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91. 发明申请

US20100137937A1 Modulation and Analysis of Cerebral Perfusion In Epilepsy and Other Neurological Disorders 有权
标题翻译：癫痫和其他神经系统疾病脑灌注调制与分析
公开(公告)号：US20100137937A1
公开(公告)日：2010-06-03
申请号：US12700692
申请日：2010-02-04
申请人： Michael Sasha John , Benjamin D. Pless , Brett Wingeier
发明人： Michael Sasha John , Benjamin D. Pless , Brett Wingeier
IPC分类号： A61N1/36 , A61B5/1459
CPC分类号： A61N1/36139 , A61B5/0031 , A61B5/02 , A61B5/0476 , A61B5/14553 , A61B5/1459 , A61B5/4094 , A61B5/6868 , A61B5/7217 , A61B8/06 , A61B8/12 , A61B8/488 , A61F7/00 , A61F7/12 , A61N1/36057 , A61N1/36064 , A61N1/36082 , A61N1/36135 , A61N2/006 , A61N2/02 , A61N5/0622 , A61N7/00 , A61N2007/0043
摘要： A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.
摘要翻译：一种包括能够调节脑血流以治疗癫痫和其他神经障碍的可植入神经刺激器装置的系统。在一个实施方案中，系统能够响应于测量和其他观察到的条件而调节脑血流量（也称为脑灌注）。根据临床要求的根据本发明的系统和方法可以增加或减少灌注。

92. 发明申请

US20100087745A1 Baseline processing for a cardiac event detection system 有权
标题翻译：心脏事件检测系统的基线处理
公开(公告)号：US20100087745A1
公开(公告)日：2010-04-08
申请号：US12585861
申请日：2009-09-28
申请人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson , Bruce Hopenfeld , Michael Sasha John
发明人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson , Bruce Hopenfeld , Michael Sasha John
IPC分类号： A61B5/0452
CPC分类号： A61B5/0456 , A61B5/0006 , A61B5/0031 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/7465 , A61B2560/0209 , A61N1/3627 , A61N1/3702
摘要： A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal and a patient alarm means is further provided and electrically coupled to the electrical signal processor. The electrical signal is acquired in the form of electrogram segments, which are categorized according to heart rate, ST segment shift and type heart rhythm (normal or abnormal). Baseline electrogram segments are tracked over time.
摘要翻译：提供了一种用于检测在人类患者中发生的心脏事件的系统。系统中包括至少两个电极，以从患者的心脏获得电信号。电信号处理器电耦合到电极以处理电信号，并且还提供患者报警装置并电耦合到电信号处理器。电信号是以心律，ST段移位和心律（正常或异常）分为心电图段的形式获得的。基线电描绘片段随时间跟踪。

93. 发明申请

US20080288405A1 Systems and Methods for Automatic and Transparent Client Authentication and Online Transaction Verification 审中-公开
标题翻译：自动和透明客户端验证和在线事务验证的系统和方法
公开(公告)号：US20080288405A1
公开(公告)日：2008-11-20
申请号：US12124144
申请日：2008-05-20
申请人： Michael Sasha John
发明人： Michael Sasha John
IPC分类号： G06Q40/00
CPC分类号： G06Q30/06 , G06Q20/40
摘要： Systems and methods are described for providing fraud deterrents, detection and prevention during e-commerce, e-transactions, digital rights management and access control. Fraud deterrent levels may be automatically selected by a requesting transaction approval entity server (and can be related to level of risk, or security, related to fraud) or may be selected by a consumer. These deterrent levels can determine the manner in which the transaction occurs as well as the types of information that must be provided and validated for successful approval of the transaction. The client can associate their credit card with a specific device, an e-identity, such as an instant messaging identity, and the e-identity is contacted as a part of finalizing a payment transaction so that a client response of ‘approve’ or ‘reject’ can be obtained. The anti-fraud technology also provides for management and storage of historical transaction information. Entity-to-client communication occurs according to merchant permission parameters which are defined by the client and which enable messages sent by the entity to be automatically allowed, rejected, and managed in other ways as well.
摘要翻译：描述了用于在电子商务，电子交易，数字版权管理和访问控制期间提供欺诈威慑，检测和预防的系统和方法。欺诈威慑级别可以由请求的交易批准实体服务器自动选择（并且可以与涉及欺诈的风险级别或安全性相关），或者可由消费者选择。这些威慑级别可以确定交易发生的方式以及必须提供和验证以获得成功批准交易的信息类型。客户端可以将其信用卡与特定设备，电子身份（例如即时消息身份）相关联，并将电子身份与作为完成付款交易的一部分进行联系，以便客户对“批准”或“ 拒绝“。反诈骗技术还提供历史交易信息的管理和存储。实体到客户端通信根据由客户端定义的商家许可参数发生，并且使得实体发送的消息能够以其他方式被自动允许，拒绝和管理。

