专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

KR1020110042837A 1,8-옥탄디올을 함유하는 저자극성 피부 외용제 조성물 有权
标题翻译：外用于含有1,8-十八烷醇的皮肤的低刺激性组合物
公开(公告)号：KR1020110042837A
公开(公告)日：2011-04-27
申请号：KR1020090099686
申请日：2009-10-20
申请人： (주)아모레퍼시픽
发明人： 이은영 , 조선아 , 윤유나 , 한진태 , 안수선 , 이태룡
IPC分类号： A61K8/34 , A61Q19/00
CPC分类号： A61K8/345 , A61K2800/30 , A61K2800/72 , A61Q19/00
摘要： PURPOSE: An external use skin composition containing 1,8-octandiol is provided to ensure excellent usage, safety, and preservation and to be applied to cosmetic field. CONSTITUTION: An external use skin composition of low irritation contains 1,8-octandiol without separate preservative ingredients. A cosmetic composition contains the external use skin composition. The cosmetic composition is manufactured in the form of lotion, astringent, eye cream, nutrition cream, massage cream, cleansing cream, cleansing foam, cleansing water, powder, essence, or pack.
摘要翻译：目的：提供含有1,8-辛二醇的外用皮肤组合物，以确保优异的使用，安全性和保存性，并适用于化妆品领域。构成：低刺激的外用皮肤组合物含有1,8-辛二醇，没有单独的防腐成分。化妆品组合物含有外用皮肤组合物。化妆品组合物以洗剂，收敛剂，眼霜，营养霜，按摩膏，清洁霜，清洁泡沫，清洁水，粉末，精华或包装的形式制成。

2. 发明公开

KR1020100046668A 피부 자극감 완화 효과 평가방법 无效
标题翻译：评估皮肤感觉刺激减轻效果的方法
公开(公告)号：KR1020100046668A
公开(公告)日：2010-05-07
申请号：KR1020080105619
申请日：2008-10-28
申请人： (주)아모레퍼시픽
发明人： 이은영 , 안수선 , 김서영 , 조선아 , 이태룡
IPC分类号： A61B5/05 , A61B10/00
摘要： PURPOSE: An evaluation method is provided to objectively measure the relief effect of sensory skin irritation by quantifying the relief effect of sensory skin irritation about various anti-irritants through the change of concrete threshold. CONSTITUTION: A sensory skin irritation relief effect evaluation method comprises a step of measuring the change of a threshold before and after spreading an anti-irritant to a stimulus applied to the skin sensory nerve. The evaluation method quantitatively measures the change of the threshold by using a device. The evaluation method measures the change of the threshold value about a stimulus applied to at least one skin sensory nerve which is selected in a group which includes Aα, Aβ, Aδ, and C-fiber type. The evaluation method measures the change of the threshold value about a stimulus which is applied to the skin sensory nerve of Aδ or C-fiber type.
摘要翻译：目的：通过改变混凝土阈值，量化消除各种抗刺激剂对皮肤刺激的缓解作用，提供评估方法，客观地测量感觉皮肤刺激的缓解作用。构成：感官皮肤刺激缓解效果评估方法包括测量在将抗刺激剂涂抹于皮肤感觉神经的刺激之前和之后的阈值变化的步骤。评价方法通过使用装置定量地测量阈值的变化。评估方法测量关于施加到包括Aα，Aβ，Aδ和C纤维类型的组中选择的至少一种皮肤感觉神经的刺激的阈值变化。评估方法测量施加于Aδ或C纤维类型的皮肤感觉神经的刺激的阈值变化。

