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11. 发明授权

KR101094306B1 타이모퀴논류 화합물을 함유하는 피부 미백용 조성물 有权
标题翻译：包含具有皮肤白化活性的三茂铁化合物的组合物
公开(公告)号：KR101094306B1
公开(公告)日：2011-12-19
申请号：KR1020110052442
申请日：2011-05-31
申请人： 에스케이바이오랜드 주식회사
发明人： 김기호 , 김영희 , 고강일 , 김진국 , 허우범 , 박선희 , 이수연
IPC分类号： A61K8/35 , A61Q19/02 , A61Q19/00
摘要： PURPOSE: A pharmaceutical composition containing thymoquinone compounds for treating skin pigmentary disorders and to suppress tyrosinase activity and melanogenesis. CONSTITUTION: A cosmetic composition for skin whitening contains 0.0001-50 wt% of thymoquinone compounds of structural formula 1, 2, or 3 as an active ingredient. The composition is manufactured in the form of a skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, massage cream, foundation, hand cream, pack, soap, cleansing foam, or body cleanser. A pharmaceutical composition for treating and preventing skin pigmentary disorder contains the thymoquinone compounds as an active ingredient. The pharmaceutical composition is manufactured in the form of a cream, patch, spray, ointment, liniment, paste, or cataplasma.
摘要翻译：目的：含有用于治疗皮肤色素障碍并抑制酪氨酸酶活性和黑素生成的胸腺醌化合物的药物组合物。构成：皮肤美白用化妆品组合物含有0.0001-50重量％的结构式1,2或3的胸腺醌化合物作为活性成分。该组合物以皮肤洗剂，皮肤柔肤剂，皮肤调色剂，收敛剂，洗剂，乳液，按摩霜，粉底，护手霜，包装，肥皂，清洁泡沫或身体清洁剂的形式制成。用于治疗和预防皮肤色素障碍的药物组合物含有作为活性成分的胸腺醌化合物。药物组合物以奶油，贴剂，喷雾剂，软膏剂，搽剂，糊剂或粘膜剂的形式制备。

12. 发明公开

KR1020100124033A 멜라닌 생성을 억제하는 닭의장풀 추출물을 함유하는 미백 화장료 조성물 无效
标题翻译：化妆品组合物包含提取物的芬兰丙烯酸酯具有维生素A合成的抑制活性
公开(公告)号：KR1020100124033A
公开(公告)日：2010-11-26
申请号：KR1020090043068
申请日：2009-05-18
申请人： 에스케이바이오랜드 주식회사
发明人： 김기호 , 김영희 , 한창성 , 박선희 , 이방용 , 이승현 , 이강혁
IPC分类号： A61K8/97 , A61Q19/02
CPC分类号： A61K8/97 , A61K36/185 , A61K2236/33 , A61Q19/02 , Y10S514/844
摘要： PURPOSE: A cosmetic composition containing Commelina communis L. extract for skin whitening is provided to suppress tyrosinase and melanogenesis. CONSTITUTION: A cosmetic composition for whitening contains Commelina communis L. extract as an active ingredient. The Commelina communis L. extract is isolated using water, organic solvent or mixture solvent thereof. The organic solvent is alcohol of 1-4 carbon atoms, propylene glycol, butylenes glycol or glycerin. The composition is used in the form of skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutrition lotion, massage cream, and pack.
摘要翻译：目的：提供含有猕猴桃提取物用于皮肤美白的化妆品组合物，以抑制酪氨酸酶和黑素生成。构成：美白化妆品组合物含有枸杞提取物作为活性成分。使用水，有机溶剂或其混合溶剂分离Comm藜提取物。有机溶剂是1-4个碳原子的醇，丙二醇，丁二醇或甘油。该组合物以皮肤洗剂，皮肤柔肤剂，皮肤调色剂，收敛剂，洗剂，乳液，湿润剂，营养乳液，按摩膏和包装的形式使用。

