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1. 发明授权

US07870006B2 Methods and systems for managing clinical research information 有权
标题翻译：临床研究信息管理方法和系统
公开(公告)号：US07870006B2
公开(公告)日：2011-01-11
申请号：US10065159
申请日：2002-09-23
申请人： John Eric Tkaczyk , Maria Iatrou , Naresh Kesavan Rao
发明人： John Eric Tkaczyk , Maria Iatrou , Naresh Kesavan Rao
IPC分类号： G06Q50/00 , G06F19/00
CPC分类号： G06Q50/24 , G06F19/00 , G06F19/3418 , G06Q50/22 , G16H10/20 , G16H10/60
摘要： A method for managing clinical study (CS) information for a clinical research entity using a server system coupled to a centralized database and at least one client system is provided. The centralized database has a plurality of templates stored therein. The method includes receiving at the server system CS information relating to at least one patient involved in a clinical study wherein the CS information is entered through a user selected template displayed on the client system, storing CS information received at the server system in the centralized database, tracking CS information stored in the centralized database, updating the centralized database periodically with newly received CS information to maintain CS information, and providing CS information in response to an inquiry.
摘要翻译：提供了一种使用耦合到集中式数据库和至少一个客户端系统的服务器系统来管理临床研究实体的临床研究（CS）信息的方法。集中式数据库中存储有多个模板。该方法包括在服务器系统CS处接收与临床研究中涉及的至少一个患者有关的信息，其中通过在客户端系统上显示的用户选择的模板输入CS信息，将在服务器系统接收的CS信息存储在中央数据库中跟踪存储在集中式数据库中的CS信息，以新接收的CS信息周期性地更新集中式数据库，以维护CS信息，并响应于查询提供CS信息。

2. 发明授权

US08811707B2 System and method for distributed processing of tomographic images 有权
标题翻译：断层图像分布式处理的系统和方法
公开(公告)号：US08811707B2
公开(公告)日：2014-08-19
申请号：US13218236
申请日：2011-08-25
申请人： John Irvin Jackson , Darin Robert Okerlund , Bernhard Erich Hermann Claus , Maria Iatrou , Jed Douglas Pack
发明人： John Irvin Jackson , Darin Robert Okerlund , Bernhard Erich Hermann Claus , Maria Iatrou , Jed Douglas Pack
IPC分类号： G06K9/00 , G06T11/00
CPC分类号： G06K9/00 , G06T11/003 , G06T11/006 , G06T2211/412 , G06T2211/428
摘要： A system and method for distributed and coordinated image processing of tomographic images utilizing processors on a medical imaging device and a separate workstation is disclosed. The system includes an image acquisition device to acquire image data of a subject and an image processor to receive the image data therefrom. The image processor is programmed to reconstruct initial images of a region-of-interest (ROI) from the image data, identify initial images on which to perform image correction, and generate an image correction request for the images identified for image correction, with the image correction request specifying a processing operation to be performed on the respective images. The image processor is further programmed to transfer the reconstructed initial images to a separate workstation that automatically initiates the image correction upon verifying a presence of an image correction request on the initial images so as to generate corrected images.
摘要翻译：公开了一种使用医疗成像设备和单独工作站上的处理器进行分层和协调的图像处理的系统和方法。该系统包括用于获取被摄体的图像数据的图像获取装置和用于从其接收图像数据的图像处理器。图像处理器被编程为从图像数据重建感兴趣区域（ROI）的初始图像，识别在其上进行图像校正的初始图像，并且生成用于图像校正的图像的图像校正请求，其中图像校正请求指定要对各个图像执行的处理操作。图像处理器还被编程为将重构的初始图像传送到单独的工作站，其在验证在初始图像上存在图像校正请求时自动启动图像校正，以便产生校正图像。

