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1. 发明申请

US20060078526A1 Thickenable compositions 审中-公开
标题翻译：可食用组合物
公开(公告)号：US20060078526A1
公开(公告)日：2006-04-13
申请号：US11254595
申请日：2005-10-20
申请人： Matthew Boyd , John Mitchell , Colin Melia , Ian Jolliffe , Peter Dettmar , Frank Hampson
发明人： Matthew Boyd , John Mitchell , Colin Melia , Ian Jolliffe , Peter Dettmar , Frank Hampson
IPC分类号： A61K8/73
CPC分类号： C08L5/00 , C08L5/04 , C08L2205/02 , C11D3/222 , C08L2666/26 , C08L33/00
摘要： A composition comprises water, a first anionic polymer and a second anionic polymer. The first anionic polymer may be xanthan. The second anionic polymer may be selected from an alginate, a carboxymethylcellulose, an acrylate polymer, a carrageenan and a pectin. The composition is such that diluting it with water increases its viscosity.
摘要翻译：组合物包含水，第一阴离子聚合物和第二阴离子聚合物。第一阴离子聚合物可以是黄原胶。第二阴离子聚合物可以选自藻酸盐，羧甲基纤维素，丙烯酸酯聚合物，角叉菜胶和果胶。组合物使得用水稀释它使其粘度增加。

2. 发明申请

US20060292184A1 Bioadhesive liquid composition which is substantially free of water 审中-公开
标题翻译：基本上不含水的生物粘合剂液体组合物
公开(公告)号：US20060292184A1
公开(公告)日：2006-12-28
申请号：US10545974
申请日：2004-02-13
申请人： Johnathan Richardson , Colin Melia , Peter Dettmar , Frank Hampson , Ian Jolliffe
发明人： Johnathan Richardson , Colin Melia , Peter Dettmar , Frank Hampson , Ian Jolliffe
IPC分类号： A61K9/00
CPC分类号： A61K9/0095 , A61K9/006 , A61K31/00 , A61K31/734 , A61K47/10 , A61K47/34
摘要： A liquid composition for adherence to a bodily surface, notably to a bodily surface, especially a mucosal surface, comprises water-swellable polymer particles suspended in a water-miscible liquid diluent, wherein the liquid diluent is substantially free of water or includes an amount of water insufficient to fully swell the polymer particles. On admixture with water the composition thickens and becomes more adherent to surfaces. Thus the composition may be easy to administer but may become thick and adherent at the treatment site.
摘要翻译：用于粘附到身体表面，特别是身体表面，特别是粘膜表面的液体组合物包括悬浮在与水混溶的液体稀释剂中的水溶胀性聚合物颗粒，其中液体稀释剂基本上不含水或包括一定量的水不足以使聚合物颗粒完全溶胀。在与水混合时，组合物变稠并变得更粘附于表面。因此，组合物可能易于施用，但可能在治疗部位变稠和粘附。

3. 发明授权

US6165503A High strength capsules, process of preparing and using the same 失效
标题翻译：高强度胶囊，制备和使用它的过程
公开(公告)号：US6165503A
公开(公告)日：2000-12-26
申请号：US108809
申请日：1998-07-01
申请人： Olav G.ang.ser.o slashed.d , .O slashed.ivind Skaugrud , Peter Dettmar , Gudmund Sj.ang.k-Braek , Ian Jolliffe
发明人： Olav G.ang.ser.o slashed.d , .O slashed.ivind Skaugrud , Peter Dettmar , Gudmund Sj.ang.k-Braek , Ian Jolliffe
IPC分类号： A61K9/50 , A01N25/28 , A61K45/00 , A61K47/36 , A61P1/04 , A61P23/02 , A61P31/04 , B01J13/02 , C08B37/04 , C08B37/06 , C08B37/08 , A61K9/48 , A61K9/52 , A61K9/66
CPC分类号： B01J13/02 , Y10S514/962 , Y10S514/964
摘要： In the formation of capsules having a polyanionic polysaccharide core and a polycationic polysaccharide membrane layer, improved binding of the polycationic polysaccharide is achieved by including polyvalent ions, especially calcium ions, at the membrane forming step.
摘要翻译：在形成具有聚阴离子多糖核心和聚阳离子多糖膜层的胶囊中，通过在膜形成步骤包括多价离子，特别是钙离子，可以改善聚阳离子多糖的结合。