13. 发明公开

KR1020100083232A 에쿠올을 함유하는 피부주름개선용 화장료 조성물 无效
标题翻译：化妆品组合物，用于皮肤皱纹改善包含均质
公开(公告)号：KR1020100083232A
公开(公告)日：2010-07-22
申请号：KR1020090002518
申请日：2009-01-13
申请人： 에스케이바이오랜드 주식회사
发明人： 김기호 , 김영희 , 박선희 , 김현미 , 고강일 , 박수진 , 한창성
IPC分类号： A61K8/49 , A61Q19/08
CPC分类号： A61K8/498 , A61K2800/782 , A61Q19/08
摘要： PURPOSE: A cosmetic composition for anti-aging and anti-wrinkle containing equol is provided to suppress elastase and MMP-1(matrix metalloproteinase-1) expression. CONSTITUTION: A cosmetic composition for anti-wrinkle contains equol as an active ingredient. The equol is chemically synthesized from diadzein and is contained in 0.01-5.0 weight% based on total weight. The cosmetic composition is used in the form of skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, and nutrition lotion.
摘要翻译：目的：提供含有雌马酚的抗衰老抗皱化妆品组合物，以抑制弹性蛋白酶和MMP-1（基质金属蛋白酶-1）的表达。构成：抗皱用化妆品组合物含有雌马酚作为活性成分。雌马酚是由二十一碳烷化学合成的，其含量为0.01-5.0重量％，基于总重量。化妆品组合物以皮肤洗剂，皮肤柔软剂，皮肤调色剂，收敛剂，洗剂，乳液，湿润剂和营养洗剂的形式使用。

14. 发明公开

KR1020100058331A 호장근 추출물 또는 이로부터 분리된 레스베라트롤을 함유하는 자외선 차단용 조성물 无效
标题翻译：包含FALLOPIA JAPONICA萃取物或RESVERATROL化合物的降解组合物分离
公开(公告)号：KR1020100058331A
公开(公告)日：2010-06-03
申请号：KR1020080117091
申请日：2008-11-24
申请人： (주)아모레퍼시픽 , 에스케이바이오랜드 주식회사
发明人： 박창훈 , 박정은 , 김지은 , 김기호 , 김영희
IPC分类号： A61K8/97 , A61Q17/04
摘要： PURPOSE: A composition isolated from natural extract or compound isolated from the same is provided to ensure strong UV protection and stability without skin irritation. CONSTITUTION: A cosmetic composition for UV protection contains Fallopia japonica extract or resveratrol isolated from the same as an active ingredient. An external use composition for UV protection contains Fallopia japonica extract or resveratrol as an active ingredient. The Fallopia japonica extract is isolated from stem, leaf, seed, and root of Fallopia japonica by macerating, room temperature extraction, hot water extraction, or fermentation extraction.
摘要翻译：目的：提供从天然提取物或从其分离的化合物分离的组合物，以确保强力的紫外线防护和稳定性，不会引起皮肤刺激。构成：用于紫外线防护的化妆品组合物含有与活性成分相同的罂粟萃取物或白藜芦醇。用于紫外线防护的外用组合物含有茯苓提取物或白藜芦醇作为活性成分。通过浸泡，室温提取，热水提取或发酵提取，分离of粳提取物从枸杞的茎，叶，种子和根中分离。

15. 发明授权

KR100947638B1 용암해수염을 함유하는 조성물 有权
标题翻译：包含熔岩海水盐的组合物
公开(公告)号：KR100947638B1
公开(公告)日：2010-03-15
申请号：KR1020060125363
申请日：2006-12-11
申请人： 에스케이바이오랜드 주식회사
发明人： 김기호 , 김영희 , 김진국 , 김경태 , 양홍철 , 이수희 , 김지연
IPC分类号： A61K8/19 , A61K8/97 , A61Q19/00
摘要： 본 발명은 용암해수염 및 녹차, 홍차, 알로에, 포도, 바나나 및 사과 추출물로부터 선택된 하나 이상을 함유하는 용암해수염을 유효성분으로 함유하는 조성물에 관한 것으로, 본 발명의 조성물은 피부의 보습력 증진, 탄력 증진 및 항염증 효과를 갖는 피부 보호 및 개선용 화장료, 입욕제, 비누조성물 및 충치 예방 효과를 갖는 구강용 조성물로 유용하게 이용할 수 있다.
용암해수염, 보습력 증진, 탄력 증진, 항염증, 화장료, 입욕제, 비누조성물, 구강조성물

