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    • 1. 发明公开
    • 임신 합병증의 진단 및 치료에 유용한 핵산 및 폴리펩티드
    • 用于诊断和治疗孕妇综合症的核酸和多肽
    • KR1020070092737A
    • 2007-09-13
    • KR1020077016078
    • 2005-12-15
    • 베스 이스라엘 데코니스 메디칼 센터
    • 카루만치,에스.,아난트수카트메,비카스,피.
    • C12Q1/00
    • G01N33/689C12Q1/6883C12Q2600/158G01N33/6893G01N2800/321G01N2800/368
    • Disclosed herein are methods for diagnosing or treating pregnancy related hypertensive disorders that include the use of a polypeptide or a nucleic acid encoding a polypeptide selected from the following: follistatin related protein, interleukin 8, inhibin A, VEGF-C, angiogenin, beta fertilin, hypothetical protein, leukocyte associated Ig-like receptor secreted protein, erythroid differentiation protein, adipogenesis inhibitory factor, corticotropin releasing factor binding protein, alpha-1-anti-chymotrypsin, insulin-like growth factor binding protein-5, CD33L, cytokine receptor like factor 1, platelet derived endothelial growth factor, lysyl hydroxylase isoform 2, stanniocalcin precursor, secreted frizzled related protein, galectin-3, alpha defensin, ADAM-TS3, cholecystokinin precursor, interferon stimulated T-cell alpha chemoattractant precursor, azurocidin, sperminine oxidase, UDP glycosyltransferase 2 family polypeptide B28, neurotrophic tyrosine kinase receptor 2, neutral endopeptidase, CDC28 protein kinase regulatory subunit 2, beta glucosidase, lanosterol synthase, calcium/calmodulin-dependent serine protein kinase, estrogen receptor-alternatively spliced transcript H, chemokine (CX3C motif) receptor 1, tyrosinase-related protein 1, hydoxy-delta-5-steroid dehyrogenase, dihydropyramidinase-like-4, and cytochrome P450-family 11.
    • 本文公开了用于诊断或治疗怀孕相关性高血压病症的方法,其包括使用多肽或编码选自以下的多肽的核酸:卵泡抑素相关蛋白,白细胞介素8,抑制素A,VEGF-C,血管生成素, 假性蛋白,白细胞相关的Ig样受体分泌蛋白,红细胞分化蛋白,脂肪形成抑制因子,促肾上腺皮质激素释放因子结合蛋白,α-1-抗胰凝乳蛋白酶,胰岛素样生长因子结合蛋白-5,CD33L,细胞因子受体样因子 1,血小板衍生的内皮生长因子,赖氨酰羟化酶同种型2,斯诺钙钙前体,分泌性卷曲相关蛋白,半乳凝素-3,α-防御素,ADAM-TS3,缩胆囊素前体,干扰素刺激的T细胞α化学引诱物前体,azurocidin,精氨酸氧化酶,UDP 糖基转移酶2家族多肽B28,神经营养性酪氨酸激酶受体2,中性endopept 雌激素受体 - 可变剪接的转录物H,趋化因子(CX3C基序)受体1,酪氨酸酶相关蛋白1,羟基-δ-蛋白激酶调控亚单位2,β-葡糖苷酶,羊毛甾醇合酶,钙/钙调蛋白依赖性丝氨酸蛋白激酶, 5-类固醇脱氢酶,二氢吡喃脒酶-4和细胞色素P450-家族11。