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91. 发明授权

US06316403B1 Methods for treating an ischemic disorder and improving stroke outcome 失效
标题翻译：治疗缺血性疾病和改善中风结局的方法
公开(公告)号：US06316403B1
公开(公告)日：2001-11-13
申请号：US09269426
申请日：1999-06-25
申请人： David J. Pinsky , David Stern , Ann Marie Schmidt , Eric A. Rose , E. Sander Connolly , Robert A. Solomon , Charles J. Prestigiacomo
发明人： David J. Pinsky , David Stern , Ann Marie Schmidt , Eric A. Rose , E. Sander Connolly , Robert A. Solomon , Charles J. Prestigiacomo
IPC分类号： A61K3800
CPC分类号： A61K38/4846 , C07K14/70564 , C07K16/2854
摘要： The present invention provides for a method of treating an ischemic disorder in a subject which comprises administering to the subject a pharmaceutically acceptable form of inactivated Factor IX in a sufficient amount over a sufficient period of time to inhibit coagulation so as to treat the ischemic disorder in the subject.
摘要翻译：本发明提供了治疗受试者的缺血性疾病的方法，其包括在足够的时间内以足够的时间向受试者施用药学上可接受的形式的灭活因子IX以抑制凝血，以便治疗缺血性疾病主题。

92. 发明授权

US06271957B1 Methods involving direct write optical lithography 失效
标题翻译：涉及直写光刻的方法
公开(公告)号：US06271957B1
公开(公告)日：2001-08-07
申请号：US09318775
申请日：1999-05-26
申请人： Calvin F. Quate , David Stern
发明人： Calvin F. Quate , David Stern
IPC分类号： G02B2608
CPC分类号： G03F7/70291 , B01J19/0046 , B01J2219/00353 , B01J2219/00439 , B01J2219/00527 , B01J2219/00529 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00689 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y30/00 , C40B40/06 , C40B60/14 , G03F7/70283 , G03F7/704
摘要： An improved optical photolithography system and method provides predetemined light patterns generated by a direct write system without the use of photomasks. The Direct Write System provides predetermined light patterns projected on the surface of a substrate (e.g., a wafer) by using a computer controlled component for dynamically generating the predetermined light pattern, e.g., a spatial light modulator. Image patterns are store in computer and through electronic control of the spatial light modulator directly illuminate the wafer to define a portion of the polymer array, rather than being defined by a pattern on a photomask. Thus, in the Direct Write System each pixel is illuminated with an optical beam of suitable intensity and the imaging (printing) of an individual feature is determined by computer control of the spatial light modulator at each photolithographic step without the use of a photomask. The Direct Write System including a spatial light modulator is particularly useful in the synthesis of DNA arrays and provides an efficient element for polymer array synthesis by using spatial light modulators to generate a predetermined light pattern that defines the image patterns of a polymer array to be deprotected.
摘要翻译：改进的光学光刻系统和方法提供由直接写入系统产生的预先设定的光图案，而不使用光掩模。直接写入系统通过使用用于动态生成预定光图案的计算机控制部件（例如空间光调制器）来提供投影在基板（例如，晶片）的表面上的预定光图案。图像图案存储在计算机中，并且通过空间光调制器的电子控制直接照亮晶片以限定聚合物阵列的一部分，而不是由光掩模上的图案限定。因此，在直写系统中，每个像素用适当强度的光束照射，并且通过在每个光刻步骤的计算机控制空间光调制器而不使用光掩模来确定单个特征的成像（打印）。包括空间光调制器在内的直接写入系统在DNA阵列的合成中特别有用，并且通过使用空间光调制器产生限定要去保护的聚合物阵列的图像图案的预定光图案，为聚合物阵列合成提供有效元素。