3. 发明公开

KR1020080050786A 글루코실스핑고신 또는 그 유도체의 용도 无效
标题翻译：葡萄球菌素或其衍生物的使用
公开(公告)号：KR1020080050786A
公开(公告)日：2008-06-10
申请号：KR1020060121508
申请日：2006-12-04
申请人： (주)아모레퍼시픽
发明人： 김형준 , 김대권 , 성기사 , 김혁 , 조선아 , 김광미 , 노민수 , 이창훈 , 김정주
IPC分类号： A61K31/133
摘要： A method for inducing itch and a method for screening an itch inhibiting material using glucosylsphingosine are provided to be useful for studying and understanding the itch, thereby being very usefully used for developing a therapeutic agent for the itch and evaluating the effect of a medicine. A method for inducing itch comprises a step of administering at least one compound selected from the group consisting of glucosylsphingosine and a derivative thereof into an animal except human. A method for screening an itch inhibiting material comprises the steps of: (a) administering an itch inhibition candidate material to an animal where the itch is induced by administering at least one compound selected from the group consisting of the glucosylsphingosine and the derivative thereof; and (b) counting a number when the animal scratches. A method for evaluating the itch inhibition effect comprises the steps of: (a) administering an itch inhibition material to an animal where the itch is induced by administering at least one compound selected from the group consisting of the glucosylsphingosine and the derivative thereof; and (b) counting a number when the animal scratches. A composition for inducing itch comprises at least one compound selected from the group consisting of the glucosylsphingosine and the derivative thereof as an effective ingredient.
摘要翻译：提供诱导瘙痒的方法和使用葡糖基鞘氨醇来筛选瘙痒抑制物质的方法，可用于研究和理解瘙痒，从而非常有用地用于开发瘙痒治疗剂并评估药物的效果。诱导瘙痒的方法包括向除人之外的动物中施用至少一种选自葡糖基鞘氨醇及其衍生物的化合物的步骤。筛选瘙痒抑制物质的方法包括以下步骤：（a）通过施用至少一种选自葡糖基鞘氨醇及其衍生物的化合物，向瘙痒诱导的动物施用瘙痒抑制候选物质; 和（b）当动物划伤时计数。评估瘙痒抑制效果的方法包括以下步骤：（a）向通过施用至少一种选自葡糖基鞘氨醇及其衍生物的化合物诱导瘙痒的动物施用瘙痒抑制物质; 和（b）当动物划伤时计数。用于诱导瘙痒的组合物包含至少一种选自葡糖基鞘氨醇及其衍生物的化合物作为有效成分。

4. 发明公开

KR1020080034575A ＣＣＬ27/ＣＴＡＣＫ의 발현을 억제시키는 방법 有权
标题翻译：抑制CCL27 / CTACK表达的方法
公开(公告)号：KR1020080034575A
公开(公告)日：2008-04-22
申请号：KR1020060100703
申请日：2006-10-17
申请人： (주)아모레퍼시픽
发明人： 성기사 , 김형준 , 김혁 , 김대권 , 조선아 , 김광미 , 이창훈 , 김정주
IPC分类号： A61K31/047 , A61K31/13
CPC分类号： A61K31/047
摘要： A method for inhibiting the expression of CCL27/CTACK(Cutaneous T-cell-attracting chemokine) is provided to regulate SPC(sphingosylphosphorylcholine) inducing expression of CCL27/CTACK, so that the method is useful for prevention and treatment of diseases associated with overexpression of CCL27/CTACK including atopic dermatitis, psoriasis and inflammatory skin disease. The expression of CCL27/CTACK is inhibited by administering an effective amount of sphingosylphosphorylcholine regulator capable of inhibiting activity of SPC or competing with the mechanism of SPC inducing overexpression of CCL27/CTACK to a mammal requiring the expression reduction of CCL27/CTACK. A method for screening the SPC regulator comprises the steps of: (1) treating a testing cell such as keratinocyte with 2-10 muM of SPC or its derivatives to induce overexpression of CCL27/CTACK; and (2) treating the overexpression of CCL27/CTACK-induced cell with a candidate material and measuring the expression inhibition of CCL27/CTACK. Further, the mammal has an atopic dermatitis or psoriasis.
摘要翻译：提供抑制CCL27 / CTACK（皮肤T细胞吸引趋化因子）表达的方法，以调节诱导CCL27 / CTACK表达的SPC（鞘氨醇磷酰胆碱），从而该方法可用于预防和治疗与过表达相关的疾病 CCL27 / CTACK包括特应性皮炎，牛皮癣和炎性皮肤病。通过施用有效量的能够抑制SPC活性或与诱导CCL27 / CTACK过表达的SPC的机制竞争需要CCL27 / CTACK表达降低的哺乳动物，CCL27 / CTACK的表达被抑制。用于筛选SPC调节剂的方法包括以下步骤：（1）用2-10μM的SPC或其衍生物处理测试细胞如角质细胞，以诱导CCL27 / CTACK的过度表达; 和（2）用候选物质治疗CCL27 / CTACK诱导的细胞的过度表达，并测量CCL27 / CTACK的表达抑制。此外，哺乳动物具有特应性皮炎或牛皮癣。

