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1. 发明申请

US20130033593A1 Portable Retinal Camera and Image Acquisition Method 有权
标题翻译：便携式视网膜摄像机和图像采集方法
公开(公告)号：US20130033593A1
公开(公告)日：2013-02-07
申请号：US13645763
申请日：2012-10-05
申请人： Randal B. Chinnock , Fredrick G. Bargoot , George Grubner , Jason P. Julian , Sarah Latta , William Weber
发明人： Randal B. Chinnock , Fredrick G. Bargoot , George Grubner , Jason P. Julian , Sarah Latta , William Weber
IPC分类号： H04N7/18
CPC分类号： A61B3/14 , A61B3/0091
摘要： A camera for capturing an image of an object, for example an eye. The camera has at least two light sources and an image-sensing system having two image sensors. A multiple branch optical system transmits outgoing light from the light sources to the object, and transmits incoming light from the object to the image-sensing system. The multiple branch optical system includes an autofocusing element such as a variable power optical element that varies the focus of the incoming light. There is also an image display. There is a controller that controls the operation of the light sources, controls acquisition of images by the image-sensing system, and controls the display of images on the image display. The controller activates an autofocus light source and uses the resulting captured image to automatically adjust the image exposure parameters. The controller automatically adjusts the autofocusing element to improve the image focus, and then activates the second light source and acquires one or more images of the object while the second light source is activated.
摘要翻译：用于捕获物体（例如眼睛）的图像的照相机。相机具有至少两个光源和具有两个图像传感器的图像感测系统。多分支光学系统将来自光源的输出光发射到物体，并将来自物体的入射光发射到图像感测系统。多分支光学系统包括诸如可变功率光学元件的自动聚焦元件，其改变入射光的焦点。还有图像显示。控制器控制光源的操作，控制图像感测系统的图像采集，并控制图像显示上的图像显示。控制器激活自动对焦光源，并使用得到的拍摄图像自动调整图像曝光参数。控制器自动调整自动对焦元件以改善图像焦点，然后激活第二个光源并在第二个光源激活时获取对象的一个或多个图像。

3. 发明申请

US20110130632A1 Visualization Instrument 有权
公开(公告)号：US20110130632A1
公开(公告)日：2011-06-02
申请号：US12874035
申请日：2010-09-01
申请人： Thomas W. McGrail , Michael S. Pargett , David J. Miller , Yun Siung Tony Yeh , Randal B. Chinnock , George Grubner , Elizabeth Powell Goodrich , Richard L. Miller , Gary Vincent Palladino , Brian Hack
发明人： Thomas W. McGrail , Michael S. Pargett , David J. Miller , Yun Siung Tony Yeh , Randal B. Chinnock , George Grubner , Elizabeth Powell Goodrich , Richard L. Miller , Gary Vincent Palladino , Brian Hack
IPC分类号： A61B1/267
CPC分类号： A61B1/267 , A61B1/00016 , A61B1/00052 , A61B1/00103 , A61B1/00105 , A61B1/018 , A61B1/05 , G02B23/2423 , G02B23/2446
摘要： A visualization instrument comprising a display support component removably coupled to a component insertable into a target space. The insertable component includes a camera providing images of the target space. The images are presented in a display device supported by the display support component. The insertable component may be discarded after a permitted number of uses.

4. 发明授权

US09854962B2 Visualization instrument 有权
公开(公告)号：US09854962B2
公开(公告)日：2018-01-02
申请号：US12874058
申请日：2010-09-01
申请人： Thomas W. McGrail , Michael S. Pargett , David J. Miller , Yun Siung Tony Yeh , Randal B. Chinnock , George Grubner , Elizabeth Powell Goodrich , Paul Crosby Gregory , Gary Vincent Palladino , Brian Hack , Kristin Jugenheimer Size , Richard L. Miller
发明人： Thomas W. McGrail , Michael S. Pargett , David J. Miller , Yun Siung Tony Yeh , Randal B. Chinnock , George Grubner , Elizabeth Powell Goodrich , Paul Crosby Gregory , Gary Vincent Palladino , Brian Hack , Kristin Jugenheimer Size , Richard L. Miller
IPC分类号： A61B1/00 , A61B1/267 , A61B1/05 , G02B23/24 , A61B1/018
CPC分类号： A61B1/267 , A61B1/00016 , A61B1/00052 , A61B1/00103 , A61B1/00105 , A61B1/018 , A61B1/05 , G02B23/2423 , G02B23/2446
摘要： A visualization instrument comprising a display support component removably coupled to a component insertable into a target space. The insertable component includes a camera providing images of the target space. The images are presented in a display device supported by the display support component. The insertable component may be discarded after a permitted number of uses.

