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1. 发明公开

KR1020050033570A (-)에피갈로카테킨 갈레이트를 포함하는 식품 및 사료 无效
标题翻译：食品和饲料产品包含（ - ）EPIGOCOCATECHIN GALLATE
公开(公告)号：KR1020050033570A
公开(公告)日：2005-04-12
申请号：KR1020050015011
申请日：2005-02-23
申请人： 주식회사 두산 , 가부시키 가이샤 파마푸즈 , 김혜경 , 최강덕 , 정주호 , 임강현
发明人： 정주호 , 최강덕 , 임강현 , 김일수 , 김순애 , 이희제 , 유영민 , 박히준 , 이향숙 , 인창식 , 김혜경 , 서정철 , 김종우
IPC分类号： A23L1/29
CPC分类号： A23L33/00 , A23V2200/322
摘要： A food and feed composition containing (-)epigallocatechin gallate(EGCG) useful as an inhibitor to treat and prevent various diseases associated with the acetylcholine concentration in the body by effectively inhibiting the activity of acetylcholinesterase is provided. Therefore, the composition is useful in treatment and prevention of senile dementia, myasthenia gravis, gastroparesis and glaucoma without toxicity or adverse side effect. The food and feed composition contains (-)epigallocatechin gallate obtained from extraction of green tea. The pharmaceutical preparation containing the EGCG as an effective ingredient is orally administered at a daily dose of 1 to 500mg(preferably 50 to 100mg)/kg body weight one to several times per day. The IC50 value of the EGCG is about 0.13mg/ml(about 0.34mM). For an example, 100mg EGCG is mixed with 68mg corn starch, 90mg lactose, 40mg microcrystalline cellulose and 2mg magnesium stearate to give a tablet containing EGCG.
摘要翻译：提供了含有（ - ）表没食子儿茶素没食子酸酯（EGCG）的食品和饲料组合物，其可用作抑制剂，通过有效抑制乙酰胆碱酯酶的活性来治疗和预防与体内乙酰胆碱浓度相关的各种疾病。因此，该组合物可用于治疗和预防老年痴呆，重症肌无力，胃轻瘫和青光眼，无毒副作用。食物和饲料组合物含有从提取绿茶获得的（ - ）表没食子儿茶素没食子酸酯。含有EGCG作为有效成分的药物以1〜500mg（优选50〜100mg）/ kg体重每天1〜数次的口服给药。 EGCG的IC50值约为0.13mg / ml（约0.34mM）。例如，将100mg EGCG与68mg玉米淀粉，90mg乳糖，40mg微晶纤维素和2mg硬脂酸镁混合，得到含有EGCG的片剂。

2. 发明公开

KR1020030044845A 녹차 추출물을 함유하는 아세틸콜린에스터라제 저해제그리고 이를 포함하는 약학적 제제, 식품 및 사료 无效
标题翻译：乙酰胆碱酯酶抑制剂包含绿茶和药物制剂的提取物，食品和含有它们的产品
公开(公告)号：KR1020030044845A
公开(公告)日：2003-06-09
申请号：KR1020020074922
申请日：2002-11-28
申请人： 정주호 , 최강덕 , 임강현
发明人： 정주호 , 최강덕 , 임강현 , 김일수 , 김순애 , 이희제 , 유영민 , 박히준 , 이향숙 , 인창식 , 김혜경 , 서정철 , 김종우
IPC分类号： A61K36/82 , A61P25/28
摘要： PURPOSE: Provided are an acetylcholinesterase inhibitor comprising extract of green tea and a pharmaceutical preparation, a food product and a feed product containing the same, thereby preventing and treating diseases associated with the concentration of acetylcholine and increasing memory. CONSTITUTION: An acetylcholinesterase inhibitor is characterized by comprising extract of green tea. The extract of green tea is prepared by extracting Camellia sinensis leaves with hot water, cold water, or organic solvents, such as methanol, ethanol, acetone and the like. The extract of green tea contains (-)epicatechin, (-)epicatechin gallate, (-)epigallocatechin, (-)epigallocatechin gallate, caffeine, theanine, vitamins and inorganic matters.
摘要翻译：目的：提供一种包含绿茶提取物和药物制剂，食品和含有它们的饲料产品的乙酰胆碱酯酶抑制剂，从而预防和治疗与乙酰胆碱浓度相关的疾病和增加记忆力。构成：乙酰胆碱酯酶抑制剂的特征在于包含绿茶提取物。绿茶提取物是用热水，冷水或有机溶剂如甲醇，乙醇，丙酮等提取茶叶来制备的。绿茶提取物含有（ - ）表儿茶素，（ - ）表儿茶素没食子酸酯，（ - ）表没食子儿茶素，（ - ）表没食子儿茶素没食子酸酯，咖啡因，茶氨酸，维生素和无机物质。

3. 发明公开

KR1020030039660A 전침을 이용한 관절염 치료방법 无效
标题翻译：使用电针刺治疗神经元的方法
公开(公告)号：KR1020030039660A
公开(公告)日：2003-05-22
申请号：KR1020010070669
申请日：2001-11-14
申请人： 정주호 , 박히준 , 최강덕
发明人： 정주호 , 최강덕 , 박히준 , 김일수 , 김순애 , 이희제 , 유영민 , 임강현 , 이향숙 , 인창식 , 서정철 , 김종우 , 임사비나 , 이혜정
IPC分类号： A61N1/18
摘要： PURPOSE: A method for treating arthritis using an electric acupuncture needle is provided to minimize adverse effect and improve the efficiency of arthritis treatment by applying an acupuncture needle technique in an electrical manner. CONSTITUTION: In a method for treating arthritis by stimulating spots on the body suitable for acupressure by a current applied to a needle using an electric acupuncture needle device electrically connected to a current generator and having a needle receiving a current, the pulse width of the current applied to the needle is 0.1 to 100ms, the frequency of the current is 1 to 10Hz and the strength of the current is 0.1 to 1mA.
摘要翻译：目的：提供一种使用电针治疗关节炎的方法，通过以电气方式应用针灸针技术来减少不良反应并提高关节炎治疗效率。构成：在使用电连接到电流发生器并具有接收电流的针的电针刺装置通过施加到针上的电流刺激适合于指压的身体上的斑点的方法中，电流的脉冲宽度针施加0.1〜100ms，电流频率为1〜10Hz，电流强度为0.1〜1mA。

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