93. 发明授权

US06207960B1 System and methods for detection of labeled materials 有权
标题翻译：用于检测标记材料的系统和方法
公开(公告)号：US06207960B1
公开(公告)日：2001-03-27
申请号：US09295214
申请日：1999-04-21
申请人： David Stern
发明人： David Stern
IPC分类号： G01N2164
CPC分类号： G01N21/6452 , B01J2219/00529 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , C12Q1/6834 , C12Q1/6876 , C12Q1/6883 , G01N21/6428 , G01N21/6458 , G02B21/0048 , G02B21/0072 , G02B21/0076 , G02B21/0084
摘要： Labeled targets on a support synthesized with polymer sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, can be detected by exposing marked regions of sample to radiation from a source and detecting the emission therefrom, and repeating the steps of exposition and detection until the sample is completely examined.
摘要翻译：在根据美国专利No.5,623,997中公开的方法的已知位置处的聚合物序列合成的载体上的标记靶标。可以通过将样品的标记区域暴露于来自源的辐射并检测其中的发射来检测，并重复说明和检测步骤直到样品被完全检查来检测。

94. 发明授权

US5981956A Systems and methods for detection of labeled materials 失效
公开(公告)号：US5981956A
公开(公告)日：1999-11-09
申请号：US856642
申请日：1997-05-15
申请人： David Stern
发明人： David Stern
IPC分类号： C12Q1/68 , G01N21/64 , G02B21/00
CPC分类号： G01N21/6452 , C12Q1/6834 , C12Q1/6876 , C12Q1/6883 , G01N21/6428 , G01N21/6458 , G02B21/0048 , G02B21/0072 , G02B21/0076 , G02B21/0084 , B01J2219/00529 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659
摘要： Labeled targets on a support synthesized with polymer sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, can be detected by exposing marked regions of sample to radiation from a source and detecting the emission therefrom, and repeating the steps of exposition and detection until the sample is completely examined.

95. 发明授权

US5834758A Method and apparatus for imaging a sample on a device 失效
公开(公告)号：US5834758A
公开(公告)日：1998-11-10
申请号：US708335
申请日：1996-09-04
申请人： Mark Trulson , David Stern , Peter Fiekowsky , Richard Rava , Ian Walton , Stephen P. A. Fodor
发明人： Mark Trulson , David Stern , Peter Fiekowsky , Richard Rava , Ian Walton , Stephen P. A. Fodor
IPC分类号： G01N21/64 , G01N21/63
CPC分类号： G01N21/6452 , G01N21/6428 , G01N21/6456 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00637 , B01J2219/00659 , B01J2219/00702 , G01N2021/6417 , G01N2021/6423 , G01N2021/6441
摘要： Labeled targets on a support synthesized with polymer sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, can be detected by exposing selected regions of sample 1500 to radiation from a source 1100 and detecting the emission therefrom, and repeating the steps of exposition and detection until the sample is completely examined.

96. 发明授权

US4056213A Pressurized dispenser for aqueous emulsion paints 失效
标题翻译：用于水性乳液漆的加压分配器
公开(公告)号：US4056213A
公开(公告)日：1977-11-01
申请号：US540812
申请日：1975-01-14
申请人： David Stern
发明人： David Stern
IPC分类号： B05B1/34 , B05B11/00 , B05B15/02 , B65D83/14 , B65D83/16 , B65D35/28
CPC分类号： B65D83/20 , B05B1/3436 , B05B15/02 , B05B15/0208 , B65D83/345 , B65D83/40 , Y10S524/903
摘要： The invention relates to an improved pressurized dispenser for aqueous emulsion paints whose vehicle consists of a major proportion of water and a minor proportion of an acrylic polymer or polyvinyl acetate-acrylic copolymer, the emulsion being discharged as a fine spray but without foaming and without clogging of the nozzle orifice by dried paint even after repeated fractional discharges. The paint is contained in a collapsible piston within the pressurized container and the stream of paint discharging upon opening of the valve of the container is broken up by a mechanical breaker before being discharged through the nozzle in the form of a fine spray devoid of propellant, the latter being contained under pressure between the piston and the wall of the container. Means are provided in the form of a cap for the nozzle so constructed so as to reduce or substantially eliminate the space about the nozzle after use of portions of the contents of the package to prevent drying out of any paint adhering to the nozzle and thereby clogging the nozzle.
摘要翻译：本发明涉及一种用于水性乳液涂料的改进的加压分配器，其载体由主要部分的水和少量的丙烯酸聚合物或聚乙酸乙烯酯 - 丙烯酸共聚物组成，乳液作为细小的喷雾排出，但没有起泡并且没有堵塞即使经过反复的分级放电，也可以通过干漆进行喷嘴孔。油漆被包含在加压容器内的可折叠的活塞中，并且在容器的阀打开时排出的油漆流被机械式破碎机分解，然后通过喷嘴以没有推进剂的细微喷雾的形式排出，后者被包含在活塞和容器的壁之间的压力下。设置为用于喷嘴的盖的形式的装置，其被构造成在使用包装的内容物的部分之后减少或基本上消除喷嘴周围的空间，以防止粘附到喷嘴上的任何涂料的干燥，从而堵塞喷嘴。

