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    • 7. 发明授权
    • 생분자 고정화 링커
    • 生物分子的稳定链接
    • KR100819064B1
    • 2008-04-04
    • KR1020060129906
    • 2006-12-19
    • 재단법인대구경북과학기술원
    • 김현철이수근정상원
    • C07C323/51C07C323/50C07C323/24
    • C07C323/12C07D207/408C07D303/16G01N33/54353
    • A thiol derivative is provided to obtain an immobilization linker capable of controlling the surface characteristics of a solid substrate and immobilizing biomolecules such as protein and nucleic acid molecules stably to the surface of a substrate. A thiol derivative is represented by the formula of R-(CH2)m-(OCH2CH2)m-OCO-Z-Q. In the formula, R is a thiol group; Z is a C1-C12 alkylene, C1-C6 alkoxy or phenyl group; Q is a carboxyl, nitro, imide, epoxy, aldehyde, hydroxyl, amino or isocyanate group, and when Q is imide or epoxy group, the imide or epoxy group is directly bound to Z or indirectly bound to Z via -OCO- or -OCO-(CH2)n; n is an integer of 10-15; and m is an integer of 0-10.
    • 提供硫醇衍生物以获得能够控制固体底物的表面特性并将生物分子如蛋白质和核酸分子稳定地固定在基材表面的固定接头。 硫醇衍生物由式(R-(CH 2)m - (OCH 2 CH 2)m -OCO-Z-Q表示)。 在该式中,R为硫醇基; Z是C1-C12亚烷基,C1-C6烷氧基或苯基; Q是羧基,硝基,酰亚胺,环氧基,醛,羟基,氨基或异氰酸酯基,当Q是酰亚胺或环氧基时,酰亚胺或环氧基与Z直接结合或间接通过-OCO-或 - OCO-(CH 2)N; n为10-15的整数; m为0〜10的整数。
    • 8. 发明公开
    • 최소한 하나의 디카르복시디티올을 포함하는 퍼머형 모발의재형상용 조성물
    • 组合物可永久改性含有至少一种二硫代双酚的头发
    • KR1020080023330A
    • 2008-03-13
    • KR1020080019223
    • 2008-02-29
    • 로레알
    • 말레,제라드블라이세,크리스티앙
    • C07C323/50C07C323/51
    • A61K8/447A61K8/46A61Q5/04C07C323/52C07C323/58C07C323/60
    • A dicarboxydithiol, and a water-soluble reducing composition containing the dicarboxydithiol for reshaping the permanently waved hair are provided to reduce the damage to hair and to improve the curling maintenance. A dicarboxydithiol is a compound represented by the formula I or II, or the mineral or organic salt of the compound, wherein A is (CH2)n or (CH2)m-X-(CH2)p; R1 and R2 are independently OR3 or NR4R5; R3 is H, or a linear or branched C1-C5 alkyl group substituted or unsubstituted with at least one OR7; R7 is H or a C1-C3 alkoxy group; R4 and R5 are independently H, or a linear or branched C1-C5 alkyl group substituted or unsubstituted with one or two group selected from a hydroxyl group, a methoxy group, an ethoxy group, a methylamino group, an ethylamino group and a dimethylamino group.
    • 提供二羧基二硫醇和含有二羧基二硫醇以重塑永久挥发的头发的水溶性还原性组合物以减少对头发的损害并改善卷曲维持性。 二羧基二硫醇是由式I或II表示的化合物或化合物的矿物或有机盐,其中A是(CH 2)n或(CH 2)m -X-(CH 2)p; R1和R2独立地是OR3或NR4R5; R 3为H,或至少一个OR 7取代或未取代的直链或支链C 1 -C 5烷基; R7是H或C1-C3烷氧基; R 4和R 5独立地为H,或被选自羟基,甲氧基,乙氧基,甲基氨基,乙基氨基和二甲基氨基中的一个或两个基团取代或未取代的直链或支链C 1 -C 5烷基 。