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    • 1. 发明公开
    • 불포화 지방산 및 층상형 금속 수산화물의 혼성체, 그 제조방법, 및 그 혼성체를 포함하는 기능성 식품 및 피부외용제
    • 具有层状金属氢氧化物的不饱和脂肪酸的混合物,其制备方法和功能性食品以及包含其的外部制剂
    • KR1020090055948A
    • 2009-06-03
    • KR1020070122843
    • 2007-11-29
    • (주)씨앤팜
    • 강문식이윤주최진호김동윤
    • C07F19/00C07F3/02C07F5/06C07F3/00
    • A61K8/27A61K8/37A61K31/215A61K33/30
    • A hybrid with layered metal hydroxide is provided to increase the stability of unsaturated fatty acid, easily formulate, and efficiently apply the unsaturated fatty acid into the skin. A hybrid of an undsaturated fatty acid and layered metal hydroxide is obtained by introduction of unsaturated fatty acid between the layers of layered metal hydroxide and hybridization. The metal double layer hydroxide is a compound of the chemical formula 1([M(II)1-xM(III)x(OH)2]X+(An-)X/n.yH2O) or formula 2([M(II)(OH)x'](A)(2-x')/n.yH2O). The hybrid is reformed with tocopherol, lauric acid, tetra-ethyl orthosilicate (TEOS), glyceryl monostearate (GMS) or dimethicone. The method for manufacturing the hybrid comprises: a step of producing essential fatty acid and bivalent metal salt solution; and a step of adding base to adjust to pH 4-8 and collecting the precipitate.
    • 提供了层状金属氢氧化物的混合物,以增加不饱和脂肪酸的稳定性,容易配制,并有效地将不饱和脂肪酸施用于皮肤。 通过在层状金属氢氧化物层之间引入不饱和脂肪酸和杂交获得不饱和脂肪酸和层状金属氢氧化物的杂化物。 金属双层氢氧化物是化学式1([M(II)1-xM(III)x(OH)2] X +(An-)X / n.yH 2 O)或式2([M(II )(OH)X '](A)(2-X')/ n.yH2O)。 用生育酚,月桂酸,原硅酸四乙酯(TEOS),单硬脂酸甘油酯(GMS)或聚二甲基硅氧烷改性混合物。 制造杂化物的方法包括:生产必需脂肪酸和二价金属盐溶液的步骤; 以及添加碱以调节至pH 4-8并收集沉淀物的步骤。