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91. 发明授权

US5223637A KS-506 compounds 失效
标题翻译： KS-506化合物
公开(公告)号：US5223637A
公开(公告)日：1993-06-29
申请号：US889388
申请日：1992-05-28
申请人： Kazutoshi Kuroda , Hiroshi Kase , Katsuhiko Ando , Isao Kawamoto , Toru Yasuzawa , Hiroshi Sano , Joji Goto , Koji Yamada
发明人： Kazutoshi Kuroda , Hiroshi Kase , Katsuhiko Ando , Isao Kawamoto , Toru Yasuzawa , Hiroshi Sano , Joji Goto , Koji Yamada
IPC分类号： C07C323/20 , C07C327/26 , C12P7/00
CPC分类号： C07C323/20 , C07C327/26 , C12P7/00
摘要： KS-506a, KS-506x and KS-506g having an activity to inhibit cyclic nucleotide phosphodiesterase and KS-506m and KS-506h having an activity to inhibit histamine release are produced by culturing a microorganism belonging to the genus Mortierella.
摘要翻译：通过培养属于被孢霉属属的微生物来产生具有抑制环核苷酸磷酸二酯酶的活性的KS-506a，KS-506x和KS-506g以及具有抑制组胺释放活性的KS-506m和KS-506h。

92. 发明授权

US5084453A 1-carboxy-1-vinyloxyimino aminothiazole cephalosporin derivatives 失效
标题翻译： 1-羧基-1-乙烯氧基亚氨基氨基噻唑头孢菌素衍生物
公开(公告)号：US5084453A
公开(公告)日：1992-01-28
申请号：US265458
申请日：1988-10-13
申请人： Susumu Nakagawa , Ryuji Mitomo , Koji Yamada , Norikazu Otake , Fumio Nakano , Akira Asai , Satoru Kuroyanagi , Yoshiharu Tanaka , Moriaki Ishikawa , Ryosuke Ushijima
发明人： Susumu Nakagawa , Ryuji Mitomo , Koji Yamada , Norikazu Otake , Fumio Nakano , Akira Asai , Satoru Kuroyanagi , Yoshiharu Tanaka , Moriaki Ishikawa , Ryosuke Ushijima
IPC分类号： A61K31/545 , C07D235/28 , C07D263/46 , C07D263/58 , C07D271/10 , C07D271/113 , C07D277/20 , C07D277/36 , C07D277/40 , C07D277/56 , C07D285/12 , C07D285/125 , C07D501/22 , C07D501/24 , C07D501/34 , C07D501/36 , C07D501/46
CPC分类号： C07D263/58 , C07D235/28 , C07D263/46 , C07D271/113 , C07D277/36 , C07D277/56 , C07D277/587 , C07D285/125 , Y02P20/55
摘要： The present invention relates to a compound having the formula: ##STR1## wherein R is a hydrogen atom, a carboxyl-protecting group or a negative charge and Q is a hydrogen atom, a halogen atom, a hydroxyl group, an acetoxy group, a carbamoyl group, an azide group, a substituted or unsubstituted quarternary ammonio group or a substituted or unsubstituted heterocyclic thio group having at least one hetero atom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom, or a non-toxic salt or physiologically hydrolyzable non-toxic ester thereof; a process for producing it; and an antibacterial agent comprising it as an active ingredient.Further, the present invention also relates to a compound having the formula: ##STR2## wherein R.sup.3 is a hydrogen atom or an amino-protecting group, and each of R.sup.4 and R.sup.5 which may be the same or different is a hydrogen atom or a carboxyl-protecting group, or a salt thereof; and a process for producing it.

