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1. 发明申请

US20130113359A1 FIELD EMISSION DEVICES INCLUDING NANOTUBES OR OTHER NANOSCALE ARTICLES 失效
标题翻译：包括纳米级或其他纳米级物品的场发射装置
公开(公告)号：US20130113359A1
公开(公告)日：2013-05-09
申请号：US12474415
申请日：2009-05-29
申请人： Timothy M. Swager , Hongwei Gu
发明人： Timothy M. Swager , Hongwei Gu
IPC分类号： H01J1/304
CPC分类号： H01J1/3042 , B82Y10/00 , B82Y99/00 , H01J1/304 , H01J9/025 , H01J63/02 , H01J63/06 , H01J2201/30469 , H01J2329/0455
摘要： The present invention provides devices comprising an assembly of carbon nanotubes, and related methods. In some cases, the carbon nanotubes may have enhanced alignment. Devices of the invention may comprise features and/or components which may enhance the emission of electrons and may lower the operating voltage of the devices. Using methods described herein, carbon nanotube assemblies may be manufactured rapidly, at low cost, and over a large surface area. Such devices may be useful in display applications such as field emission devices, or other applications requiring high image quality, low power consumption, and stability over a wide to temperature range.
摘要翻译：本发明提供了包括碳纳米管组件的装置和相关方法。在一些情况下，碳纳米管可以具有增强的对准。本发明的装置可以包括可以增强电子发射的特征和/或部件，并且可以降低装置的工作电压。使用本文所述的方法，碳纳米管组件可以以低成本，并且在大的表面积上快速制造。这样的器件可用于诸如场发射器件的显示应用，或者在宽到温度范围内需要高图像质量，低功耗和稳定性的其它应用中。

2. 发明授权

US08456073B2 Field emission devices including nanotubes or other nanoscale articles 失效
标题翻译：场致发射器件包括纳米管或其他纳米级物品
公开(公告)号：US08456073B2
公开(公告)日：2013-06-04
申请号：US12474415
申请日：2009-05-29
申请人： Timothy M. Swager , Hongwei Gu
发明人： Timothy M. Swager , Hongwei Gu
IPC分类号： G01N31/00 , G01N21/64
CPC分类号： H01J1/3042 , B82Y10/00 , B82Y99/00 , H01J1/304 , H01J9/025 , H01J63/02 , H01J63/06 , H01J2201/30469 , H01J2329/0455
摘要： The present invention provides devices comprising an assembly of carbon nanotubes, and related methods. In some cases, the carbon nanotubes may have enhanced alignment. Devices of the invention may comprise features and/or components which may enhance the emission of electrons and may lower the operating voltage of the devices. Using methods described herein, carbon nanotube assemblies may be manufactured rapidly, at low cost, and over a large surface area. Such devices may be useful in display applications such as field emission devices, or other applications requiring high image quality, low power consumption, and stability over a wide temperature range.
摘要翻译：本发明提供了包括碳纳米管组件的装置和相关方法。在一些情况下，碳纳米管可以具有增强的对准。本发明的装置可以包括可以增强电子发射的特征和/或部件，并且可以降低装置的工作电压。使用本文所述的方法，碳纳米管组件可以以低成本，并且在大的表面积上快速制造。这样的器件可用于诸如场致发射器件的显示应用，或者在宽的温度范围内需要高图像质量，低功耗和稳定性的其它应用中。

3. 发明授权

US09421167B2 Preparation of microvesicle-siRNA complexes and use thereof in AIDS treatment 有权
标题翻译：微泡 - siRNA复合物的制备及其在艾滋病治疗中的应用
公开(公告)号：US09421167B2
公开(公告)日：2016-08-23
申请号：US13700062
申请日：2010-12-09
申请人： Chenyu Zhang , Ke Zeng , Hongwei Gu , Minghui Cao , Liming Li
发明人： Chenyu Zhang , Ke Zeng , Hongwei Gu , Minghui Cao , Liming Li
IPC分类号： C12N15/11 , A61K9/127 , C12N15/113 , A61K9/51
CPC分类号： A61K9/127 , A61K9/5068 , A61K9/5184 , A61K31/713 , A61K47/6901 , C12N15/111 , C12N15/1131 , C12N15/1132 , C12N15/88 , C12N2310/14 , C12N2320/32 , Y10T428/2982
摘要： The present invention provides drugs for treating AIDS, which comprises microvesicles carrying anti-HIV specific siRNA. The present invention also provides a preparation method of the drug.
摘要翻译：本发明提供用于治疗AIDS的药物，其包含携带抗HIV特异性siRNA的微泡。本发明还提供了该药物的制备方法。

