专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20060275807A1 Novel steroid 5alpha-reductase 审中-公开
标题翻译：新型类固醇5α-还原酶
公开(公告)号：US20060275807A1
公开(公告)日：2006-12-07
申请号：US11432424
申请日：2006-05-10
申请人： James Mohler , Mark Titus , Olga Kozyreva , O. Ford , Elsbieta Kawinski , Yun Li
发明人： James Mohler , Mark Titus , Olga Kozyreva , O. Ford , Elsbieta Kawinski , Yun Li
IPC分类号： C12Q1/68 , G01N33/574 , C12N9/02 , C12N15/861
CPC分类号： C12Q1/26 , C07K2319/21 , C07K2319/40 , C12N9/001 , C12N2799/022 , G01N33/57434
摘要： The invention provides an isolated, novel steroid 5α-reductase enzyme termed SRD5AIII. The protein has an estimated molecular weight of 37 kDa and is capable of converting testosterone to dihydrotestosterone at a pH of about 7.0. Also provided is a method for identifying inhibitors of SRD5AIII by contacting SRD5AIII with a test compound and measuring the activity of the enzyme. A reduced activity relative to a control indicates that the test compound is an inhibitor of SRD5AIII. A method is also provided for detecting androgen stimulated prostate cancer or recurrent prostate cancer in an individual. The method comprises obtaining a prostate biopsy from an individual and determining the level of expression of SRD5AIII gene or protein relative to a normal control. An increased expression of SRD5AIII relative to the control is indicative of androgen stimulated prostate cancer or recurrent prostate cancer.
摘要翻译：本发明提供了一种分离的新型类固醇5α-还原酶，称为SRD5AIII。蛋白质具有37kDa的估计分子量，并且能够在约7.0的pH下将睾酮转化为二氢睾酮。还提供了通过使SRD5AIII与测试化合物接触并测量酶的活性来鉴定SRD5AIII的抑制剂的方法。相对于对照的降低的活性表明测试化合物是SRD5AIII的抑制剂。还提供了用于检测个体中激素刺激的前列腺癌或复发性前列腺癌的方法。该方法包括从个体获得前列腺活检，并确定相对于正常对照的SRD5AIII基因或蛋白质的表达水平。 SRD5AIII相对于对照的增加的表达指示雄激素刺激的前列腺癌或复发性前列腺癌。

2. 发明申请

US20050013565A1 Fiber optic cable having a strength member 有权
标题翻译：具有强度构件的光纤电缆
公开(公告)号：US20050013565A1
公开(公告)日：2005-01-20
申请号：US10623231
申请日：2003-07-18
申请人： James Mohler , Kenneth Dunn , David Seddon , William Jackman
发明人： James Mohler , Kenneth Dunn , David Seddon , William Jackman
IPC分类号： G02B6/44 , H04N5/91
CPC分类号： G02B6/4422 , G02B6/4429
摘要： A fiber optic cable includes at least one optical waveguide, at least one strength member, and a jacket. The at least one strength member is a material having an average residual angle in the range of about 30 degrees to about 65 degrees during a bending test using a mandrel having a wire ratio (D/d) of about 200, The strength member is suitable, if necessary, for self-attaching to studs, hooks, or the like by bending it therearound and is also suitable for hardware such as P-clamps or other grips. In other embodiments, strength member 14 is annealed to relieve work hardening. Preferred embodiments use a steel strength member with a carbon content between about 0.30 percent to about 0.75 percent. Additionally, a coating may be applied to the strength member for environmental/corrosion protection or conductivity.
摘要翻译：光纤电缆包括至少一个光波导，至少一个强度构件和护套。所述至少一个强度构件是在使用具有约200的导线比（D / d）的心轴的弯曲试验期间具有在约30度至约65度范围内的平均残余角度的材料。强度构件是合适的如果需要，通过在其周围弯曲来自动附接到螺栓，钩等，并且也适用于诸如P型夹具或其他夹具的硬件。在其他实施例中，加强件14被退火以减轻加工硬化。优选的实施方案使用碳含量在约0.30％至约0.75％之间的钢强度构件。此外，涂层可以施加到强度构件上用于环境/腐蚀保护或导电性。

