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91. 发明授权

US07738953B2 Method and device for preventing plaque formation in coronary arteries 失效
标题翻译：用于预防冠状动脉斑块形成的方法和装置
公开(公告)号：US07738953B2
公开(公告)日：2010-06-15
申请号：US11203756
申请日：2005-08-15
申请人： Qingsheng Zhu , Avram Scheiner , Julio C. Spinelli
发明人： Qingsheng Zhu , Avram Scheiner , Julio C. Spinelli
IPC分类号： A61N1/36
CPC分类号： A61N1/326 , A61N1/0587
摘要： A method and device for preventing plaque build-up in a coronary artery includes providing an electrical field generating device, and generating an electrical field in the coronary artery to prevent plaque build-up in the coronary artery. The method further includes sensing the heart rhythm and generating the electrical field after a depolarization wave in the heart. The electrical field is generated by circuitry, in one embodiment implanted circuitry, connected to leads which are epicardially or intracardially positioned on the heart.
摘要翻译：用于防止冠状动脉斑块积聚的方法和装置包括提供电场产生装置，并且在冠状动脉中产生电场以防止冠状动脉中的斑块积聚。该方法还包括感测心脏节律并在心脏中去极化波之后产生电场。电场由电路产生，在一个实施例中，植入电路连接到心外膜或心内置于心脏上的引线。

92. 发明授权

US07630755B2 Syncope logbook and method of using same 有权
标题翻译：晕厥日志及其使用方法
公开(公告)号：US07630755B2
公开(公告)日：2009-12-08
申请号：US11121450
申请日：2005-05-04
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Avram Scheiner
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Avram Scheiner
IPC分类号： A61B5/04 , A61B5/02
CPC分类号： A61B5/02028 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/02405 , A61B5/0402 , A61B5/0476 , A61B5/11 , A61B5/1116 , A61B5/145 , A61B5/14532 , A61B5/14546 , A61N1/362 , A61N1/37247 , G06F19/00 , G06F19/3418 , G06F19/3481 , G16H40/63
摘要： Method and systems are directed to acquiring and organizing information associated with at least one syncope event. A syncope event may be a suspected syncope event, a verified syncope event or a syncope event that is suspected and verified. Automated processes are used to collect information associated with at least one syncope event and organize the information as a syncope log entry. At least one of acquiring the information and organizing the information is performed at least in part implantably.
摘要翻译：方法和系统旨在获取和组织与至少一个晕厥事件相关联的信息。晕厥事件可能是疑似晕厥事件，经过验证的晕厥事件或怀疑和验证的晕厥事件。自动进程用于收集与至少一个晕厥事件相关的信息，并将该信息组织为晕厥日志条目。至少部分地可植入地执行获取信息和组织信息中的至少一个。

93. 发明申请

US20090299159A1 SYSTEM AND METHOD FOR MONITORING AUTONOMIC BALANCE AND PHYSICAL ACTIVITY 有权
标题翻译：用于监测自动平衡和物理活动的系统和方法
公开(公告)号：US20090299159A1
公开(公告)日：2009-12-03
申请号：US12538553
申请日：2009-08-10
申请人： Avram Scheiner , Donald Hopper , Gerrard M. Carlson
发明人： Avram Scheiner , Donald Hopper , Gerrard M. Carlson
IPC分类号： A61B5/0205
CPC分类号： A61B5/4035 , A61B5/029 , A61B5/0472 , A61N1/36585 , G06F19/00
摘要： An implantable device monitors the balance between sympathetic tone and parasympathetic tone as a function of an activity level. Cardio-neurological healthy users exhibit a generally sympathetic tone in conjunction with heavy activity level and a generally parasympathetic tone in conjunction with periods of low activity level. Deviations from expected results are associated with a health problem. Measured conditions are stored and available for subsequent reporting to a remote programmer. Therapy delivered by an implantable device is determined as a function of the relationship between autonomic balance and activity level.
摘要翻译：可植入装置监测交感神经张力和副交感神经紧张度之间的平衡，作为活动水平的函数。心脏神经系统健康用户表现出与大量活动水平和大体上副交感神经紧张以及低活动水平结合的共同心情。与预期结果的偏差与健康问题有关。测量条件存储并可用于后续报告给远程程序员。由植入式装置提供的治疗作为自主平衡与活动水平之间关系的函数确定。

