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    • 2. 发明公开
    • 씀바귀 추출물을 유효 성분으로 함유하는 피부질환의 예방과 치료를 위한 조성물
    • 包含IXERIS DENTATA NAKAI用于治疗或预防皮肤疾病的药物的药物
    • KR1020120136460A
    • 2012-12-20
    • KR1020110055403
    • 2011-06-09
    • 원광대학교산학협력단
    • 홍승헌정동명엄재영정현주권동렬전용덕
    • A61K36/28A61P17/00
    • PURPOSE: A composition containing Ixeris dentata Nakai extract for preventing and treating dermatitis is provided to prevent skin barrier damage and to suppress hypersensitivity of IL-1 beta. CONSTITUTION: A pharmaceutical composition for preventing and treating dermatitis contains Ixeris dentata Nakai extract as an active ingredient. The extract reduces IgE and IL-1beta amount in blood. An agent for preventing and treating dermatitis contains the extract as an active ingredient. The agent is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, aerosol, suppository, or sterilized injection solution by adding pharmaceutically acceptable carriers, excipients, or diluents. A health functional food for preventing and treating dermatitis contains the extract as an active ingredient and sitologically acceptable food additives.
    • 目的:提供一种含有防治皮肤炎的益母草Nakai提取物的组合物,以防止皮肤屏障损伤并抑制IL-1β的超敏反应。 构成:用于预防和治疗皮炎的药物组合物含有益母草提取物作为活性成分。 提取物可降低血液中的IgE和IL-1β量。 用于预防和治疗皮炎的药剂含有提取物作为活性成分。 药剂通过加入药学上可接受的载体,赋形剂或稀释剂,以粉末,颗粒,片剂,胶囊,悬浮液,乳剂,糖浆,气雾剂,栓剂或灭菌注射液的形式制造。 用于预防和治疗皮炎的保健功能食品含有作为活性成分的提取物和可接受的食品添加剂。
    • 4. 发明公开
    • 커큐민을 유효성분으로 포함하는 지방간 질환의 치료 또는 예방용 조성물
    • 用于治疗和预防含有CURCUMIN作为活性成分的脂肪肝疾病的药物组合物
    • KR1020140104090A
    • 2014-08-28
    • KR1020130017751
    • 2013-02-20
    • 원광대학교산학협력단
    • 권동렬홍승헌김윤경이영미이은주강옥화김성배
    • A61K31/12A61P1/16A61P25/32
    • The present invention relates to a pharmaceutical composition including curcumin as an active ingredient for treating or preventing non-alcoholic fatty liver diseases. The non-alcoholic fatty liver diseases may be obese fatty liver diseases or diabetic fatty liver diseases. Moreover, the present invention relates to a food composition including curcumin as an active ingredient for alleviating or preventing non-alcoholic fatty liver diseases. The food composition may be a health functional food composition. The curcumin is derived from an edible plant so as not to cause side effects or problems related to stability, effectively controls the expression of fatty acid synthase (FAS) and fatty acid biosynthesis regulatory transcription factors (SREBP-1), remarkably promotes the expression of PPAR-alphs, and has an excellent function of reinforcing AMP-activated protein kinase activities. Accordingly, the curcumin has excellent effects in treating, preventing, or alleviating non-alcoholic fatty liver caused by the accumulation of fat in liver cells so that the curcumin can be used as a medical composition for treating or preventing fatty liver diseases or a food composition for alleviating or preventing fatty liver diseases and also used in improving liver functions or protecting the liver.
    • 本发明涉及包含姜黄素作为治疗或预防非酒精性脂肪性肝病的活性成分的药物组合物。 非酒精性脂肪肝疾病可能是肥胖性脂肪性肝病或糖尿病性脂肪性肝病。 此外,本发明涉及包含姜黄素作为缓和或防止非酒精性脂肪肝疾病的活性成分的食品组合物。 食物组合物可以是健康功能食品组合物。 姜黄素来自可食用植物,不会引起副作用或与稳定有关的问题,有效控制脂肪酸合酶(FAS)和脂肪酸生物合成调控转录因子(SREBP-1)的表达,显着促进了 PPAR-alphs,并且具有增强AMP活化蛋白激酶活性的极好功能。 因此,姜黄素在治疗,预防或缓解由肝细胞中的脂肪积累引起的非酒精性脂肪肝方面具有优异的效果,因此姜黄素可用作治疗或预防脂肪肝疾病或食物组合物的医药组合物 用于减轻或预防脂肪肝疾病,并用于改善肝功能或保护肝脏。