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    • 3. 发明公开
    • 펜에틸 벤조에이트 유도체 및 그의 제조방법
    • 苯乙烯衍生物及其制备方法
    • KR1020080036734A
    • 2008-04-29
    • KR1020060103352
    • 2006-10-24
    • 인제대학교 산학협력단
    • 이범종손은미구경아이찬우김한성
    • C07C63/08C07C69/773C07C69/78
    • A phenethyl benzoate derivative, and a method for preparing the phenethyl benzoate derivative are provided to obtain a novel phenethyl benzoate derivative having a hydroxyl group at the 2 and/or 3-positions. A phenethyl benzoate derivative is represented by the formula 1, wherein R1 to R14 are identical or different one another and are H, a halogen atom, a carboxyl group, an amino group, a nitro group, a cyano group, a substituted or unsubstituted C1-C20 alkyl group, a substituted or unsubstituted C1-C20 alkoxy group, a substituted or unsubstituted C2-C20 alkenyl group, a substituted or unsubstituted C2-C20 alkynyl group, a substituted or unsubstituted C1-C20 heteroalkyl group, a substituted or unsubstituted C6-C30 aryl group, a substituted or unsubstituted C7-C30 arylalkyl group, a substituted or unsubstituted C5-C30 heteroaryl group, or a substituted or unsubstituted C3-C30 heteroarylalkyl group, and at least of them can be combined to form a five, six or seven-membered ring, but at least one of R6, R7, R9 and R10 is a hydroxyl group.
    • 提供苯甲酸苯乙酯衍生物,以及制备苯甲酸苯乙酯衍生物的方法,以获得在2和/或3-位具有羟基的新型苯乙酸苯乙酯衍生物。 苯甲酸苯乙酯衍生物由式1表示,其中R 1至R 14彼此相同或不同,为H,卤素原子,羧基,氨基,硝基,氰基,取代或未取代的C1 -C 20烷基,取代或未取代的C 1 -C 20烷氧基,取代或未取代的C 2 -C 20烯基,取代或未取代的C 2 -C 20炔基,取代或未取代的C 1 -C 20杂烷基,取代或未取代的C 6 -C 30芳基,取代或未取代的C 7 -C 30芳烷基,取代或未取代的C 5 -C 30杂芳基或取代或未取代的C 3 -C 30杂芳基烷基,并且至少它们可以组合形成五 或七元环,但R 6,R 7,R 9和R 10中的至少一个为羟基。
    • 8. 发明授权
    • 판두라틴 유도체를 함유하는 피부 미백용 화장료 조성물
    • 白皮质组合物外用于含有潘多林衍生物的皮肤
    • KR100829819B1
    • 2008-05-16
    • KR1020070054863
    • 2007-06-05
    • (주)아모레퍼시픽황재관
    • 이찬우김한성김덕희장이섭윤지훈심재석황재관
    • A61K8/35A61K8/34A61Q19/02
    • A skin whitening cosmetic composition comprising a panduratin derivative or an extract of Kaempferia Pandurata is provided to be safely used to skin without side effects and show excellent pigmentation inhibitory effect by inhibiting melanogenesis, thereby improving liver spots or freckles and showing excellent skin whitening effect. A skin whitening cosmetic composition comprises 0.001-10 wt.% of at least one panduratin derivative selected from the group consisting of compounds represented by formulae(1) to (3), wherein the panduratin derivative is extracted from Kaempferia Pandurata. Further, the skin whitening cosmetic composition is cosmetic water, cream, massage cream, essence, eye cream, eye essence, cleansing cream, cleansing form, cleansing water, pack, gel, powder, body lotion, body cream, body oil and body essence.
    • 提供一种皮肤美白化妆品组合物,其包含潘多汀衍生物或山茶皮提取物以安全地用于皮肤而没有副作用,并通过抑制黑素生成显示出优异的色素沉着抑制作用,从而改善肝斑或雀斑并显示出优异的皮肤美白效果。 皮肤美白化妆品组合物包含0.001-10重量%的至少一种选自由式(1)至(3)表示的化合物的潘多肽衍生物,其中所述潘多汀衍生物从山茶中提取。 此外,皮肤美白化妆品组合物是化妆水,奶油,按摩霜,精华,眼霜,眼睛精华,清洁霜,清洁剂,清洁水,包装,凝胶,粉末,身体乳液,身体霜,身体油和身体精华 。
    • 10. 发明公开
    • 적송엽 추출물을 함유하는 피부노화 방지용 피부 외용제조성물
    • 用于包含红松针的外用皮肤应用的抗菌组合物
    • KR1020070082635A
    • 2007-08-22
    • KR1020060015467
    • 2006-02-17
    • (주)아모레퍼시픽
    • 주희경이성일이종찬김연준김한성
    • A61K8/97A61Q19/08
    • An anti-aging composition for external skin application containing the extract of red pine needles is provided to remove free radicals, protect cell membrane damage due to UV(ultraviolet), inhibit production of reactive oxygen species due to UV, restore expression decrease of superoxide dismutase and catalase due to UV, promote production of HSP70(heat shock protein 70) and suppress MMP-2(matrix metal protease-2) biosynthesis. The anti-aging composition for external skin application contains 0.001-10.0 wt.% of the extract of red pine needles which is prepared by extracting freeze-dried red pine needles with 70% ethanol at room temperature for 48 hours, and evaporating ethanol from the extract by using an evaporator, and has a formulation selected from solution, gel, emulsion, suspension, microemulsion, microcapsule, microgranule, dispersion, cream, skin, lotion, powder, ointment, spray or stick.
    • 提供含有红松提取物的外用皮肤抗衰老组合物,以除去自由基,保护由紫外线(紫外线)引起的细胞膜损伤,抑制紫外线引起的活性氧的产生,恢复超氧化物歧化酶的表达降低 和由于UV引起的过氧化氢酶,促进HSP70(热休克蛋白70)的产生并抑制MMP-2(基质金属蛋白酶-2)生物合成。 用于外用皮肤的抗衰老组合物含有0.001-10.0重量%的红松针提取物,其通过在室温下用70%乙醇提取冷冻干燥的红松针48小时而制备,并将乙醇从 通过使用蒸发器提取,并且具有选自溶液,凝胶,乳液,悬浮液,微乳液,微胶囊,微粒,分散体,霜剂,皮肤,洗剂,粉末,软膏,喷雾或棒状物的制剂。