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1. 外观设计

USD561054S1 Prism of sensor chip for biochemical analysis 有权
公开(公告)号：USD561054S1
公开(公告)日：2008-02-05
申请号：US29266476
申请日：2006-09-22
申请人： Nobuhiko Ogura , Katsuaki Muraishi , Hitoshi Shimizu , Masashi Hakamata , Yasunobu Sakaguchi , Yoshiyuki Kunuki
设计人： Nobuhiko Ogura , Katsuaki Muraishi , Hitoshi Shimizu , Masashi Hakamata , Yasunobu Sakaguchi , Yoshiyuki Kunuki

2. 外观设计

USD530638S1 Sensor chip for biochemical analyzer 有权
公开(公告)号：USD530638S1
公开(公告)日：2006-10-24
申请号：US29237426
申请日：2005-09-01
申请人： Hitoshi Shimizu , Katsuaki Muraishi , Tatsuo Fujikura , Hirohiko Tsuzuki , Kouji Kuruma , Masayasu Konishi , Yoshiyuki Kunuki
设计人： Hitoshi Shimizu , Katsuaki Muraishi , Tatsuo Fujikura , Hirohiko Tsuzuki , Kouji Kuruma , Masayasu Konishi , Yoshiyuki Kunuki

3. 发明授权

US07064837B2 Measuring sensor utilizing attenuated total reflection and measuring chip assembly 失效
标题翻译：测量传感器利用衰减全反射和测量芯片组装
公开(公告)号：US07064837B2
公开(公告)日：2006-06-20
申请号：US10120518
申请日：2002-04-12
申请人： Nobufumi Mori , Katsumi Hayashi , Masayuki Naya , Nobuhiko Ogura , Yoshiyuki Kunuki
发明人： Nobufumi Mori , Katsumi Hayashi , Masayuki Naya , Nobuhiko Ogura , Yoshiyuki Kunuki
IPC分类号： G01N21/55 , G01N1/10
CPC分类号： G01N21/553
摘要： Disclosed herein is a sensor utilizing attenuated total reflection. The sensor is constructed of a measuring chip, an optical system, and a measuring section. The measuring chip is equipped with a dielectric block, a thin film layer formed on the dielectric block, and a liquid-sample holding portion for holding a liquid sample. The optical system is used to make a light beam enter the dielectric block at various angles of incidence so that a total internal reflection condition is satisfied at an interface between the dielectric block and the thin film layer. The measuring section measures the state of attenuated total reflection, based on the intensity of the light beam totally reflected at the interface. The liquid-sample holding portion has an opening at its top surface. The sensor further has a lid supply mechanism for placing a lid on the opening to prevent evaporation of the liquid sample.
摘要翻译：这里公开了一种利用衰减全反射的传感器。传感器由测量芯片，光学系统和测量部分构成。测量芯片配备有介质块，形成在介质块上的薄膜层和用于保持液体样品的液体样品保持部分。光学系统用于使光束以不同的入射角进入介质块，使得在介电块和薄膜层之间的界面处满足全内反射条件。测量部分根据在界面全反射的光束的强度来测量衰减全反射的状态。液体样品保持部分在其顶表面上具有开口。传感器还具有用于将盖放置在开口上以防止液体样品蒸发的盖供给机构。

4. 发明授权

US07939023B2 Assay apparatus and sensor holding method 有权
标题翻译：测定装置和传感器保持方法
公开(公告)号：US07939023B2
公开(公告)日：2011-05-10
申请号：US11729888
申请日：2007-03-30
申请人： Yoshiyuki Kunuki
发明人： Yoshiyuki Kunuki
IPC分类号： G01N21/64 , G01N27/16 , G01N21/00 , C12M1/34 , G01N35/00 , G01N1/10
CPC分类号： G01N21/553 , G01N21/05 , G01N2021/0346 , Y10T436/112499 , Y10T436/113332 , Y10T436/114165 , Y10T436/117497
摘要： A sensor unit is retained on an assay stage of a surface plasmon resonance (SPR) assay apparatus. The sensor unit includes a prism having a sensing surface, disposed on an upper surface thereof, for detecting reaction of a sample. A flow cell is secured to the upper surface, and has a flow channel for flow of sample fluid containing the sample to the sensing surface. The sensor unit is set removably on the assay apparatus for optically measuring reaction of the sample. In sensor holding, the sensor unit is set on a stage surface of the assay stage by directing down the prism. In a pushing step, a lower surface of the prism is pushed on the stage surface in a first direction upright relative to the stage surface. Two holders push an upper face of the first and second ridges of the prism in the first direction.
摘要翻译：传感器单元保留在表面等离子体共振（SPR）测定装置的测定阶段。传感器单元包括具有检测表面的棱镜，设置在其上表面上，用于检测样品的反应。流动池被固定到上表面，并且具有用于将包含样品的样品流体流动到感测表面的流动通道。传感器单元可拆卸地设置在用于光学测量样品的反应的测定装置上。在传感器保持中，传感器单元通过向下指向棱镜而置于测定阶段的台面上。在推压步骤中，棱镜的下表面相对于台表面沿着第一方向被推到台面上。两个保持器沿第一方向推动棱镜的第一和第二脊的上表面。

