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1. 发明公开

KR1020110128754A 극미량 시료 검출용 전기 바이오센서 无效
标题翻译：用于检测无限制样品的电生物传感器
公开(公告)号：KR1020110128754A
公开(公告)日：2011-11-30
申请号：KR1020110049181
申请日：2011-05-24
申请人： 한국생명공학연구원
发明人： 김민곤 , 신용범 , 안준형 , 이태한
IPC分类号： G01N27/327 , G01N27/406 , G01N33/48 , C12Q1/68
CPC分类号： G01N27/127 , G01N33/54306 , G01N33/5438 , C12Q1/6825 , C12Q2563/116 , G01N27/406 , G01N33/48
摘要： PURPOSE: An electric biosensor for detecting a micro sample is provided to improve the measuring sensitivity and quantitively analyze a micro sample by increasing the conductivity through the electric connection of nano-electrodes. CONSTITUTION: An electric detecting method of a micro sample using a biosensor comprises the following steps. In an electrically insulated nano-electrode(11) chip, a receptor molecule selectively coupled with a target object material is fixed and a biosensor is manufactured. A sample containing a target material coupled with the receptor molecule is added and reacted in the biosensor. The gold nanoparticle is processed and reacted in the nano-electrode chip reacted with the sample containing the target material. The gold ion is processed in the reacted gold nanoparticle. The electric conduction or impedance of the nano-electrode chip in which the gold ion is restored is measured. The target material which specially coupling the receptor molecule are detected.
摘要翻译：目的：提供一种用于检测微量样品的电生物传感器，以提高测量灵敏度，并通过纳米电极的电连接增加导电率来定量分析微样品。构成：使用生物传感器的微量样品的电检测方法包括以下步骤。在电绝缘的纳米电极（11）芯片中，选择性地与目标物质耦合的受体分子是固定的，并且制造生物传感器。加入含有与受体分子偶联的靶物质的样品，并在生物传感器中反应。金纳米颗粒在与含有靶材料的样品反应的纳米电极芯片中进行处理和反应。在反应的金纳米颗粒中处理金离子。测量其中恢复金离子的纳米电极芯片的导电或阻抗。检测到特异性偶联受体分子的靶物质。

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