HIS1基因）已被鉴定为4-HPPD抑制剂抗性基因。此外，还揭示了HIS1基因的同源基因（HSL1基因）位于水稻的6号染色体上。此外，已经发现，这些基因的利用使得有可能有效地生产对4-HPPD抑制剂具有增加的抗性或易感性的植物，并有效地确定植物是否具有对4-HPPD抑制剂的抗性或易感性。

93. 发明授权

US08618978B2 Position information providing system indoor transmitter and method for providing position information 有权
标题翻译：位置信息提供系统室内发射机和提供位置信息的方法
公开(公告)号：US08618978B2
公开(公告)日：2013-12-31
申请号：US12745478
申请日：2008-11-27
申请人： Hideyuki Torimoto , Makoto Ishii , Masahiro Asako , Dinesh Manandhar , Satoshi Kogure , Tomoyuki Miyano , Motohisa Kishimoto , Hiroaki Maeda
发明人： Hideyuki Torimoto , Makoto Ishii , Masahiro Asako , Dinesh Manandhar , Satoshi Kogure , Tomoyuki Miyano , Motohisa Kishimoto , Hiroaki Maeda
IPC分类号： G01S19/48
CPC分类号： G01S19/11 , H04W64/003
摘要： Provided is a position information providing system which can reduce a time required for acquiring position information. An indoor transmitter is adapted to provide position information by using a second positioning signal compatible with a first positioning signal which is a spread spectrum signal from each of a plurality of satellites. The indoor transmitter includes an EEPROM which stores therein position data for identifying an installation location thereof, an FPGA operable to generate a second positioning signal including the position data as a spread spectrum signal, and a transmitting section operable to transmit the spread spectrum signal. The second positioning signal is generated to repeat the same content in a cycle shorter than that of the first positioning signal.
摘要翻译：提供一种位置信息提供系统，其可以减少获取位置信息所需的时间。室内发射器适于通过使用与作为来自多个卫星中的每一个的扩频信号的第一定位信号兼容的第二定位信号来提供位置信息。室内发送机包括EEPROM，其中存储有用于识别其安装位置的位置数据;可操作地生成包括作为扩展频谱信号的位置数据的第二定位信号的FPGA和可用于发送扩频信号的发送部分。生成第二定位信号，以比第一定位信号短的周期重复相同的内容。

94. 发明授权

US08558616B2 Amplifying apparatus 有权
标题翻译：放大装置
公开(公告)号：US08558616B2
公开(公告)日：2013-10-15
申请号：US13234285
申请日：2011-09-16
申请人： Yoshinobu Shizawa , Hiroaki Maeda , Yousuke Okazaki , Hirotake Honda
发明人： Yoshinobu Shizawa , Hiroaki Maeda , Yousuke Okazaki , Hirotake Honda
IPC分类号： H03F1/26 , H03G3/20 , H03F1/32
CPC分类号： H03F1/3247 , H03F3/24 , H03F2200/102 , H03F2201/3224 , H03F2201/3233
摘要： An amplifying apparatus includes a first amplifier that amplifies an input signal on the basis of a value of a drain voltage and outputs a transmission signal, a distortion compensator that corrects a power amplitude of the input signal on the basis of a difference in power amplitude between the input signal and the transmission signal outputted from the first amplifier, a drain voltage controller that generates the drain voltage on the basis of the power amplitude of the input signal to be corrected, and a drain voltage corrector that corrects the drain voltage on the basis of the difference.
摘要翻译：放大装置包括：第一放大器，其基于漏极电压的值放大输入信号，并输出发送信号;失真补偿器，其基于功率幅度的差异来校正输入信号的功率幅度; 从第一放大器输出的输入信号和发送信号，基于要校正的输入信号的功率振幅来产生漏极电压的漏极电压控制器，以及基于漏极电压校正基准的漏极电压校正器的区别。