97. 发明授权

US4005167A Plasticizing apparatus 失效
标题翻译：增塑装置
公开(公告)号：US4005167A
公开(公告)日：1977-01-25
申请号：US320286
申请日：1973-01-02
申请人： David Stern
发明人： David Stern
IPC分类号： B29C45/13 , B29C45/16 , B29C45/47 , B29C47/56 , B29C47/58 , B29F1/12
CPC分类号： B29C45/1606 , B29C45/13 , B29C45/47 , B29C47/56 , B29C47/0009
摘要： A plasticizing apparatus having a plurality of plasticizing chambers arranged to feed a common outlet consecutively, or concurrently, or serially, the arrangement being such that while one of the chambers is being used to feed the outlet, the other or another chamber can be refilled with material to be plasticized, and can be used to plasticize that material.
摘要翻译：一种塑化装置，其具有多个塑化室，其布置成连续或同时或串联地供给公共出口，使得当所述室中的一个被用于供给出口时，可以将另一个室或另一个室重新填充要塑化的材料，并且可以用于塑化该材料。

98. 发明授权

US08788578B2 Method and apparatus for customized provisioning of on-line application channels 有权
标题翻译：用于在线应用频道定制配置的方法和装置
公开(公告)号：US08788578B2
公开(公告)日：2014-07-22
申请号：US13180375
申请日：2011-07-11
申请人： Anthony Wood , David Stern , David Westerhoff , Bill Ataras , Mark Goodwin , Aaron Graham , Matt Emerson , Kevin Phillips
发明人： Anthony Wood , David Stern , David Westerhoff , Bill Ataras , Mark Goodwin , Aaron Graham , Matt Emerson , Kevin Phillips
IPC分类号： G06F15/16
CPC分类号： H04L65/4069 , H04L65/1063 , H04L65/4076
摘要： A method for a computer system includes receiving an identifier associated with a client streaming player, determining one or more attributes associated with the identifier from a data structure in response to the identifier, determining available channels from a plurality of channels that are to be made available to the client streaming player in response to the identifier, wherein available channels comprises a first channel, but not the second channel, determining a first graphical identifier associated with the first channel, providing the first graphical identifier to the client streaming player, receiving a user selection of the first graphical identifier indicating a user request to associate the first channel with the computer system, and providing an indicator of a server network address associated with the first channel to the client streaming player.
摘要翻译：一种用于计算机系统的方法包括：接收与客户端流播放器相关联的标识符，响应于所述标识符从数据结构确定与所述标识符相关联的一个或多个属性，从多个信道中确定可用信道响应于所述标识符到所述客户端流播放器，其中可用信道包括第一信道而不是所述第二信道，确定与所述第一信道相关联的第一图形标识符，向所述客户端流播放器提供所述第一图形标识符，接收用户选择第一图形标识符，指示用户请求将第一频道与计算机系统相关联，以及向客户端流播放器提供与第一频道相关联的服务器网络地址的指示符。

