基本信息:
- 专利标题： Method for producing phosphatide salt
- 专利标题（中）：生产磷酸盐的方法
- 申请号：JP2010173300 申请日：2010-08-02
- 公开(公告)号：JP2011160795A 公开(公告)日：2011-08-25
- 发明人： RUTENBERG DAVID
- 申请人： Lipogen Ltd , リポゲン エルティディ.
- 专利权人： Lipogen Ltd,リポゲン エルティディ.
- 当前专利权人： Lipogen Ltd,リポゲン エルティディ．
- 优先权： US70007310 2010-02-04
- 主分类号： C12P9/00
- IPC分类号： C12P9/00
摘要：
PROBLEM TO BE SOLVED: To provide a novel method for producing a phosphatide-salt complex.
SOLUTION: The method for producing the phosphatide-salt complex includes steps of: using at least one raw material lecithin as a substrate; and enzymatically processing at least one raw material lecithin with phospholipase-D (PLD), racemic body or enantiomerically pure serine, or amine in an aqueous carboxylate complex solution, wherein the step of processing is performed in a single-phase reaction environment to produce the phosphatide-salt complex having a structural fatty-acid chain derived from at least one raw material lecithin. The step of processing is performed at a pH in the range of about 4.5-8.0 at a temperature in the range of about 25-60°C. The aqueous carboxylate-salt complex solution is formed from an aqueous solution of a carboxylic acid with a chain length of C2-C8 and a salt in an approximately 1:2 (weight per weight) acid-to-salt ratio.
COPYRIGHT: (C)2011,JPO&INPIT
摘要（中）：
SOLUTION: The method for producing the phosphatide-salt complex includes steps of: using at least one raw material lecithin as a substrate; and enzymatically processing at least one raw material lecithin with phospholipase-D (PLD), racemic body or enantiomerically pure serine, or amine in an aqueous carboxylate complex solution, wherein the step of processing is performed in a single-phase reaction environment to produce the phosphatide-salt complex having a structural fatty-acid chain derived from at least one raw material lecithin. The step of processing is performed at a pH in the range of about 4.5-8.0 at a temperature in the range of about 25-60°C. The aqueous carboxylate-salt complex solution is formed from an aqueous solution of a carboxylic acid with a chain length of C2-C8 and a salt in an approximately 1:2 (weight per weight) acid-to-salt ratio.
COPYRIGHT: (C)2011,JPO&INPIT
待解决的问题：提供一种生产磷脂 - 盐复合物的新方法。 解决方案：制备磷脂 - 盐复合物的方法包括以下步骤：使用至少一种原料卵磷脂作为底物; 并在羧酸盐复合物水溶液中用磷脂酶-D（PLD），外消旋体或对映异构体纯的丝氨酸或胺酶处理至少一种原料卵磷脂，其中处理步骤在单相反应环境中进行以产生 具有衍生自至少一种原料卵磷脂的结构脂肪酸链的磷脂 - 盐配合物。 在大约25-60℃的温度下，在约4.5-8.0的pH范围内进行处理步骤。 羧酸盐水溶液配合物溶液由链长为C 2 -C 8的羧酸水溶液和约1：2（重量/重量/重量）酸 - 盐比的盐形成。 版权所有（C）2011，JPO＆INPIT