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    • 92. 发明申请
    • METHOD FOR MAINTAINING ACCESS TO A BIOPSY SITE
    • 维持对生物场地访问的方法
    • US20110201966A1
    • 2011-08-18
    • US13095304
    • 2011-04-27
    • Paul LubockMichael L. Jones
    • Paul LubockMichael L. Jones
    • A61B10/02
    • A61M29/02A61B10/0041A61B17/0218A61B90/02A61B2017/00557A61B2017/00796A61B2090/3908A61M25/10A61M29/00A61M2025/1095A61N5/1015
    • A method for maintaining access to a biopsy site within a patient, includes forming a passageway from an opening in an exterior site on the patient to a desired location for a biopsy specimen within the patient; removing a tissue specimen from the desired location thereby leaving a biopsy cavity; providing a temporary catheter having an elongate shaft, a flexible proximal shaft section, and a distal shaft section having a cavity filling member thereon; inserting the cavity filling member on the distal shaft section into the biopsy cavity; inflating the cavity filling member after inserting the cavity filling member within the biopsy cavity, but before closing the opening, using the flexible proximal shaft section; placing the flexible proximal shaft section at an intracorporeal location; and closing the opening so as to seal the passageway.
    • 一种用于维持进入患者体内的活检部位的方法,包括从病人的外部位置的开口形成通道,以在患者体内用于活检标本的期望位置; 从所需位置移除组织标本,从而留下活检腔; 提供具有细长轴,柔性近轴部分和在其上具有空腔填充构件的远端轴部分的临时导管; 将所述空腔填充构件插入所述远端轴部分到所述活检腔中; 将空腔填充构件插入到活检腔内,但是在使用柔性近端轴段关闭开口之前使空腔填充构件膨胀; 将柔性近轴部分放置在体内位置; 并关闭开口以密封通道。
    • 93. 发明授权
    • Fibrous marker and intracorporeal delivery thereof
    • 纤维标记和体内递送
    • US07983734B2
    • 2011-07-19
    • US10444770
    • 2003-05-23
    • Michael L. JonesPaul LubockLloyd H. Malchow
    • Michael L. JonesPaul LubockLloyd H. Malchow
    • A61B6/00
    • A61B90/39A61B17/0057A61B2017/00637A61B2017/00898A61B2090/3908A61B2090/392A61B2090/3925A61B2090/3954A61B2090/3987
    • The invention is directed to an intracorporeal marker, a delivery device and assembly for such marker and the method of delivering one or more of the markers to an intracorporeal location within a patient. The marker is a body formed at least in part of a bioabsorbable fibrous material such as a fibrous mat or fabric. The delivery devices preferably also include one or more bioabsorbable short term markers which are configured to expand within the body cavity due to contacting a body fluid. The fibrous marker has a radiographically detectable member which preferably hold a portion of the fibrous body in a compressed condition. Preferably, the fibrous marker has a fibrous felt core formed of bioabsorbable material with a fabric jacket formed of bioabsorbable material. Therapeutic, diagnostic and binding agents may be incorporated into the fibrous body of the marker.
    • 本发明涉及一种体内标记物,用于这种标记的递送装置和装置,以及将一种或多种标记递送到患者体内位置的方法。 标记物是形成至少部分生物可吸收纤维材料如纤维垫或织物的主体。 递送装置优选还包括一个或多个生物可吸收的短期标记物,其构造成由于接触体液而在体腔内膨胀。 纤维标记具有可放射线检测的构件,其优选地将纤维体的一部分保持在压缩状态。 优选地,纤维标记物具有由生物可吸收材料形成的纤维毡芯,其具有由生物可吸收材料形成的织物护套。 可以将治疗性,诊断性和结合剂掺入标记物的纤维体内。
    • 94. 发明申请
    • Soft body catheter with low friction lumen
    • 软体导管低摩擦腔
    • US20100048979A1
    • 2010-02-25
    • US12589765
    • 2009-10-28
    • Michael L. JonesFrank R. Louw
    • Michael L. JonesFrank R. Louw
    • A61M36/12B05D7/00
    • A61N5/1015A61L29/085A61M2025/0047
    • The disclosure is directed to radiation catheter devices, methods for controlled application of irradiation to tissue at a body site, such as a cavity formed after removal of tissue, e.g. cancer, using such radiation catheter devices, solutions for forming a more lubricious luminal surface and method for lining lumens of such devices to improve the frictional characteristics thereof. The catheter device includes a flexible elongated shaft which is formed of low durometer polymeric material, which can be readily folded or coiled for securing the shaft to or under the skin of the patient and a radiation lumen lined with high durometer polymeric material to improve the frictional characteristics. The elongated shaft has at least one inner lumen for receiving a radiation source which has a layer of high durometer polymeric material that provides lower surface friction to facilitate advancement of a radiation source therein.