95. 发明授权

US08406660B2 Image forming apparatus including counter-rotating developing rollers and controlling method 有权
标题翻译：图像形成装置，包括反转显影辊和控制方法
公开(公告)号：US08406660B2
公开(公告)日：2013-03-26
申请号：US12700064
申请日：2010-02-04
申请人： Tomonari Hokkyoh , Hiroaki Maeda , Katsuhiro Akinaga , Koutarou Yamada
发明人： Tomonari Hokkyoh , Hiroaki Maeda , Katsuhiro Akinaga , Koutarou Yamada
IPC分类号： G03G15/08
CPC分类号： G03G15/09 , G03G15/5008
摘要： The disclosed image forming apparatus includes a rotatable image holding body configured to hold an electrostatic latent image on a surface of the image holding body, a developing device including a forward rotation developing roller rotatable in a same rotational direction as that of the rotatable image holding body and a reverse rotation developing roller rotatable in a reverse rotational direction to that of the rotatable image holding body, which supply a two-component developer to the surface of the image holding body to form a toner image corresponding to the electrostatic latent image, and a control unit configured to control rotation of the image holding body, the forward rotation developing roller, and the reverse rotation developing roller to supply the two-component developer. The control unit controls the rotation of the image holding body to start after a predetermined time period from starting the rotation of the forward rotation developing roller and the reverse rotation developing roller.
摘要翻译：所公开的图像形成装置包括：可旋转图像保持体，其构造成将静电潜像保持在图像保持体的表面上;显影装置，包括可旋转的旋转图像保持体的旋转方向的正转显影辊以及反转显影辊，其以与可旋转图像保持体相反的旋转方向旋转，将双组分显影剂供应到图像保持体的表面，以形成与静电潜像对应的调色剂图像;以及控制单元，被配置为控制图像保持体，正向旋转显影辊和反转显影辊的旋转，以供应双组分显影剂。控制单元控制图像保持体的旋转，以在从正向旋转显影辊和反转显影辊的旋转开始的预定时间段之后开始。

96. 发明申请

US20110183911A1 METHOD FOR IMPROVING NEUROTRANSMISSION FAILURE USING A NOVEL AGENT 审中-公开
标题翻译：使用新型药剂改善神经递质失败的方法
公开(公告)号：US20110183911A1
公开(公告)日：2011-07-28
申请号：US13012545
申请日：2011-01-24
申请人： Ryoichi Kawamura , Takeshi Naruse , Masaki Hirashima , Kazuyoshi Kaminaka , Junichi Matsuda , Hiroaki Maeda , Mami Noda , Keiji Wada
发明人： Ryoichi Kawamura , Takeshi Naruse , Masaki Hirashima , Kazuyoshi Kaminaka , Junichi Matsuda , Hiroaki Maeda , Mami Noda , Keiji Wada
IPC分类号： A61K38/17 , C07K14/435 , A61P25/00
CPC分类号： A61K38/1709
摘要： A novel medicament for ameliorating neurotransmission dysfunction diseases is provided. A medicament for ameliorating neurotransmission dysfunction diseases comprising as a main active ingredient preferably a selenocysteine-containing protein such as Selenoprotein P or a selenocysteine-containing peptide that consists of said protein or a series of said peptides. A medicament suited for ameliorating neurotransmission dysfunction diseases caused by various pathological conditions is provided.
摘要翻译：提供了用于改善神经传递功能障碍疾病的新型药物。一种用于改善神经传递功能障碍疾病的药物，其包含主要活性成分，优选含有硒代半胱氨酸的蛋白质如硒蛋白P或含有所述蛋白质或一系列所述肽的含硒代胱氨酸的肽。提供了适用于改善由各种病理状况引起的神经传递功能障碍疾病的药物。