3. 发明授权

US07627078B2 Methods and apparatus for detecting structural, perfusion, and functional abnormalities 有权
标题翻译：用于检测结构，灌注和功能异常的方法和装置
公开(公告)号：US07627078B2
公开(公告)日：2009-12-01
申请号：US10065689
申请日：2002-11-08
申请人： Jiang Hsieh , Ricardo Scott Avila , Maria Iatrou , Shankara B. Reddy , Peter Michael Edic
发明人： Jiang Hsieh , Ricardo Scott Avila , Maria Iatrou , Shankara B. Reddy , Peter Michael Edic
IPC分类号： G01N23/00
CPC分类号： A61B6/507 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/481 , A61B6/482 , G06F19/00 , Y10S378/901
摘要： A Multi-Energy Computed Tomography (MECT) System is provided. The system includes a radiation source rotatable about a patient, a radiation detector, and a computer coupled to the radiation source and the radiation detector wherein the computer is configured to receive data regarding a first energy spectrum of a scan of a head of the patient, receive data regarding a second energy spectrum of a scan of the head, and generate an image using the received data.
摘要翻译：提供多能计算层析成像（MECT）系统。该系统包括可围绕患者旋转的辐射源，辐射检测器和耦合到辐射源和辐射检测器的计算机，其中计算机被配置为接收关于患者头部的扫描的第一能量谱的数据，接收关于头部扫描的第二能量谱的数据，并使用接收的数据生成图像。

4. 发明授权

US07031426B2 Methods and system for detecting components of plaque 有权
标题翻译：检测斑块成分的方法和系统
公开(公告)号：US07031426B2
公开(公告)日：2006-04-18
申请号：US10625437
申请日：2003-07-23
申请人： Maria Iatrou , Ricardo Scott Avila , Peter Michael Edic , Jiang Hsieh , James Walter LeBlanc , Xiaoye Wu
发明人： Maria Iatrou , Ricardo Scott Avila , Peter Michael Edic , Jiang Hsieh , James Walter LeBlanc , Xiaoye Wu
IPC分类号： A61B6/03
CPC分类号： A61B5/02007 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/481 , A61B6/482 , A61B6/583 , A61B17/22 , A61B2090/374 , A61B2090/376
摘要： A method including detecting components of plaque using a multi-energy computed tomography (MECT) system is provided.
摘要翻译：提供了一种使用多能计算机断层摄影（MECT）系统检测斑块成分的方法。

5. 发明申请

US20130051643A1 SYSTEM AND METHOD FOR DISTRIBUTED PROCESSING OF TOMOGRAPHIC IMAGES 有权
标题翻译：用于分布式图像处理的系统和方法
公开(公告)号：US20130051643A1
公开(公告)日：2013-02-28
申请号：US13218236
申请日：2011-08-25
申请人： John Irvin Jackson , Darin Robert Okerlund , Bernhard Erich Hermann Claus , Maria Iatrou , Jed Douglas Pack
发明人： John Irvin Jackson , Darin Robert Okerlund , Bernhard Erich Hermann Claus , Maria Iatrou , Jed Douglas Pack
IPC分类号： G06K9/00
CPC分类号： G06K9/00 , G06T11/003 , G06T11/006 , G06T2211/412 , G06T2211/428
摘要： A system and method for distributed and coordinated image processing of tomographic images utilizing processors on a medical imaging device and a separate workstation is disclosed. The system includes an image acquisition device to acquire image data of a subject and an image processor to receive the image data therefrom. The image processor is programmed to reconstruct initial images of a region-of-interest (ROI) from the image data, identify initial images on which to perform image correction, and generate an image correction request for the images identified for image correction, with the image correction request specifying a processing operation to be performed on the respective images. The image processor is further programmed to transfer the reconstructed initial images to a separate workstation that automatically initiates the image correction upon verifying a presence of an image correction request on the initial images so as to generate corrected images.
摘要翻译：公开了一种使用医疗成像设备和单独工作站上的处理器进行分层和协调的图像处理的系统和方法。该系统包括用于获取被摄体的图像数据的图像获取装置和用于从其接收图像数据的图像处理器。图像处理器被编程为从图像数据重建感兴趣区域（ROI）的初始图像，识别在其上进行图像校正的初始图像，并且生成用于图像校正的图像的图像校正请求，其中图像校正请求指定要对各个图像执行的处理操作。图像处理器还被编程为将重构的初始图像传送到单独的工作站，其在验证在初始图像上存在图像校正请求时自动启动图像校正，以便产生校正图像。

