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1. 发明公开

KR1020120033535A 홍해삼 추출물을 이용한 항알러지제 조성물 및 항균제 조성물 有权
标题翻译：抗生素组合物和抗菌组合物，使用刺五加橙子提取物
公开(公告)号：KR1020120033535A
公开(公告)日：2012-04-09
申请号：KR1020100095098
申请日：2010-09-30
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 조문제 , 박태균 , 임희경 , 고형범 , 윤원종 , 김길남 , 함영민 , 김동삼
IPC分类号： A61K35/616 , A61K9/14 , A61K9/19
CPC分类号： A61K35/616 , A61K9/14 , A61K9/19
摘要： PURPOSE: An anti-allergic composition and antibacterial composition using Stichopus japonicus Orange extract is provided to suppress degranulation of mast cells and to ensure antibacterial activity. CONSTITUTION: An allergic composition contains Stichopus japonicus Orange extract as an active ingredient. The extract is prepared using water, ethanol, acetone, or mixture thereof. The composition is a pharmaceutical composition and food composition. The antibacterial composition contains Stichopus japonicus Orange extract as an active ingredient. The composition prevents Staphylococcus aureus or Staphylococcus epidermidis.
摘要翻译：目的：提供使用日本us us橙提取物的抗过敏组合物和抗菌组合物，以抑制肥大细胞脱颗粒并确保抗菌活性。构成：过敏组合物含有日本St us橙提取物作为活性成分。提取物用水，乙醇，丙酮或其混合物制备。组合物是药物组合物和食物组合物。抗菌组合物含有日本St us提取物作为活性成分。组合物预防金黄色葡萄球菌或表皮葡萄球菌。

2. 发明公开

KR1020120033534A 홍해삼으로부터의 콜라겐의 분리 방법 无效
标题翻译：从海洋中分离胶原蛋白的方法
公开(公告)号：KR1020120033534A
公开(公告)日：2012-04-09
申请号：KR1020100095097
申请日：2010-09-30
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 조문제 , 박태균 , 임희경 , 고형범 , 윤원종 , 김길남 , 함영민 , 김동삼
IPC分类号： C12P21/06 , C07K1/12 , C07K1/30
CPC分类号： C12P21/06 , C07K1/303 , C07K14/78 , C12Y304/22002 , C12Y304/23001
摘要： PURPOSE: A method for isolating collagen from Stichopus japonicus Orange is provided to ensure high yield and to express fibronectin. CONSTITUTION: A method for isolating collagen from Stichopus japonicus Orange comprises: a step of treating washed Stichopus japonicus Orange with a basic solution to remove non-collagenic proteins; a step of centrifuging and collecting alkali-treated residue; and a step of treating an acidic solution. The basic solution contains sodium hydroxide(NaOH), potassium hydroxide(Ca(OH)_2), magnesium hydroxide(Mg(OH)_2), or mixture thereof. The acidic solution includes citric acid, acetic acid, ascorbic acid, or mixture thereof.
摘要翻译：目的：提供一种从日本斑马鱼中分离胶原蛋白的方法，以确保高产量并表达纤连蛋白。构成：从日本from us橙中分离胶原蛋白的方法包括：用碱性溶液处理洗涤的日本j us橙以去除非胶原蛋白的步骤; 离心收集碱处理残渣的步骤; 以及处理酸性溶液的步骤。碱性溶液含有氢氧化钠（NaOH），氢氧化钾（Ca（OH）2），氢氧化镁（Mg（OH）2））或其混合物。酸性溶液包括柠檬酸，乙酸，抗坏血酸或其混合物。

3. 发明公开

KR1020130042534A 홍해삼으로부터의 콜라겐의 분리 방법 有权
标题翻译：从海洋中分离胶原蛋白的方法
公开(公告)号：KR1020130042534A
公开(公告)日：2013-04-26
申请号：KR1020130038667
申请日：2013-04-09
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 조문제 , 박태균 , 임희경 , 고형범 , 윤원종 , 김길남 , 함영민 , 김동삼
IPC分类号： C07K14/78 , A23J1/04
摘要： PURPOSE: A method for isolating collagen from sea cucumber is provided to ensure excellent wound healing effect by treating red sea cucumber with an alkaline solution, centrifuging, and treating with pepsin. CONSTITUTION: A method for isolating collagen from sea cucumber comprises: a step of treating red sea cucumber with an alkaline solution to remove non-collagenous protein; a step of centrifuging and collecting alkaline-treated residue; and a step of treating the residue with an acid solution and pepsin for 24 hours and 72 hours, respectively.
摘要翻译：目的：提供从海参中分离胶原蛋白的方法，通过用碱性溶液处理红海参，离心分离和用胃蛋白酶处理，确保良好的伤口愈合效果。构成：从海参中分离胶原蛋白的方法包括：用碱性溶液处理红海参以去除非胶原蛋白的步骤; 离心收集碱处理残渣的步骤; 以及分别用酸溶液和胃蛋白酶处理残留物24小时和72小时的步骤。