99. 发明授权

US08706653B2 Knowledge corroboration 有权
标题翻译：知识证明
公开(公告)号：US08706653B2
公开(公告)日：2014-04-22
申请号：US12963352
申请日：2010-12-08
申请人： Gjergji Kasneci , Jurgen Anne Francois Marie Van Gael , Thore Kraepel , Ralf Herbrich , David Stern
发明人： Gjergji Kasneci , Jurgen Anne Francois Marie Van Gael , Thore Kraepel , Ralf Herbrich , David Stern
IPC分类号： G06F15/18
CPC分类号： G06N7/005
摘要： Knowledge corroboration is described. In an embodiment many judges provide answers to many questions so that at least one answer is provided to each question and at least some of the questions have answers from more than one judge. In an example a probabilistic learning system takes features describing the judges or the questions or both and uses those features to learn an expertise of each judge. For example, the probabilistic learning system has a graphical assessment component which aggregates the answers in a manner which takes into account the learnt expertise in order to determine enhanced answers. In an example the enhanced answers are used for knowledge base clean-up or web-page classification and the learnt expertise is used to select judges for future questions. In an example the probabilistic learning system has a logical component that propagates answers according to logical relations between the questions.
摘要翻译：描述知识佐证。在一个实施例中，许多法官为许多问题提供答案，使得至少一个答案被提供给每个问题，并且至少一些问题具有来自多于一个法官的答案。在一个例子中，概率学习系统采用描述法官或问题或两者的特征，并使用这些特征来学习每个法官的专业知识。例如，概率学习系统具有图形评估组件，其以考虑到所学习的专业知识的方式聚集答案，以便确定增强的答案。在一个例子中，增强的答案用于知识库清理或网页分类，并且学习的专业知识用于为将来的问题选择法官。在一个例子中，概率学习系统具有根据问题之间的逻辑关系传播答案的逻辑组件。

100. 发明申请

US20120150771A1 Knowledge Corroboration 有权
标题翻译：知识佐证
公开(公告)号：US20120150771A1
公开(公告)日：2012-06-14
申请号：US12963352
申请日：2010-12-08
申请人： Gjergji Kasneci , Jurgen Ann Francois Marie Van Gael , Thore Graepel , Ralf Herbrich , David Stern
发明人： Gjergji Kasneci , Jurgen Ann Francois Marie Van Gael , Thore Graepel , Ralf Herbrich , David Stern
IPC分类号： G06F15/18
CPC分类号： G06N7/005
摘要： Knowledge corroboration is described. In an embodiment many judges provide answers to many questions so that at least one answer is provided to each question and at least some of the questions have answers from more than one judge. In an example a probabilistic learning system takes features describing the judges or the questions or both and uses those features to learn an expertise of each judge. For example, the probabilistic learning system has a graphical assessment component which aggregates the answers in a manner which takes into account the learnt expertise in order to determine enhanced answers. In an example the enhanced answers are used for knowledge base clean-up or web-page classification and the learnt expertise is used to select judges for future questions. In an example the probabilistic learning system has a logical component that propagates answers according to logical relations between the questions.
摘要翻译：描述知识佐证。在一个实施例中，许多法官为许多问题提供答案，使得至少一个答案被提供给每个问题，并且至少一些问题具有来自多于一个法官的答案。在一个例子中，概率学习系统采用描述法官或问题或两者的特征，并使用这些特征来学习每个法官的专业知识。例如，概率学习系统具有图形评估组件，其以考虑到所学习的专业知识的方式聚集答案，以便确定增强的答案。在一个例子中，增强的答案用于知识库清理或网页分类，并且学习的专业知识用于为将来的问题选择法官。在一个例子中，概率学习系统具有根据问题之间的逻辑关系传播答案的逻辑组件。

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