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1. 发明专利

JP2009084278A Oral composition 有权
标题翻译：口腔组成
公开(公告)号：JP2009084278A
公开(公告)日：2009-04-23
申请号：JP2008234663
申请日：2008-09-12
申请人： Shizuoka Prefecture , Sunstar Inc , サンスター株式会社 , 静岡県
发明人： NISHIJIMA NANAE , FUJII AKIKO , FUJISAWA KOICHI , OTA YOJIRO
IPC分类号： A61K47/36 , A61K31/047 , A61K47/04 , A61P1/02
摘要： PROBLEM TO BE SOLVED: To provide an oral composition having improved preservation stability, a micro-gel preparation having excellent ratainability in the mouth. SOLUTION: Micro-gel particles are prepared by adding gellan gum of 0.3 to 0.4% by weight as a gelling agent and 1 to 6 mmol of a divalent metal ion per 1 g of the gellan gum as a crosslinking agent. The oral composition having excellent retainability in the mouth and improved preservation stability such as syneresis and appearance is characterized by being produced by constructing a preparation with the assembly of the micro-gel particles. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：为了提供具有改善的保存稳定性的口服组合物，在口腔中具有优异的可溶性的微凝胶制剂。解决方案：通过加入0.3至0.4重量％的凝胶胶作为胶凝剂和1至6mmol二价金属离子/ 1g作为交联剂的结冷胶，制备微凝胶颗粒。具有优异的口腔保持性和提高的保存稳定性如脱水收缩和外观的口腔组合物的特征在于通过构建具有微凝胶颗粒的组装的制剂来制备。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2009084277A Dentifrice composition 有权
标题翻译： DENTIFRICE组成
公开(公告)号：JP2009084277A
公开(公告)日：2009-04-23
申请号：JP2008234662
申请日：2008-09-12
申请人： Shizuoka Prefecture , Sunstar Inc , サンスター株式会社 , 静岡県
发明人： FUJISAWA KOICHI , OHARA TAKESHI , KANAMORI TAKEYUKI , OTA YOJIRO
IPC分类号： A61K8/44 , A61K8/46 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a low stimulating dentifrice composition while formulating laurylsulfate in order to give moderate foamability.
SOLUTION: (A) 0.2-0.7 wt.% of laurylsulfate and (B) 0.2-0.7 wt.% of fatty acid amidopropylbetaine are formulated at a compounding ratio of (A):(B)=1:0.5-1:2, thereby the dentifrice composition with moderate foamability and reduced stimulation to an oral cavity is made.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：为了提供适度的起泡性，提供低刺激性洁齿剂组合物同时配制月桂基硫酸盐。解决方案：（A）0.2-0.7重量％的月桂基硫酸盐和（B）0.2-0.7重量％的脂肪酸酰胺丙基甜菜碱以（A）：（B）= 1：0.5-1的配混比配制：2，从而制成具有适度发泡性和减少对口腔刺激的洁齿剂组合物。版权所有（C）2009，JPO＆INPIT

3. 发明专利

JP2011074030A Microgel for oral cavity 审中-公开
标题翻译：口服口腔的MICROGEL
公开(公告)号：JP2011074030A
公开(公告)日：2011-04-14
申请号：JP2009228885
申请日：2009-09-30
申请人： Sunstar Inc , サンスター株式会社
发明人： KURAMITSU SHOHEI , FUJISAWA KOICHI
IPC分类号： A61K8/40 , A61K8/43 , A61K8/49 , A61K8/73 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a microgel for the oral cavity which has a low fluidity, is easy and safe to use, and efficiently delivers effective components.
SOLUTION: The microgel for the oral cavity includes a cationic bactericide and agar. The content of the agar is 0.3-3 mass%. The microgel for the oral cavity (or a composition for the oral cavity containing the microgel) is easy to be adsorbed on the surface of the teeth, hard to drip, easily penetrates between teeth and teeth and gums. The cationic bactericide is easy to disperse and elute.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：为了提供具有低流动性的口腔微凝胶，易于使用和安全使用，并有效地提供有效的组分。解决方案：口腔微凝胶包括阳离子杀菌剂和琼脂。琼脂的含量为0.3〜3质量％。用于口腔的微凝胶（或含有微凝胶的口腔用组合物）容易吸附在牙齿表面上，难以滴落，容易渗透牙齿与牙齿和牙龈之间。阳离子杀菌剂易于分散和洗脱。版权所有（C）2011，JPO＆INPIT

