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    • 4. 发明公开
    • 세포사 억제 및 항산화 활성을 갖는 감국 추출물을함유하는 뇌질환의 예방 및 치료용 약학조성물
    • 包含抗炎和抗氧化活性的枸杞子提取物的药物组合物,用于预防和治疗神经损伤性疾病
    • KR1020090112133A
    • 2009-10-28
    • KR1020080037840
    • 2008-04-23
    • 건국대학교 산학협력단
    • 최동국김인수황금희최현장이강용
    • A61K36/28A61P25/28
    • PURPOSE: A pharmaceutical composition containing Chrysanthemum indicum extract is provided to protect nerves and use as a medical product for prevent and treating brain diseases such as Parkison disease and Alzheimer. CONSTITUTION: A method for producing a pharmaceutical composition for preventing and treating brain disease containing Chrysanthemum indicum extract with apoptosis and antioxidation activity comprises: a step of pulverizing dried Chrysanthemum indicum; a step of mixing 8-18 times volume of water, polar solvent of C1-C4 alcohol or their mixture solvent pulverized Chrysanthemum indicum in mixture ratio of 1:0.1-1:10; a step of extracting for 2 to 4 hours through hot-water extraction, cold water extraction, flux extraction or ultrasonic wave extraction; and a step of concentrating supernatant.
    • 目的:提供含有菊花提取物的药物组合物,以保护神经,并用作预防和治疗脑疾病如帕金森病和阿尔茨海默病的医疗产品。 构成:用于预防和治疗含有菊花提取物的脑病的药物组合物的凋亡和抗氧化活性的方法包括:将干燥的菊花粉碎的步骤; 混合8-18倍体积的水,C1-C4醇的极性溶剂或它们的混合溶剂粉碎菊花的混合比例为1:0.1-1:10的步骤; 通过热水提取,冷水萃取,助熔剂提取或超声波提取提取2〜4小时的步骤; 和浓缩上清液的步骤。