16. 发明公开

KR1020090093613A 용암해수 미네랄수를 함유하는 육모제 조성물 有权
标题翻译：用于促进包含马卡海水的头发生长的组合物
公开(公告)号：KR1020090093613A
公开(公告)日：2009-09-02
申请号：KR1020080019236
申请日：2008-02-29
申请人： 에스케이바이오랜드 주식회사
发明人： 김기호 , 김영희 , 김경태 , 한창성 , 양홍철 , 박수진 , 박덕배 , 강희경
IPC分类号： A61K8/19 , A61K8/33 , A61Q7/00
CPC分类号： A61K8/965 , A61K8/02 , A61K8/19 , A61K8/97 , A61K2800/782 , A61K2800/83 , A61Q5/00 , A61Q7/00
摘要： A natural plant extract which is isolated with mineral water is provided to ensure the suppression effect of 5alpha-reductase activation and use as additive. A composition for promoting hair growth or preventing and treating hair loss comprises 0.01~10 weight% mineral water of magma seawater as an active ingredient. The mineral water of magma seawater comprises 1~100 ppb of vanadium and 1~100 ppb of germanium. The mineral water of magma seawater is obtained by desalinating the magma seawater which is from underground 100~200 m in Jeju island. A composition for promoting hair growth is used in the form of shampoo, rinse, hair tonic, cosmetic product for hair care and spray.
摘要翻译：提供用矿泉水分离的天然植物提取物，以确保5α-还原酶活化的抑制作用和用作添加剂。用于促进毛发生长或预防和治疗脱发的组合物包含0.01〜10重量％的岩浆海水矿物水作为活性成分。岩浆海水矿泉水含有1〜100ppb的钒和1〜100ppb的锗。岩浆海水的矿泉水是通过在济州岛从地下100〜200米的海水脱盐而得到的。用于促进头发生长的组合物以洗发剂，漂洗剂，滋补剂，用于护发和喷雾的化妆品的形式使用。

17. 发明公开

KR1020090092949A 곰의말채 추출물을 함유하는 피부노화방지 또는 미백용화장료 조성물 无效
标题翻译：化妆品组合物，用于预防皮肤老化或白化皮肤，包括来自金丝桃的提取物
公开(公告)号：KR1020090092949A
公开(公告)日：2009-09-02
申请号：KR1020080018217
申请日：2008-02-28
申请人： 에스케이바이오랜드 주식회사
发明人： 김기호 , 김영희 , 김기수 , 한창성 , 양홍철 , 최현진 , 고지현 , 이강혁
IPC分类号： A61K8/97 , A61Q19/02 , A61Q19/08 , A61Q19/00
CPC分类号： A61K8/97 , A61K36/40 , A61Q19/02 , A61Q19/08 , Y10S514/844
摘要： A cosmetic composition for skin whitening or anti-aging, which contains a Cornus macrophylla extract is provided to maintain skin elasticity and suppress wrinkle and melanogenesis through the suppression of elastase activity and collagenase activity. A cosmetic composition for anti-aging or skin whitening contains 0.01-10 weight% of Cornus macrophylla extract. The Cornus macrophylla extract is isolated using water, organic solvent, or their mixture. The organic solvent is ethanol, methanol, propyleneglycol, butyleneglycol, glyserine, hydrous ethanol, hydrous butyleneglycol, hydrous propyleneglycol, hexane or ethylacetate. The composition is used in the form of skin lotion, skin softener, skin toner, hand cream, essence, pack, soap, cleansing foam, foundation, loose powder and eye shadow.
摘要翻译：提供含有栀子提取物的用于皮肤美白或抗衰老的化妆品组合物，以通过抑制弹性蛋白酶活性和胶原酶活性来保持皮肤弹性并抑制皱纹和黑素生成。用于抗衰老或皮肤美白的化妆品组合物含有0.01-10重量％的萸草提取物。使用水，有机溶剂或其混合物分离栀子提取物。有机溶剂为乙醇，甲醇，丙二醇，丁二醇，甘氨酸，含水乙醇，含水丁二醇，含水丙二醇，己烷或乙酸乙酯。该组合物以皮肤洗剂，皮肤柔肤剂，皮肤调色剂，护手霜，精华，包装，肥皂，清洁泡沫，粉底，松散粉末和眼影的形式使用。