93. 发明授权

US4990693A Novel substances KS-504a, KS-504b, KS-504d and KS-504e and process for their preparation 失效
公开(公告)号：US4990693A
公开(公告)日：1991-02-05
申请号：US465892
申请日：1990-01-16
申请人： Satoshi Nakanishi , Koji Yamada , Katsuhiko Ando , Isao Kawamoto , Toru Yasuzawa , Hiroshi Sano , Noriaki Hirayama , Hiroshi Kase , Joji Goto , Etsuyo Shimizu
发明人： Satoshi Nakanishi , Koji Yamada , Katsuhiko Ando , Isao Kawamoto , Toru Yasuzawa , Hiroshi Sano , Noriaki Hirayama , Hiroshi Kase , Joji Goto , Etsuyo Shimizu
IPC分类号： C07C35/48 , C07C45/58 , C07C47/46 , C07D303/48 , C12P7/02 , C12P7/24 , C12P17/02
CPC分类号： C12R1/645 , C07C35/48 , C07C45/58 , C07C47/46 , C07D303/48 , C12P17/02 , C12P7/02 , C12P7/24
摘要： Novel physiologically active substances KS-504a, KS-504b and KS-504d having a vasodilative activity and a novel physiologically active substance KS-504e having an activity to inhibit histamine secretion are produced by culturing a microorganism of the genus Mollisia.

94. 发明授权

US4977994A Fare adjustment machine for prepaid card type tickets 失效
标题翻译：票价调整机用于预付卡型票
公开(公告)号：US4977994A
公开(公告)日：1990-12-18
申请号：US327871
申请日：1989-03-23
申请人： Masaharu Adachi , Yoshiaki Uematsu , Haruo Nagano , Koji Yamada
发明人： Masaharu Adachi , Yoshiaki Uematsu , Haruo Nagano , Koji Yamada
IPC分类号： G07B11/00 , G07G5/00
CPC分类号： G07G5/00 , G07B11/00
摘要： A fare adjustment machine, wherein a card conveyor for carrying a fare-adjusted card and a receipt conveyor for carrying a printed receipt are disposed with their passages intersecting each other so that the surfaces of the card and the receipt cross each other perpendicularly. The receipt is held at one-side at the intersection by a clamp mechanism and released from the receipt conveyor by a release mechanism. The receipt thus held is pushed at its lower side by the card carried by the card conveyor so that it falls down flat on top of the card, and the card and receipt are then then simultaneously discharged from the machine.

95. 发明授权

US4923986A Derivatives of physiologically active substance K-252 失效
标题翻译：生理活性物质K-252的衍生物
公开(公告)号：US4923986A
公开(公告)日：1990-05-08
申请号：US273519
申请日：1988-11-08
申请人： Chikara Murakata , Akira Sato , Mitsuru Takahashi , Eiji Kobayashi , Makoto Morimoto , Shiro Akinaga , Tadashi Hirata , Kenichi Mochida , Hiroshi Kase , Koji Yamada , Kazuyuki Iwashashi
发明人： Chikara Murakata , Akira Sato , Mitsuru Takahashi , Eiji Kobayashi , Makoto Morimoto , Shiro Akinaga , Tadashi Hirata , Kenichi Mochida , Hiroshi Kase , Koji Yamada , Kazuyuki Iwashashi
IPC分类号： A61K31/55 , C07D20060101 , C07D498/22
CPC分类号： C07D498/22
摘要： The present invention relates to novel derivatives of K-252, (8R*, 9S*, 11S*)-(-)-9-hydroxy-9-methoxycarbonyl-8-methyl-2,3,9,10-tetrahydro-8,11-epoxy-1H,8H, 11H-2,7b,11a-triazadibenzo[a,g]cycloocta-[c,d,e,]trinden-1-one, and the compounds are represented by formula (I): ##STR1## wherein W.sub.1, W.sub.2, R.sup.1, R.sup.2, R.sup.3, R.sup.4, X and Y represent various substituents. The compounds are physiologically active substances that inhibit protein kinase C and exhibit an antitumor activity, and are useful as medicines.