5. 发明公开

KR1020070107961A 생약 추출물을 함유하는 가려움증 억제 및 완화용 조성물 有权
标题翻译：组合物包含原发性药物提取物显示抗病毒作用
公开(公告)号：KR1020070107961A
公开(公告)日：2007-11-08
申请号：KR1020060040588
申请日：2006-05-04
申请人： (주)아모레퍼시픽
发明人： 김대권 , 성대석 , 김광미 , 김형준 , 한지숙 , 김혁 , 성기사 , 박종희 , 조선아 , 이창훈 , 김정주
IPC分类号： A61K36/9068 , A61K36/754
CPC分类号： A61K36/00 , A61K8/97 , A61K9/00 , A61K36/754 , A61K36/9062 , A61K36/9068 , A61K2236/33 , A61Q19/00 , A61Q19/005 , Y10S514/857
摘要： A composition comprising extracts of crude drugs is provided to suppress and relieve itching caused by inflammatory and atopic dermatitis without side effects such as toxicity and skin irritation. A composition for suppressing and relieving itching comprises 0.1-10 wt.% of the extracts of Zingiber officinale Rosc., Evodia officinalis and Alpinia katsumadai Hayata which are prepared by extracting them with water, C1-C4 lower alcohol or a mixed solvent thereof. The daily dosage of crude drug extracts is 0.001-100 mg/kg, preferably 0.1-30 mg/kg and the composition is a pharmaceutical composition having a formulation selected from ointment, plaster, lotion and liniment, or a cosmetic composition having a formulation selected from skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutrition lotion, massage cream, nutrition cream, moisture cream, hand cream, foundation, essence, nutrition essence, pack, soap, cleansing foam, cleansing lotion, cleansing cream, body lotion and body cleanser.
摘要翻译：提供包含生药提取物的组合物以抑制和缓解由炎性和特应性皮炎引起的瘙痒，而没有副作用，例如毒性和皮肤刺激。用于抑制和缓解瘙痒的组合物包括通过用水，C1-C4低级醇或其混合溶剂提取它们制备的姜黄提取物的0.1-10重量％的提取物。生药提取物的日剂量为0.001-100mg / kg，优选0.1-30mg / kg，并且组合物是具有选自软膏，石膏，洗剂和搽剂的制剂的药物组合物或具有选择的制剂的化妆品组合物从皮肤洗剂，皮肤柔肤剂，皮肤调色剂，收敛剂，乳液，乳液，滋润乳液，营养乳液，按摩霜，营养霜，保湿霜，护手霜，粉底，精华，营养精华，包装，肥皂，清洁泡沫，清洁洗剂，清洁霜，身体乳液和身体清洁剂。

6. 发明授权

KR102224350B1 피부 자극 완화제 및 이를 포함하는 피부 미백용 화장료 조성물 有权
公开(公告)号：KR102224350B1
公开(公告)日：2021-03-09
申请号：KR1020140072766
申请日：2014-06-16
申请人： (주)아모레퍼시픽
发明人： 유세진 , 조선아
IPC分类号： A61K8/9789 , A61K8/67 , A61Q19/02 , A61K8/63
摘要： 본발명은녹차나무뿌리추출물을유효성분으로함유하는피부자극완화제및 이를포함하는피부미백용화장료조성물에관한것이다.

7. 发明公开

KR1020160051274A 효소 처리된 차나무 뿌리 유래 사포닌 분획물을 함유하는 피부 외용제 조성물 审中-实审
标题翻译：含有从CAMELLIA SINENSIS基因衍生的酶处理柚子的皮肤的外用组合物
公开(公告)号：KR1020160051274A
公开(公告)日：2016-05-11
申请号：KR1020140150909
申请日：2014-11-03
申请人： (주)아모레퍼시픽
发明人： 유세진 , 조선아
IPC分类号： A61K8/97 , A61K36/82 , A61P17/00
CPC分类号： A61K36/82 , A61K8/66 , A61K8/9789 , A61Q19/00 , A61Q19/008
摘要： 본발명은차나무뿌리유래사포닌분획물을함유하는조성물에관한것으로서, 보다상세하게는차나무뿌리추출물을효소로처리한다음분리한사포닌분획물을사용함으로써기존차나무뿌리에서추출한사포닌분획물에비하여세포독성을저감시켜피부에대한안전성을높이고, 이와같이얻은사포닌분획물을조성물에더 높은수준으로포함시킬수 있어더 우수한피부상태개선효과를제공할수 있는조성물에관한것이다.
摘要翻译：本发明涉及含有来自酶处理的茶树根的皂角苷成分的组合物。更具体地说，本发明涉及能够提供皮肤改善皮肤状况的优异效果的组合物。为此，使用酶处理茶树根提取物后分离出的皂角苷成分，与从茶树根中提取的现有皂苷成分相比，具有更好的降低细胞毒性的作用。因此，皮肤的安全性增加，因此可以在组合物中加入更多的皂角苷含量。

