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    • 3. 发明公开
    • 소나무잔나비버섯 추출물을 포함하는 지방축적억제 또는비만 예방 및 치료용 조성물 과 이를 포함하는 약학적 제제및 식품
    • 用于积累抑制或预防和处理脂肪,药物制剂和含有其的功能性食品的组合物
    • KR1020060114725A
    • 2006-11-08
    • KR1020050034804
    • 2005-04-27
    • 김혜경김미자정주호임강현
    • 임강현정주호김혜경김미자김기연
    • A61K36/07A61K36/074A61P3/04
    • A composition for inhibiting fat accumulation or preventing and treating obesity comprising the extract of Fomitopsis pinicola, and a pharmaceutical preparation and functional food product containing the same composition are provided to inhibit differentiation of adipocytes and fat accumulation without side effects, so that the composition is stably administered into patients suffering from diseases associated with obesity. The composition for inhibiting fat accumulation or preventing and treating obesity comprises the extract of Fomitopsis pinicola as an effective component, wherein the extract of Fomitopsis pinicola is prepared by extracting Fomitopsis pinicola with water or organic solvent such as ethyl alcohol. The pharmaceutical preparation or functional food product comprises the extract of Fomitopsis pinicola and pharmaceutically or sitologically acceptable carriers, wherein the dosage of pharmaceutical preparation is 200-400mg per day.
    • 提供一种抑制脂肪蓄积或预防和治疗肥胖的组合物,其包含茯苓提取物,以及含有相同组成的药物制剂和功能性食品,以抑制脂肪细胞的分化和脂肪蓄积而没有副作用,使得组合物稳定 给予患有与肥胖相关的疾病的患者。 用于抑制脂肪蓄积或预防和治疗肥胖症的组合物包括茯苓的提取物作为有效成分,其中通过用水或诸如乙醇的有机溶剂提取罂粟粉来制备茯苓提取物。 药物制剂或功能性食品包括茯苓提取物和药学上可接受的载体,其中药物制剂的剂量为每天200-400mg。
    • 10. 发明公开
    • (-)에피갈로카테킨 갈레이트를 포함하는 식품 및 사료
    • 食品和饲料产品包含( - )EPIGOCOCATECHIN GALLATE
    • KR1020050033570A
    • 2005-04-12
    • KR1020050015011
    • 2005-02-23
    • 주식회사 두산가부시키 가이샤 파마푸즈김혜경최강덕정주호임강현
    • 정주호최강덕임강현김일수김순애이희제유영민박히준이향숙인창식김혜경서정철김종우
    • A23L1/29
    • A23L33/00A23V2200/322
    • A food and feed composition containing (-)epigallocatechin gallate(EGCG) useful as an inhibitor to treat and prevent various diseases associated with the acetylcholine concentration in the body by effectively inhibiting the activity of acetylcholinesterase is provided. Therefore, the composition is useful in treatment and prevention of senile dementia, myasthenia gravis, gastroparesis and glaucoma without toxicity or adverse side effect. The food and feed composition contains (-)epigallocatechin gallate obtained from extraction of green tea. The pharmaceutical preparation containing the EGCG as an effective ingredient is orally administered at a daily dose of 1 to 500mg(preferably 50 to 100mg)/kg body weight one to several times per day. The IC50 value of the EGCG is about 0.13mg/ml(about 0.34mM). For an example, 100mg EGCG is mixed with 68mg corn starch, 90mg lactose, 40mg microcrystalline cellulose and 2mg magnesium stearate to give a tablet containing EGCG.
    • 提供了含有( - )表没食子儿茶素没食子酸酯(EGCG)的食品和饲料组合物,其可用作抑制剂,通过有效抑制乙酰胆碱酯酶的活性来治疗和预防与体内乙酰胆碱浓度相关的各种疾病。 因此,该组合物可用于治疗和预防老年痴呆,重症肌无力,胃轻瘫和青光眼,无毒副作用。 食物和饲料组合物含有从提取绿茶获得的( - )表没食子儿茶素没食子酸酯。 含有EGCG作为有效成分的药物以1〜500mg(优选50〜100mg)/ kg体重每天1〜数次的口服给药。 EGCG的IC50值约为0.13mg / ml(约0.34mM)。 例如,将100mg EGCG与68mg玉米淀粉,90mg乳糖,40mg微晶纤维素和2mg硬脂酸镁混合,得到含有EGCG的片剂。