4. 发明申请

US20050244519A1 Bulking agent compositions 审中-公开
标题翻译：填充剂组合物
公开(公告)号：US20050244519A1
公开(公告)日：2005-11-03
申请号：US10520672
申请日：2003-07-11
申请人： Peter Dettmar , Kevin McKie , Michael Havler
发明人： Peter Dettmar , Kevin McKie , Michael Havler
IPC分类号： A23L1/05 , A23L1/059 , A23L1/29 , A23L1/308 , A61K9/14 , A61K31/734 , A61K36/00 , A61K36/68 , A61K47/02 , A61K47/10 , A61K47/14 , A61P1/10 , A61K35/78
CPC分类号： A61K47/10 , A23L33/21 , A23L33/22 , A23L33/29 , A23L33/40 , A23V2002/00 , A61K9/143 , A61K9/145 , A61K31/734 , A61K36/68 , A61K47/02 , A61K2300/00 , A23V2250/1628 , A23V2250/5106 , A23V2250/5026
摘要： The present invention provides an ingestible composition comprising a fibre or sacharide bulking agent, an ingestible silica, and at ingestible surfactant. The provision of the silica and the surfactant provides a synergistic benefit in the dispersal of the bulking agent in water thus making if easier and/or quicker to obtain an imbibable liquid. The bulking agent may be ispaghula, a natural material of benefit in promoting good bowel function.
摘要翻译：本发明提供了一种可摄入组合物，其包含纤维或梭花果实填充剂，可摄取二氧化硅和可摄入表面活性剂。二氧化硅和表面活性剂的提供在填充剂在水中的分散中提供了协同的益处，因此如果更容易和/或更快地获得可吸收的液体。填充剂可以是ispaghula，一种有利于促进肠功能的天然材料。

5. 发明申请

US20050240084A1 System 审中-公开
标题翻译：系统
公开(公告)号：US20050240084A1
公开(公告)日：2005-10-27
申请号：US10943512
申请日：2004-09-17
申请人： Alyn Morice , Peter Dettmar
发明人： Alyn Morice , Peter Dettmar
IPC分类号： A61B5/00 , A61B10/00 , G06F17/00 , G06F19/00
CPC分类号： G16H10/20 , G16H10/60 , G16H50/20
摘要： Diagnosing a medical condition of a patient includes receiving a plurality of pieces of information on a patient medical condition, assigning weighting factors to the pieces of information, and responsive to the assigned weighting factors, determining the patient medical condition. A system for diagnosing a patient medical condition includes an interface for receiving pieces of information on a patient medical condition, means for assigning weighting factors to the pieces of information, and means for determining the medical condition of the patient responsive to assigned weighting factors. An apparatus includes a data store for storing information relating to possible conditions, a processor that receives pieces of information relating to answers to questions posed to patients, a weighting assignor that assigns weighting factors to pieces of information, and a condition determining means that determines a patient medical condition responsive to the assigned weighting factors.
摘要翻译：诊断患者的医疗状况包括：接收关于患者医疗状况的多条信息，为所述信息分配加权因子，并响应于所分配的加权因子，确定患者的医疗状况。用于诊断患者医疗状况的系统包括用于接收关于患者医疗状况的信息的接口，用于向多条信息分配加权因子的装置，以及响应于所分配的加权因子来确定患者的医疗状况的装置。一种装置包括用于存储与可能条件相关的信息的数据存储器，接收与对患者提出的问题的答案相关的信息的处理器，将加权因子分配给信息片段的加权分配器;以及条件确定装置，患者医疗状况响应于所分配的加权因子。

6. 发明申请

US20070087038A1 GELLING COMPOSITIONS AND METHODS 审中-公开
标题翻译：凝胶组合物和方法
公开(公告)号：US20070087038A1
公开(公告)日：2007-04-19
申请号：US11538678
申请日：2006-10-04
申请人： JOHNATHAN RICHARDSON , PETER DETTMAR , OLAV GASEROD , TROND HELGERUD
发明人： JOHNATHAN RICHARDSON , PETER DETTMAR , OLAV GASEROD , TROND HELGERUD
IPC分类号： A61K47/00
CPC分类号： A61K31/715 , A23L33/30 , A61K9/0065 , A61K9/0095 , A61K9/20 , A61K9/2009 , A61K9/2018 , A61K9/2027 , A61K9/205 , A61K47/02 , A61K47/36
摘要： A method for the administration of a composition that augments the acidity of gastric fluid such that intra-gastric gelation of the polysaccharide:acid soluble multivalent cation formulation is initiated independent of endogenous acid secretion. The composition includes:(a) at least one of a polysaccharide, modified polysaccharide, or polysaccharide salt, each capable of ionotropic gelation, (b) at least one source of multivalent cations capable of solubilization at an acidic pH, and (c) at least one acid component capable of providing a controlled release of protons sufficient to solubilize the multivalent cations. The composition is capable of hydrating in aqueous media and subsequently forming a gel in a stomach when ingested, which gel resists peristaltic forces and remains in the stomach for an extended time. Also disclosed are edible compositions including this composition, as well as methods of inducing a satiety effect and providing controlled release of various components employing the composition of the invention.
摘要翻译：用于施用增加胃液酸度的组合物的方法，使得多糖：酸溶性多价阳离子制剂的胃内凝胶化独立于内源性酸分泌而开始。组合物包括：（a）多糖，改性多糖或多糖盐中的至少一种，各自能够具有离子型凝胶化，（b）至少一种能够在酸性pH下溶解的多价阳离子源，和（c）能够提供足以溶解多价阳离子的质子的受控释放的至少一种酸组分。该组合物能够在水性介质中水合，随后在摄入时在胃中形成凝胶，该凝胶抵抗蠕动力并在胃中长时间保留。还公开了包括该组合物的可食用组合物，以及诱导饱腹效果并使用本发明组合物提供控制释放各种组分的方法。

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