4. 发明专利

JP2003081796A Composition for the oral cavity 有权
标题翻译：口腔的组成
公开(公告)号：JP2003081796A
公开(公告)日：2003-03-19
申请号：JP2002196716
申请日：2002-07-05
申请人： Sunstar Inc , サンスター株式会社
发明人： FUJISAWA KOICHI
IPC分类号： A61K8/00 , A61K8/25 , A61K8/46 , A61Q11/00 , A61K7/16
摘要： PROBLEM TO BE SOLVED: To provide a composition for the oral cavity having a stein formation inhibiting effect together with a stein adhesion suppressing effect, capable of effectively preventing coloration of the tooth.
SOLUTION: This composition for the oral cavity includes 0.01-5 wt.% of one or more kinds of sulfosuccinate based surfactant expressed in general formula (1) and 0.5-10 wt.% of an abrasive precipitated silica having 50 percentile (d
50 ) ≤5 μm and 90 percentile (d
90 ) ≤15 μm of particle diameter and RDA (Radioactive Dentin Abrasion) value ≥120. [In the formula either one of X
1 and X
2 is R
1 O-(AO)
n - or R
1 CO-B-(AO)
n - and the other is M
2 O-, M
1 and M
2 are each same or different H, an alkali metal, an alkaline earth metal, ammonium or an alkanol amine, R
1 is a 8-22C alkyl or alkenyl group, AO is a 2-3C oxyalkylene group, the average added mole numbers n is 0-20, B is -NH- or a 2-3C monoalkanol amine residue].
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供一种能够有效防止牙齿着色的具有阻骨形成抑制作用的口腔用组合物和骨粘合抑制效果。解决方案：该口腔用组合物包含0.01-5重量％的一种或多种通式（1）表示的磺基琥珀酸盐基表面活性剂和0.5-10重量％的具有50百分位数（d50） =5μm，90％（d90）<=15μm的粒径和RDA（放射性牙质磨损）值> = 120。 [式中，X 1，X 2中的任一个为R 1 O-（AO）n - 或R 1 CO-B-（AO）n - ，另一个为M 2 O-，M 1和M 2各自相同或不同。金属，碱土金属，铵或烷醇胺，R1为8-22C烷基或烯基，AO为2-3C氧化烯基，平均加成摩尔数n为0-20，B为-NH-或 2-3C单链烷醇胺残基]。

5. 发明专利

JP2003081797A Composition for the oral cavity 有权
标题翻译：口腔的组成
公开(公告)号：JP2003081797A
公开(公告)日：2003-03-19
申请号：JP2002196718
申请日：2002-07-05
申请人： Sunstar Inc , サンスター株式会社
发明人： FUJISAWA KOICHI
IPC分类号： A61K8/00 , A61K8/35 , A61K8/37 , A61K8/46 , A61K8/49 , A61Q11/00 , A61K7/16
摘要： PROBLEM TO BE SOLVED: To provide a composition for the oral cavity including a sulfosuccinate based surfactant to effectively inhibit formation of stein and improving bitterness originating from the sulfosuccinate based surfactant and the odor of the surfactant.
SOLUTION: This composition for the oral cavity comprises 0.01-5 wt.% of the sulfosuccinate based surfactant expressed by general formula (1), 0.01-1 wt.% of saccharin sodium and stevioside mixed in the weight ratio of saccharin sodium:stevioside=1:1 to 8:1, and one or more kinds of compound selected from vanillin, anethole and benzylsuccinate. [In the formula either one of X
1 and X
2 is R
1 O-(AO)
n or R
1 CO-B-(AO)
n - and the other is M
2 O-, M
1 and M
2 are each same or different H, an alkali metal or the like, R
1 is a 8-22C alkyl or alkenyl group, AO is a 2-3C oxyalkylene group, the average added mole numbers n is 0-20, B is -NH- or the like].
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供一种口腔用组合物，其包含磺基琥珀酸酯类表面活性剂，以有效抑制肌醇蛋白形成，改善由磺基琥珀酸酯类表面活性剂引起的苦味和表面活性剂的气味。解决方案：该口腔用组合物含有0.01-5重量％的由通式（1）表示的磺基琥珀酸酯系表面活性剂，0.01〜1重量％的糖精钠和甜菊苷以糖精钠重量比：甜菊苷= 1：1至8：1，以及一种或多种选自香草醛，茴香脑和苄基琥珀酸盐的化合物。 [式中X 1和X 2中的任一个为R 1 O-（AO）n或R 1 CO-B-（AO）n - ，另一个为M O O-，M 1和M 2各自相同或不同。 R1为8-22C烷基或链烯基，AO为2-3C氧化烯基，平均加成摩尔数n为0-20，B为-NH-等]。