94. 发明申请

US20090275996A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 审中-公开
标题翻译：用于放置用于电刺激神经组织的医用引线的技术
公开(公告)号：US20090275996A1
公开(公告)日：2009-11-05
申请号：US12433770
申请日：2009-04-30
申请人： John E. Burnes , Eduardo N. Warman , Matthew D. Bonner , Avram Scheiner , Shailesh Kumar V. Musley
发明人： John E. Burnes , Eduardo N. Warman , Matthew D. Bonner , Avram Scheiner , Shailesh Kumar V. Musley
IPC分类号： A61N1/36
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.
摘要翻译：本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。

95. 发明申请

US20090275956A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 有权
公开(公告)号：US20090275956A1
公开(公告)日：2009-11-05
申请号：US12433766
申请日：2009-04-30
申请人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
发明人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
IPC分类号： A61B17/00
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

96. 发明授权

US07392090B2 Data logging system for implantable medical device 有权
标题翻译：可植入医疗器械的数据记录系统
公开(公告)号：US07392090B2
公开(公告)日：2008-06-24
申请号：US10672315
申请日：2003-09-26
申请人： Robert J. Sweeney , Avram Scheiner , Ronald W. Heil, Jr.
发明人： Robert J. Sweeney , Avram Scheiner , Ronald W. Heil, Jr.
IPC分类号： A61N1/00
CPC分类号： A61B5/0031 , A61N1/30 , A61N1/3621
摘要： A data logging system and method in which an implantable medical device transmits logged data to an external data logging device with low energy potential signals. The implantable device generates potential signals modulated with digitally encoded data by operating a current source to cause corresponding electrical potentials that can be sensed at the skin surface by the external data logging device. The data logging device then demodulates the sensed potentials to derive the digital data and stores the data in a data logging storage medium.
摘要翻译：一种数据记录系统和方法，其中可植入医疗设备将记录的数据发送到具有低能量电位信号的外部数据记录装置。可植入装置通过操作电流源产生用数字编码数据调制的电位信号，以引起可由外部数据记录装置在皮肤表面感测到的对应电位。数据记录装置然后解调所感测的电位以导出数字数据并将数据存储在数据记录存储介质中。

97. 发明授权

US07328067B2 Cardiac rhythm management system and method 有权
公开(公告)号：US07328067B2
公开(公告)日：2008-02-05
申请号：US10858580
申请日：2004-06-02
申请人： Qingsheng Zhu , Avram Scheiner
发明人： Qingsheng Zhu , Avram Scheiner
IPC分类号： A61N1/00
CPC分类号： A61N1/3712
摘要： A system and method for cardiac rhythm management, which includes an electrode system having at least one electrode and control circuitry coupled to the electrode system from which a first cardiac signal is sensed. The control circuitry includes a pulse circuit to produce electrical pulses at a first value to be delivered to the electrode system in a first cardiac region. At least one cardiac signal is sensed from a second cardiac region, where the cardiac signal includes indications of cardiac depolarizations from the second cardiac region which occurs in direct reaction to the electrical pulses delivered to the first cardiac region. The first value of the electrical pulses are then modified by a pulse adjustment circuit when a cardiac depolarization which occurs in direct reaction to the electrical pulse delivered to the first cardiac region is detected from the second cardiac region.

