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1. 发明专利

JP2003073245A Composition for oral cavity 审中-公开
标题翻译：口腔用组合物
公开(公告)号：JP2003073245A
公开(公告)日：2003-03-12
申请号：JP2001262916
申请日：2001-08-31
申请人： Sunstar Inc , サンスター株式会社
发明人： NAKAO AKIRA , FUJISAWA KOICHI
IPC分类号： A61K8/00 , A61K8/25 , A61K8/37 , A61Q11/00 , A61K7/16
摘要： PROBLEM TO BE SOLVED: To provide a dentifrice composition which scarcely damages and abrades dentin and has a high stain-removing effect.
SOLUTION: This dentifrice composition contains 0.5 to 5 wt.% of an alkyl glycoside having an alkyl chain length having 8 to 16C carbon atoms and 10 to 30 wt.% of precipitated silica having a weight-average particle size of 9 to 13 μm, oil absorption of 90 to 130 cc/100 g, and a RDA value of ≤70, has a total RDA value of ≥50, scarcely damages and abrades dentin, and has a high stain-removing effect.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供几乎不损伤和磨损牙本质并具有高除污效果的洁牙剂组合物。溶液：该洁齿剂组合物含有0.5〜5重量％的碳原子数为8〜16℃的烷基链长度的烷基糖苷和10〜30重量％的重均粒径为9〜13μm的沉淀二氧化硅，吸油量为90〜130cc / 100g，RDA值<70，总RDA值> 50，几乎不损伤和磨损牙本质，具有高的去污效果。

2. 发明专利

JP2011001387A Anti-endotoxin agent and composition for oral cavity for suppressing periodontal disease containing the same 有权
标题翻译：用于抑制含有其的周围疾病的口腔内胶原剂和组合物
公开(公告)号：JP2011001387A
公开(公告)日：2011-01-06
申请号：JP2010227386
申请日：2010-10-07
申请人： Sunstar Inc , サンスター株式会社
发明人： INUBUSHI JUNYA , NAKAO AKIRA , SAITO TORU
IPC分类号： A61K8/42 , A61K8/34 , A61K8/40 , A61K8/44 , A61K31/164 , A61P1/02 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide an anti-endotoxin agent inhibiting LPS activity and effective on preventing or treating not only periodontal diseases but also endotoxin shock symptoms etc. caused by bacterial infection; and to provide an inhibitor for the oral cavity for suppressing periodontal diseases containing the same.SOLUTION: The anti-endotoxin agent includes an active component of a surfactant having an amide structure in the molecule (e.g. a fatty acid monoethanolamide, fatty acid diethanolamide, fatty acid amide betaine, fatty acid amide propyl betaine, N-acylamino acid salt and N-coconut oil fatty acid acyl L-arginine ethyl dl-pyrrolidone carboxylic acid salt). The composition for the oral cavity for suppressing periodontal diseases including an effective amount of the anti-endotoxin agent, is also provided.
摘要翻译：要解决的问题：提供抑制LPS活性的抗内毒素剂，并且有效地预防或治疗由细菌感染引起的牙周病，还有内毒素休克症状等。并提供用于抑制含有该牙周病的牙周病的口腔抑制剂。溶解性：抗内毒素剂包括在分子中具有酰胺结构的表面活性剂的活性成分（例如脂肪酸单乙醇酰胺，脂肪酸二乙醇酰胺，脂肪酸酰胺甜菜碱，脂肪酸酰胺丙基甜菜碱，N-酰基氨基酸盐和N-椰子油脂肪酸酰基L-精氨酸乙基dl-吡咯烷酮羧酸盐）。还提供了用于抑制牙周病的口腔用组合物，包括有效量的抗内毒素剂。

