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91. 发明授权

US08324392B2 Solid form of 4-[[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino]furan-2(5H)-one 失效
标题翻译：固体形式的4 - [[（6-氯吡啶-3-基）甲基]（2,2-二氟乙基）氨基]呋喃-2（5H） - 酮
公开(公告)号：US08324392B2
公开(公告)日：2012-12-04
申请号：US12910201
申请日：2010-10-22
申请人： Britta Olenik , Robert Velten , Peter Jeschke , Norbert Lui , Christian Funke , Wolfgang Wirth
发明人： Britta Olenik , Robert Velten , Peter Jeschke , Norbert Lui , Christian Funke , Wolfgang Wirth
IPC分类号： C07D213/62 , A61K31/44
CPC分类号： C07D405/12
摘要： The present invention relates to a novel solid form of 4-[[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino]furan-2(5H)-one, to processes for its preparation and to its use in agrochemical preparations.
摘要翻译：本发明涉及4 - [[（6-氯吡啶-3-基）甲基]（2,2-二氟乙基）氨基]呋喃-2（5H） - 酮的新固体形式，其制备方法和其用于农药制剂。

92. 发明授权

US08323948B2 Asparaginases and uses thereof 有权
标题翻译：天冬酰胺酶及其用途
公开(公告)号：US08323948B2
公开(公告)日：2012-12-04
申请号：US13137597
申请日：2011-08-29
申请人： Jan Metske Van Der Laan , Mark Cristiaan Stor , Ilse De Lange , Lisette Mohrmann
发明人： Jan Metske Van Der Laan , Mark Cristiaan Stor , Ilse De Lange , Lisette Mohrmann
IPC分类号： C12N9/00 , C12N9/78 , C12N1/20 , C12N15/00
CPC分类号： C12N9/82 , A23L5/25 , A23L29/06 , C12Y305/01001
摘要： The present invention relates to an asparaginase having the width of the pH activity profile which is at least 3.5. Furthermore the invention relates to newly identified asparaginase polypeptide according to any one of SEQ ID NO: 2 or SEQ ID NO: 4 and to variants thereof and to polynucleotide sequences that encode such novel asparaginase variants. Furthermore the invention relates to the use of these novel asparaginase variants in industrial processes.
摘要翻译：本发明涉及具有至少3.5的pH活性分布宽度的天冬酰胺酶。此外，本发明涉及根据SEQ ID NO：2或SEQ ID NO：4中任一项的新鉴定的天冬酰胺酶多肽及其变体，以及编码这种新型天冬酰胺酶变体的多核苷酸序列。此外，本发明涉及这些新型天冬酰胺酶变体在工业过程中的用途。

93. 发明授权

US08318637B2 Herbicide/azole combination 有权
标题翻译：除草剂/唑类组合
公开(公告)号：US08318637B2
公开(公告)日：2012-11-27
申请号：US12743738
申请日：2008-11-15
申请人： Arne Brink , Rolf Pontzen , Stefan Dutzmann
发明人： Arne Brink , Rolf Pontzen , Stefan Dutzmann
IPC分类号： A01N43/64
CPC分类号： A01N43/50 , A01N47/36 , A01N47/38 , A01N25/32 , A01N43/56 , A01N43/653 , A01N2300/00
摘要： Herbicide/azole combination comprising components (A) and (B) having improved effects, where (A)is one or more herbicidally active compounds from the group of the ALS inhibitors, and (B)is one or more agrochemically active azole compounds, preferably from the group of the triazoles, pyrazoles and triazolinethiones.
摘要翻译：包含具有改善效果的组分（A）和（B）的除草剂/唑组合，其中（A）是来自ALS抑制剂组的一种或多种除草活性化合物，和（B）是一种或多种农业化学活性唑化合物，优选来自三唑，吡唑和三唑啉硫酮的一组。

94. 发明授权

US08304371B2 Insecticidal arylpyrrolines 有权
标题翻译：杀虫芳基吡咯啉
公开(公告)号：US08304371B2
公开(公告)日：2012-11-06
申请号：US12863980
申请日：2009-01-29
申请人： Ulrich Görgens , Yasushi Yoneta , Tetsuya Murata , Jun Mihara , Kei Domon , Eiichi Shimojo , Katsuhiko Shibuya , Teruyuki Ichihara
发明人： Ulrich Görgens , Yasushi Yoneta , Tetsuya Murata , Jun Mihara , Kei Domon , Eiichi Shimojo , Katsuhiko Shibuya , Teruyuki Ichihara
IPC分类号： A01C1/06 , A01N43/653 , A01N43/36 , A01N43/56 , A01N43/50 , A01N43/647 , A01N43/713 , A01N43/40 , A01P7/04
CPC分类号： A01N43/36 , A01N43/50 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , C07D207/20 , C07D249/10 , C07D403/10 , C07F7/081 , C07F7/0812
摘要： The invention relates to novel arylpyrroline compounds of formula (I) which having excellent insecticidal activity and which can thus be used as an insecticide is provided.
摘要翻译：本发明涉及具有优异杀虫活性并因此可用作杀虫剂的式（I）的新型芳基吡咯啉化合物。