94. 发明申请

US20080288023A1 Medical treatment using patient states, patient alerts, and hierarchical algorithms 审中-公开
标题翻译：使用患者状态，患者警报和分级算法进行治疗
公开(公告)号：US20080288023A1
公开(公告)日：2008-11-20
申请号：US11309605
申请日：2006-08-30
申请人： Michael Sasha John
发明人： Michael Sasha John
IPC分类号： A61N1/36
CPC分类号： A61N1/37247
摘要： Systems and methods are described for adjusting the operation of implantable stimulation devices used to provide medical treatment. Several hierarchical algorithms are described which operate according to conditional strategies. In one such strategy semi-automatic therapy adjustment occurs by automatically issuing patient alert messages when selected operations are to occur, and using a patient's response to the alert message in order to adjust therapy, as long as this is provided within a selected time limit. Another strategy only implements complex operations when these are indicated by prior operations. The invention serves to reduce the risk of adaptation by the patient and the provision of therapy operations that are either not desired or warranted, in order to decrease the depletion of battery power and/or drug reserves and increase patient benefit. Methods are also described for resolving data conflicts which may occur when adaptively delivery therapy.
摘要翻译：描述了用于调节用于提供医疗处理的可植入刺激装置的操作的系统和方法。描述了根据条件策略进行操作的几种分层算法。在一种这样的策略中，半自动治疗调整是通过在选择的操作发生时自动发出患者警报消息，并且使用病人对警报消息的响应来调整治疗，只要这在选定的时间限制内提供即可。另一个策略只有在以前的操作指示这些操作时才会执行复杂的操作。本发明用于降低患者的适应风险和提供不期望或保证的治疗操作，以便减少电池功率和/或药物储备的消耗并增加患者益处。还描述了解决自适应递送治疗时可能发生的数据冲突的方法。

95. 发明申请

US20080264955A1 Adaptive Drinkware. 审中-公开
标题翻译：自适应饮料
公开(公告)号：US20080264955A1
公开(公告)日：2008-10-30
申请号：US12108370
申请日：2008-04-23
申请人： David Joshua John , Michael Sasha John
发明人： David Joshua John , Michael Sasha John
IPC分类号： A47G19/22 , B65D25/24
CPC分类号： A47G19/2227 , A47G19/2261 , A47G2019/2238 , A47G2019/2244
摘要： Vessels systems are disclosed which change their shape as a function of their environment. This can include adopting to the amount of fluid held by the drinkware or the surface upon which it resides. The drinkware is therefore designed well for reside on both flat and irregular surfaces. As mass is added or removed from a vessel portion, a support system provides features such as measure, signaling, increased stability, and associated entertainment value corresponding to such features. The support system can serve to lower the center of gravity of a vessel when it is relatively full compared to when it is relatively empty.
摘要翻译：公开了根据其环境改变其形状的船舶系统。这可以包括采用由饮料器皿或其所在的表面保持的液体的量。因此，这种饮品可以很好地设计在两个平面和不规则的表面上。当从容器部分添加或移除质量时，支撑系统提供诸如度量，信令，增加的稳定性和与这些特征相对应的相关娱乐值的特征。当支撑系统相对于相对空的时候，其支撑系统可以用于降低容器的重心。

96. 发明申请

US20080167701A1 ADAPTIVE CONDUCTIVE LEAD SYSTEMS 失效
标题翻译：自适应导电系统
公开(公告)号：US20080167701A1
公开(公告)日：2008-07-10
申请号：US11970781
申请日：2008-01-08
申请人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
发明人： MICHAEL SASHA JOHN , DAVID R. FISCHELL
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/086
摘要： The invention describes fluid-based lead systems. The fluid-based leads may be used for sensing from, and stimulating of, human tissue. The fluid-based leads can be used to transfer signals between two locations. The fluid-based leads offer advantages when communicating signals along their length since the leads may be safely used in magnetic environments and offer increased elastic characteristics which are less prone to breakage. The leads can be used externally or with implantable devices, such as those used to monitor, and deliver therapy during the treatment of medical disorders such as cardiac and neurological disorders.
摘要翻译：本发明描述了基于流体的铅系统。基于流体的引线可用于感测和刺激人体组织。基于流体的引线可用于在两个位置之间传输信号。当基于流体的导线沿着它们的长度传递信号时，提供了优点，因为引线可以安全地用于磁性环境中并提供增加的弹性特性，这些特性不容易断裂。引线可以在外部使用，也可以使用可植入的装置，例如用于监测的药物，以及治疗诸如心脏和神经障碍等医学疾病期间的治疗。