5. 发明申请

US20100049217A1 CLIP PACKAGE FOR CLIP APPLICATION APPARATUS 失效
标题翻译：夹子应用设备的夹子包装
公开(公告)号：US20100049217A1
公开(公告)日：2010-02-25
申请号：US12544622
申请日：2009-08-20
申请人： Yoshiaki MATSUOKA , Yoshiyuki KUNUKI
发明人： Yoshiaki MATSUOKA , Yoshiyuki KUNUKI
IPC分类号： A61B17/10
CPC分类号： A61B17/1285 , A61B17/1222 , A61B17/1227 , A61B2017/0053
摘要： A multiple hemostatic clip application apparatus operates for tissue clamping in combination with an endoscope. For use with the clip application apparatus, a clip package is provided, and has a multiple clip assembly, which includes a clip device, and a fastening mechanism, disposed at a proximal end of the clip device, for fastening to a shaft head of an operating wire inserted through a flexible sheath of the clip application apparatus. A coupling device includes a casing for containing the multiple clip assembly in a manner movable from the fastening mechanism toward the flexible sheath, and a guide slider for pressing the shaft head toward the fastening mechanism, for fastening together. The fastening mechanism emerges from the casing, the shaft head being overlapped on the fastening mechanism in an axial direction of the multiple clip assembly.
摘要翻译：多个止血夹施加装置与内窥镜结合操作用于组织夹紧。为了与夹子施加装置一起使用，提供夹子包装，并且具有多个夹子组件，其包括夹子装置和紧固机构，该紧固装置设置在夹子装置的近端处，用于紧固到一个操作线穿过夹子施加装置的柔性护套插入。联接装置包括用于以可从紧固机构朝向柔性护套移动的方式容纳多个夹子组件的壳体，以及用于将轴头朝向紧固机构按压以用于紧固在一起的引导滑块。紧固机构从壳体露出，轴头沿着多个夹子组件的轴向方向重叠在紧固机构上。

6. 发明授权

US07450236B2 Measuring apparatus and sensor unit for same 有权
标题翻译：测量仪器和传感器单元相同
公开(公告)号：US07450236B2
公开(公告)日：2008-11-11
申请号：US10932071
申请日：2004-09-02
申请人： Yoshiyuki Kunuki , Hitoshi Shimizu , Toshihito Kimura
发明人： Yoshiyuki Kunuki , Hitoshi Shimizu , Toshihito Kimura
IPC分类号： G01N21/55
CPC分类号： G01N21/553
摘要： A sensor unit includes a dielectric block, a thin film layer and a reference surface. The thin film layer is formed on the upper surface of the dielectric block and the reference surface is coplanar with the upper surface of the dielectric block. The sensor unit is held in a predetermined position. A light beam is caused to enter the dielectric block to impinge upon the interface between the upper surface of the dielectric block and the thin film layer so that total internal reflection conditions are satisfied at the interface. Information on an analyte on the thin film layer is obtained on the basis of the light beam reflected at the interface. Displacement of the interface is measured by measuring displacement of the reference surface and the position of the sensor unit is adjusted according to the displacement of the reference surface.
摘要翻译：传感器单元包括介质块，薄膜层和参考表面。在介质块的上表面上形成薄膜层，并且参考表面与介质块的上表面共面。传感器单元保持在预定位置。导致光束进入介电块以撞击在介质块的上表面和薄膜层之间的界面上，使得在界面处满足全内反射条件。基于在界面处反射的光束获得关于薄膜层上的分析物的信息。通过测量参考表面的位移来测量界面的位移，并且根据参考表面的位移调节传感器单元的位置。

7. 外观设计

USD561623S1 Sensor chip for biochemical analysis 有权
标题翻译：传感器芯片进行生化分析
公开(公告)号：USD561623S1
公开(公告)日：2008-02-12
申请号：US29266470
申请日：2006-09-22
申请人： Nobuhiko Ogura , Katsuaki Muraishi , Hitoshi Shimizu , Masashi Hakamata , Yasunobu Sakaguchi , Hideyuki Morimoto , Hiroyuki Ota , Masayasu Konishi , Yoshiyuki Kunuki
设计人： Nobuhiko Ogura , Katsuaki Muraishi , Hitoshi Shimizu , Masashi Hakamata , Yasunobu Sakaguchi , Hideyuki Morimoto , Hiroyuki Ota , Masayasu Konishi , Yoshiyuki Kunuki