96. 发明授权

US4883868A 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives 失效
标题翻译： 7-氨基-3-（取代的异二氢吲哚鎓）甲基-3-头孢烯衍生物
公开(公告)号：US4883868A
公开(公告)日：1989-11-28
申请号：US64462
申请日：1987-06-22
申请人： Susumu Nakagawa , Ryosuke Ushijima , Fumio Nakano , Koji Yamada , Eiichi Mano
发明人： Susumu Nakagawa , Ryosuke Ushijima , Fumio Nakano , Koji Yamada , Eiichi Mano
IPC分类号： A61K31/545 , C07D501/46
CPC分类号： C07D501/46 , C07D501/18 , C07D501/38 , Y02P20/55
摘要： A compound having the formula: ##STR1## wherein R.sup.1 is an amino group or a protected amino group, R.sup.2 is a hydrogen atom or a protecting group for a hydroxyl group, R.sup.3 represents negative charge, a hydrogen atom or a protecting group for a carboxyl group, and n is 0 or 1, and a salt thereof.
摘要翻译：具有下式的化合物：其中R1是氨基或被保护的氨基，R2是氢原子或羟基的保护基，R3代表负电荷，氢原子或保护基羧基，n为0或1，及其盐。

97. 发明授权

US4843831A Refrigerator control system 失效
标题翻译：冰箱控制系统
公开(公告)号：US4843831A
公开(公告)日：1989-07-04
申请号：US160014
申请日：1988-02-24
申请人： Koji Yamada
发明人： Koji Yamada
IPC分类号： F25B47/02 , F25B5/02 , F25D11/00 , F25D21/00 , F25D21/06
CPC分类号： F25B5/02 , F25D11/006 , F25D21/008 , F25B2600/2511 , F25B2700/2117 , F25D2400/04 , F25D2700/12 , F25D2700/122
摘要： A cold accumulation type refrigerator having an improved control system for controlling its defrost cycle. The refrigerator includes a main evaporator for producing cold air, a cooling command signal generating device for generating a cooling command signal when a refrigerator compartment is required to be cooled, a clock device for generating a time data, a refrigerating cycle for cooling the main evaporator in accordance with the cooling command signal and the cold-accumulation material in accordance with the time data from the clock device, and a defrost control device for removing frost deposited on the main evaporator. The defrost control device counts cooling operation time of the evaporator in response to the cooling command signal. If the refrigerator is a fan cool type refrigerator whose evaporator is provided with a cold air circulation fan, the defrost control device counts the operation time of the fan, and when a prescribed time count, such as twelve hours, has been completed, the defrost control device generates a defrost starting signal, whereby a proper defrosting operation is carried out even in the cold-accumulation type refrigerator.
摘要翻译：一种冷堆式冰箱，具有改进的控制系统，用于控制其除霜循环。冰箱包括用于产生冷空气的主蒸发器，用于在冷藏室需要冷却时产生冷却指令信号的冷却指令信号发生装置，用于产生时间数据的时钟装置，用于冷却主蒸发器的制冷循环根据来自时钟装置的时间数据的冷却指令信号和冷堆积材料，以及用于除去沉积在主蒸发器上的霜的除霜控制装置。除霜控制装置响应于冷却指令信号计算蒸发器的冷却操作时间。如果冰箱是蒸发器设置有冷风循环风扇的风扇式冷藏式冰箱，则除霜控制装置对风扇的运转时间进行计数，在规定时间计数（如十二小时）完成后，除霜控制装置产生除霜启动信号，由此即使在冷堆积型冰箱中也执行适当的除霜操作。

98. 发明授权

US4794655A Truck type patient-moving device 失效
标题翻译：卡车式病人移动装置
公开(公告)号：US4794655A
公开(公告)日：1989-01-03
申请号：US31668
申请日：1987-03-30
申请人： Akihiro Ooka , Kenji Okamoto , Koji Yamada
发明人： Akihiro Ooka , Kenji Okamoto , Koji Yamada
IPC分类号： A61G7/10 , A61G7/08
CPC分类号： A61G7/1019 , A61G7/103 , A61G7/1032 , A61G7/1046 , A61G7/1057 , A61G2200/32 , A61G2200/34
摘要： A patient moving device includes a movable support means, a loading-unloading means disposed on the support means for loading and unloading a patient and provided with a horizontal base plate held on the support means and an insertion plate inserted under a patient and adapted to move in and out of the horizontal plate, and a means for holding the horizontal base plate on the support means so as to be capable of being advanced and retracted in the same direction as the insertion plate.
摘要翻译：患者移动装置包括可移动支撑装置，装载卸载装置，设置在支撑装置上，用于装载和卸载患者，并且设置有保持在支撑装置上的水平底板，以及插入在患者身下并适于移动的插入板在水平板内和外面，以及用于将水平基板保持在支撑装置上以便能够沿与插入板相同的方向前进和后退的装置。

