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1. 发明授权

US5494592A Apheresis apparatus and method 失效
标题翻译：分离装置和方法
公开(公告)号：US5494592A
公开(公告)日：1996-02-27
申请号：US372890
申请日：1995-01-13
申请人： Allen Latham, Jr. , Glen E. Jorgensen , Theodoor H. S. Sibinga , Joseph R. Plante , Tracey E. Knapp
发明人： Allen Latham, Jr. , Glen E. Jorgensen , Theodoor H. S. Sibinga , Joseph R. Plante , Tracey E. Knapp
IPC分类号： A61M1/02 , A61M1/36 , A61M37/00 , B01D21/26
CPC分类号： A61M1/3693 , A61M1/3696 , A61M2205/331 , B04B2005/0464 , B04B2005/0471
摘要： An apheresis apparatus and method is disclosed for increasing the purity and yield of platelets separated from donated whole blood in a centrifuge. The whole blood in the centrifuge is diluted by recirculating fluid, such as plasma or saline, at a first flow rate, to mix with further withdrawn whole blood prior to entering the centrifuge. As plasma is collected, it is recirculated through the centrifuge at a second flow rate to further improve the separation between the intermediate density components, i.e., platelets and white blood cells in the "buffy coat." The plasma is then recirculated through the centrifuge at a third flow rate and platelets are displaced out of the centrifuge while the plasma is recirculating through the centrifuge at the third flow rate.
摘要翻译：公开了用于提高在离心机中从捐献的全血分离的血小板的纯度和产量的单采血液成像装置和方法。离心机中的全血通过再循环流体例如血浆或盐水以第一流速稀释，以便在进入离心机之前与进一步取出的全血混合。当血浆被收集时，其以第二流速再循环通过离心机，以进一步改善中间密度组分即“血沉棕黄层”中的血小板和白细胞之间的分离。然后等离子体以第三流速再循环通过离心机，血小板以第三流速再循环通过离心机，血小板从离心机中移出。

2. 发明授权

US5607579A Apheresis apparatus for separating an intermediate density component from whole blood 失效
标题翻译：用于从全血中分离中密度成分的单采血液分离装置
公开(公告)号：US5607579A
公开(公告)日：1997-03-04
申请号：US536499
申请日：1995-09-28
申请人： Allen Latham, Jr. , Glen E. Jorgensen , Theodoor H. S. Sibinga , Joseph R. Plante , Tracey E. Knapp
发明人： Allen Latham, Jr. , Glen E. Jorgensen , Theodoor H. S. Sibinga , Joseph R. Plante , Tracey E. Knapp
IPC分类号： A61M1/02 , A61M1/36 , B01D21/26 , A61M1/38 , B01D21/32 , B04B11/02
CPC分类号： A61M1/3693 , A61M1/3696 , A61M2205/331 , B04B2005/0464 , B04B2005/0471
摘要： An apheresis apparatus for increasing the purity and yield of platelets separated from donated whole blood by centrifugation incorporates a centrifuge for separating whole blood into lower, intermediate, and higher density components. The centrifuge has inlet and outlet ports in selective fluid communication with a container for receiving lower density blood component from the outlet port. A pump is coupled to the container and the inlet port for recirculating lower density blood component from the first container through the inlet port into the centrifuge at a first, substantially constant, rate so as to widen the region of the centrifuge occupied by the intermediate density component without causing the intermediate density component to exit the centrifuge, and subsequently at a second rate, so as to displace intermediate density component from the centrifuge.
摘要翻译：用于通过离心提高与所捐献的全血分离的血小板的纯度和产量的分离装置包括用于将全血分离成较低，中等和较高密度组分的离心机。离心机具有与容器选择性流体连通的入口和出口端口，用于从出口端口接收较低密度的血液成分。泵联接到容器和入口端口，用于将第一容器的较低密度的血液成分从第一容器通过入口端口以第一，基本上恒定的速率再循环到离心机中，以便扩大离心机的由中间密度占据的区域组分，而不会使中间密度组分离开离心机，然后以第二速率离心，以便从离心机中取代中间密度组分。

3. 外观设计

USD377685S Blood withdrawal and separation set 失效
公开(公告)号：USD377685S
公开(公告)日：1997-01-28
申请号：US44778
申请日：1995-09-26
申请人： Theodoor H. S. Sibinga , Joseph R. Plante , Andrew Lanciano , James R. Loible , Robert B. Carr, Jr. , David W. Newby , Tracey E. Knapp
设计人： Theodoor H. S. Sibinga , Joseph R. Plante , Andrew Lanciano , James R. Loible , Robert B. Carr, Jr. , David W. Newby , Tracey E. Knapp