6. 发明专利

JP2011051927A Composition for oral cavity 审中-公开
标题翻译：口腔组成
公开(公告)号：JP2011051927A
公开(公告)日：2011-03-17
申请号：JP2009201834
申请日：2009-09-01
申请人： Sunstar Inc , サンスター株式会社
发明人： FUJISAWA KOICHI , FUJII AKIKO
IPC分类号： A61K8/73 , A61K8/19 , A61K8/24 , A61K8/25 , A61K8/29 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a composition for oral cavities which contains a sparingly water-soluble powdery component, is used for applicator-integrated containers, and can simply and stably be delivered to application parts of the applicator-integrated containers in an effective amount every time. SOLUTION: The composition for oral cavities for use in applicator-integrated containers includes 0.1-10 mass% of (A) a sparingly water-soluble powdery component, 0.5-5 mass% of (B) xanthan gum, and ≥50 mass% of (C) water. As it contains xanthan gum as a thickener, the composition for oral cavities disperses the sparingly water-soluble powdery component in a stable manner and has a viscosity behavior appropriate for ejecting a chemical from applicator-integrated containers. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：为了提供含有微溶水性粉末成分的口腔用组合物，用于涂抹器一体化容器，并且可以简单且稳定地将其输送到施用器集成容器的施用部件中每次有效量。解决方案：用于涂抹器一体化容器的口腔用组合物包含0.1-10质量％的（A）微水溶性粉末组分，0.5-5质量％（B）黄原胶，和≥50 （C）水的质量％。由于其含有黄原胶作为增稠剂，口腔用组合物以稳定的方式分散微溶于水的粉末状组分，并具有适合于从涂抹器集成的容器喷射化学品的粘度特性。版权所有（C）2011，JPO＆INPIT

7. 发明专利

JP2010280612A Composition for oral cavity 有权
标题翻译：口腔组成
公开(公告)号：JP2010280612A
公开(公告)日：2010-12-16
申请号：JP2009135471
申请日：2009-06-04
申请人： Sunstar Inc , サンスター株式会社
发明人： TSUMURA YUKAKO , FUJII AKIKO , FUJISAWA KOICHI
IPC分类号： A61K8/49 , A61J1/10 , A61K8/34 , A61K8/43 , A61K8/73 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a composition for oral cavities, used for applicator integration type containers, which can simply and stably be supplied to the coating portions of the applicator integration type containers in effective amounts at every time and contains a cationic anti-microbial agent.
SOLUTION: This composition for oral cavities, used for applicator integration type containers, containing a cationic anti-microbial agent, includes (I) the following (A) to (C): (A) 0.05 to 0.5 mass% of a cationic anti-microbial agent, (B) 0.05 to 2.5 mass% of at least one nonionic thickener selected from the group consisting of hydroxyethylcellulose, hydroxypropylmethylcellulose and methylcellulose, and (C) ≥50 mass% of water, and has (II) a viscosity of 500 to 15,000 mPa s at a shear speed of 8 s
-1 .
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供一种用于涂抹器一体化型容器的口腔用组合物，其可以简单且稳定地每次有效量地向敷料器一体型容器的涂布部分供给并含有阳离子抗微生物剂。解决方案：用于含有阳离子抗微生物剂的涂布器一体型容器的口腔用组合物包括（I）以下（A）〜（C）：（A）0.05〜0.5质量％阳离子抗微生物剂，（B）0.05〜2.5质量％的选自羟乙基纤维素，羟丙基甲基纤维素和甲基纤维素的至少一种非离子型增稠剂，（C）≥50质量％的水，并且（II）在8s -1的剪切速度下为500至15,000mPa·s。版权所有（C）2011，JPO＆INPIT