99. 发明授权

US4495192A 1-Substituted 1,4-dihydropyridines 失效
标题翻译： 1-取代的1,4-二氢吡啶
公开(公告)号：US4495192A
公开(公告)日：1985-01-22
申请号：US490167
申请日：1983-04-29
申请人： Kenji Muto , Yoshinori Takemoto , Takao Hatta , Tamotsu Hashimoto , Koji Yamada , Minoru Watanabe
发明人： Kenji Muto , Yoshinori Takemoto , Takao Hatta , Tamotsu Hashimoto , Koji Yamada , Minoru Watanabe
IPC分类号： A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/455 , A61P9/08 , A61P9/10 , A61P9/12 , C07C67/00 , C07C201/00 , C07C205/56 , C07D211/90 , C07D211/94 , C07D401/12 , C07D405/12 , C07D409/12
CPC分类号： C07D405/12 , C07C205/56 , C07D211/90 , C07D211/94 , C07D409/12 , Y10S514/929
摘要： A vasodilating or anti-hypertensive composition comprises a pharmaceutical carrier and an effective amount of a 1,4-dihydropyridine compound as an active ingredient. The 1,4-dihydropyridine compound may be represented by the following general formula: ##STR1## wherein R'.sub.1 and R'.sub.4 represent a hydrogen atom, R'.sub.2 and R'.sub.3 represent an alkyl group having 1-5 carbon atoms or a substituted heterocyclic group wherein a substituent is an N-benzylpiperidyl group, R'.sub.5 represents a nitro group, and R'.sub.6 and R'.sub.7 represent an alkyl group having 1-5 carbon atoms.
摘要翻译：血管舒张或抗高血压组合物包含药物载体和有效量的1,4-二氢吡啶化合物作为活性成分。 1,4-二氢吡啶化合物可以由以下通式表示：其中R'1和R'4代表氢原子，R'2和R'3代表具有1- 5个碳原子或取代的杂环基，其中取代基是N-苄基哌啶基，R'5表示硝基，R'6和R'7表示具有1-5个碳原子的烷基。

100. 发明授权

US09815995B2 Ink for ink-jet printing, printed cylindrical containers and method for producing the same 有权
公开(公告)号：US09815995B2
公开(公告)日：2017-11-14
申请号：US14373394
申请日：2013-01-31
申请人： Koji Yamada , Kenji Hayashi , Yukiko Saito , Hiroshi Shimomura
发明人： Koji Yamada , Kenji Hayashi , Yukiko Saito , Hiroshi Shimomura
IPC分类号： C09D11/36 , C09D11/10 , C09D11/322 , C09D11/38 , C08K13/02 , B41J2/01 , B41M5/00 , B41M7/00
CPC分类号： C09D11/36 , B41J2/01 , B41M5/0088 , B41M7/009 , C08K13/02 , C09D11/10 , C09D11/322 , C09D11/38 , Y10T428/1352
摘要： An ink for ink-jet printing used for ink-jet printing images onto the ink non-absorptive surfaces of cylindrical containers, and comprising at least a water-soluble solvent, a coloring material, a surfactant, a thickener and/or a binder resin, the coloring material being contained in an amount of 5 to 20% by weight, the surfactant in an amount of 0.1 to 5% by weight, the thickener in an amount of not more than 10% by weight, and the binder resin being contained in an amount of not more than 30% by weight. Owing to its ink-jet printability, the ink for ink-jet printing of the invention can be favorably used for printing images on the non-absorptive cylindrical containers such as seamless cans that are used for containing beverages and foods.

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