5. 发明授权

US09179831B2 Visualization instrument 有权
标题翻译：可视化仪器
公开(公告)号：US09179831B2
公开(公告)日：2015-11-10
申请号：US12874035
申请日：2010-09-01
申请人： Thomas W. McGrail , Michael S. Pargett , David J. Miller , Yun Siung Tony Yeh , Randal B. Chinnock , George Grubner , Elizabeth Powell Goodrich , Richard L. Miller , Gary Vincent Palladino , Brian Hack
发明人： Thomas W. McGrail , Michael S. Pargett , David J. Miller , Yun Siung Tony Yeh , Randal B. Chinnock , George Grubner , Elizabeth Powell Goodrich , Richard L. Miller , Gary Vincent Palladino , Brian Hack
IPC分类号： A61B1/267 , A61B1/00 , A61B1/05 , G02B23/24 , A61B1/018
CPC分类号： A61B1/267 , A61B1/00016 , A61B1/00052 , A61B1/00103 , A61B1/00105 , A61B1/018 , A61B1/05 , G02B23/2423 , G02B23/2446
摘要： A visualization instrument comprising a display support component removably coupled to a component insertable into a target space. The insertable component includes a camera providing images of the target space. The images are presented in a display device supported by the display support component. The insertable component may be discarded after a permitted number of uses.
摘要翻译：一种可视化仪器，包括可拆卸地联接到可插入到目标空间中的部件的显示器支撑部件。可插入部件包括提供目标空间的图像的相机。图像显示在由显示支持组件支持的显示设备中。可插入组件可以在允许的使用次数之后丢弃。

6. 发明申请

US20110130627A1 Visualization Instrument 有权
标题翻译：可视化仪器
公开(公告)号：US20110130627A1
公开(公告)日：2011-06-02
申请号：US12874058
申请日：2010-09-01
申请人： Thomas W. McGrail , Michael S. Pargett , David J. Miller , Yun Siung Tony Yeh , Randal B. Chinnock , George Grubner , Elizabeth Powell Goodrich , Paul Crosby Gregory , Gary Vincent Palladino , Brian Hack , Kristin Jugenheimer Size , Richard L. Miller
发明人： Thomas W. McGrail , Michael S. Pargett , David J. Miller , Yun Siung Tony Yeh , Randal B. Chinnock , George Grubner , Elizabeth Powell Goodrich , Paul Crosby Gregory , Gary Vincent Palladino , Brian Hack , Kristin Jugenheimer Size , Richard L. Miller
IPC分类号： A61B1/04
CPC分类号： A61B1/267 , A61B1/00016 , A61B1/00052 , A61B1/00103 , A61B1/00105 , A61B1/018 , A61B1/05 , G02B23/2423 , G02B23/2446
摘要： A visualization instrument comprising a display support component removably coupled to a component insertable into a target space. The insertable component includes a camera providing images of the target space. The images are presented in a display device supported by the display support component. The insertable component may be discarded after a permitted number of uses.
摘要翻译：一种可视化仪器，包括可拆卸地耦合到可插入到目标空间中的部件的显示器支撑部件。可插入部件包括提供目标空间的图像的相机。图像显示在由显示支持组件支持的显示设备中。可插入组件可以在允许的使用次数之后丢弃。

7. 发明授权

US08215774B2 Ocular surface interferometry (OSI) devices and systems for imaging and measuring ocular tear film layer thickness(es) 有权
标题翻译：用于成像和测量眼泪膜层厚度的眼表干涉测量（OSI）装置和系统
公开(公告)号：US08215774B2
公开(公告)日：2012-07-10
申请号：US12798324
申请日：2010-04-01
申请人： Donald R. Korb , William L. Weber , Randal B. Chinnock , Benjamin T. Gravely , Stephen M. Grenon , Michael Zelina
发明人： Donald R. Korb , William L. Weber , Randal B. Chinnock , Benjamin T. Gravely , Stephen M. Grenon , Michael Zelina
IPC分类号： A61B3/14 , A61B3/10
CPC分类号： A61B3/101 , A61B3/0025 , A61B3/0041 , A61B3/1005 , A61B3/14 , G06T7/0012 , G06T2207/30041
摘要： Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
摘要翻译：公开了用于测量眼泪膜的泪膜层厚度（TFLT），包括脂质层厚度（LLT）和/或水层厚度（ALT）的眼表干涉测量（OSI）装置，系统和方法。测量的TFLT可用于诊断干眼综合征（DES）。在某些公开的实施例中，可以控制多波长光源以照射眼泪膜。从多波长光源发射的光在泪膜中经历光波干涉相互作用。成像装置可以集中在泪膜的脂质层上，以捕获与第一图像中的背景信号结合的来自泪膜的镜面反射光的光波干涉相互作用。成像装置还可以聚焦在泪膜的脂质层上，以捕获包含存在于第一图像中的背景信号的第二图像。可以从第一图像中减去第二图像以减少和/或消除第一图像中的背景信号以产生所得图像。可以对所得图像进行处理和分析，以测量泪膜层厚度（TFLT），包括脂质层厚度（LLT）和/或水层厚度（ALT）。