8. 发明专利

JP2009084279A Composition for oral cavity 有权
标题翻译：口腔用组合物
公开(公告)号：JP2009084279A
公开(公告)日：2009-04-23
申请号：JP2008234664
申请日：2008-09-12
申请人： Shizuoka Prefecture , Sunstar Inc , サンスター株式会社 , 静岡県
发明人： FUJII AKIKO , FUJISAWA KOICHI , NISHIJIMA NANAE , OTA YOJIRO
IPC分类号： A61K8/60 , A61K8/02 , A61K8/37 , A61K8/73 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a liquid or liquid-like composition for the oral cavity having an excellent effect of suppressing or preventing dryness in the oral cavity. SOLUTION: The liquid or liquid-like composition for the oral cavity having an excellent effect of suppressing or preventing dryness in the oral cavity is obtained by making the blending ratio of water 80 wt.% or higher in a composition of a carbohydrate derivative of α,α-trehalose, a water-soluble polymer, methyl paraoxybenzoate and water. Especially when xanthan gum is used as the water-soluble polymer, an excellent effect is obtained. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：为口腔提供液体或液体状组合物，具有抑制或预防口腔干燥的优异效果。解决方案：通过使糖的组合物中80重量％以上的水的配合比例，可以获得口腔中具有优异抑制或预防口腔干燥效果的口腔液状或液状组合物衍生物α，α-海藻糖，水溶性聚合物，对羟基苯甲酸甲酯和水。特别是当使用黄原胶作为水溶性聚合物时，获得了极好的效果。版权所有（C）2009，JPO＆INPIT

9. 发明专利

JP2008169165A Polishing material for pmtc 有权
标题翻译： PMTC抛光材料
公开(公告)号：JP2008169165A
公开(公告)日：2008-07-24
申请号：JP2007005237
申请日：2007-01-12
申请人： Sunstar Inc , サンスター株式会社
发明人： NAKAO AKIRA , INOUE ATSUSHI , FUJISAWA KOICHI
IPC分类号： A61K6/00 , A61C17/00 , A61K8/25
摘要： PROBLEM TO BE SOLVED: To provide a polishing material for PMTC (professional mechanical tooth cleaning) effective for removing biofilms and stains on the tooth surface or between the teeth without giving excessive roughening to the tooth surface.
SOLUTION: The polishing material for PMTC is produced by compounding (A) a silicic anhydride having an average particle diameter of 1-5 μm and an oil absorption of 30-70 mL/100 g with (B) a silicic anhydride having an average particle diameter of 6-12 μm and an oil absorption of 100-130 mL/100 g, wherein the compounding ratio of the silicic anhydride (A) to (B) is 1:3 to 2:1, the content of the silicic anhydride (A) is ≥10 wt.%, that of the silicic anhydride (B) is ≥10 wt.%, and the sum of the compounding amount of the silicic anhydrides (A) and (B) is 35-80 wt.%. A polishing material for PMTC free from the damaging trouble on the tooth surface can be produced by the method.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供用于除去齿表面或齿之间的生物膜和污渍的PMTC（专业机械牙齿清洁）的抛光材料，而不会对牙齿表面产生过度的粗糙化。＆lt; P＆gt;解决方案：PMTC用抛光材料是通过（A）平均粒径为1-5μm，吸油量为30-70mL / 100g的硅酸酐与（B）具有平均粒径为6〜12μm，吸油量为100〜130mL / 100g，其中，所述硅酸酐（A）与（B）的配合比例为1:3〜2:1，硅酸酐（A）的含量≥10重量％，硅酸酐（B）的重量比≥10重量％，硅酸酐（A）和（B）的配混量之和为35〜80重量％％。可以通过该方法制造不含牙齿表面损伤的PMTC的抛光材料。版权所有（C）2008，JPO＆INPIT

10. 发明专利

JP2006169226A Chewing gum for inhibiting teeth from being attached with stain 审中-公开
标题翻译：用于抑制与粘附在一起的牙齿的茶叶
公开(公告)号：JP2006169226A
公开(公告)日：2006-06-29
申请号：JP2004382560
申请日：2004-12-14
申请人： Sunstar Inc , サンスター株式会社
发明人： NAKAGAWA MARIKO , FUJISAWA KOICHI
IPC分类号： A61K38/17 , A23G4/00 , A61K8/00 , A61K9/68 , A61P1/02 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a chewing gum inhibiting teeth from being attached with a stain and capable of removing polyphenols becoming a cause of the stain and drifting in an oral cavity such as in saliva.
SOLUTION: This chewing gum inhibiting the teeth from being attached with the stain is provided by blending gelatin or collagen which are proteins having >15% proline and histidine in their amino acid compositions, adsorbing the polyphenols drifting in the oral cavity with high selectivity.
COPYRIGHT: (C)2006,JPO&NCIPI

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