6. 发明授权

US07382852B2 Method and apparatus for correcting motion in image reconstruction 有权
标题翻译：用于校正图像重建中运动的方法和装置
公开(公告)号：US07382852B2
公开(公告)日：2008-06-03
申请号：US11804861
申请日：2007-05-21
申请人： Peter Michael Edic , Maria Iatrou , Erdogan Cesmeli , Bruno De Man , Samit Basu
发明人： Peter Michael Edic , Maria Iatrou , Erdogan Cesmeli , Bruno De Man , Samit Basu
IPC分类号： G01N23/00
CPC分类号： A61B6/541 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/482 , A61B6/503 , A61B6/563 , G01N23/046 , G01N2223/419 , G01N2223/612 , G06T5/003 , G06T5/50 , G06T7/246 , G06T11/005 , G06T2207/10081 , G06T2207/30004 , G06T2211/408 , G06T2211/412 , Y10S378/901
摘要： One or more techniques are provided for adapting a reconstruction process to account for the motion of an imaged object or organ, such as the heart. In particular, projection data of the moving object or organ is acquired using a slowly rotating CT gantry. Motion data may be determined from the projection data or from images reconstructed from the projection data. The motion data may be used to reconstruct motion-corrected images from the projection data. The motion-corrected images may be associated to form motion-corrected volume renderings.
摘要翻译：提供一种或多种技术用于调整重建过程以解决成像对象或器官（例如心脏）的运动。特别地，使用缓慢旋转的CT台架来获取移动物体或器官的投影数据。可以从投影数据或从投影数据重建的图像确定运动数据。运动数据可用于从投影数据重建运动校正图像。可以将运动校正的图像相关联以形成运动校正的体积渲染。

7. 发明授权

US07885375B2 Method and system for X-ray imaging 失效
标题翻译： X射线成像方法与系统
公开(公告)号：US07885375B2
公开(公告)日：2011-02-08
申请号：US12254732
申请日：2008-10-20
申请人： Bruno Kristiaan Bernard De Man , Daniel David Harrison , Maria Iatrou , Brian Patrick Smyth , Zhye Yin , Samit Kumar Basu , Souma Sengupta , Peter Claudius Sanza
发明人： Bruno Kristiaan Bernard De Man , Daniel David Harrison , Maria Iatrou , Brian Patrick Smyth , Zhye Yin , Samit Kumar Basu , Souma Sengupta , Peter Claudius Sanza
IPC分类号： G01N23/00
CPC分类号： A61B6/032 , A61B6/027 , A61B6/4014 , A61B6/4028 , A61B6/4085 , A61B6/4266
摘要： A technique is provided for imaging a field of view using an X-ray source comprising two or more emission points. The two or more emission points may be independently operated. Independent operation of the two or more emission points in performed in accordance with a list of commands that specifies the operation of the emission points. The list of commands, in one embodiment, is stored in a sequence buffer. In other embodiments, the list of commands is generated for a given usage, without being stored in a sequence buffer.
摘要翻译：提供了一种使用包括两个或更多个发射点的X射线源对视场成像的技术。两个或更多个发射点可以独立地操作。根据指定发射点的操作的命令的列表来执行两个或更多个发射点的独立操作。在一个实施例中，命令列表存储在序列缓冲器中。在其他实施例中，为给定的使用生成命令列表，而不被存储在序列缓冲器中。

8. 发明申请

US20090161816A1 METHOD AND SYSTEM FOR X-RAY IMAGING 失效
标题翻译： X射线成像的方法和系统
公开(公告)号：US20090161816A1
公开(公告)日：2009-06-25
申请号：US12254732
申请日：2008-10-20
申请人： Bruno Kristiaan Bernard De Man , Daniel David Harrison , Maria Iatrou , Brian Patrick Smyth , Zhye Yin , Samit Kumar Basu , Souma Sengupta , Peter Claudius Sanza
发明人： Bruno Kristiaan Bernard De Man , Daniel David Harrison , Maria Iatrou , Brian Patrick Smyth , Zhye Yin , Samit Kumar Basu , Souma Sengupta , Peter Claudius Sanza
IPC分类号： A61B6/00 , H05G1/70
CPC分类号： A61B6/032 , A61B6/027 , A61B6/4014 , A61B6/4028 , A61B6/4085 , A61B6/4266
摘要： A technique is provided for imaging a field of view using an X-ray source comprising two or more emission points. The two or more emission points may be independently operated. Independent operation of the two or more emission points in performed in accordance with a list of commands that specifies the operation of the emission points. The list of commands, in one embodiment, is stored in a sequence buffer. In other embodiments, the list of commands is generated for a given usage, without being stored in a sequence buffer.
摘要翻译：提供了一种使用包括两个或更多个发射点的X射线源对视场成像的技术。两个或更多个发射点可以独立地操作。根据指定发射点的操作的命令的列表来执行两个或更多个发射点的独立操作。在一个实施例中，命令列表存储在序列缓冲器中。在其他实施例中，为给定的使用生成命令列表，而不被存储在序列缓冲器中。