3. 发明申请

US20090145853A1 SYSTEM AND METHOD FOR CLEANING FUEL STORAGE TANKS 有权
标题翻译：清洁燃油储存罐的系统和方法
公开(公告)号：US20090145853A1
公开(公告)日：2009-06-11
申请号：US12329187
申请日：2008-12-05
申请人： Russell H. Hilsman , Douglas James Mohler
发明人： Russell H. Hilsman , Douglas James Mohler
IPC分类号： B01D35/30
CPC分类号： B08B9/08 , B60P3/14
摘要： Systems and methods for cleaning a fuel storage tank are disclosed. One system includes a plurality of filter elements mounted within a portable housing, and a hose in fluidic connection to at least some of the filter elements, the hose extendable from the portable housing and into an interior of a fuel storage tank, the hose having a nozzle including an inlet. The system also includes a pump in fluidic connection with one or more of the filter elements and configured to draw contents of the fuel storage tank into the hose and forward the contents through the one or more filter elements. The system further includes a video camera configured to capture video images of the interior of the fuel tank in an area proximate to the nozzle of the hose during cleaning.
摘要翻译：公开了用于清洁燃料储罐的系统和方法。一个系统包括安装在便携式外壳内的多个过滤器元件，以及与至少一些过滤元件流体连接的软管，软管可从便携式外壳延伸并进入燃料储存箱的内部，软管具有喷嘴包括一个入口。该系统还包括与一个或多个过滤器元件流体连接的泵并且构造成将燃料储存箱的内容物吸入软管中并通过一个或多个过滤器元件转发内容物。该系统还包括摄像机，其被配置为在清洁期间在靠近软管喷嘴的区域中捕获燃料箱内部的视频图像。

4. 发明申请

US20050213899A1 Fiber optic drop cables suitable for outdoor fiber to the subscriber applications 有权
标题翻译：适用于户外光纤的光纤分支电缆，可供用户应用
公开(公告)号：US20050213899A1
公开(公告)日：2005-09-29
申请号：US11099705
申请日：2005-04-06
申请人： William Hurley , David Seddon , James Mohler
发明人： William Hurley , David Seddon , James Mohler
IPC分类号： G02B6/00 , G02B6/44
CPC分类号： G02B6/4433 , G02B6/3849 , G02B6/3867 , G02B6/3887 , G02B6/4494
摘要： A fiber optic drop cable including at least one optical waveguide, at least one roving, and a cable jacket. In one embodiment, the at least one roving includes a resin matrix having a water-based acrylic composition that includes an ethylene-acrylic acid and a water-swellable component. The resin matrix has a percent by weight of about 10 percent or less of the flexible roving so that the at least of one roving is at least partially bonded with the cable jacket, thereby inhibiting buckling of the cable jacket. In another embodiment, a plurality of rovings are arranged in clusters in the cable for influencing the bonding between the rovings and cable jacket. Also, disclosed is a protective casing for protecting and routing optical fibers along with preconnectorized cable assemblies.
摘要翻译：一种光纤分支电缆，包括至少一个光波导，至少一个粗纱和电缆护套。在一个实施方案中，所述至少一种粗纱包括具有包含乙烯 - 丙烯酸和水溶胀性组分的水基丙烯酸组合物的树脂基质。所述树脂基体具有约10％或更小的柔性粗纱的重量百分比，使得至少一条粗纱至少部分地与电缆护套接合，从而抑制电缆护套的弯曲。在另一个实施例中，多个粗纱在电缆中以簇形式布置，以影响粗纱和电缆护套之间的接合。此外，公开了一种用于保护和布置光纤以及预连接电缆组件的保护壳体。

5. 发明授权

US07913856B2 System and method for cleaning fuel storage tanks 有权
标题翻译：燃料储罐清理系统及方法
公开(公告)号：US07913856B2
公开(公告)日：2011-03-29
申请号：US12329187
申请日：2008-12-05
申请人： Russell H. Hilsman , Douglas James Mohler
发明人： Russell H. Hilsman , Douglas James Mohler
IPC分类号： B01D29/00
CPC分类号： B08B9/08 , B60P3/14
摘要： Systems and methods for cleaning a fuel storage tank are disclosed. One system includes a plurality of filter elements mounted within a portable housing, and a hose in fluidic connection to at least some of the filter elements, the hose extendable from the portable housing and into an interior of a fuel storage tank, the hose having a nozzle including an inlet. The system also includes a pump in fluidic connection with one or more of the filter elements and configured to draw contents of the fuel storage tank into the hose and forward the contents through the one or more filter elements. The system further includes a video camera configured to capture video images of the interior of the fuel tank in an area proximate to the nozzle of the hose during cleaning.
摘要翻译：公开了用于清洁燃料储罐的系统和方法。一个系统包括安装在便携式外壳内的多个过滤器元件，以及与至少一些过滤元件流体连接的软管，软管可从便携式外壳延伸到燃料储存箱的内部，软管具有喷嘴包括一个入口。该系统还包括与一个或多个过滤器元件流体连接的泵并且构造成将燃料储存箱的内容物吸入软管中并通过一个或多个过滤器元件转发内容物。该系统还包括摄像机，其被配置为在清洁期间在靠近软管喷嘴的区域中捕获燃料箱内部的视频图像。