8. 外观设计

USD561053S1 Prism of sensor chip for biochemical analysis 有权
标题翻译：传感器芯片棱镜用于生化分析
公开(公告)号：USD561053S1
公开(公告)日：2008-02-05
申请号：US29266439
申请日：2006-09-21
申请人： Nobuhiko Ogura , Katsuaki Muraishi , Hitoshi Shimizu , Masashi Hakamata , Yasunobu Sakaguchi , Yoshiyuki Kunuki
设计人： Nobuhiko Ogura , Katsuaki Muraishi , Hitoshi Shimizu , Masashi Hakamata , Yasunobu Sakaguchi , Yoshiyuki Kunuki

9. 发明申请

US20070231210A1 Assay apparatus and sensor holding method 有权
标题翻译：测定装置和传感器保持方法
公开(公告)号：US20070231210A1
公开(公告)日：2007-10-04
申请号：US11729888
申请日：2007-03-30
申请人： Yoshiyuki Kunuki
发明人： Yoshiyuki Kunuki
IPC分类号： G01N21/64
CPC分类号： G01N21/553 , G01N21/05 , G01N2021/0346 , Y10T436/112499 , Y10T436/113332 , Y10T436/114165 , Y10T436/117497
摘要： A sensor unit is retained on an assay stage of a surface plasmon resonance (SPR) assay apparatus. The sensor unit includes a prism having a sensing surface, disposed on an upper surface thereof, for detecting reaction of a sample. A flow cell is secured to the upper surface, and has a flow channel for flow of sample fluid containing the sample to the sensing surface. The sensor unit is set removably on the assay apparatus for optically measuring reaction of the sample. In sensor holding, the sensor unit is set on a stage surface of the assay stage by directing down the prism. In a pushing step, a lower surface of the prism is pushed on the stage surface in a first direction upright relative to the stage surface. Two holders push an upper face of the first and second ridges of the prism in the first direction.
摘要翻译：传感器单元保留在表面等离子体共振（SPR）测定装置的测定阶段。传感器单元包括具有检测表面的棱镜，设置在其上表面上，用于检测样品的反应。流动池被固定到上表面，并且具有用于将包含样品的样品流体流动到感测表面的流动通道。传感器单元可拆卸地设置在用于光学测量样品的反应的测定装置上。在传感器保持中，传感器单元通过向下指向棱镜而置于测定阶段的台面上。在推压步骤中，棱镜的下表面相对于台表面沿着第一方向被推到台面上。两个保持器沿第一方向推动棱镜的第一和第二脊的上表面。

10. 发明申请

US20090275959A1 MULTIPLE CLIP DEVICE AND MULTIPLE CLIP APPLICATION APPARATUS 审中-公开
标题翻译：多个夹子装置和多个夹子应用装置
公开(公告)号：US20090275959A1
公开(公告)日：2009-11-05
申请号：US12434196
申请日：2009-05-01
申请人： Shengfu CUI , Takayuki IIDA , Yoshiyuki KUNUKI
发明人： Shengfu CUI , Takayuki IIDA , Yoshiyuki KUNUKI
IPC分类号： A61B17/10
CPC分类号： A61B17/122 , A61B17/0643 , A61B17/128 , A61B17/1285 , A61B2017/0053
摘要： A multiple clip device for hemostatic clamping of a lesion of a patient's body includes plural clips fastened to one another in a train, having first and second clips, a proximal end portion of the first clip being engaged with two claws of a distal end portion of the second clip. A dummy clip has claws in a shape of the claws of the clips, and is engaged with a proximal end portion of a final clip among the clips by the claws thereof. An end connector is for retention of the dummy clip, and for fastening in a removable manner to a shaft head at an end of an operating wire inserted in a flexible sheath of a multiple clip application apparatus. Specifically, the multiple clip application apparatus is constituted by the operating wire and the multiple clip device fastened thereto.
摘要翻译：用于对患者身体的病变进行止血夹持的多夹具装置包括在火车上彼此固定的多个夹具，具有第一和第二夹子，第一夹子的近端部分与两个爪的远端部分第二个剪辑。虚拟夹具具有夹子的爪的形状的爪，并且通过其爪与夹子中的最终夹的近端部分接合。端部连接器用于保持虚拟夹子，并且用于将可拆卸的方式紧固到插入多夹子施加装置的柔性护套中的操作线的端部处的轴头。具体地，多夹子施加装置由操作线和固定在其上的多夹持装置构成。

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