4. 发明授权

US09376679B2 Microvesicles carrying small interfering RNAs, preparation methods and uses thereof 有权
标题翻译：携带小干扰RNA的微泡，其制备方法和用途
公开(公告)号：US09376679B2
公开(公告)日：2016-06-28
申请号：US13700067
申请日：2010-05-26
申请人： Chenyu Zhang , Ke Zeng , Danqing Liu , Yujing Zhang , Hongwei Gu
发明人： Chenyu Zhang , Ke Zeng , Danqing Liu , Yujing Zhang , Hongwei Gu
IPC分类号： C12N15/113 , C12N15/11 , A61K9/127 , C12Q1/68 , C12N15/88
CPC分类号： C12N15/113 , A61K9/127 , C12N15/111 , C12N15/88 , C12N2310/14 , C12N2320/32 , C12Q1/68
摘要： Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles containing interfering RNAs are also provided. Microvesicles containing interfering RNAs, pharmaceutical compositions and kits comprising such microvesicles can be used to study the effects of interfering RNAs on receptor cells. As microvesicles containing interfering RNAs can stably, high efficiently and specifically deliver interfering RNAs, microvesicles containing interfering RNAs can be used to treat related diseases.
摘要翻译：提供了含有干扰RNA的微泡，其制备方法和用途。还提供了包含含有干扰RNA的微泡的药物组合物和试剂盒。含有干扰RNA的微泡，包含这种微泡的药物组合物和试剂盒可用于研究干扰RNA对受体细胞的影响。由于含有干扰RNA的微泡可以稳定，高效且特异性地递送干扰RNA，所以含有干扰RNA的微泡可用于治疗相关疾病。

5. 发明申请

US20130209544A1 MICROVESICLES CARRYING SMALL INTERFERING RNAS, PREPARATION METHODS AND USES THEREOF 有权
标题翻译：携带小干扰RNAs的微胶囊，其制备方法及其用途
公开(公告)号：US20130209544A1
公开(公告)日：2013-08-15
申请号：US13700067
申请日：2010-05-26
申请人： Chenyu Zhang , Ke Zeng , Danqing Liu , Yujing Zhang , Hongwei Gu
发明人： Chenyu Zhang , Ke Zeng , Danqing Liu , Yujing Zhang , Hongwei Gu
IPC分类号： C12N15/113 , C12Q1/68 , A61K9/127
CPC分类号： C12N15/113 , A61K9/127 , C12N15/111 , C12N15/88 , C12N2310/14 , C12N2320/32 , C12Q1/68
摘要： Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles containing interfering RNAs are also provided. Microvesicles containing interfering RNAs, pharmaceutical compositions and kits comprising such microvesicles can be used to study the effects of interfering RNAs on receptor cells. As microvesicles containing interfering RNAs can stably, high efficiently and specifically deliver interfering RNAs, microvesicles containing interfering RNAs can be used to treat related diseases.
摘要翻译：提供含有干扰RNA的微泡，其制备方法和用途。还提供了包含含有干扰RNA的微泡的药物组合物和试剂盒。含有干扰RNA的微泡，包含这种微泡的药物组合物和试剂盒可用于研究干扰RNA对受体细胞的影响。由于含有干扰RNA的微泡可以稳定，高效且特异性地递送干扰RNA，所以含有干扰RNA的微泡可用于治疗相关疾病。

6. 发明申请

US20130203837A1 PREPARATION OF MICROVESICLE-siRNA COMPLEXES AND USE THEREOF IN AIDS TREATMENT 有权
标题翻译：微卫星siRNA复合物的制备及其在艾滋病治疗中的应用
公开(公告)号：US20130203837A1
公开(公告)日：2013-08-08
申请号：US13700062
申请日：2010-12-09
申请人： Chenyu Zhang , Ke Zeng , Hongwei Gu , Minghui Cao , Liming Li
发明人： Chenyu Zhang , Ke Zeng , Hongwei Gu , Minghui Cao , Liming Li
IPC分类号： A61K9/127
CPC分类号： A61K9/127 , A61K9/5068 , A61K9/5184 , A61K31/713 , A61K47/6901 , C12N15/111 , C12N15/1131 , C12N15/1132 , C12N15/88 , C12N2310/14 , C12N2320/32 , Y10T428/2982
摘要： The present invention provides drugs for treating AIDS, which comprises microvesicles carrying anti-HIV specific siRNA. The present invention also provides a preparation method of the drug.
摘要翻译：本发明提供用于治疗AIDS的药物，其包含携带抗HIV特异性siRNA的微泡。本发明还提供了该药物的制备方法。

