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1. 发明授权

KR101343820B1 경막결정화를 이용한 홍삼농축액의 고순도 분리 정제방법 및 이를 이용하여 고순도의 총진세노사이드 함량을 정량화하는 홍삼농축액의 제조방법 有权
标题翻译：用于控制红葡萄酒提取物中总的甘氨酸含量的层结晶技术和使用其的量化红葡萄提取物的制造技术
公开(公告)号：KR101343820B1
公开(公告)日：2013-12-20
申请号：KR1020130037330
申请日：2013-04-05
申请人： 대동고려삼 주식회사
发明人： 김성일 , 최성근 , 박노영
IPC分类号： A23L19/00 , A23L2/38
CPC分类号： A23L2/38 , A23L19/00 , A23V2002/00 , A23V2250/2124 , A61K36/258
摘要： The present invention relates to a method for isolating and purifying high purity red ginseng concentrate by a first and a second layer crystallization and a manufacturing method for quantifying the contents of 11 kinds of ginsenosides. The present invention comprises: a first layer crystallization step for mixing the red ginseng concentrate and ethanol, then layer crystallizing primarily; and a second layer crystallization step for mixing a first acquisition and ethanol again, then layer crystallizing secondarily. The present invention provides a technique for isolating and purifying total ginsenosides from the red ginseng concentrate effectively which has an effect in cutting the unit cost of production and which upgrades the specifications of red ginseng concentrate products using high purity total ginsenosides, thereby leading the world in various high value red ginseng products market. Especially, development of the high purity total ginsenosides ensures production of the red ginseng concentrate products containing quantified total ginsenosides, thereby providing high quality products in the future market of raw material for the medicine. [Reference numerals] (AA) Red ginseng concentrate;(BB,EE) 95% Ethanol;(CC) First layer crystallization;(DD) Purity of total ginsenosides: 8.5 to 92 weight%;(FF) Mixing;(GG) First crystallized mixture;(HH) Second crystallized mixture;(II) Quantitative standard red ginseng concentrate;(JJ) Second layer crystallization;(KK) Purity of total ginsenosides: 72 to 98 weight%;(LL) High purity total ginsenosides
摘要翻译：本发明涉及通过第一层和第二层结晶分离纯化高纯度红参浓缩物的方法和用于量化11种人参皂甙含量的制造方法。本发明包括：第一层结晶步骤，用于混合红参浓缩物和乙醇，然后主要层结晶; 以及第二层结晶步骤，用于再次混合第一次采集和乙醇，然后二次层析结晶。本发明提供了一种从人参浓缩物中有效分离和纯化人参皂苷的技术，其具有降低生产单位成本的效果，并且使用高纯度总人参皂苷来提升红参浓缩物产品的规格，从而引领世界各种高价值红参产品市场。特别是高纯度人参皂苷的开发，确保生产含人参皂甙量的红参浓缩物，从而在未来市场上提供优质的产品。（AA）红参浓缩物（BB，EE）95％乙醇;（CC）第一层结晶;（DD）总人参皂苷的纯度：8.5〜92重量％;（FF）混合;（GG）结晶混合物;（HH）第二结晶混合物;（II）定量标准红参浓缩物;（JJ）第二层结晶;（KK）总人参皂苷的纯度：72〜98重量％;（LL）高纯度总人参皂苷

2. 发明授权

KR101343819B1 11종의 진세노사이드 성분을 유효성분으로 하는 홍삼농축액 분말, 비타민 및 미네랄로 조성된 항스트레스, 항고지혈증 및 항비만용 조성물 및 건강기능식품 有权
标题翻译：使用红色金松提取粉，维生素和矿物质以及健康功能食品改善抗生素，抗血小板药和抗生素控制的组合物
公开(公告)号：KR101343819B1
公开(公告)日：2013-12-20
申请号：KR1020130037319
申请日：2013-04-05
申请人： 대동고려삼 주식회사
发明人： 김성일 , 최성근 , 이창순 , 박노영 , 박기태 , 김도연 , 유영춘
IPC分类号： A23L19/00 , A23L33/15 , A23L2/38 , A23L2/52
CPC分类号： A23L19/00 , A23L2/38 , A23L2/52 , A23L33/15 , A23V2002/00 , A23V2200/3262 , A23V2250/2124 , A61K36/258
摘要： A composition for anti-stress, anti-hyperlipidemia, and anti-obesity in the present invention comprises red ginseng extract powder containing eleven kinds of ginsenosides as active ingredients, vitamins, and minerals at a certain ratio. The composition according to the present invention comprises 20-30 weight% of the red ginseng extract powder containing eleven kinds of ginsenosides as active ingredients, 55-67 weight% of the vitamins, and 2.5-14 weight% of the minerals and the eleven kinds of ginsenoides comprises Rg1, Re, Rf, Rb1, Rg2, Rc, Rb2, Rb3, Rd, Rg3, and Rh2. The present invention provides the composition for anti-stress, anti-hyperlipidemia, and anti-obesity using the eleven kinds of ginsenosides, active ingredients of ginseng, as a health functional food minimizing side effects and having effects for preventing and treating diseases related to stress, hyperlipidemia, and obesity. [Reference numerals] (A) 6.5% of quantified red ginseng concentrate powder;(B) 5% of quantified red ginseng concentrate
摘要翻译：本发明的抗应激，抗高脂血症，抗肥胖的组合物，含有以人为参考的十一种人参皂甙作为活性成分的红参提取物，维生素，矿物质。根据本发明的组合物包含20-30重量％的红参提取物粉末，其含有十一种人参皂甙作为活性成分，55-67重量％的维生素和2.5-14重量％的矿物质和十一种人参皂苷包括Rg1，Re，Rf，Rb1，Rg2，Rc，Rb2，Rb3，Rd，Rg3和Rh2。本发明提供了使用十一种人参皂苷，人参活性成分作为健康功能食品，使副作用最小化并具有预防和治疗与应激相关的疾病的作用的抗应激，抗高脂血症和抗肥胖的组合物，高脂血症和肥胖症。 [参考数字]（A）定量红参浓缩粉6.5％;（B）5％定量红参浓缩粉