97. 发明申请

US20100281551A1 MODIFIED TRANSPOSON VECTOR AND ITS USE 有权
标题翻译：改进的传输矢量及其使用
公开(公告)号：US20100281551A1
公开(公告)日：2010-11-04
申请号：US11994982
申请日：2006-07-04
申请人： Kazuyoshi Kaminaka , Hiroaki Maeda , Masaki Hirashima , Ryoichi Kawamura , Junichi Matsuda , Takashi Kuwana
发明人： Kazuyoshi Kaminaka , Hiroaki Maeda , Masaki Hirashima , Ryoichi Kawamura , Junichi Matsuda , Takashi Kuwana
IPC分类号： A01K67/033 , C12N15/79 , C12P21/00 , C12N5/10
CPC分类号： C12N15/79 , A01K2217/05 , A01K2227/30 , C12N15/102 , C12N15/85 , C12N15/90 , C12N2800/30 , C12N2800/90 , C12N2820/00
摘要： A modified transposon vector and a method for introducing a foreign gene into a cell are provided. A modified transposon vector wherein a nucleic acid fragment having the following features (a)-(b) or (a)-(c) is inserted; a cell expressing a foreign gene obtained by introducing said vector into chromosomal DNA of a cell line or an ontogenetic cell and further introducing an expression cassette of a foreign gene into the chromosomal DNA; a genetically recombined animal generated by using said cell (in case of an ontogenetic cell); and a method for producing a foreign protein from said cell and said genetically recombined animal: (a) It consists of 5′- and 3′-TIR sequences of a transposon gene; (b) A sequence where a recombination reaction occurs is inserted between at least either of DR regions present by twos each in 5′- and 3′-TIR sequences of a transposon gene; (c) A restriction enzyme recognition site or an expression cassette of a foreign gene is inserted between 5′- and 3′-TIR sequences of a transposon gene.
摘要翻译：提供了修饰的转座子载体和将外源基因导入细胞的方法。其中插入具有以下特征（a） - （b）或（a） - （c）的核酸片段的修饰的转座子载体; 通过将所述载体导入细胞系或本体细胞的染色体DNA而获得的表达外源基因的细胞，并进一步将外源基因的表达盒导入染色体DNA; 通过使用所述细胞产生的遗传重组的动物（在个体发生细胞的情况下）; 以及从所述细胞和所述遗传重组动物产生外源蛋白的方法：（a）其由转座子基因的5'和3'-TIR序列组成; （b）将重组反应发生的序列插入转座子基因的5'-和3-TIR序列中的两个存在的至少任一个DR区域; （c）将外来基因的限制性内切酶识别位点或表达盒插入转座子基因的5'和3'-TIR序列之间。

98. 发明授权

US07575872B2 Antibody against von Willebrand factor cleaving enzyme and assay system using the same 有权
标题翻译：抗von Willebrand因子切割酶的抗体和使用其的测定系统
公开(公告)号：US07575872B2
公开(公告)日：2009-08-18
申请号：US10529009
申请日：2003-09-25
申请人： Kenji Soejima , Noriko Mimura , Hiroaki Maeda , Chikateru Nozaki , Takayoshi Hamamoto , Tomohiro Nakagaki
发明人： Kenji Soejima , Noriko Mimura , Hiroaki Maeda , Chikateru Nozaki , Takayoshi Hamamoto , Tomohiro Nakagaki
IPC分类号： G01N33/53 , C12N5/20 , C07K16/00 , C07K16/28
CPC分类号： C12N9/6489 , C07K16/40
摘要： It is intended to provide an antibody showing immunoreactivity selectively to ADAMTS-13 and applications of this antibody in epitope analysis or diagnosis of an ADAMTS-13 autoantibody-positive patient. Alternatively, it is intended to provide a process for producing and use of a modified ADAMTS-13 molecule partially deleted aiming at the application in pharmaceutical products. An antibody specific for ADAMTS-13 which can be obtained from a warm-blooded animal immunized and sensitized with a polypeptide containing a part or the whole of ADAMTS-13 amino acid sequence; a process for producing an antibody comprising a step of immunizing and sensitizing a warm-blooded animal with a polypeptide containing a part or the whole of ADAMTS-13 amino acid sequence; use of the above-described antibody including a method of detecting and purifying ADAMTS-13; and a modified ADAMTS-13 molecule partially deleted are provided.
摘要翻译：旨在提供一种抗体，显示ADAMTS-13的免疫反应性和该抗体在ADAMTS-13自身抗体阳性患者的表位分析或诊断中的应用。或者，旨在提供一种制备和使用针对在药物产品中应用的部分缺失的修饰的ADAMTS-13分子的方法。对于ADAMTS-13特异的抗体，其可从用含有部分或全部ADAMTS-13氨基酸序列的多肽免疫并致敏的温血动物获得; 一种制备抗体的方法，其包括用含有部分或全部ADAMTS-13氨基酸序列的多肽对温血动物进行免疫和致敏的步骤; 使用上述抗体，包括检测和纯化ADAMTS-13的方法; 并提供部分缺失的修饰的ADAMTS-13分子。

