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    • 6. 发明公开
    • 퓨트레신 생산능이 향상된 재조합 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법
    • 具有增强聚氨酯生产能力的微生物和使用它们生产聚氨酯的方法
    • KR1020130086010A
    • 2013-07-30
    • KR1020130006707
    • 2013-01-21
    • 씨제이제일제당 (주)
    • 이경민김선혜엄혜원강민선최수진정희경전성후리홍선곽원식이종호양영렬
    • C12N1/21C12N15/60C12N15/74C12P13/00
    • C12N15/77C12N15/52C12P13/001
    • PURPOSE: Corynebacterium microorganisms with improved productivity for putrescine are provided to recombine corynebacterium microorganisms in order to lower the activation of NCgl0101 than internal activation, thereby producing putrescine with high yield and being widely used for the production of effective putrescine. CONSTITUTION: Corynebacterium microorganisms with improved productivity for putrescine are produced by lowering or removing the activation of protein having the amino acid sequence represented by sequence number 17 or the sequence number 19 in Corynebacterium microorganisms which are recombined in order to produce putrescine. Putrescine manufacturing method comprises; a step of cultivating Corynebacterium microorganisms in which the activation of protein having the amino acid sequence represented by sequence number 17 or the sequence number 19 is removed or lower than internal activation and the productivity for putrescine is increased; and a step separating the putrescine from the culture material obtained in the previous step. The Corynebacterium microorganism is Corynebacterium glutamicum.
    • 目的:提供腐胺生产力的棒状杆菌微生物以重组棒状杆菌微生物,以降低NCgl0101的活化,而不是内部活化,从而以高产率生产腐胺,广泛用于生产有效的腐胺。 构成:通过降低或除去重组以产生腐胺的棒状杆菌属微生物中由序列号17或序列号19表示的氨基酸序列的蛋白质的活化而产生具有提高腐胺生产力的棒状杆菌微生物。 腐胺制造方法包括: 培养其中具有由序列号17或序列号19表示的氨基酸序列的蛋白质的活化被去除或低于内部活化并且腐胺的生产力增加的棒状杆菌微生物的步骤; 以及将腐胺与前一步骤中获得的培养物质分离的步骤。 棒状杆菌属微生物是谷氨酸棒杆菌。