95. 发明授权

US08298989B2 Active ingredient combinations with insecticidal properties 有权
标题翻译：活性成分组合具有杀虫性
公开(公告)号：US08298989B2
公开(公告)日：2012-10-30
申请号：US12295074
申请日：2007-03-28
申请人： Christian Funke , Rüdiger Fischer , Reiner Fischer , Wolfgang Thielert , Anton Kraus , Heike Hungenberg
发明人： Christian Funke , Rüdiger Fischer , Reiner Fischer , Wolfgang Thielert , Anton Kraus , Heike Hungenberg
IPC分类号： A01N25/00 , A01N43/40 , A01N25/18
CPC分类号： A01N43/56 , A01N2300/00
摘要： Agrochemical compositions comprising at least one active compound from the class of the anthranilamides and at least one further active compound selected from the group consisting of insecticides, fungicides, and/or acaricides have excellent synergistic activity.
摘要翻译：包含至少一种来自邻氨基苯甲酰胺的活性化合物和至少一种选自杀虫剂，杀真菌剂和/或杀螨剂的其它活性化合物的农药组合物具有优异的协同作用。

96. 发明授权

US08292786B1 Wireless head set for lingual manipulation of an object, and method for moving a cursor on a display 有权
标题翻译：用于对物体进行语言操作的无线头部，以及用于在显示器上移动光标的方法
公开(公告)号：US08292786B1
公开(公告)日：2012-10-23
申请号：US13315885
申请日：2011-12-09
申请人： Youhanna Al-Tawil
发明人： Youhanna Al-Tawil
IPC分类号： A63B71/00
CPC分类号： A61F4/00 , G05G1/52 , G06F3/011 , G06F3/0481
摘要： A head set is provided. The head set is beneficial for assisting an individual who is significantly impaired in the use of his or her upper extremities. The system enables this individual to move a cursor on a display of a computer or other processing device using lingual musculature. The head set includes a head piece. The head piece supports an articulating arm. The articulating arm supports a mouthpiece at a distal end. The mouthpiece has a plurality of cells embedded therein. The cells are configured to receive pressure applied by the tongue of the user. Movement of the tongue over and against the cells causes the cursor to be moved on the display. A method for moving a cursor on a display using a mouthpiece controlled through lingual movement is also provided. In addition, a method of typing characters on a virtual keyboard using lingual musculature is offered.
摘要翻译：提供头套。头套有助于协助一名在使用上肢受到严重损害的个人。该系统使得该个人能够使用语言肌肉组织在计算机或其他处理装置的显示器上移动光标。头套包括头部件。头部支撑铰接臂。铰接臂支撑在远端的接口。接口具有嵌入其中的多个单元。细胞被配置为接收由使用者的舌头施加的压力。舌头与细胞的移动导致光标在显示器上移动。还提供了一种通过使用通过舌头运动控制的接口管来在显示器上移动光标的方法。此外，还提供了使用语言肌肉组合在虚拟键盘上输入字符的方法。

97. 发明授权

US08288316B2 N-(1,2,5-oxadiazol-3-yl)benzamides and their use as herbicides 有权
标题翻译： N-（1,2,5-恶二唑-3-基）苯甲酰胺及其作为除草剂的用途
公开(公告)号：US08288316B2
公开(公告)日：2012-10-16
申请号：US12888696
申请日：2010-09-23
申请人： Arnim Köhn , Jörg Tiebes , Andreas Almsick , Hartmut Ahrens , Ines Heinemann , Ralf Braun , Monika H Schmitt , Lothar Willms , Dieter Feucht , Christopher Hugh Rosinger , Isolde Häuser-Hahn , Mark Drewes , Simon Dörner-Rieping , Jan Dittgen , Martin Adamczewski
发明人： Arnim Köhn , Jörg Tiebes , Andreas Almsick , Hartmut Ahrens , Ines Heinemann , Ralf Braun , Monika H Schmitt , Lothar Willms , Dieter Feucht , Christopher Hugh Rosinger , Isolde Häuser-Hahn , Mark Drewes , Simon Dörner-Rieping , Jan Dittgen , Martin Adamczewski
IPC分类号： A01N25/32 , A01N43/828 , A01N43/54 , A01N43/40 , A01P3/00 , A01P7/02 , A01P13/00 , C07D271/04 , C07D403/12 , C07D401/04
CPC分类号： C07D271/08 , C07D413/04 , C07D413/12 , C07D413/14
摘要： There are described N-(1,2,5-oxadiazol-3-yl)benzamides of the general formula (I) as herbicides. In this formula (I), X, Y, Z and R are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen.
摘要翻译：描述了通式（I）的N-（1,2,5-恶二唑-3-基）苯甲酰胺作为除草剂。在该式（I）中，X，Y，Z和R是诸如氢，有机基团如烷基和其它基团如卤素的基团。