18. 发明授权

KR100845970B1 항노화 활성을 갖는 노르베르게닌을 함유하는 피부외용조성물 有权
标题翻译：一种局部用组合物，其含有表现出抗衰老活性的诺贝恩根素
公开(公告)号：KR100845970B1
公开(公告)日：2008-07-11
申请号：KR1020060041236
申请日：2006-05-08
申请人： 에스케이바이오랜드 주식회사
发明人： 김기호 , 김영희 , 고강일 , 최봉락 , 김경태 , 이수희
IPC分类号： A61K31/352 , A61K31/35 , A61P39/06
摘要： 본 발명은 항노화 효과가 뛰어난 노르베르게닌을 함유하는 피부외용 약학조성물 또는 화장료 조성물에 관한 것으로, 콜라게네이즈 발현억제 효과 및 콜라겐 합성 촉진효과를 나타냄으로서 항노화 활성을 갖는 노르베르게닌을 포함하는 피부외용 약학조성물 또는 화장료 조성물에 관한 것이다.
노르베르게닌, 항노화, 피부외용, 약학조성물, 화장료 조성물

19. 发明公开

KR1020080022739A 자기유화 전달체 및 이의 제조방법 有权
标题翻译：一种自我发射载体及其制备方法
公开(公告)号：KR1020080022739A
公开(公告)日：2008-03-12
申请号：KR1020060086292
申请日：2006-09-07
申请人： 에스케이바이오랜드 주식회사
发明人： 이승현 , 김영희 , 조남석 , 김태현 , 유희종 , 김기호
IPC分类号： A61K9/127 , A61K8/14 , B82Y5/00
CPC分类号： A61K8/14 , A61K8/355 , A61K8/97 , A61K2800/413 , B82Y5/00
摘要： A self-emulsifying carrier is provided to form nanoparticles voluntarily during the dissolving process, increase the content of lipophilic components, and maintain stability of the active components for a long time, so that it is applied to various applications including cosmetics, medicines and health food. A method for preparing the self-emulsifying carriers comprises the steps of: dissolving lipophilic components in nonpolar oil; adding lecithin and surfactant to polyol or multivalent alcohol and dispersing them uniformly; slowly adding the active components prepared to the dispersed lecithin to form pre-emulsion; and passing the pre-emulsion through a microfluidizer to form the self-emulsifying carriers, wherein the lipophilic component is astaxanthin, beta-carotene, lycopene, lutein, kaempferol, coenzyme Q10, polyphenol, vitamin E and its derivative, vitamin A and its derivative, provitamin D2 and its derivative, gensenoside, linoleic acid, gamma-linoleic acid, docosahexaenoic acid(DHA), eicosapentaenoic acid(EPA), grape seed oil, resveratrol, beta-sitosterol, genistein, oil soluble licorice extract or its mixture. Further, a content rate of the lipophilic components : the nonpolar oil : the lecithin : the polyol : the surfactant is 0.1~20 : 0.2~20 : 0.2~5 : 30~97 : 0.05~2.0.
摘要翻译：提供自乳化载体以在溶解过程中自主形成纳米颗粒，增加亲油性成分的含量，长时间保持活性成分的稳定性，使其适用于各种用途，包括化妆品，药品和保健食品。制备自乳化载体的方法包括以下步骤：将亲油组分溶解在非极性油中; 将卵磷脂和表面活性剂加入到多元醇或多元醇中并均匀分散; 将制备的活性成分缓慢加入到分散的卵磷脂中以形成预乳液; 并将预乳液通过微流化器以形成自乳化载体，其中亲脂性组分是虾青素，β-胡萝卜素，番茄红素，叶黄素，山奈酚，辅酶Q10，多酚，维生素E及其衍生物，维生素A及其衍生物（DHA），二十碳五烯酸（EPA），葡萄籽油，白藜芦醇，β-谷甾醇，染料木黄酮，油溶性甘草提取物或其混合物，其中，维生素D2及其衍生物，生物素，亚油酸，γ-亚油酸，二十二碳六烯酸（DHA）此外，亲油成分的含量比例：非极性油：卵磷脂：多元醇：表面活性剂为0.1〜20：0.2〜20：0.2〜5：30〜97：0.05〜2.0。

