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1. 发明公开

KR1020050003815A 탄저균 치사독소에 의한 대식세포 반응 유전자 분석방법 失效
标题翻译：通过BACILLUS ANTHRACIS LETHAL TOXIN检测BACILLUS ANTHRACIS感染的MACROPHAGE反应基因的分析方法
公开(公告)号：KR1020050003815A
公开(公告)日：2005-01-12
申请号：KR1020030045320
申请日：2003-07-04
申请人： 주식회사 쎌앤젠 , 채영규
发明人： 채영규 , 서귀문 , 남정아 , 오광근
IPC分类号： C12Q1/68
摘要： PURPOSE: An analysis method of macrophage reaction gene by Bacillus anthracis lethal toxin is provided, which macrophage reaction gene is useful as a biomarker, so that the presence of Bacillus anthracis lethal toxin can be easily detected by using the biomarker. CONSTITUTION: The analysis method of macrophage reaction gene by Bacillus anthracis lethal toxin comprises the steps of: treating genes with Bacillus anthracis lethal toxin; measuring and comparing the expressions of the genes treated with and without the Bacillus anthracis lethal toxin in macrophage; and selecting genes of which expression in macrophage is significantly changed by the Bacillus anthracis lethal toxin, wherein the genes of which expression is significantly changed by the Bacillus anthracis lethal toxin are RPL10A, ARBP, RPL30, RPS3, RPL3, RPS16 and MPRS17.
摘要翻译：目的：提供炭疽杆菌致死毒素对巨噬细胞反应基因的分析方法，该巨噬细胞反应基因可用作生物标志物，因此通过使用生物标志物可以很容易地检测到炭疽杆菌致死毒素的存在。构成：炭疽芽孢杆菌致死毒素对巨噬细胞反应基因的分析方法包括以下步骤：用炭疽杆菌致死毒素处理基因; 测量和比较巨噬细胞处理和不使用炭疽芽孢杆菌致死毒素的基因的表达; 并且选择其中巨噬细胞表达的基因被炭疽芽孢杆菌致死毒素显着改变，其中由炭疽芽孢杆菌致死毒素显着改变的基因是RPL10A，ARBP，RPL30，RPS3，RPL3，RPS16和MPRS17。

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