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1. 发明授权

US08808992B2 SHOC2 mutations causing noonan-like syndrome with loose anagen hair 有权
标题翻译： SHOC2突变导致了具有松散原生动物头发的无复旦综合征
公开(公告)号：US08808992B2
公开(公告)日：2014-08-19
申请号：US12775396
申请日：2010-05-06
申请人： Bruce D. Gelb , Marco Tartaglia , Len Pennacchio , Ravi Iyengar , Avi Ma'ayan
发明人： Bruce D. Gelb , Marco Tartaglia , Len Pennacchio , Ravi Iyengar , Avi Ma'ayan
IPC分类号： C12Q1/68 , C07K5/00
CPC分类号： C12Q1/6883 , C07K14/4702 , C12Q2600/156
摘要： The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is an A-to-G transition at position 4 resulting in a mutation at position 2 of SHOC2 amino acid sequence from serine to glycine. The invention also provides related sequences and kits.
摘要翻译：本发明涉及用松质毛发诊断Noonan样综合征的方法，其包括检测SHOC2基因中的突变。公开的一个具体的诊断突变是位置4处的A至G转换，导致在从丝氨酸到甘氨酸的SHOC2氨基酸序列的位置2处的突变。本发明还提供相关的序列和试剂盒。

2. 发明申请

US20080261820A1 Methods to Analyze Biological Networks 审中-公开
标题翻译：分析生物网络的方法
公开(公告)号：US20080261820A1
公开(公告)日：2008-10-23
申请号：US11997632
申请日：2006-08-01
申请人： Ravi Iyengar , Avi Ma'ayan
发明人： Ravi Iyengar , Avi Ma'ayan
IPC分类号： C40B30/02
CPC分类号： G16B40/00 , G16B5/00 , G16B20/00 , G16B45/00
摘要： The present invention relates to a family of graph-theory based methods for the analysis of intracellular signaling networks created from biomedical literature using data-mining processes or acquired through high-content experiments. The methods of the present invention can be used to identify functional dynamic modules within biological networks that can be analyzed quantitatively for input/output relationships. In particular, the present invention relates to a computer-aided method for the in-silico analysis of signaling and other cellular interaction pathways to rank drug targets, identify biomarkers, predict side effects, and classify/diagnose patients.
摘要翻译：本发明涉及一种基于图论的家族分析方法，用于分析使用数据挖掘过程或通过高含量实验获得的生物医学文献创建的细胞内信号网络。本发明的方法可以用于识别可以在输入/输出关系下定量分析的生物网络内的功能动态模块。特别地，本发明涉及计算机辅助方法，用于计算机分析信号和其他细胞相互作用途径以排列药物靶标，鉴定生物标志物，预测副作用以及分类/诊断患者。

3. 发明授权

US10552157B2 System and method to clear and rebuild dependencies 有权
公开(公告)号：US10552157B2
公开(公告)日：2020-02-04
申请号：US15208602
申请日：2016-07-12
申请人： Ravi Iyengar , Sandeep Kumar Dubey
发明人： Ravi Iyengar , Sandeep Kumar Dubey
IPC分类号： G06F9/38 , G06F9/30
摘要： A data processing method for a data processing system, comprising: initializing a value of a counter associated with a first entry to indicate a number of destinations of other entries on which the first entry depends; changing the value of the counter in a first direction in response to selecting a first one of the other entries; and changing the value of the counter in a second direction opposite the first direction in response to cancelling a second one of the other entries.

4. 发明申请

US20140281404A1 SYSTEM AND METHOD TO CLEAR AND REBUILD DEPENDENCIES 有权
标题翻译：清除和重建依赖的系统和方法
公开(公告)号：US20140281404A1
公开(公告)日：2014-09-18
申请号：US13831434
申请日：2013-03-14
申请人： Ravi Iyengar , Sandeep Kumar Dubey
发明人： Ravi Iyengar , Sandeep Kumar Dubey
IPC分类号： G06F9/30
CPC分类号： G06F9/3838 , G06F9/30145 , G06F9/30181 , G06F9/3842 , G06F9/3859
摘要： A data processing system and method of clearing and rebuilding dependencies, the data processing method including changing a counter associated with a first entry in response to selecting a second entry; comparing the counter with a threshold; and indicating that the first entry is ready to be selected in response to comparing the counter with the threshold; wherein the first entry is dependent on the second entry.
摘要翻译：一种清理和重建依赖性的数据处理系统和方法，所述数据处理方法包括响应于选择第二条目而改变与第一条目相关联的计数器; 将计数器与阈值进行比较; 并且响应于将所述计数器与所述阈值进行比较来指示所述第一条目准备好被选择; 其中所述第一条目取决于所述第二条目。

5. 发明授权

US09588770B2 Dynamic rename based register reconfiguration of a vector register file 有权
标题翻译：矢量寄存器文件的基于动态重命名的寄存器重新配置
公开(公告)号：US09588770B2
公开(公告)日：2017-03-07
申请号：US13837213
申请日：2013-03-15
申请人： Bradley Gene Burgess , Ashraf Ahmed , Ravi Iyengar
发明人： Bradley Gene Burgess , Ashraf Ahmed , Ravi Iyengar
IPC分类号： G06F9/30 , G06F9/40 , G06F9/38
CPC分类号： G06F9/30098 , G06F9/30112 , G06F9/384
摘要： Reconfiguring a register file using a rename table having a plurality of fields that indicate fracture information about a source register of an instruction for instructions which have narrow to wide dependencies.
摘要翻译：使用具有多个字段的重命名表来重新配置寄存器文件，所述多个字段指示关于具有窄到宽依赖性的指令的指令的源寄存器的断裂信息。

