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1. 发明专利

JPH1146789A PRODUCTION OF UDP-GALNAC 失效
公开(公告)号：JPH1146789A
公开(公告)日：1999-02-23
申请号：JP21490197
申请日：1997-08-08
申请人： TOMITA PHARMA
发明人： KABAYAMA MINEAKI , SAKIYAMA TORU
IPC分类号： C12P19/30 , C07H1/06 , C07H19/10
摘要： PROBLEM TO BE SOLVED: To obtain the subject compound useful for the development of medicines, etc. at a low cost on a large seale by allowing an epimerase to act on VDP-GlcNac and subsequently applying a column to the product to separate the compound from the raw material, wherein a lectin capable of selectively binding to the compound is immobilized on the column. SOLUTION: This method for producing VDP-GalNAc comprises allowing an epimerase to act on VDP-GlcNAc to convert into the VDP-GalNAc, subjecting the reaction mixture to a column to separate the VDP-GalNAc from the VDP-GlcNAc. A lectin capable of selectively binding to the VDP-GalNAc is immobilized on the column. Thus, the objective VDP-GalNAc can be obtained at a low cost on a large scale. Dolichosbiflorus agglutinin(DBA), Griffonia simplicifolia agglutinin(GSA), Helix pomatia agglutinin(HPA), etc., are desirably used as the lectin capable of selectively binding to the VDP-GalNAc.

2. 发明专利

JPH06228046A PRODUCTION OF MAGNESIUM HYDROGEN CITRATE PENTAHYDRATE 失效
公开(公告)号：JPH06228046A
公开(公告)日：1994-08-16
申请号：JP1855393
申请日：1993-02-05
申请人： TOMITA PHARMA
发明人： SAKIYAMA TORU , KABAYAMA MINEAKI
IPC分类号： C07C51/41 , C07C51/43 , C07C59/265
摘要： PURPOSE:To provide a production process for magnesium citrate pentahydrate which is excellent in solubilization and storability. CONSTITUTION:Magnesium metal or its salt is allowed to react with citric acid and the reaction product is precipitated to give magnesium hydrogen citrate pentahydrate wherein the citric acid is used in 1.1 to 1.8 mole per mole of magnesium metal or its salt.

3. 发明专利

JPH0568408B2 失效
公开(公告)号：JPH0568408B2
公开(公告)日：1993-09-28
申请号：JP14590386
申请日：1986-06-20
申请人： TOMITA PHARMA
发明人： KABAYAMA MINEAKI , HAYASHI HIRONAGA
IPC分类号： C04B35/18 , C01B33/26

4. 发明专利

JPH0513092B2 失效
公开(公告)号：JPH0513092B2
公开(公告)日：1993-02-19
申请号：JP29021587
申请日：1987-11-16
申请人： TOMITA PHARMA
发明人： KABAYAMA MINEAKI , SUZUKI TAKESHI
IPC分类号： C01F7/02 , A61K33/06 , A61K33/08 , A61P3/00 , B01J20/08

5. 发明专利

JPH01131023A BOEMITELIKE ALUMINUM HYDROXIDE PRODUCTION THEREOF AND PHOSPHORIC ACID ION ADSORBENT FOR ORAL USE CONTAINING IT AS ACTIVE INGREDIENT 失效
公开(公告)号：JPH01131023A
公开(公告)日：1989-05-23
申请号：JP29021587
申请日：1987-11-16
申请人： TOMITA PHARMA
发明人： KABAYAMA MINEAKI , SUZUKI TAKESHI
IPC分类号： C01F7/02 , A61K33/06 , A61K33/08 , A61P3/00 , B01J20/08
摘要： PURPOSE:To readily obtain the title adsorbent outstanding in phosphoric acid adsorptivity, thus useful for e.g., a phosphoric acid ion adsorbent for oral use for patients with renal failure etc., by hydrothermal treatment of noncrystalline Al(OH)3 at specified temperatures. CONSTITUTION:An aqueous dispersion containing 1-10wt.% of noncrystalline Al(OH)3 is subjected to hydrothermal treatment at 60-100 deg.C for 1-5hrs while stirring to obtain the objective boemitelike aluminum hydroxide with the amount of active OH group on the surface of 0.2-1.0meq/g and BET specific surface area of >=200m /g, expressed by the formula (0

6. 发明专利

JPH10328780A COATED SAND FOR CASTING 失效
公开(公告)号：JPH10328780A
公开(公告)日：1998-12-15
申请号：JP13974697
申请日：1997-05-29
申请人： TOYODA AUTOMATIC LOOM WORKS , CHUBU SUKEGAWA KOGYO KK , TOMITA PHARMA
发明人： KOJIMA OSAMU , FUJITA YOSHIO , SANO TOSHIO , YASUDA TSUJIHIKO , KABAYAMA MINEAKI
IPC分类号： B22C1/00 , F02B75/18 , F02F1/10
摘要： PROBLEM TO BE SOLVED: To provide coated sand for casting which can manufacture a casting having extremely small and extremely thin hole part as cast at high temp. while restraining the development of burning, crack and penetration. SOLUTION: The coated sand contains 90-96.5 wt.% high purity silica of =70% 100-200 mesh, =98% SiO2 . The coated sand is used as the core sand for manufacturing a core piece 3 fitted to e.g. a part of a core 1 for water jacket used at the time of manufacturing a Syamese type cylinder block.

