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1. 发明授权

KR100447608B1 작약씨로부터 항암 및 항돌연변이성 트란스-레즈베라트롤및 그 유도체의 추출방법 失效
标题翻译： 작약씨从항암및항돌연변이성트란스 - 레즈베라트롤및그유도체의추출방작
公开(公告)号：KR100447608B1
公开(公告)日：2004-09-07
申请号：KR1020010033032
申请日：2001-06-12
申请人： 최상원 , 김종성
发明人： 최상원 , 김종성 , 배송자 , 김효진
IPC分类号： A61K36/65 , A61P35/00
摘要： PURPOSE: A method for extracting resvedratrol and derivatives thereof having high anticancer and antimutagenic effect from a Paeoniae radix seed is provided. Whereby, the compound can be used for a medicine for prevention and treatment of cancer and functional food material. CONSTITUTION: This resvedratrol and derivatives thereof are extracted by the process consisting of: removing grease from dried Paeoniae radix seed powder by adding n-hexane; concentrating under reduced pressure at room temperature after adding methanol to the defatted Paeoniae radix seed; obtaining an extract by column chromatography; and recrystallizing after separating using a sepadex LH-20 and fraction-high speed liquid chromatography.
摘要翻译：目的：提供一种从赤芍种子中提取具有高抗癌和抗突变作用的去氧维他命及其衍生物的方法。因此，该化合物可用于预防和治疗癌症和功能性食品材料的药物。组成：这种去氧维生素及其衍生物是通过以下方法提取的：通过加入正己烷从干燥的赤芍种子粉末中去除油脂; 将甲醇加入脱脂赤芍种子后，在室温下减压浓缩; 通过柱色谱法获得提取物; 并在分离后使用分离色谱LH-20和级分 - 高速液相色谱进行重结晶。

2. 发明公开

KR1020010070841A 작약씨로부터 항암 및 항돌연변이성 트란스-레즈베라트롤및 그 유도체의 추출방법 失效
标题翻译：方法或提取来自PAEONIAE RADIX SEED的抗生素和抗真菌TTRANS-RESVERATROL及其衍生物
公开(公告)号：KR1020010070841A
公开(公告)日：2001-07-27
申请号：KR1020010033032
申请日：2001-06-12
申请人： 최상원 , 김종성
发明人： 최상원 , 김종성 , 배송자 , 김효진
IPC分类号： A61K36/65 , A61P35/00
摘要： PURPOSE: A method for extracting resvedratrol and derivatives thereof having high anticancer and antimutagenic effect from a Paeoniae radix seed is provided. Whereby, the compound can be used for a medicine for prevention and treatment of cancer and functional food material. CONSTITUTION: This resvedratrol and derivatives thereof are extracted by the process consisting of: removing grease from dried Paeoniae radix seed powder by adding n-hexane; concentrating under reduced pressure at room temperature after adding methanol to the defatted Paeoniae radix seed; obtaining an extract by column chromatography; and recrystallizing after separating using a sepadex LH-20 and fraction-high speed liquid chromatography.
摘要翻译：目的：提供一种从芍药种子提取具有高抗癌和抗诱变作用的被研究者及其衍生物的方法。因此，该化合物可用于预防和治疗癌症和功能性食物材料的药物。构成：通过以下方法提取这种resvedratrol及其衍生物：通过加入正己烷从干燥的芍药粉中除去油脂; 在脱脂芍药种子加甲醇后，在室温下减压浓缩; 通过柱色谱法获得提取物; 并使用sepadex LH-20和分馏 - 高速液相色谱法分离后重结晶。

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