    • 本公开涉及辐射导管装置,用于受控地应用照射到身体部位的组织的方法,例如在去除组织之后形成的空腔,例如, 癌症,使用这种辐射导管装置,用于形成更加光滑的腔表面的解决方案以及用于衬里这些装置的流明以提高其摩擦特性的方法。 导管装置包括柔性细长轴,其由低硬度聚合物材料形成,其可以容易地折叠或卷绕以将轴固定到患者的皮肤上或皮下,以及衬有高硬度聚合物材料的辐射腔,以改善摩擦 特点 细长轴具有用于接收辐射源的至少一个内腔,辐射源具有提供较低表面摩擦以便促进其中的辐射源的高硬度聚合材料层。
    • 95. 发明申请
    • Tissue irradiation
    • 组织照射
    • US20090209805A1
    • 2009-08-20
    • US12386100
    • 2009-04-14
    • Paul LubockMichael L. Jones
    • Paul LubockMichael L. Jones
    • A61M36/04
    • A61N5/1015A61B2017/3419A61N2005/1005
    • Devices and methods are disclosed for treatment to tissue surrounding a body cavity or other intracorporeal site, such as after removal of tissue, e.g. cancer. Such a device includes a treatment location on a distal portion of the device with one or more radiation shielding components that partially encircle a radiation source at the treatment location to control emitted radiation from the radiation source. The device minimizes radiation damage to healthy tissue surrounding the body cavity or other site while irradiating tissue not shielded by the radiation shielding components. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location to seal the passageway leading to the body cavity.
    • 公开了用于治疗围绕体腔或其他体内部位的组织的装置和方法,例如在去除组织后,例如, 癌症。 这种装置包括在装置的远端部分上的处理位置,其中一个或多个辐射屏蔽部件在处理位置部分地环绕辐射源以控制来自辐射源的辐射。 该装置最小化对体腔或其他部位周围的健康组织的辐射损伤,同时辐射未被辐射屏蔽部件屏蔽的组织。 体现本发明特征的装置可包括密封构件,该密封构件位于靠近处理位置的装置的轴上的位置处,以密封通向体腔的通道。
    • 96. 发明申请
    • Treatment of a body cavity
    • 治疗体腔
    • US20080188705A1
    • 2008-08-07
    • US12012744
    • 2008-01-31
    • Paul LubockMichael L. Jones
    • Paul LubockMichael L. Jones
    • A61M36/12A61M36/04
    • A61N5/1015A61B2017/3419A61N2005/1005
    • Devices and methods are provided for controlled application of a treatment to tissue adjacent a body cavity, such as after removal of tissue, e.g. cancer. A device embodying features of the invention includes one or more radiation shielding components to control emitted radiation from a radiation source to minimize radiation damage to healthy portions of the body cavity. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location therein to seal the passageway leading to the body cavity. Methods for treating a body cavity include methods for delivering a radiation source to a body cavity while minimizing damaging irradiation of healthy tissue.
    • 提供了设备和方法,用于控制对身体周围的组织进行治疗,例如在去除组织后,例如, 癌症。 体现本发明特征的装置包括一个或多个辐射屏蔽组件,用于控制来自辐射源的辐射,以最小化对体腔健康部分​​的辐射损伤。 体现本发明特征的装置可以包括密封构件,该密封构件位于装置的轴的位置处,靠近其中的处理位置以密封通向体腔的通道。 用于治疗体腔的方法包括将辐射源递送到体腔的方法,同时最小化对健康组织的损伤性照射。