20. 发明授权

KR100771829B1 유해 환경에서 유래되는 스트레스로부터 피부를 보호하는효능을 갖는 식물 혼합추출물을 함유하는 조성물 有权
标题翻译：包含植物提取物的组合物，用于保护由于有害环境而引起的紧张的皮肤
公开(公告)号：KR100771829B1
公开(公告)日：2007-10-30
申请号：KR1020060055001
申请日：2006-06-19
申请人： 보령메디앙스 주식회사 , 에스케이바이오랜드 주식회사
发明人： 설장호 , 백남용 , 김동호 , 고재건 , 김동현 , 이호준 , 김학철 , 이복구 , 김기호 , 김영희 , 고강일 , 한창성
IPC分类号： A61K8/97 , A61Q19/00
摘要： A cosmetic composition comprising a plant mixture extract is provided to alleviate skin damage caused by stress of the outside environment and show skin protecting effect by inhibiting over-reaction and erythema and maintaining skin moisture, thereby being useful as a skin protecting cosmetic composition. A cosmetic composition having skin protecting effect from active oxygen, skin dryness and allergy comprises a plant mixture extract consisting of 10-15% of green tea, 5-10% of Pinus sylvestris, 5-10% of Glycyrrhiza uralensis, 5-10% of Paeonia suffruticosa Andrews, 8-12% of Scutellaria baicalensis George, 5-10% of Sophora flavescens, 1-5% of Glycine max, 1-5% of aloe, 1-5% of Mori Cotex Radicis, 5-10% of persimmon leaves, 1-5% of kiwi, 5-10% of Polygoni Multiflori Radix, 5-10% of camellia and 10-15% of Panax ginseng, wherein the extract is prepared by extracting the mixture using water, ethanol, methanol, propanol, butanol, acetone, ethylacetate, hexane, benzene, chloroform, glycerine, butylene glycol or propylene glycol at a temperature of 10-37 deg.C for 1 to 15 days and the content of the dried extract is 0.01-10.0 weight/volume %.
摘要翻译：提供了包含植物混合物提取物的化妆品组合物以减轻由外部环境的压力引起的皮肤损伤，并通过抑制过度反应和红斑并保持皮肤水分显示皮肤保护作用，从而可用作皮肤保护性化妆品组合物。具有活性氧，皮肤干燥和过敏的皮肤保护作用的化妆品组合物包括由10-15％的绿茶，5-10％的樟子松，5-10％的甘草，5-10％芍药芍药，黄芩8-12％，苦参5-10％，甘氨酸1-5％，芦荟1-5％，山楂1〜5％的柿子，1-5％的猕猴桃，5-10％的黄芪，5-10％的山茶和10-15％的人参，其中所述提取物是通过使用水，乙醇，甲醇提取混合物制备的丙醇，丁醇，丙酮，乙酸乙酯，己烷，苯，氯仿，甘油，丁二醇或丙二醇，温度为10-37℃，持续1〜15天，干燥提取物的含量为0.01-10.0重量/ 体积％。

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