3. 发明专利

JP2005104913A Anti-endotoxin agent and composition for oral cavity for suppression of periodontal disease containing the same 有权
标题翻译：用于抑制含有其的周围疾病的口腔内胶原剂和组合物
公开(公告)号：JP2005104913A
公开(公告)日：2005-04-21
申请号：JP2003341229
申请日：2003-09-30
申请人： Sunstar Inc , サンスター株式会社
发明人： INUBUSHI JUNYA , NAKAO AKIRA , SAITO TORU
IPC分类号： A61K47/08 , A61K31/164 , A61K31/198 , A61K31/205 , A61K31/223 , A61K31/4425 , A61K47/10 , A61K47/44 , A61P1/02 , A61P31/04 , A61P39/02 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide an anti-endotoxin agent inhibiting activity of LPS and effective for prophylaxis or treatment of periodontal diseases and further effective for prophylaxis or treatment of endotoxin shock symptom, etc., caused by bacterial infection and an inhibitor for oral cavity for suppression of periodontal diseases containing the anti-endotoxin.
SOLUTION: The anti-endotoxin agent comprises a surfactant (e.g. a fatty acid monoethanolamide, a fatty acid amide betaine, a fatty acid amidepropyl betaine, an N-acylamino acid salt or an N-coconut oil fatty acid acyl L-arginineethyl-dl-pyrrolidonecarboxylic acid salt) having an amide structure in a molecule as an active ingredient. The composition for oral cavity for suppression of periodontal diseases including an effective dose of the anti-endotoxin agent.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供抑制LPS的活性的抗内毒素剂，并有效预防或治疗牙周病，进一步有效预防或治疗由细菌感染引起的内毒素休克症状等，以及抑制剂用于抑制含有抗内毒素的牙周病的口腔。抗内毒素剂包括表面活性剂（例如脂肪酸单乙醇酰胺，脂肪酸酰胺甜菜碱，脂肪酸酰胺丙基甜菜碱，N-酰基氨基酸盐或N-椰子油脂肪酸酰基L-精氨乙基 -d1-吡咯烷酮羧酸盐）作为有效成分。用于抑制牙周病的口腔组合物，包括有效剂量的抗内毒素剂。版权所有（C）2005，JPO＆NCIPI

4. 发明专利

JP2009292744A Liquid composition for oral cavity 审中-公开
标题翻译：口腔用液体组合物
公开(公告)号：JP2009292744A
公开(公告)日：2009-12-17
申请号：JP2008145505
申请日：2008-06-03
申请人： Sunstar Inc , サンスター株式会社
发明人： NAKAO AKIRA , HASEGAWA MORITAKA
IPC分类号： A61K8/73 , A61K8/02 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a liquid composition for oral cavities, in which water-insoluble ingredients such as a perfume and an active ingredient are transparently or homogeneously dispersed, and which does not contain ethanol or contains ethanol in a small amount. SOLUTION: Provided is the liquid composition for oral cavities, such as a mouth-washing agent, a mouth wash, or a mouth spray, which contains fine crystal cellulose coated with a water-soluble substance such as a water-soluble polymer, in which a perfume, an oil-soluble active ingredient, and the like are transparently or homogeneously dispersed, and which contains ethanol in a small amount. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种口腔用液体组合物，其中水不溶性成分如香料和活性成分透明或均匀分散，不含乙醇或含有少量乙醇。解决方案：提供了包含用水溶性物质如水溶性聚合物涂覆的精细晶体纤维的口腔液体组合物，例如口腔清洁剂，漱口剂或口腔喷雾剂其中香料，油溶性活性成分等透明或均匀分散，并含有少量的乙醇。版权所有（C）2010，JPO＆INPIT

5. 发明专利

JP2004203894A Composition for oral cavity 审中-公开
标题翻译：口腔组成
公开(公告)号：JP2004203894A
公开(公告)日：2004-07-22
申请号：JP2004115468
申请日：2004-04-09
申请人： Sunstar Inc , サンスター株式会社
发明人： TAKATSUKA TSUTOMU , NAKAO AKIRA
IPC分类号： A61K8/00 , A61K8/34 , A61K8/86 , A61Q11/00 , A61K7/16
摘要： PROBLEM TO BE SOLVED: To obtain a composition for oral cavity, containing Zn, resisting dental caries and preventing tartar and halitosis, wherein the composition for oral cavity is improved in bitter taste and metallic taste of Zn and has good sense of use.
SOLUTION: This composition for oral cavity and containing a Zn compound is improved in metallic taste of the Zn compound by compounding a polyhydric alcohol and anethole at a certain ratio. One or more selected from sorbitol, xylitol, glycerol, polyethylene glycol, maltitol and palatinose are illustrated as the polyhydric alcohol. The compounding amount of the anethole is preferably 0.01-1 wt.%. Preferably, a fluoride compound is also compounded at a ratio of 50-10,000 ppm when calculated as F.
COPYRIGHT: (C)2004,JPO&NCIPI
摘要翻译：待解决的问题：为了获得含有Zn的抗口腔龋齿和防止牙垢和口臭的口腔用组合物，其口腔组合物具有改善的苦味和金属味，并且具有良好的使用感。解决方案：通过以一定的比例配合多元醇和茴香脑，这种用于口腔并含有Zn化合物的组合物改善了Zn化合物的金属味道。选自山梨糖醇，木糖醇，甘油，聚乙二醇，麦芽糖醇和帕拉金糖中的一种或多种作为多元醇进行说明。茴香脑的配合量优选为0.01〜1重量％。优选地，当以F计算时，氟化合物也以50-10,000ppm的比例混合。版权所有（C）2004，JPO＆NCIPI