9. 发明授权

US07428292B2 Method and system for CT imaging using multi-spot emission sources 有权
标题翻译：使用多点发射源进行CT成像的方法和系统
公开(公告)号：US07428292B2
公开(公告)日：2008-09-23
申请号：US11563061
申请日：2006-11-24
申请人： Bruno K. B. De Man , Colin R. Wilson , Bernhard Claus , Maria Iatrou , James W. LeBlanc , Dirk Bequé , Samit Kumar Basu , Mark Vermilyea , Zhye Yin
发明人： Bruno K. B. De Man , Colin R. Wilson , Bernhard Claus , Maria Iatrou , James W. LeBlanc , Dirk Bequé , Samit Kumar Basu , Mark Vermilyea , Zhye Yin
IPC分类号： G01N23/00
CPC分类号： G01N23/046 , A61B6/032 , A61B6/4028 , A61B6/4085 , G01N2223/419 , G01N2223/612
摘要： A CT imaging system includes a rotatable gantry having an opening to receive an object to be scanned. A plurality of x-ray emission sources are attached to the rotatable gantry, each x-ray emission source configured to emit x-rays in a conebeam toward the object. The CT imaging system also includes a plurality of x-ray detector arrays attached to the gantry and positioned to receive x-rays passing through the object. At least one x-ray detector array of the plurality of x-ray detector arrays is configured to receive x-rays from more than one x-ray emission source.
摘要翻译： CT成像系统包括具有用于接收待扫描物体的开口的可旋转机架。多个x射线发射源附着在可旋转机架上，每个X射线发射源被配置为朝向物体发射锥形束中的x射线。 CT成像系统还包括多个附接到台架的X射线检测器阵列，并被定位成接收通过物体的X射线。多个X射线检测器阵列中的至少一个X射线检测器阵列被配置为从多于一个x射线发射源接收x射线。

10. 发明授权

US06765983B2 Method and apparatus for imaging a region of dynamic tissue 失效
标题翻译：用于成像动态组织区域的方法和装置
公开(公告)号：US06765983B2
公开(公告)日：2004-07-20
申请号：US10318909
申请日：2002-12-13
申请人： Weizhong Yan , Peter Michael Edic , Maria Iatrou , Kai Frank Goebel , Erdogan Cesmeli
发明人： Weizhong Yan , Peter Michael Edic , Maria Iatrou , Kai Frank Goebel , Erdogan Cesmeli
IPC分类号： A61B603
CPC分类号： A61B6/469 , A61B6/032 , A61B6/5264 , A61B6/541 , A61B6/563 , Y10S378/901
摘要： A technique is provided for reducing motion-related artifacts present in CT images attributable to the dynamic nature of the imaged tissue or the time-varying concentration of a contrast agent. A region of interest that encompasses a structure of diagnostic significance is selected. For projections acquired by the various rows of detectors in a multi-slice CT imaging system, the portions of the projections attributable to the projection of the region of interest are averaged for each view angle. The projections containing these averaged values are then combined with the projections which do not encompass the region of interest. The combined projection set may be reconstructed to form a CT image of the dynamic tissue. In addition, a smoothing step may be performed to interpolate projection values around the region of interest to smooth the visual transition to the unaveraged portions of the image.
摘要翻译：提供了一种技术，用于减少归因于成像组织的动态特性或造影剂的时变浓度的CT图像中存在的运动相关假象。选择包含诊断意义的结构的感兴趣区域。对于由多层CT成像系统中的各行检测器获取的投影，可以对于每个视角对平均感兴趣区域的投影的投影的部分进行平均。然后将包含这些平均值的投影与不包含感兴趣区域的投影组合。可以重组组合投影集以形成动态组织的CT图像。此外，可以执行平滑步骤来内插围绕感兴趣区域的投影值，以平滑对图像的未平面部分的视觉转换。

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