6. 发明申请

US20050213903A1 Fiber optic drop cables suitable for outdoor fiber to the subscriber applications 有权
标题翻译：适用于户外光纤的光纤分支电缆，可供用户应用
公开(公告)号：US20050213903A1
公开(公告)日：2005-09-29
申请号：US10809619
申请日：2004-03-25
申请人： James Mohler , David Seddon
发明人： James Mohler , David Seddon
IPC分类号： G02B6/00 , G02B6/44
CPC分类号： G02B6/4433 , G02B6/4494
摘要： A figure-eight fiber optic drop cable includes a messenger section and a carrier section connected by a web. The carrier section has at least one optical waveguide and at least one roving. In one embodiment, the carrier section has an average shrinkage of about 0.5% or less when separated from the messenger section during an average shrinkage test. Also the carrier section of the figure-eight fiber optic drop cable can have an average coefficient of thermal expansion (CTE) section after being separated from the messenger section of about 5.0×10−3%/° C. or less for preserving optical performance. Furthermore, a maximum delta attenuation of the at least one optical waveguide during thermal cycling may be about 0.3 dB/20 meters or less at a reference wavelength of about 1550 nm at a temperature of about −40° C. Other cable configurations are also possible with the invention.
摘要翻译：八号光纤分路电缆包括信使部分和通过网络连接的载体部分。载体部分具有至少一个光波导和至少一个粗纱。在一个实施方案中，当在平均收缩试验中与载体部分分离时，载体部分的平均收缩率为约0.5％或更小。而且，图八的光纤分支电缆的载体部分也可以在与信使部分分离后的平均热膨胀系数（CTE）为约5.0×10 -3％/℃。以下，以保持光学性能。此外，在约-40℃的温度下，在约1550nm的参考波长下，在热循环期间，至少一个光波导的最大δ衰减可以在约0.3dB / 20米或更小。其他电缆配置也是可能的与本发明。

7. 发明申请

US20050213900A1 Protective casings for optical fibers 有权
标题翻译：光纤保护套管
公开(公告)号：US20050213900A1
公开(公告)日：2005-09-29
申请号：US11099864
申请日：2005-04-06
申请人： Todd Rhyne , David Seddon , James Mohler , Joseph Cody , William Hurley
发明人： Todd Rhyne , David Seddon , James Mohler , Joseph Cody , William Hurley
IPC分类号： G02B6/00 , G02B6/44
CPC分类号： G02B6/4494 , G02B6/4432 , G02B6/4433
摘要： Disclosed is a fiber optic drop cable including at least one optical waveguide, at least one roving, and a cable jacket. In one embodiment, the at least one roving includes a resin matrix having a water-based acrylic composition that includes an ethylene-acrylic acid and a water-swellable component. The resin matrix has a percent by weight of about 10 percent or less of the flexible roving so that the at least of one roving is at least partially bonded with the cable jacket, thereby inhibiting buckling of the cable jacket. In another embodiment, a plurality of rovings are arranged in clusters in the cable for influencing the bonding between the rovings and cable jacket. Also, disclosed is a protective casing for protecting and routing optical fibers along with preconnectorized cable assemblies.
摘要翻译：公开了包括至少一个光波导，至少一个粗纱和电缆护套的光纤分支电缆。在一个实施方案中，所述至少一种粗纱包括具有包含乙烯 - 丙烯酸和水溶胀性组分的水基丙烯酸组合物的树脂基质。所述树脂基体具有约10％或更小的柔性粗纱的重量百分比，使得至少一条粗纱至少部分地与电缆护套接合，从而抑制电缆护套的弯曲。在另一个实施例中，多个粗纱在电缆中以簇形式布置，以影响粗纱和电缆护套之间的接合。此外，公开了一种用于保护和布置光纤以及预连接电缆组件的保护壳体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式