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2. 发明申请

US20090048576A1 Managing Cross-contamination in Blood Samples Withdrawn from a Multilumen Catheter 审中-公开
标题翻译：管理从多次导管撤回的血液样本中的交叉污染
公开(公告)号：US20090048576A1
公开(公告)日：2009-02-19
申请号：US11860544
申请日：2007-09-25
申请人： Mark Ries Robinson , Mike Borrello , John O'Mahony , Richard Thompson , Dave Tobler , V. Gerald Grafe
发明人： Mark Ries Robinson , Mike Borrello , John O'Mahony , Richard Thompson , Dave Tobler , V. Gerald Grafe
IPC分类号： A61M25/01
CPC分类号： A61B5/150961 , A61B5/14532 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/155 , A61B5/157
摘要： The present invention comprises methods and apparatuses that can provide accurate measurement of glucose or other analytes from a multilumen catheter in the presence of infusion of substances, including glucose. Examples of “multilumen catheters” include central venous catheters having multiple lumens, midline catheters having multiple lumens, multiple catheters configured or emplaced such that their lumens are in proximity to each other, and, in the case of indwelling analyte sensors, a catheter with a lumen for infusion and an indwelling sensor spaced apart from the infusion lumen. For blood withdrawal, anti-cross contamination controls can prevent the entrainment of blood which might be contaminated with feeding fluids or medications that are administered through other lumens within the catheter and in proximity of the blood sampling port. Cross contamination can occur under various situations, and is known to occur when the patient is connected to a ventilator. The ventilator cyclically raises the intra-thoracic pressure and diminishes blood flow rate in the central veins returning to the heart. The diminished flow can increase the chances for cross-contamination when additional lumens are introducing fluids during a draw sample.
摘要翻译：本发明包括在存在输入物质（包括葡萄糖）的情况下可以提供来自多腔导管的葡萄糖或其它分析物的精确测量的方法和装置。 “多腔导管”的实例包括具有多个腔的中心静脉导管，具有多个腔的中线导管，配置或放置多个导管，使得它们的内腔彼此靠近，并且在留置分析物传感器的情况下，用于输注的内腔和与输液腔间隔开的留置传感器。为了取血，反交叉污染控制可以防止可能被导管内和在血液采样端口附近通过其他管腔给药液体或药物而被污染的血液夹带。交叉污染可以在各种情况下发生，并且已知当患者连接到通气机时发生交叉污染。呼吸机周期性地升高胸腔内压，并减少返回心脏的中央静脉血流量。减少的流量可以增加在抽取样品期间附加管腔引入流体时交叉污染的机会。

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