6. 发明申请

US20140281393A1 REORDER-BUFFER-BASED STATIC CHECKPOINTING FOR RENAME TABLE REBUILDING 有权
标题翻译：基于重构缓冲区的静态检测用于重命名表重建
公开(公告)号：US20140281393A1
公开(公告)日：2014-09-18
申请号：US13831522
申请日：2013-03-14
申请人： Ravi Iyengar , Prarthna Santhanakrishnan
发明人： Ravi Iyengar , Prarthna Santhanakrishnan
IPC分类号： G06F9/30
CPC分类号： G06F9/30098 , G06F9/384 , G06F9/3855 , G06F9/3863
摘要： Out-of-order CPUs, devices and methods diminish the time penalty from stalling the pipe to rebuild a rename table, such as due to a misprediction. A microprocessor can include a pipe that has a decoder, a dispatcher, and at least one execution unit. A rename table stores rename data, and a check-point table (“CPT”) stores rename data received from the dispatcher. A Re-Order Buffer (“ROB”) stores ROB data, and has a static mapping relationship with the CPT. If the rename table is flushed, such as due to a misprediction, the rename table is rebuilt at least in part by concurrent copying of rename data stored in the CPT, in coordination with walking the ROB.
摘要翻译：无序的CPU，设备和方法减少了管道停止的时间，从而重建重命名表，例如由于错误预测。微处理器可以包括具有解码器，调度器和至少一个执行单元的管道。重命名表存储重命名数据，并且检查点表（“CPT”）存储从分派器接收的重命名数据。重新排序缓冲区（“ROB”）存储ROB数据，与CPT具有静态映射关系。如果重命名表被刷新，例如由于错误预测，则重命名表至少部分地通过并行复制存储在CPT中的重命名数据，与步行ROB协调来重建。

7. 发明授权

US09400653B2 System and method to clear and rebuild dependencies 有权
标题翻译：清除和重建依赖关系的系统和方法
公开(公告)号：US09400653B2
公开(公告)日：2016-07-26
申请号：US13831434
申请日：2013-03-14
申请人： Ravi Iyengar , Sandeep Kumar Dubey
发明人： Ravi Iyengar , Sandeep Kumar Dubey
IPC分类号： G06F9/30 , G06F9/38 , G06F9/00
CPC分类号： G06F9/3838 , G06F9/30145 , G06F9/30181 , G06F9/3842 , G06F9/3859
摘要： A data processing system and method of clearing and rebuilding dependencies, the data processing method including changing a counter associated with a first entry in response to selecting a second entry; comparing the counter with a threshold; and indicating that the first entry is ready to be selected in response to comparing the counter with the threshold; wherein the first entry is dependent on the second entry.
摘要翻译：一种清理和重建依赖性的数据处理系统和方法，所述数据处理方法包括响应于选择第二条目而改变与第一条目相关联的计数器; 将计数器与阈值进行比较; 并且响应于将所述计数器与所述阈值进行比较来指示所述第一条目准备好被选择; 其中所述第一条目取决于所述第二条目。

8. 发明申请

US20140281414A1 REORDER-BUFFER-BASED DYNAMIC CHECKPOINTING FOR RENAME TABLE REBUILDING 有权
标题翻译：基于重构缓冲区的动态检测用于重命名表重建
公开(公告)号：US20140281414A1
公开(公告)日：2014-09-18
申请号：US13831488
申请日：2013-03-14
申请人： Ravi Iyengar , Prarthna Santhanakrishnan
发明人： Ravi Iyengar , Prarthna Santhanakrishnan
IPC分类号： G06F9/30
CPC分类号： G06F9/30098 , G06F9/384 , G06F9/3855 , G06F9/3863
摘要： Out-of-order CPUs, devices and methods diminish the time penalty from stalling the pipe to rebuild a rename table, such as due to a misprediction. A microprocessor can include a pipe that has a decoder, a dispatcher, and at least one execution unit. A rename table stores rename data, and a check-point table (“CPT”) stores rename data received from the dispatcher. A Re-Order Buffer (“ROB”) stores ROB data, and has a dynamic mapping relationship with the CPT. If the rename table is flushed, such as due to a misprediction, the rename table is rebuilt at least in part by concurrent copying of rename data stored in the CPT, in coordination with walking the ROB.
摘要翻译：无序的CPU，设备和方法减少了管道停止的时间，从而重建重命名表，例如由于错误预测。微处理器可以包括具有解码器，调度器和至少一个执行单元的管道。重命名表存储重命名数据，并且检查点表（“CPT”）存储从分派器接收的重命名数据。重新排序缓冲区（“ROB”）存储ROB数据，并且与CPT具有动态映射关系。如果重命名表被刷新，例如由于错误预测，则重命名表至少部分地通过并行复制存储在CPT中的重命名数据，与步行ROB协调来重建。

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