6. 发明专利

JP2008120753A Liquid composition for oral cavity 审中-公开
标题翻译：口腔用液体组合物
公开(公告)号：JP2008120753A
公开(公告)日：2008-05-29
申请号：JP2006308478
申请日：2006-11-14
申请人： Sunstar Inc , サンスター株式会社
发明人： WATANABE RIE , NAKAO AKIRA
IPC分类号： A61K8/40 , A61K8/67 , A61K8/73 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a liquid composition for an oral cavity excellent in the remaining property of an active ingredient in the oral cavity.
SOLUTION: This liquid composition for the oral cavity prepared by blending 0.005 to 0.5 wt.% cetylpyridinium chloride and/or vitamins and 0.01 to 1.0 wt.% non-anionic water soluble polymer, and adjusting the viscosity of the composition so as to become 10 to 500 mPa s is provided with that the non-anionic water soluble polymer in the liquid composition for the oral cavity is hydroxycellulose, and the vitamins are pyridoxines and/or a vitamin E ester.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供口腔中活性成分的剩余性质优异的口腔用液体组合物。解决方案：该口腔用液体组合物通过混合0.005-0.5重量％氯化十六烷基吡啶和/或维生素和0.01-1.0重量％的非阴离子水溶性聚合物制备，并调节组合物的粘度，使得提供了用于口腔液体组合物中的非阴离子水溶性聚合物是羟基纤维素，并且维生素是吡哆醇和/或维生素E酯的10-500mPa·s。版权所有（C）2008，JPO＆INPIT

7. 发明专利

JP2008169165A Polishing material for pmtc 有权
标题翻译： PMTC抛光材料
公开(公告)号：JP2008169165A
公开(公告)日：2008-07-24
申请号：JP2007005237
申请日：2007-01-12
申请人： Sunstar Inc , サンスター株式会社
发明人： NAKAO AKIRA , INOUE ATSUSHI , FUJISAWA KOICHI
IPC分类号： A61K6/00 , A61C17/00 , A61K8/25
摘要： PROBLEM TO BE SOLVED: To provide a polishing material for PMTC (professional mechanical tooth cleaning) effective for removing biofilms and stains on the tooth surface or between the teeth without giving excessive roughening to the tooth surface.
SOLUTION: The polishing material for PMTC is produced by compounding (A) a silicic anhydride having an average particle diameter of 1-5 μm and an oil absorption of 30-70 mL/100 g with (B) a silicic anhydride having an average particle diameter of 6-12 μm and an oil absorption of 100-130 mL/100 g, wherein the compounding ratio of the silicic anhydride (A) to (B) is 1:3 to 2:1, the content of the silicic anhydride (A) is ≥10 wt.%, that of the silicic anhydride (B) is ≥10 wt.%, and the sum of the compounding amount of the silicic anhydrides (A) and (B) is 35-80 wt.%. A polishing material for PMTC free from the damaging trouble on the tooth surface can be produced by the method.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供用于除去齿表面或齿之间的生物膜和污渍的PMTC（专业机械牙齿清洁）的抛光材料，而不会对牙齿表面产生过度的粗糙化。＆lt; P＆gt;解决方案：PMTC用抛光材料是通过（A）平均粒径为1-5μm，吸油量为30-70mL / 100g的硅酸酐与（B）具有平均粒径为6〜12μm，吸油量为100〜130mL / 100g，其中，所述硅酸酐（A）与（B）的配合比例为1:3〜2:1，硅酸酐（A）的含量≥10重量％，硅酸酐（B）的重量比≥10重量％，硅酸酐（A）和（B）的配混量之和为35〜80重量％％。可以通过该方法制造不含牙齿表面损伤的PMTC的抛光材料。版权所有（C）2008，JPO＆INPIT