7. 发明申请

US20110233427A1 MAGNETITE-SILVER HETERODIMER NANOPARTICLES AND THEIR PREPARATION AND USE FOR TWO-PHOTON FLUORESCENCE 审中-公开
标题翻译： MAGNETITE-SILVER HETERLDER NANOPARTICLES及其制备和使用双光子荧光
公开(公告)号：US20110233427A1
公开(公告)日：2011-09-29
申请号：US12809560
申请日：2008-12-18
申请人： Jackie Y. Ying , Jiang Jiang , Hongwei Gu , Huilin Shao
发明人： Jackie Y. Ying , Jiang Jiang , Hongwei Gu , Huilin Shao
IPC分类号： G01J1/58 , C07K5/08 , C09K11/06 , B32B5/16 , B82Y5/00
CPC分类号： G01N21/6428 , B82Y30/00 , C01G49/08 , C01P2002/72 , C01P2002/84 , C01P2004/04 , C01P2004/64 , C01P2006/42 , G01N21/6458 , G01N33/5005 , G01N33/587 , G01N2021/6415 , G01N2021/6419 , Y10T428/2982
摘要： A heterodimer particle is provided which comprises a first component particle comprising magnetite and a second component particle comprising silver. The second component particle may have a structure and a particle size selected to generate two-photon fluorescence emission. The heterodimer particle may be irradiated with light of a wavelength selected to induce two-photon fluorescence emission, which is then detected. Tetramethylammonium hydroxide may be bonded to the surface of the first component and glutathione may be bonded to the surface of the second component. The heterodimer particle may be formed by preparing a magnetite particle and growing a silver particle on the magnetite particle, in the presence of 1,2-dodecanediol as a reducing agent.
摘要翻译：提供了一种异二聚体颗粒，其包含包含磁铁矿的第一组分颗粒和包含银的第二组分颗粒。第二组分颗粒可以具有选择用于产生双光子荧光发射的结构和粒径。可以用选择的波长的光照射异二聚体颗粒以诱导双光子荧光发射，然后检测该二聚体颗粒。四甲基氢氧化铵可以结合到第一组分的表面，并且谷胱甘肽可以结合到第二组分的表面。异1,2-二聚体颗粒可以通过在1,2-十二烷二醇作为还原剂的存在下制备磁铁矿颗粒并在磁铁矿颗粒上生长银颗粒而形成。

8. 发明授权

US07754444B2 Biofunctional magnetic nanoparticles for pathogen detection 有权
标题翻译：用于病原体检测的生物功能磁性纳米颗粒
公开(公告)号：US07754444B2
公开(公告)日：2010-07-13
申请号：US11159882
申请日：2005-06-23
申请人： Bing Xu , Pak Leung Ho , Hongwei Gu
发明人： Bing Xu , Pak Leung Ho , Hongwei Gu
IPC分类号： C12Q1/70 , C12Q1/04
CPC分类号： G01N33/54326 , G01N33/56911 , G01N33/56983 , Y10S977/90
摘要： This invention provides a method of detecting pathogens comprising the steps of: (a) contacting a sufficient amount of biofunctional magnetic nanoparticles with an appropriate sample for an appropriate period of time to permit the formation of complexes between the pathogens in the sample and the nanoparticles; (b) using a magnetic field to aggregate said complexes; and (c) detecting said complexes. The method may further comprise the additional step of removing said complexes. The biofunctional magnetic nanoparticles are preferably a conjugate of vancomycin and FePt. The pathogens may be bacteria or viruses, and the sample may be a solid, liquid, or gas. Detection may involve conventional fluorescence assay, enzyme-linked immunosorbent assay (ELISA), optical microscope, electron microscope, or a combination thereof. The sensitivity of detection for the method is at least as low as 10 colony forming units (cfu) of the pathogens in one milliliter of solution within one hour.
摘要翻译：本发明提供了一种检测病原体的方法，包括以下步骤：（a）将足量的生物功能磁性纳米颗粒与合适的样品接触适当的时间段，以允许样品中的病原体与纳米颗粒之间形成复合物; （b）使用磁场来聚集所述络合物; 和（c）检测所述复合物。该方法还可以包括去除所述复合物的附加步骤。生物功能磁性纳米颗粒优选为万古霉素和FePt的缀合物。病原体可以是细菌或病毒，样品可以是固体，液体或气体。检测可以涉及常规荧光测定，酶联免疫吸附测定（ELISA），光学显微镜，电子显微镜或其组合。在1小时内，该方法的检测灵敏度至少低于一毫升溶液中病原体的10个菌落形成单位（cfu）。

