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    • 1. 发明专利
    • Composite transfusion
    • 复合材料传输
    • JPS6178719A
    • 1986-04-22
    • JP20106684
    • 1984-09-25
    • Tanabe Seiyaku Co LtdTerumo Corp
    • SAMEJIMA MASAYOSHIMATSUDA SABUROWAKABAYASHI TOSHIOHAYAKAWA NAOKI
    • A61K9/08A23L1/304A23L1/305A61K31/195A61K31/40A61K31/405A61K31/415A61K31/70A61K33/00A61K38/00A61K38/01
    • A61K33/00A23L33/16A23L33/175A61K38/01A61K31/7004A61K2300/00
    • PURPOSE: To provide a composite transfusion containing a reducing sugar, physiological amino acid and electrolyte at specific balanced ratio, excellent from nutritional viewpoint, and capable of suppressing the browning phenomenon.
      CONSTITUTION: The objective composite transfusion essentially resistant to discoloration can be prepared by using a reducing sugar (e.g. glucose, maltose, etc.), physiological amino acids, and electrolytes of the table I at ratios and amounts shown in the table. The concentration product of the reducing sugar and amino acid is preferably 7W25, especially 12W24 to improve the stability of the transfusion. The pH of the transfusion is preferably 4.0W6.0. It can be prepared according to the method used in the preparation of transfusion or injections, and may be sterilized by heating. Since the transfusion can be used as it is without combining with other agent, various problems caused by the combined use, e.g. variation of pH, contamination with microorganisms and foreign materials, etc., can be avoided.
      COPYRIGHT: (C)1986,JPO&Japio
    • 目的:提供以均衡比例含有还原糖,生理氨基酸和电解质的复合输液,营养观点优良,能抑制褐变现象。 构成:可以通过使用表I所示比例和量的表I的还原糖(例如葡萄糖,麦芽糖等),生理氨基酸和电解质来制备基本上抗变色的目的复合输液。 还原糖和氨基酸的浓度乘积优选为7-25,特别是12-24,以提高输血的稳定性。 输血的pH优选为4.0-6.0。 可以根据输血或注射制剂中使用的方法制备,可以通过加热灭菌。 由于输液可以原样使用而不与其他药剂组合使用,所以由组合使用引起的各种问题,例如, 可以避免pH的变化,微生物和异物的污染等。