3. 发明授权

KR101106487B1 진세노사이드 Ｒｇ3 및 Ｒｈ2가 강화된 홍삼농축액 제조방법 有权
标题翻译：用甘氨酸RG3和RH2制备红银杏提取物的方法
公开(公告)号：KR101106487B1
公开(公告)日：2012-01-20
申请号：KR1020110072609
申请日：2011-07-21
申请人： 대동고려삼 주식회사
发明人： 최성근 , 김성일 , 박노영
IPC分类号： A23L33/00 , A23L19/00 , A23L2/38
CPC分类号： A61K36/258 , A23L33/105 , A23V2002/00 , A61K2236/00 , A23V2200/324 , A23V2250/2124 , A23V2200/308 , A23V2200/326
摘要： PURPOSE: A producing method of a red ginseng concentrate with enriched ginsenoside-RG3 and RG2 is provided to offer the improved conversion ratio of specific saponin using simplified producing processes. CONSTITUTION: A producing method of a red ginseng concentrate with enriched ginsenoside-RG3 and RG2 comprises the following steps: adding 1-5% of malic acid, tartaric acid, or succinic acid into a raw red ginseng extract; and hydrolyzing the mixture at 90-95 deg C for 3-48 hours. The raw red ginseng extract is obtained by extracting dried red ginseng using an extracto and alcohol.
摘要翻译：目的：提供浓缩人参皂苷-RG3和RG2的红参浓缩物的生产方法，通过简化生产工艺提供特定皂苷的转化率提高。构成：人参浓缩富含人参皂甙-RG3和RG2的红参浓缩物的制备方法如下：将1％〜5％的苹果酸，酒石酸或琥珀酸加入到人参提取物中; 并在90-95℃水解该混合物3-48小时。生红花提取物是通过萃取和酒精提取干红参获得的。

4. 发明授权

KR101439102B1 진생베리로부터 진생베리 추출농축액을 효율적으로 제조하는 신규한 제조방법 有权
标题翻译：金辛提取和浓缩有效制造的新工艺技术
公开(公告)号：KR101439102B1
公开(公告)日：2014-09-12
申请号：KR1020130157047
申请日：2013-12-17
申请人： 대동고려삼 주식회사
发明人： 김성일 , 박노영 , 공병만 , 최성근
IPC分类号： A23L19/00 , A23L2/02 , A23L2/04
CPC分类号： A23L2/04 , A23L2/385 , A23L19/00
摘要： The present invention relates to a method for producing ginseng berry extracted and concentrated liquid, wherein ginsenoside Re and Rd which are the standard of ginseng berry`s pharmacological active ingredients are not destroyed, and a process yield is increased. A liquor solution which is an extraction solvent containing ginseng berries which are raw ingredients is firstly extracted while an inert gas is injected therein, and concentrated so that first extracted and concentrated liquid and a first extracted residue are collected. The first extracted residue is secondly extracted and concentrated using alpha-amylase, which is a starch degrading enzyme, and ultrasonic wave injection, so that second extracted and concentrated liquid is collected. A final product is produced by mixing and concentrating the first and second extracted and concentrated liquids. In the present invention, extraction is performed while the ginsenoside Re and Rd contained in the ginseng berries are not destroyed, and medicinal effects of the ginseng berries are conserved. A production procedure is simple, and a production unit cost can be reduced, so that the same is highly competitive in a health functional food ingredient, medical product ingredient, or cosmetic ingredient market, and a consumer can be provided with a high quality and low price product.
摘要翻译：本发明涉及一种生产人参浆果提取浓缩液的方法，其中作为人参浆果药理活性成分标准的人参皂甙Re和Rd不被破坏，加工收率提高。首先在注入惰性气体的同时提取作为原料的作为含有人参浆果的提取溶剂的液体溶液，并浓缩，从而收集第一次萃取浓缩液体和第一次提取的残留物。将第一次提取的残余物用淀粉降解酶α-淀粉酶和超声波注射法第二次提取和浓缩，从而收集第二次提取的浓缩液体。通过混合和浓缩第一和第二提取浓缩液体来生产最终产品。在本发明中，在人参果实中含有的人参皂苷Re和Rd不被破坏的同时进行提取，并且保存了人参果实的药效。生产过程简单，生产单位成本可以降低，在健康功能食品成分，医药产品成分或化妆品成分市场上具有很高的竞争力，消费者可以获得高品质，低成本价格产品。

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