9. 发明申请

US20140302119A2 MICROVESICLES CARRYING SMALL INTERFERING RNAS PREPARATION METHODS AND USES THEREOF 有权
标题翻译：携带小干扰RNAS的微胶囊制备方法及其用途
公开(公告)号：US20140302119A2
公开(公告)日：2014-10-09
申请号：US13700067
申请日：2010-05-26
申请人： Chenyu Zhang , Ke Zeng , Danqing Liu , Yujing Zhang , Hongwei Gu
发明人： Chenyu Zhang , Ke Zeng , Danqing Liu , Yujing Zhang , Hongwei Gu
IPC分类号： C12N15/113 , C12Q1/68 , A61K9/127
CPC分类号： C12N15/113 , A61K9/127 , C12N15/111 , C12N15/88 , C12N2310/14 , C12N2320/32 , C12Q1/68
摘要： Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles containing interfering RNAs are also provided. Microvesicles containing interfering RNAs, pharmaceutical compositions and kits comprising such microvesicles can be used to study the effects of interfering RNAs on receptor cells. As microvesicles containing interfering RNAs can stably, high efficiently and specifically deliver interfering RNAs, microvesicles containing interfering RNAs can be used to treat related diseases.
摘要翻译：提供含有干扰RNA的微泡，其制备方法和用途。还提供了包含含有干扰RNA的微泡的药物组合物和试剂盒。含有干扰RNA的微泡，包含这种微泡的药物组合物和试剂盒可用于研究干扰RNA对受体细胞的影响。由于含有干扰RNA的微泡可以稳定，高效且特异性地递送干扰RNA，所以含有干扰RNA的微泡可用于治疗相关疾病。

10. 发明申请

US20120136164A1 NANOSTRUCTURED METALS 审中-公开
标题翻译：纳米结构金属
公开(公告)号：US20120136164A1
公开(公告)日：2012-05-31
申请号：US13260968
申请日：2010-03-30
申请人： Jackie Y. Ying , Nandanan Erathodiyil , Hongwei Gu , Huilin Shao , Jiang Jiang
发明人： Jackie Y. Ying , Nandanan Erathodiyil , Hongwei Gu , Huilin Shao , Jiang Jiang
IPC分类号： C07D307/33 , C07C303/36 , C07C29/145 , B01J35/02 , B01J23/89 , B01J37/04 , C30B7/14 , C07C67/30 , B01J23/42 , B82Y30/00 , B82B1/00 , B82B3/00 , B82Y99/00 , B82Y40/00
CPC分类号： C01G49/00 , B01J23/42 , B01J23/44 , B01J23/462 , B01J23/464 , B01J23/52 , B01J23/8906 , B01J35/002 , B01J35/023 , B01J35/06 , B01J37/086 , B22F1/0025 , B22F9/24 , B82Y30/00 , C01G7/00 , C01G55/00 , C01P2002/85 , C01P2004/04 , C01P2004/16 , C07B31/00 , C07B53/00 , C07B2200/07 , C07C29/143 , C07C67/31 , C07C231/18 , C07C303/40 , C30B7/14 , C30B11/12 , C30B29/02 , C30B29/60 , C07C33/30 , C07C33/20 , C07C33/24 , C07C69/68 , C07C311/19 , C07C235/12
摘要： The invention relates to a nanoparticulate material comprising long ultrathin metal nanowires, and to processes for making it. The nanoparticulate material may be used as a catalyst and, in the presence of a chiral modifier, can catalyse enantioselective reactions.
摘要翻译：本发明涉及包含长超薄金属纳米线的纳米颗粒材料及其制备方法。纳米颗粒材料可以用作催化剂，并且在手性改性剂的存在下可以催化对映选择性反应。

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