4. 发明授权

US08480559B2 Urethral support system 有权
标题翻译：尿道支持系统
公开(公告)号：US08480559B2
公开(公告)日：2013-07-09
申请号：US12441123
申请日：2007-09-12
申请人： Tracey E. Knapp , Ken Butcher , Noah Meade , Stephen Laffoon , Charles Jacobs
发明人： Tracey E. Knapp , Ken Butcher , Noah Meade , Stephen Laffoon , Charles Jacobs
IPC分类号： A61F2/00 , A61F13/00 , A61F2/02
CPC分类号： A61B17/06109 , A61B50/30 , A61B50/33 , A61B2017/00429 , A61B2017/00464 , A61B2017/00805 , A61B2017/06009 , A61B2017/06042 , A61B2017/06076 , A61F2/0045 , A61F2/0095
摘要： A urethral support system is described, including an introducer device and tissue implant. The introducer device may include a needle with multiple curves, some of the curves having multiple radii. A sheath assembly may be utilized to assist the passing of the tissue implant through a patient's tissue. The sheath assembly may include connectors configured to connect the sheath assembly to an end of the needle and a tab configured to detachably couple sheath sides over the tissue implant.
摘要翻译：描述了一种尿道支撑系统，包括导引器装置和组织植入物。导引器装置可以包括具有多个曲线的针，一些曲线具有多个半径。可以使用护套组件来帮助组织植入物通过患者组织。护套组件可以包括被配置为将护套组件连接到针的端部的连接器以及被配置成将鞘侧可拆卸地连接在组织植入物上的突出部。

5. 发明授权

US08597261B2 Ureteral access sheath 有权
标题翻译：输尿管通路鞘
公开(公告)号：US08597261B2
公开(公告)日：2013-12-03
申请号：US10840882
申请日：2004-05-07
申请人： Tracey E. Knapp
发明人： Tracey E. Knapp
IPC分类号： A61M25/00
CPC分类号： A61B17/0218 , A61B1/307 , A61B1/32 , A61B2017/0225 , A61M25/0032 , A61M25/0097 , A61M25/01 , A61M25/0662 , A61M25/09 , A61M29/02 , A61M2025/0037 , A61M2025/0177
摘要： In one embodiment, an access sheath includes a sheath assembly including sheath tubing, the sheath tubing having a main lumen and a secondary lumen that extends along the length of the main lumen, the main lumen being large enough to receive an endoscope.
摘要翻译：在一个实施例中，入口护套包括鞘组件，其包括护套管，护套管具有主管腔和沿主管腔长度延伸的次管腔，主管腔足够大以接收内窥镜。

6. 发明授权

US07907991B2 System and method for marking body cavities 有权
标题翻译：用于标记体腔的系统和方法
公开(公告)号：US07907991B2
公开(公告)日：2011-03-15
申请号：US11070813
申请日：2005-03-02
申请人： Tracey E. Knapp
发明人： Tracey E. Knapp
IPC分类号： A61M25/00 , A61B6/00 , A61B5/05
CPC分类号： A61B90/39 , A61B2090/3937
摘要： Systems and methods for marking a body cavity. In one embodiment, a system includes means for inspecting a body cavity, and means for visibly marking the body cavity so as to convey visual information regarding the body cavity. In one embodiment, a method includes inspecting a body cavity and marking the body cavity with a marking material to provide a visual indication regarding the cavity. In one embodiment, a marking material for marking a body cavity includes a radiopaque contrast agent that is viewable through fluoroscopy and a colored dye that is viewable using an internal viewing device.
摘要翻译：用于标记体腔的系统和方法。在一个实施例中，系统包括用于检查体腔的装置，以及用于可视地标记体腔以便传达关于体腔的视觉信息的装置。在一个实施例中，一种方法包括检查体腔并用标记材料标记体腔以提供关于腔的视觉指示。在一个实施例中，用于标记体腔的标记材料包括通过荧光透视可观看的不透射线造影剂和可使用内部观察装置观察的有色染料。

7. 发明申请

US20100234681A1 URETHRAL SUPPORT SYSTEM 有权
标题翻译： URETHRAL支持系统
公开(公告)号：US20100234681A1
公开(公告)日：2010-09-16
申请号：US12441123
申请日：2007-09-12
申请人： Tracey E. Knapp , Ken Butcher , Noah Meade , Stephen Laffoon , Charles Jacobs
发明人： Tracey E. Knapp , Ken Butcher , Noah Meade , Stephen Laffoon , Charles Jacobs
IPC分类号： A61B17/00
CPC分类号： A61B17/06109 , A61B50/30 , A61B50/33 , A61B2017/00429 , A61B2017/00464 , A61B2017/00805 , A61B2017/06009 , A61B2017/06042 , A61B2017/06076 , A61F2/0045 , A61F2/0095
摘要： A urethral support system is described, including an introducer device and tissue implant. The introducer device may include a needle with multiple curves, some of the curves having multiple radii. A sheath assembly may be utilized to assist the passing of the tissue implant through a patient's tissue. The sheath assembly may include connectors configured to connect the sheath assembly to an end of the needle and a tab configured to detachably couple sheath sides over the tissue implant.
摘要翻译：描述了一种尿道支撑系统，包括导引器装置和组织植入物。导引器装置可以包括具有多个曲线的针，一些曲线具有多个半径。可以使用护套组件来帮助组织植入物通过患者组织。护套组件可以包括被配置为将护套组件连接到针的端部的连接器以及被配置成将鞘侧可拆卸地连接在组织植入物上的突出部。