4. 发明授权

KR101306960B1 홍해삼으로부터의 콜라겐의 분리 방법 有权
标题翻译：从黄瓜中分离胶原蛋白的方法
公开(公告)号：KR101306960B1
公开(公告)日：2013-09-09
申请号：KR1020130038667
申请日：2013-04-09
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 조문제 , 박태균 , 임희경 , 고형범 , 윤원종 , 김길남 , 함영민 , 김동삼
IPC分类号： C07K14/78 , A23J1/04
摘要： 본 발명의 홍해삼으로부터의 콜라겐의 분리 방법을 개시한다. 구체적으로 본 발명의 홍해삼으로부터의 콜라겐의 분리 방법은 (a) 비콜라겐성 단백질의 제거를 위하여 수세한 홍해삼에 염기성 용액을 처리하는 단계, (b) 염기성 용액 처리 후 원심분리하여 알칼리 처리 잔사를 수득하는 단계 및 (c) 수득한 알칼리 처리 잔사에 대하여 산성 용액을 처리하는 단계를 포함하여 구성된다.

5. 发明授权

KR101280431B1 홍해삼 추출물을 이용한 항알러지제 조성물 및 항균제 조성물 有权
标题翻译：抗ergy ergy us us。。。。。。。。。。。。。。。。。。。
公开(公告)号：KR101280431B1
公开(公告)日：2013-06-28
申请号：KR1020100095098
申请日：2010-09-30
申请人： 재단법인 제주테크노파크
发明人： 박수영 , 조문제 , 박태균 , 임희경 , 고형범 , 윤원종 , 김길남 , 함영민 , 김동삼
IPC分类号： A61K35/616 , A61K9/14 , A61K9/19
摘要： 본 발명은 홍해삼 추출물을 이용한 항알러지제 조성물 및 항균제 조성물을 개시한다. 홍해삼 추출물은 비만세포의 탈과립 억제 활성을 보였으며 또한 피부 상재균인 스타필로코커스 아우레우스 및 스타필로코커스 에피더미디스에 항균 활성을 보였다.

6. 发明公开

KR1020100000025A 피부 미백용 조성물 无效
标题翻译：皮肤白化成分
公开(公告)号：KR1020100000025A
公开(公告)日：2010-01-06
申请号：KR1020080059348
申请日：2008-06-24
申请人： 재단법인 제주테크노파크 , (주)설향 , (주)인터케어
发明人： 김범준 , 이홍선 , 박승혜 , 서인수 , 이호상 , 진창현 , 현학송 , 김용성 , 조문제
IPC分类号： A61K8/98 , A61Q19/02
CPC分类号： A61K8/981 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10 , Y10S514/844 , Y10S514/846 , Y10S530/851
摘要： PURPOSE: A composition for skin whitening, which contains pig placental extract is provided to suppress melanogenesis and ensure high skin whitening effect with high safety. CONSTITUTION: A composition for skin whitening contains pig placental extract isolated by ultrasonic wave. The placental extract is: an extract obtained by mixing water, ethanol, or their mixture solvent to pig placental powder and irradiating ultrasonic wave; a powder extract which is removed from placental ground material; an extract of supernatant after centrifuging placental ground material; a powder extract obtained by centrifuging placental ground material and removing solvent from the supernatant; an extract of supernatant obtained by filtering placental ground material and centrifuging; and a powder resultant obtained by filtering placental ground material, removing extract, centrifuging, and removing solvent from supernatant. The composition is a cosmetic composition or pharmaceutical composition.
摘要翻译：目的：提供含有猪胎盘提取物的皮肤美白组合物，以抑制黑色素生成，确保高安全性的高肤色美白效果。构成：皮肤美白组合物含有通过超声波分离的猪胎盘提取物。胎盘提取物是通过将水，乙醇或其混合溶剂与猪胎盘粉末混合并照射超声波获得的提取物; 从胎盘研磨材料中除去的粉末提取物; 离心分离胎盘研磨材料后的上清液提取物; 通过离心胎盘研磨材料并从上清液中除去溶剂获得的粉末提取物; 通过过滤胎盘研磨物质并离心得到的上清液提取物; 通过过滤胎盘磨碎物质，去除提取物，离心分离和从上清液中除去溶剂得到的粉末产物。该组合物是化妆品组合物或药物组合物。