8. 发明公开

KR1020140115140A 디소듐 R-당-설포석시네이트를 함유한 두피 및/또는 모발용 조성물 审中-实审
标题翻译：含硫磺酸钠的鳞屑和头发的组合物
公开(公告)号：KR1020140115140A
公开(公告)日：2014-09-30
申请号：KR1020130029861
申请日：2013-03-20
申请人： (주)아모레퍼시픽
发明人： 정윤혁 , 강병하 , 조선아 , 이존환
IPC分类号： A61K8/60 , A61K8/46 , A61K8/73 , A61Q19/00
摘要： The present invention relates to a composition for scalp or hair, and more specifically, to a composition for scalp or hair, which uses disodium R-glucose-sulfosuccinate as a surfactant and stabilizes sensitive, irritant, or reactive scalps, thereby making the scalp healthy, giving strength to hair, and enhancing the hair roots.
摘要翻译：本发明涉及一种头皮或毛发用组合物，更具体地，涉及使用R-葡萄糖 - 磺基琥珀酸二钠作为表面活性剂的头皮或毛发用组合物，稳定敏感，刺激性或反应性的头皮，从而使头皮健康赋予头发力量，增强发根。

9. 发明授权

KR100964428B1 약용식물 추출물을 포함하는 피부 염증 완화용 화장료조성물 有权
标题翻译：含有天然药用植物提取物以减轻皮肤炎症的化妆品组合物
公开(公告)号：KR100964428B1
公开(公告)日：2010-06-16
申请号：KR1020080011719
申请日：2008-02-05
申请人： (주)아모레퍼시픽 , 인제대학교 산학협력단
发明人： 이찬우 , 김한성 , 조선아 , 강찬구 , 김진웅 , 김한곤 , 김은경 , 구경아 , 윤현주 , 이범종
IPC分类号： A61K8/97 , A61Q19/00
摘要： 본 발명은 스트렙토컬론 주벤타스(
Streptocaulon

juventas ) 외 12종의 약용 식물 추출물을 함유함으로써 산화 질소(NO) 매개 염증 및 레티노이드에 의한 피부자극 및 염증을 완화시키는 효과를 가지는 화장료 조성물을 제공한다. 상기 화장료 조성물은 산화질소(NO) 매개 염증과 관련된 피부 질환을 예방할 수 있고, 레티노이드 자극 및 염증으로부터 피부를 보호하고, 염증성 매개분자의 발현을 조절하여 레티노이드에 의한 피부 자극을 완화할 수 있다.
아시아 자생 약용 식물, 레티노이드, 산화 질소, 자극완화, 염증

10. 发明公开

KR1020080051201A 스핑고실포스포릴콜린 또는 그의 유도체를 활성성분으로포함하는 건선 치료용 약학 조성물 无效
标题翻译：用于处理其中包含苯并恶唑啉酮或其衍生物的PSORIASIS的药物组合物
公开(公告)号：KR1020080051201A
公开(公告)日：2008-06-11
申请号：KR1020060121861
申请日：2006-12-05
申请人： (주)아모레퍼시픽
发明人： 김형준 , 김혁 , 성기사 , 김대권 , 조선아 , 김광미 , 노민수 , 이창훈 , 김정주
IPC分类号： A61K31/685 , A61K31/661
CPC分类号： A61K31/688 , Y10S514/863 , Y10S514/886
摘要： A pharmaceutical composition comprising sphingosylphosphorylcholine or derivatives thereof is provided to inhibit proliferation and promote differentiation of keratinocyte, inhibit proliferation of splenocyte and T cell, induce reduction of leucocyte, and reduce mouse ear swelling induced by TPA(tetradecanoyl phorbol acetate), so that the composition is useful for treating psoriasis. A pharmaceutical composition for treating psoriasis comprises sphingosylphosphorylcholine(SPC) represented by the formula(1) or derivatives thereof and is formulated as tablet, pill, powder, sachet, elixir, suspension, emulsion, solution, syrup, aerosol, soft or hard gelatin capsule, sterile injection or sterile powder, wherein the daily dosage is 1-100 mg/kg, preferably 5-70 mg/kg.
摘要翻译：提供包含鞘氨醇磷酰胆碱或其衍生物的药物组合物，以抑制角质形成细胞的增殖和促进分化，抑制脾细胞和T细胞的增殖，诱导白细胞的减少，并减少TPA（十四酰基佛波醇乙酸酯）诱导的小鼠耳肿胀，使组合物可用于治疗牛皮癣。用于治疗牛皮癣的药物组合物包含由式（1）表示的鞘糖基磷酰胆碱（SPC）或其衍生物，并配制成片剂，丸剂，粉末，小药囊，酏剂，悬浮液，乳剂，溶液，糖浆，气雾剂，软或硬明胶胶囊无菌注射或无菌粉末，其中日剂量为1-100mg / kg，优选5-70mg / kg。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式