8. 发明授权

US5387088A Peristaltic pump tube loading assembly 失效
标题翻译：蠕动泵管装载总成
公开(公告)号：US5387088A
公开(公告)日：1995-02-07
申请号：US183483
申请日：1994-01-18
申请人： Tracey E. Knapp , James R. Loible , Andrew P. Lanciano , Victor Sacco, Jr. , Nicholas D. Baruch
发明人： Tracey E. Knapp , James R. Loible , Andrew P. Lanciano , Victor Sacco, Jr. , Nicholas D. Baruch
IPC分类号： A61M1/10 , F04B43/12 , F04C5/00 , F04B43/08
CPC分类号： F04B43/1253
摘要： A peristaltic pump assembly for easy loading includes a pump housing having a curved surface. A stationary tubing manifold from which a loop of tubing extends is positioned in line with the curved surface. A pump rotor rotatable about an axis is positioned adjacent to the curved surface. The rotor has a groove located above the curved surface encircling the rotor for retaining and stretching the loop of tubing in loading position between the rotor and the manifold. During loading, a notch located on the rotor progressively captures and urges the tubing downward between the curved surface and the pump rotor when the rotor is rotated.
摘要翻译：用于容易加载的蠕动泵组件包括具有弯曲表面的泵壳体。一条固定的管道歧管，其中管道环延伸定位成与弯曲表面成一直线。可绕轴线旋转的泵转子邻近弯曲表面定位。转子具有位于围绕转子的弯曲表面上方的槽，用于在转子和歧管之间的装载位置保持和拉伸管道环。在加载期间，当转子旋转时，位于转子上的凹口逐渐捕获并推动弯管表面和泵转子之间的管路向下。

9. 发明申请

US20110144485A1 SYSTEM AND METHOD FOR MARKING BODY CAVITIES 审中-公开
标题翻译：用于标记身体的系统和方法
公开(公告)号：US20110144485A1
公开(公告)日：2011-06-16
申请号：US13030687
申请日：2011-02-18
申请人： Tracey E. Knapp
发明人： Tracey E. Knapp
IPC分类号： A61B1/018 , A61B1/307 , A61B6/00
CPC分类号： A61B90/39 , A61B2090/3937
摘要： A surgical method, including inserting an internal viewing device via a ureter into a first calyx of a kidney, inspecting the first calyx with the internal viewing device, and determining whether the first calyx contains one or more stones. If the first calyx does contain one or more stones, it is marked with a first marking material, but if the first calyx does not contain one or more stones, it is marked with a second marking material different from the first marking material.
摘要翻译：一种手术方法，包括通过输尿管将内部观察装置插入肾脏的第一萼片，用内部观察装置检查第一花萼，以及确定第一花萼是否包含一个或多个石头。如果第一个花萼含有一个或多个石头，则标有第一个标记材料，但如果第一个花萼不含有一个或多个石头，则标有不同于第一标记材料的第二标记材料。

10. 发明授权

US07654989B2 Ureteral access sheath 有权
标题翻译：输尿管通路鞘
公开(公告)号：US07654989B2
公开(公告)日：2010-02-02
申请号：US10409527
申请日：2003-04-08
申请人： Tracey E. Knapp
发明人： Tracey E. Knapp
IPC分类号： A61M25/00
CPC分类号： A61B17/0218 , A61B1/307 , A61B1/32 , A61B2017/0225 , A61M25/0032 , A61M25/0097 , A61M25/01 , A61M25/0662 , A61M25/09 , A61M29/02 , A61M2025/0037 , A61M2025/0177
摘要： A ureteral access sheath comprises a sheath assembly having a main lumen and one or more secondary lumens. The sheath assembly can be configured with medical devices in both lumens, for example, a ureteroscope in the main working channel, and a guidewire, stone basket, grasper, laser fiber, or other surgical instrument in the secondary working channel. Or the sheath assembly can be configured with a medical device in one channel and the other lumen coupled to an irrigation means, such that irrigation of the surgical field can be efficiently accomplished even though the main working channel is substantially completely occupied by, e.g., a ureteroscope. Or the sheath assembly can be configured for irrigation through one lumen and aspiration through the other lumen, thereby creating a turbulent flow which washes the surgical field to facilitate removal of particles and debris.
摘要翻译：输尿管进入鞘包括具有主腔和一个或多个次管腔的护套组件。护套组件可以配置有两个内腔中的医疗装置，例如主工作通道中的输尿管镜，以及辅助工作通道中的导丝，石筐，抓紧器，激光光纤或其他手术器械。或者护套组件可以被配置为具有一个通道中的医疗装置，而另一个管腔与冲洗装置联接，使得即使主工作通道基本上完全被例如一个输尿管镜或者鞘组件可被配置用于通过一个内腔进行灌洗并通过另一个腔进行抽吸，从而产生湍流，洗涤手术区域以便于去除颗粒和碎屑。

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