7. 发明公开

KR1020100000026A 돼지 태반 추출물을 이용한 아토피 피부염 개선용 조성물 无效
标题翻译：用PIG PLACENTA改善肛门外膜炎症的组合物
公开(公告)号：KR1020100000026A
公开(公告)日：2010-01-06
申请号：KR1020080059349
申请日：2008-06-24
申请人： 재단법인 제주테크노파크 , (주)설향
发明人： 김범준 , 이홍선 , 박승혜 , 서인수 , 이호상 , 진창현 , 조문제 , 현학송 , 김용성
IPC分类号： A61K35/50 , A61K8/98 , A61K41/00
CPC分类号： A61K35/50 , A61K8/981 , A61K41/0014
摘要： PURPOSE: A composition containing pig placental extract for relieving atopic dermatitis is provided to suppress the expression of MDC(macrophage-derived chemokine) and TARC(thymusand activation-regulated chemokine). CONSTITUTION: A composition for relieving atopic dermatitis contains a pig placental extract by ultra sonic wave, hexane fraction extract of placental extract by water, ethanol, or their mixture solvent or ethylacetate fraction extract of pig placental extract by water, ethanol, or their mixture solvent. The atopic dermatitis is juvenile form atopic dermatitis, young child type atopic dermatitis, adult atopic dermatitis or pregnant women atopic dermatitis. The composition is a pharmaceutical composition or cosmetic composition.
摘要翻译：目的：提供含有用于缓解特应性皮炎的猪胎盘提取物的组合物，以抑制MDC（巨噬细胞来源的趋化因子）和TARC（胸腺和活化调节的趋化因子）的表达。构成：用于缓解特应性皮炎的组合物通过超声波包含猪胎盘提取物，通过水，乙醇或其混合溶剂，通过水，乙醇或其混合溶剂或猪胎盘提取物的乙酸乙酯级分提取物的胎盘提取物的己烷级分提取物。特应性皮炎是青少年特应性皮炎，幼儿型特应性皮炎，成人特应性皮炎或孕妇特应性皮炎。该组合物是药物组合物或化妆品组合物。

8. 发明公开

KR1020090116063A 돼지태반 추출물을 함유하는 조성물 无效
标题翻译：含有SUS家畜提取物的组合物
公开(公告)号：KR1020090116063A
公开(公告)日：2009-11-11
申请号：KR1020080041747
申请日：2008-05-06
申请人： 재단법인 제주테크노파크 , (주)설향
发明人： 조문제 , 임희경 , 서인수 , 진창현 , 유은숙 , 허정식 , 현학송
IPC分类号： A61K35/50 , A61K9/14
CPC分类号： A61K35/50 , A61K9/14
摘要： PURPOSE: A composition containing porcine placenta extract is provided to suppress apoptosis in human fibroblast, caused by hydroperoxide. CONSTITUTION: A pharmaceutical composition for anti-oxidation, anti-inflammation or atopic dermatitis treatment contains porcine placenta extract as an active ingredient. A method for preparing the porcine placenta extract comprises: a step of freeze-drying porcine placenta then pulverizing; a step of extracting pulverized placenta using phosphate buffer, Tris buffer or water through ultrasonic wave; and a step of centrifuging then freeze-drying to obtain powder.
摘要翻译：目的：提供含有猪胎盘提取物的组合物，以抑制由氢过氧化物引起的人成纤维细胞凋亡。构成：用于抗氧化，抗炎或特应性皮炎治疗的药物组合物含有猪胎盘提取物作为活性成分。制备猪胎盘提取物的方法包括：将猪胎盘冷冻干燥的步骤，然后粉碎; 使用磷酸盐缓冲液，Tris缓冲液或水通过超声波提取粉碎的胎盘的步骤; 离心后冷冻干燥，得到粉末的步骤。

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