8. 发明授权

US07883031B2 Ophthalmic drug delivery system 有权
标题翻译：眼科药物输送系统
公开(公告)号：US07883031B2
公开(公告)日：2011-02-08
申请号：US10851611
申请日：2004-05-20
申请人： James F. Collins, Jr. , Randal B. Chinnock , Jeffrey Melanson , Joseph Howard
发明人： James F. Collins, Jr. , Randal B. Chinnock , Jeffrey Melanson , Joseph Howard
IPC分类号： A61M11/06
CPC分类号： B05B17/0646 , A61F9/0008 , A61M11/005 , A61M11/041 , A61M11/042 , A61M11/065 , A61M2205/59 , A61M2210/0612 , B05B17/0623 , B05B17/0676
摘要： A fluid atomizer is disclosed. The fluid atomizer comprises a body having a proximal end and a distal end. A removable reservoir containing a fluid disposed therein is connected to the body. A discharge plate is disposed at the distal end, wherein the discharge plate includes a plurality of openings extending therethrough. An ultrasonic oscillator is disposed in the body for transmitting the fluid from the reservoir to the discharge plate and through the plurality of openings, wherein transmission of the fluid through the plurality of openings atomizes the fluid.
摘要翻译：公开了一种流体雾化器。流体雾化器包括具有近端和远端的主体。包含设置在其中的流体的可移除的储存器连接到主体。放电板设置在远端，其中放电板包括从其延伸穿过的多个开口。超声波振荡器设置在主体中，用于将流体从储存器传送到排放板并通过多个开口，其中通过多个开口的流体的传输使流体雾化。

9. 发明授权

US07187442B2 Polarized optical probes 有权
标题翻译：极化光学探针
公开(公告)号：US07187442B2
公开(公告)日：2007-03-06
申请号：US10835747
申请日：2004-04-30
申请人： Randal B. Chinnock , Jeffrey S. Melanson
发明人： Randal B. Chinnock , Jeffrey S. Melanson
IPC分类号： G01J4/00
CPC分类号： G01J4/04 , G01N21/21
摘要： A variably-polarizing optical probe assembly. The assembly includes an optical probe having one or more optical light delivery channels that emit incident light from the sample end of the probe toward a sample being investigated, and one or more optical light-receiving channels that receive incident light from the sample. A variably-polarizing substrate assembly is coupled to the sample end of the probe. The substrate assembly includes an optically transmitting substrate and one or more discrete polarizer areas on a face of the substrate, each such polarizer area defining a polarization orientation, with the polarizer areas together defining one or more different polarization orientations. The substrate assembly is arranged relative to the probe such that one polarizer area covers at least one light delivery channel and one polarizer area covers at least one light-receiving channel.
摘要翻译：可变偏振光学探针组件。组件包括具有一个或多个光学传输通道的光学探针，其将从探针的样品端朝向被研究的样品发射入射光，以及一个或多个接收来自样品的入射光的光接收通道。可变偏振衬底组件耦合到探针的样品端。衬底组件包括光学透射衬底和在衬底的表面上的一个或多个离散偏振器区域，每个这样的偏振器区域限定极化取向，偏振器区域一起限定一个或多个不同的偏振取向。衬底组件相对于探针布置，使得一个偏振器区域覆盖至少一个光输送通道，并且一个偏振器区域覆盖至少一个光接收通道。

10. 外观设计

USD453964S1 Sheath for cervical optical probe 失效
公开(公告)号：USD453964S1
公开(公告)日：2002-02-26
申请号：US29136964
申请日：2001-02-09
申请人： Richard M. Morrell , Stephen C. Parshley , Randal B. Chinnock
设计人： Richard M. Morrell , Stephen C. Parshley , Randal B. Chinnock

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