98. 发明申请

US20070225786A1 LEFT VENTRICULAR LEAD SHAPES 有权
标题翻译：左心室导线形状
公开(公告)号：US20070225786A1
公开(公告)日：2007-09-27
申请号：US11277326
申请日：2006-03-23
申请人： Mark Bly , Brian Soltis , Bruce Tockman , Avram Scheiner
发明人： Mark Bly , Brian Soltis , Bruce Tockman , Avram Scheiner
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A lead for sensing and pacing a left ventricle of the heart includes a lead body having a proximal portion and a distal portion, a lumen extending through the lead body, a conductor extending through the lead body from the proximal end to the distal end and an electrode disposed on the distal portion of the lead body and electrically coupled to the conductor. A distal tip of the lead body is continuously deflectable upon advancement and withdrawal of a stylet through the lumen at the distal portion to access a selected branch of the coronary sinus. The distal tip of the lead body may be offset before or after continuously deflecting the distal tip.
摘要翻译：用于感测和起搏心脏左心室的引线包括具有近端部分和远端部分的引线体，延伸穿过引线主体的内腔，从近端延伸穿过引线主体到远端的导体，以及电极，其设置在引线体的远端部分上并电耦合到导体。引导体的远侧末端在通过远端部分的内腔前进和取出探针时可连续偏转，以进入冠状窦的选定分支。引线体的远端可以在连续偏转远端之前或之后偏移。

99. 发明申请

US20070123965A1 Medical electrical lead employing load bearing sleeve 失效
标题翻译：医用电线使用承载套
公开(公告)号：US20070123965A1
公开(公告)日：2007-05-31
申请号：US11643224
申请日：2006-12-21
申请人： Randy Westlund , Mohan Krishnan , Avram Scheiner
发明人： Randy Westlund , Mohan Krishnan , Avram Scheiner
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0578 , A61N2001/0585
摘要： A medical electrical lead employs a load bearing sleeve arrangement. A medical electrical lead includes an outer sleeve, having proximal and distal ends, and is formed of a first material. At least one electrical conductor is situated within the outer sleeve and extends between the proximal and distal ends of the outer sleeve. At least one electrode is electrically coupled to the electrical conductor. A load bearing sleeve extends between the proximal and distal ends of the outer sleeve. The load bearing sleeve is formed of a second material different from the first material. The load bearing sleeve offers resistance to axial loading forces applied to the lead. The load bearing sleeve can be coextensive with the outer sleeve or extend along at least the majority of the length of the outer sleeve.
摘要翻译：医用电线使用承载套筒装置。医用电线包括具有近端和远端的外套，并由第一材料形成。至少一个电导体位于外套筒内并且在外套筒的近端和远端之间延伸。至少一个电极电耦合到电导体。承载套筒在外套筒的近端和远端之间延伸。承载套筒由不同于第一材料的第二材料形成。承载套筒提供抵抗施加到引线的轴向载荷力。承载套筒可以与外套筒共同延伸或者沿外套筒的至少大部分长度延伸。

100. 发明授权

US07201733B2 Drug delivery system for implantable cardiac device 失效
标题翻译：用于植入式心脏装置的药物递送系统
公开(公告)号：US07201733B2
公开(公告)日：2007-04-10
申请号：US09999260
申请日：2001-11-30
申请人： Avram Scheiner , Mark Herner , Ronald W. Heil, Jr. , Steven D. Girouard
发明人： Avram Scheiner , Mark Herner , Ronald W. Heil, Jr. , Steven D. Girouard
IPC分类号： A61M31/00
CPC分类号： A61N1/30 , A61N1/3621 , Y10S128/12 , Y10S128/13
摘要： A drug delivery system incorporated into a cardiac device for delivering a dose of a drug to a patient upon detection of a particular medical condition. The cardiac device may be, for example, an implantable cardioverter/defibrillator, cardiac pacemaker, or combination device that communicates via a radio frequency link with a drug delivery device. The drug delivery device is preferably an electrically modulated transdermal drug delivery device for delivering the drug transdermally in accordance with a signal received from the cardiac device.
摘要翻译：一种药物递送系统，其结合到心脏装置中，用于在检测到特定医疗状况时将药物的剂量递送给患者。心脏装置可以是例如通过射频链路与药物递送装置进行通信的可植入式心律转复器/除颤器，心脏起搏器或组合装置。药物递送装置优选是经电调制的透皮药物递送装置，用于根据从心脏装置接收的信号透皮地递送药物。

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