97. 发明授权

US06463328B1 Adaptive brain stimulation method and system 有权
标题翻译：自适应脑刺激方法和系统
公开(公告)号：US06463328B1
公开(公告)日：2002-10-08
申请号：US09480052
申请日：2000-01-10
申请人： Michael Sasha John
发明人： Michael Sasha John
IPC分类号： A61N136
CPC分类号： A61N1/36135 , A61N1/36082 , G06F19/00
摘要： Adaptive brain stimulation systems and methods aids in the rehabilitation of patients from traumatic brain injury, coma, movement disorder, or other brain dysfunction. After a direct brain stimulator is implanted in a brain region of a patient, the patient is stimulated according to a set of stimulation parameters. A present state is measured and compared to a reference state by statistical and medically relevant criteria. The subsequent program of stimulation is dependent upon the outcome of the comparison. An adaptive brain stimulation and reinforcement system and method is also described in which a second area of the brain is stimulated when stimulation of the first brain area produces a desired effect, thereby reinforcing the prior response of the brain.
摘要翻译：自适应脑刺激系统和方法有助于患者从创伤性脑损伤，昏迷，运动障碍或其他脑功能障碍康复。将直接脑刺激器植入患者的脑区域后，根据一组刺激参数刺激患者。通过统计学和医学上相关的标准测量现状并将其与参考状态进行比较。随后的刺激计划取决于比较的结果。还描述了一种适应性脑刺激和增强系统和方法，其中当第一脑区域的刺激产生期望的效果时刺激脑的第二区域，从而加强脑的先前反应。

98. 发明授权

US11964156B1 Transcutaneous electrical stimulation treatment of migraines and headaches 有权
公开(公告)号：US11964156B1
公开(公告)日：2024-04-23
申请号：US18474992
申请日：2023-09-26
申请人： Michael Sasha John
发明人： Michael Sasha John
IPC分类号： A61N1/36 , A61N1/372 , A61M5/142 , A61M5/172 , A61N1/04 , A61N1/05
CPC分类号： A61N1/36178 , A61N1/36064 , A61N1/36082 , A61N1/37235 , A61M5/14276 , A61M5/172 , A61M5/1723 , A61N1/0456 , A61N1/0529 , A61N1/36071 , A61N1/36114
摘要： A method for treating an unwanted symptom experienced by a person due to migraines or headaches. A set of transcutaneous electrodes are placed on a person's body. A computer processor controls an electrical signal generator in accordance with a stimulation protocol. An electrical signal generator generates a modulated stimulation signal as a high frequency signal in a high frequency range within the range of 80 Hz-200 Hz. The high frequency is adjusted to rove between a first roving frequency and a second roving frequency within the high frequency range of the high frequency carrier signal according to the stimulation protocol for transmitting the high frequency carrier signal to the set of two transcutaneous electrodes for treatment of the person.

99. 发明公开

US20240112231A1 Systems and Methods for Automatic and Transparent Client Authentication and Online Transaction Verfication 审中-公开
公开(公告)号：US20240112231A1
公开(公告)日：2024-04-04
申请号：US18539181
申请日：2023-12-13
申请人： Michael Sasha John
发明人： Michael Sasha John
IPC分类号： G06Q30/06 , G06Q20/40
CPC分类号： G06Q30/06 , G06Q20/40
摘要： Systems and methods are described for providing fraud deterrents, detection and prevention during e-commerce, e-transactions, digital rights management and access control. Fraud deterrent levels may be automatically selected by a requesting transaction approval entity server (and can be related to level of risk, or security, related to fraud) or may be selected by a consumer. These deterrent levels can determine the manner in which the transaction occurs as well as the types of information that must be provided and validated for successful approval of the transaction. The client can associate their credit card with a specific device, an e-identity, such as an instant messaging identity, and the e-identity is contacted as a part of finalizing a payment transaction so that a client response of ‘approve’ or ‘reject’ can be obtained. The anti-fraud technology also provides for management and storage of historical transaction information. Entity-to-client communication occurs according to merchant permission parameters which are defined by the client and which enable messages sent by the entity to be automatically allowed, rejected, and managed in other ways as well.

100. 发明授权

US11907946B2 Fraud deterrence for secure transactions 有权
公开(公告)号：US11907946B2
公开(公告)日：2024-02-20
申请号：US18095237
申请日：2023-01-10
申请人： Michael Sasha John
发明人： Michael Sasha John
IPC分类号： G06Q20/40 , G06F21/32 , G06F21/35 , G06F21/60 , G06F21/62 , G06Q20/12 , G06Q20/38 , G06Q20/42 , G06Q30/06 , G06Q30/0601 , G06Q40/00
CPC分类号： G06Q20/40 , G06F21/32 , G06F21/35 , G06F21/606 , G06F21/6263 , G06Q20/123 , G06Q20/382 , G06Q20/405 , G06Q20/409 , G06Q20/4012 , G06Q20/4016 , G06Q20/40145 , G06Q20/425 , G06Q30/06 , G06Q30/0601 , G06Q30/0613 , G06Q40/00
摘要： An illustrative fraud deterrent method includes presenting an identity verification option for a first website displayed in a web-browser, the option including offering a login to a third-party website, unrelated to the first website. The method further includes receiving login information for a first user account on the third-party website and verifying the login information through a verification service associated with the third-party website, to verify that the login information is valid for the first user account, identified by the login information. The method additionally includes verifying an identity at the first website, responsive to the verification.

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