99. 发明申请

US20090099338A1 Novel Protein Highly Producing Recombinant Animal Cell, Method for Preparing the Same, and Method for Mass-Producing Protein Using the Same 有权
标题翻译：新型蛋白质高产生重组动物细胞，其制备方法和使用该蛋白质大量生产蛋白质的方法
公开(公告)号：US20090099338A1
公开(公告)日：2009-04-16
申请号：US10576978
申请日：2004-10-21
申请人： Reiko Matsuyama , Hiroaki Maeda , Hitomi Shirahama , Takayuki Imamura , Yasuharu Kamachi
发明人： Reiko Matsuyama , Hiroaki Maeda , Hitomi Shirahama , Takayuki Imamura , Yasuharu Kamachi
IPC分类号： C07K14/75 , C12N5/10 , C12P21/02 , C07K14/755
CPC分类号： C12P21/02 , C12N2510/02
摘要： A gene encoding a production amount-potentiating factor is introduced into an animal cell to transform the cell. Alternatively, a protein production gene and the gene encoding the production amount-potentiating factor are introduced into the animal cell to transform the cell. Herein, as the production amount potentiating factor, there is used a factor having caspase activity inhibiting activity and/or protein biosynthesis activity potentiating action, for example, baculovirus P35. Further, the animal cell is cultured by a culturing method under a condition that apoptosis is not induced, so that a protein is mass-produced.
摘要翻译：将编码产生量增加因子的基因导入动物细胞以转化细胞。或者，将蛋白质生产基因和编码产生量增强因子的基因导入动物细胞以转化细胞。这里，作为生产量增强因子，使用具有半胱天冬酶活性抑制活性和/或蛋白质生物合成活性增强作用的因子，例如杆状病毒P35。此外，通过培养方法在不诱导细胞凋亡的条件下培养动物细胞，从而大量生产蛋白质。

100. 发明申请

US20080068191A1 Amplifier failure detection apparatus 有权
标题翻译：放大器故障检测装置
公开(公告)号：US20080068191A1
公开(公告)日：2008-03-20
申请号：US11790384
申请日：2007-04-25
申请人： Hiroaki Maeda , Takashi Ono , Yousuke Okazaki , Hirotake Honda , Hiroyuki Ezuka
发明人： Hiroaki Maeda , Takashi Ono , Yousuke Okazaki , Hirotake Honda , Hiroyuki Ezuka
IPC分类号： G08B21/00
CPC分类号： H03F1/3247 , H03F2201/3233 , H04B1/0466 , H04B2001/0416
摘要： An amplifier failure detection apparatus for a radio transmitter that has a function for compensating for amplifier distortion of the radio transmitter and a function for determining amplifier failure has occurred by detecting that the gain of an amplifier has dropped a set level or more, in which: a gain-detection unit detects the gain of the amplifier; an alarm-detection-level-generation unit, which has a table for storing alarm-detection levels that correspond to input-amplitude levels, generates an alarm-detection level that corresponds to an input-amplitude level; and a comparison unit compares the gain detected by the gain-detection unit with the alarm-detection level, and generates an alarm based on the comparison results.
摘要翻译：通过检测放大器的增益已经下降了设定值以上，已经发生了具有补偿无线电发射机的放大器失真的功能的放大器故障检测装置和用于确定放大器故障的功能，其中：增益检测单元检测放大器的增益; 具有用于存储对应于输入幅度电平的报警检测电平的表的报警检测电平生成单元生成与输入幅度电平对应的报警检测电平; 并且比较单元将由增益检测单元检测到的增益与报警检测水平进行比较，并且基于比较结果生成报警。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式