98. 发明授权

US08272652B2 Suspension for vehicle 有权
标题翻译：车辆暂停
公开(公告)号：US08272652B2
公开(公告)日：2012-09-25
申请号：US12979022
申请日：2010-12-27
申请人： Frank Majerik
发明人： Frank Majerik
IPC分类号： B60G9/02 , B60G21/055 , B60G3/12
CPC分类号： B60G7/001 , B60G9/022 , B60G11/003 , B60G2200/341 , B60G2206/11
摘要： A suspension for a rear or a front portion of a chassis for vehicles in which a pair of longitudinal stabilizer assemblies and an anti-sway stabilizer each use a same type of a stabilizer bar, with the longitudinal stabilizer assemblies pivotably connected on opposing sides of the chassis and the anti-sway stabilizer pivotably connected in transverse relation proximate an end of the chassis. The longitudinal stabilizer assemblies and the anti-sway stabilizer each include a portion of a saddle that extends around the axle and rigidly connects to the axle. A shock absorber connects between the saddle and the chassis.
摘要翻译：用于车辆的底盘的后部或前部的悬架，其中一对纵向稳定器组件和防摇摆稳定器各自使用相同类型的稳定杆，纵向稳定器组件可枢转地连接在底盘和防摇摆稳定器可靠地靠近底盘的端部以横向关系枢转地连接。纵向稳定器组件和防摇摆稳定器各自包括鞍座的围绕轴延伸并且刚性地连接到车轴的部分。减震器连接在鞍座和底盘之间。

99. 发明授权

US08252579B2 Evolved micro-organisms for the production of 1,2-propanediol 有权
标题翻译：用于生产1,2-丙二醇的进化微生物
公开(公告)号：US08252579B2
公开(公告)日：2012-08-28
申请号：US10585040
申请日：2005-01-12
申请人： Isabelle Meynial-Salles , Benjamin Gonzalez , Philippe Soucaille
发明人： Isabelle Meynial-Salles , Benjamin Gonzalez , Philippe Soucaille
IPC分类号： C12Q1/68 , C12P7/02 , C12N1/20 , C12N9/00 , C12N9/02 , C12N9/04 , C12N15/00 , C07H21/04
CPC分类号： C12P7/18 , C12N9/0051 , C12N15/01 , C12P7/28
摘要： The present invention concerns a new method of preparation of a strain of evolved micro-organisms for the production of 1,2-propanediol by the metabolism of a simple carbon source, which method comprises the growth under selection pressure in an appropriate growth medium containing a simple carbon source of an initial bacterial strain that has undergone the deletion of the gene tpiA and the deletion of at least one gene involved in the conversion of methylglyoxal (propanal) into lactate, in order to cause, in said initial strain, the evolution of one or more genes involved in the biosynthesis pathway from DHAP to methylglyoxal and then to 1,2-propanediol towards evolved genes that possess an improved “1,2-propanediol synthase activity”, the resulting strain or strains of evolved micro-organisms possessing an improved “1,2-propanediol synthase activity” then being selected and isolated.The invention also concerns the initial micro-organisms and the evolved micro-organisms thus obtained, and a method for the preparation of 1,2-propanediol and possibly acetone by culture of said evolved micro-organisms.
摘要翻译：本发明涉及通过简单碳源的代谢来制备用于生产1,2-丙二醇的进化微生物菌株的新方法，该方法包括在选择压力下在合适的生长培养基中生长，所述合适的生长培养基含有已经经历基因tpiA缺失的初始细菌菌株的简单碳源和涉及将甲基乙二醛（丙醛）转化成乳酸盐的至少一个基因的缺失，以便在所述初始菌株中引起涉及从DHAP到甲基乙二醛然后到1,2-丙二醇的生物合成途径中的一个或多个基因转化为具有改进的“1,2-丙二醇合酶活性”的进化基因，所得的产生的菌株或进化微生物菌株具有然后选择和分离改进的“1,2-丙二醇合酶活性”。本发明还涉及由此获得的初始微生物和进化微生物，以及通过培养所述进化微生物制备1,2-丙二醇和可能的丙酮的方法。

100. 发明授权

US08242311B2 Process for preparing 2,2-difluoroethylamine and salts thereof proceeding from difluoroacetonitrile 有权
标题翻译：从二氟乙腈制备2,2-二氟乙胺及其盐的方法
公开(公告)号：US08242311B2
公开(公告)日：2012-08-14
申请号：US12963738
申请日：2010-12-09
申请人： Norbert Lui , Stefan Antons , Wahed Ahmed Moradi
发明人： Norbert Lui , Stefan Antons , Wahed Ahmed Moradi
IPC分类号： C07C209/48 , C07C209/62
CPC分类号： C07C233/13 , C07C209/62 , C07C231/06 , C07C211/15
摘要： The present invention relates to a process for preparing 2,2-difluoroethylamine of the formula (I) and salts thereof, for example sulphates, hydrochlorides or acetates, which proceeds from difluoroacetonitrile.
摘要翻译：本发明涉及由二氟乙腈制备的式（I）的2,2-二氟乙胺及其盐，例如硫酸盐，盐酸盐或乙酸盐的制备方法。

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