8. 发明专利

JP2007084471A Composition for oral cavity and method of selecting product for oral cavity 审中-公开
标题翻译：用于口腔的组合物和选择用于口腔的产品的方法
公开(公告)号：JP2007084471A
公开(公告)日：2007-04-05
申请号：JP2005273948
申请日：2005-09-21
申请人： Sunstar Inc , サンスター株式会社
发明人： NAKAO AKIRA
IPC分类号： A61K8/00 , A61K8/20 , A61K8/24 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/40 , A61K8/43 , A61K8/44 , A61K8/86 , A61K8/97 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a composition for oral cavity, having preventing and suppressing effects for dental caries, periodontosis and the like and excellent in refrigerant feeling, and to provide a method for selecting the most proper product for oral cavity, corresponding to oral cavity state and symptoms even if having no expertise. SOLUTION: The composition for oral cavity contains one or more antibacterial agent selected from a group consisting of cetylpyridinium chloride, a chlorhexidine salt, hexetidine, dequalinium chloride, benzalkonium chloride and benzethonium chloride, and Mentha arvensis extracts. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：解决问题：提供一种口腔用组合物，具有预防和抑制龋齿，牙周病等的作用，并且制冷剂感觉优异，并且提供了选择口腔最合适的产品的方法，对应于口腔状态和症状，即使没有专业知识。口腔用组合物含有一种或多种选自氯化十六烷基吡啶，氯己定盐，己啶胺，氯化癸草胺，苯扎氯铵和苄索氯铵以及薄荷提取物的抗菌剂。版权所有（C）2007，JPO＆INPIT

9. 发明专利

JP2003073282A Composition for oral cavity application 审中-公开
标题翻译：口腔应用组合物
公开(公告)号：JP2003073282A
公开(公告)日：2003-03-12
申请号：JP2001262918
申请日：2001-08-31
申请人： Sunstar Inc , サンスター株式会社
发明人： NAKAO AKIRA , MARUYAMA TAKASHI
IPC分类号： A61K47/08 , A61K8/00 , A61K8/35 , A61K33/00 , A61K47/10 , A61K47/22 , A61P1/02 , A61Q11/00 , A61K7/16
摘要： PROBLEM TO BE SOLVED: To provide a composition for oral cavity application having decreased bitter taste of potassium nitrate.
SOLUTION: The composition for oral cavity application is produced by compounding potassium nitrate with anethole and further with one or more components selected from cineole, vanillin, citronellal and cinnamic aldehyde.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供具有降低的硝酸钾苦味的口腔应用组合物。解决方案：通过将硝酸钾与茴香脑混合，再与一种或多种选自桉树脑，香草醛，香茅醛和肉桂醛的成分混合制备口腔用组合物。

10. 发明专利

JP2003073246A Composition for oral cavity 审中-公开
标题翻译：口腔用组合物
公开(公告)号：JP2003073246A
公开(公告)日：2003-03-12
申请号：JP2001262917
申请日：2001-08-31
申请人： Sunstar Inc , サンスター株式会社
发明人： NAKAO AKIRA , TAKATSUKA TSUTOMU
IPC分类号： A61K8/21 , A61K8/34 , A61K8/36 , A61K8/365 , A61Q11/00 , A61K7/18
摘要： PROBLEM TO BE SOLVED: To obtain a composition for the oral cavity for alleviating hyperesthesia of exposed dentin and promoting recalcification.
SOLUTION: This composition for the oral cavity comprises potassium nitrate and reduced paratinose, alleviates hyperesthesia and promotes recalcification.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：获得口腔用组合物，以减轻暴露牙质的感觉异常并促进再钙化。解决方案：该口腔用组合物包含硝酸钾和减少的副抗白血病，减轻感觉过敏并促进再钙化。

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