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    • 1. 发明公开
    • 항염증제 조성물 및 항암제 조성물
    • 作为抗炎药物的组合物和抗癌药物的组合物
    • KR1020100048431A
    • 2010-05-11
    • KR1020080107579
    • 2008-10-31
    • 재단법인 제주테크노파크제주특별자치도
    • 박수영고형범함영민윤원종김길남정용환이욱재
    • A61K35/60A61P29/00
    • A61K35/616A61K39/39558A61K47/6863A61K47/6867Y10S514/886
    • PURPOSE: A composition using Stichopus japonicus Orange extract is provided to suppress generation of NO(nitric oxide), inflammatory cytokines such as TNF-alpha and IL-6, COS-2(clooxygenase-2). CONSTITUTION: An anti-inflammatory composition contains Stichopus japonicus Orange extract as an active ingredient. The Stichopus japonicus Orange extract is isolated using alcohol of 1-5 carbon atoms, acetone, ethylacetate, ether, methylene chloride, chloroform, n-alkane of 5-10 carbon atoms, or mixture thereof. A composition of iNOS inhibition contains the Stichopus japonicus Orange extract as an active ingredient. A composition of COX-2 inhibition contains the Stichopus japonicus Orange extract as an active ingredient. An anti-cancer composition contains the Stichopus japonicus Orange extract as an active ingredient. The composition is a pharmaceutical composition or food composition.
    • 目的:提供使用日本us us橙提取物的组合物,以抑制NO(一氧化氮),炎性细胞因子如TNF-α和IL-6,COS-2(clooxygenase-2)的产生。 构成:抗炎组合物含有日本St us橙提取物作为活性成分。 使用1-5个碳原子的醇,丙酮,乙酸乙酯,乙醚,二氯甲烷,氯仿,5-10个碳原子的正烷烃或其混合物分离日本us us橙提取物。 iNOS抑制剂的组合物含有作为活性成分的日本St us提取物。 COX-2抑制剂的组合物含有作为活性成分的日本St us提取物。 抗癌组合物含有作为活性成分的日本St us提取物。 组合物是药物组合物或食物组合物。
    • 8. 发明公开
    • 율초 또는 붉가시나무 잎 추출물을 이용한 아토피 피부염 개선제 조성물
    • 用于提取人造血管的提取物或提取物的化学成分的组合物
    • KR1020110055940A
    • 2011-05-26
    • KR1020090112570
    • 2009-11-20
    • 재단법인 제주테크노파크
    • 정용환오대주송관필윤원종김길남함영민박수영최한김윤정송정민강세찬정용준김현우
    • A61K36/185A61K36/49A61P17/18A61K8/97
    • PURPOSE: A composition containing Humulus japonicus plant extract and Quercus acuta leaf extract is provided to suppress mast cell degranulation and to treat atopic dermatitis. CONSTITUTION: A composition for treating atopic dermatitis contains Humulus japonicus plant extract and Quercus acuta extract as an active ingredient. The extract is: extract obtained by extracting with alcohol of 1-5 carbon atoms, acetone, hexane, ethyl acetate, chloroform, dichloromethane, water, or mixture solvent; extract obtained using water, ethanol, or mixture solvent thereof; extract of a fraction solvent layer obtained by fractioning the extract with water and hexane, water and dichloromethane, water and ethyl acetate, or water and butanol; or extract obtained by suspending solid extract and fractioning with hexane, dichloromethane, ethyl acetate, and butanol in order. The composition is a cosmetic composition or pharmaceutical composition.
    • 目的:提供含有葎草植物提取物和栎树提取物的组合物,以抑制肥大细胞脱粒并治疗特应性皮炎。 构成:用于治疗特应性皮炎的组合物含有葎草植物提取物和栎属栎提取物作为活性成分。 提取物是:用1-5个碳原子的醇萃取,丙酮,己烷,乙酸乙酯,氯仿,二氯甲烷,水或混合溶剂萃取; 使用水,乙醇或其混合溶剂获得的提取物; 通过用水和己烷,水和二氯甲烷,水和乙酸乙酯或水和丁醇对提取物进行分级获得的级分溶剂层的提取物; 或通过悬浮固体提取物并按顺序用己烷,二氯甲烷,乙酸乙酯和丁醇分馏获得的提取物。 该组合物是化妆品组合物或药物组合物。