7. 发明专利

JPH08198709A ANTIMICROBIAL AND DEODORIZING AGENT 失效
公开(公告)号：JPH08198709A
公开(公告)日：1996-08-06
申请号：JP595895
申请日：1995-01-18
申请人： TOMITA PHARMA
发明人： KABAYAMA MINEAKI , MIHARA MIKIKO
IPC分类号： B01D53/14 , A01N37/36 , A01N59/20 , A61L9/01
摘要： PURPOSE: To obtain an antimicrobial and deodorizing agent containing a copper gluconate as an active ingredient, representing excellent adsorption-removing capability against both N-based and S-based malodor substances, capable of suppressing propagation of bacteria, etc., and excellent also in safety and handleability. CONSTITUTION: This antimicrobial and deodorizing agent contains a copper gluconate as an active ingredient. Concentration of the copper gluconateas as an active ingredient is about 0.5 to 20wt.% in the form of the solution or dispersing agent, about 10 to 80wt.% in the form of tablet and about 10 to 50wt.% in the form of compact. The antimicrobial and deodorizing agent is used together with polyvinyl alcohol, water, ethanol and glycohol to prepare a pack or liquid antimicrobial and deodorizing agent. The agent is also used together with at least one resin among polyethylene, polypropylene and ethylene- vinyl acetate polymer to prepare a sheet agent. The antimicrobial and depdorizing agent has an excellent deodorizing effect, because the copper gluconate in the agent forms a complex ion specifically with an N compound such as ammonia or an S compound such as mercaptan. Further, the copper gluconate prevents organic substances such as proteins from decomposition.

8. 发明专利

JPS632806A RAW MATERIAL FOR MULLITE AND PRODUCTION THEREOF 失效
公开(公告)号：JPS632806A
公开(公告)日：1988-01-07
申请号：JP14590386
申请日：1986-06-20
申请人： TOMITA PHARMA
发明人： KABAYAMA MINEAKI , HAYASHI HIRONAGA
IPC分类号： C04B35/18 , C01B33/26
摘要： PURPOSE:To inexpensively obtain the titled raw material producing a high- strength mullite sintered compact without the need for a high-temp. and high- pressure state by dropping an alkali silicate aq. soln. in the aq. soln. of the homogeneous reaction production of Al salt and alkali aluminate. CONSTITUTION:(A) Al salt such as Al(NO3)3, Al2(SO4)3, AlCl3 and aluminum acetate and (B) alkali aluminate such as sodium aluminate are allowed to react while using (C) about 2-20 weight times water for the theoretical yield of hydrated aluminum silicate to be produced as a reaction medium and regulating pH to 4.5-6.5, and the aq. soln. of a homogeneous reaction product is obtained. Then (D) the aq. soln. of 5-30wt% (expressed in terms of SiO2) concn. of alkali silicate (i.e. sodium silicate) which is regulated to the amount becoming Al2O3/ SiO2=1.0-2.0 molar ratio for the amount of Al2O3 calculated by A and B components is dropped therein at such velocity that the reaction soln. is not allowed to gel and is allowed to react with each other, and thereafter the reaction product is filtered and dried under ventilation and crushed to obtain hydrated aluminum silicate being a raw material for mullite. Thereafter mullite is formed by heat-treating at 1,000-1,200 deg.C.

9. 发明专利

JP2001327860A TREATING AGENT FOR HALOGEN-CONTAINING ACIDIC GAS, METHOD FOR PRODUCING THE SAME AND TREATING METHOD 失效
公开(公告)号：JP2001327860A
公开(公告)日：2001-11-27
申请号：JP2000148124
申请日：2000-05-19
申请人： TOMITA PHARMA
发明人： ONISHI SHOICHI , KABAYAMA MINEAKI , OKUBO AKIRA , MIHARA MIKIKO
IPC分类号： B01D53/68 , B01D53/70 , B01J20/06 , B01J20/08 , B01J20/28 , B01J20/30
摘要： PROBLEM TO BE SOLVED: To provide a treating agent comprising nonpoisonous molding having treating ability comparable to that of a powdery alkali agent in the treatment of halogen-containing acidic gases. SOLUTION: A multiple metal hydroxide having >=30 m2/g BET specific surface area, >=20 ml/10 g apparent bulk density and

10. 发明专利

JPH0574525B2 失效
公开(公告)号：JPH0574525B2
公开(公告)日：1993-10-18
申请号：JP6847987
申请日：1987-03-23
申请人： TOMITA PHARMA , NORITAKE CO LTD
发明人： KABAYAMA MINEAKI , TOMITA TEIZABURO , HIRANO MASANORI , KANI AKIRA
IPC分类号： C04B35/18 , C01B33/26

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