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1. 发明专利

JP2013075914A Calcium antagonist 审中-公开
标题翻译： CALCIUM ANTAGONIST
公开(公告)号：JP2013075914A
公开(公告)日：2013-04-25
申请号：JP2013006120
申请日：2013-01-17
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： MORIMITSU KOJIRO , KUBOTA KIKUE , HIRUMA MIHOKO
IPC分类号： A61K31/343 , A23L1/30 , A61K31/365 , A61K31/366 , A61P3/14 , A61P9/00 , A61P9/06 , A61P9/10 , A61P9/12 , A61P17/00 , A61P21/02 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a novel calcium antagonist capable of reducing or preventing various adverse effects with which intracellular calcium ions are associated, and particularly to provide a calcium antagonist capable of being simply obtained and being easily mass-produced.SOLUTION: The calcium antagonist includes at least one compound as an active constituent selected from the group consisting of compounds expressed by formulas (1) to (3), wherein Ris an alkylidene group having 1 to 10 carbon atoms and Ris an alkoxy group having 1 to 3 carbon atoms. Additionally, an antiarrhythmic drug, a vasorelaxant, an anti-cerebral vasospasm and the like comprising the calcium antagonist as the active constituent are provided.
摘要翻译：待解决的问题：提供能够减少或预防与细胞内钙离子相关联的各种不利影响的新型钙拮抗剂，特别是提供能够简单获得并容易批量生产的钙拮抗剂。解决方案：钙拮抗剂包括至少一种选自由式（1）至（3）表示的化合物的活性成分的化合物，其中R 1 是具有1至10个碳原子的亚烷基，R 3是具有1至3个碳原子的烷氧基。此外，提供了包含钙拮抗剂作为活性成分的抗心律不齐药物，血管舒张剂，抗脑血管痉挛等。版权所有（C）2013，JPO＆INPIT

2. 发明专利

JP2013064023A Calcium antagonist 有权
标题翻译： CALCIUM ANTAGONIST
公开(公告)号：JP2013064023A
公开(公告)日：2013-04-11
申请号：JP2013006121
申请日：2013-01-17
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： MORIMITSU KOJIRO , KUBOTA KIKUE , HIRUMA MIHOKO
IPC分类号： A61K31/341 , A61P9/06 , A61P9/10 , A61P9/12 , A61P25/08 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a novel calcium antagonist capable of reducing or preventing various adverse effects involving intracecullar calcium ion, particularly, a calcium antagonist which is more easily available and can easily attain mass production.SOLUTION: The calcium antagonist contains a compound represented by formula (1) (wherein R1 and R2 each independently represent a 1-3C linear alkyl, and R3 represents a 1-10C linear alkylidene) as an active ingredient. Further, an anti-arrhythmic agent, a vascular relaxant, a cerebral vascular antispasmodic, and the like each including the calcium antagonist as an active ingredient are provided.
摘要翻译：待解决的问题：提供能够减少或预防涉及脑内钙离子的各种副作用的新颖的钙拮抗剂，特别是更易于获得并可容易地达到批量生产的钙拮抗剂。解决方案：钙拮抗剂含有式（1）表示的化合物（其中R 1和R 2各自独立地表示1-3个直链烷基，R 3表示1-10个碳原子的直链亚烷基）作为活性成分。此外，提供了包含钙拮抗剂作为活性成分的抗心律变化剂，血管松弛剂，脑血管解痉药等。版权所有（C）2013，JPO＆INPIT

3. 发明专利

JP2013082738A Platelet aggregation inhibitor 审中-公开
标题翻译： PLATELET聚合抑制剂
公开(公告)号：JP2013082738A
公开(公告)日：2013-05-09
申请号：JP2013005462
申请日：2013-01-16
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： MORIMITSU KOJIRO , KUBOTA KIKUE , HIRUMA MIHOKO
IPC分类号： A61K31/352 , A61K31/353 , A61P7/02 , C07D311/18 , C07D311/20
摘要： PROBLEM TO BE SOLVED: To provide a platelet aggregation inhibitor capable of relieving or preventing various symptoms caused by aggregation of platelets, particularly available more conveniently, and capable of being mass-produced easily.SOLUTION: The platelet aggregation inhibitor includes a compound represented by formula (1) as an active ingredient. There are further provided blood flow improving agents and antithrombotic agents each containing the platelet aggregation inhibitor as an active ingredient.
摘要翻译：待解决的问题：提供能够缓解或预防由血小板聚集引起的各种症状的血小板聚集抑制剂，特别可以更方便地获得并且能够容易地批量生产。
解决方案：血小板聚集抑制剂包括由式（1）表示的化合物作为活性成分。另外提供各自含有血小板聚集抑制剂作为有效成分的血流量改善剂和抗血栓形成剂。版权所有（C）2013，JPO＆INPIT

4. 发明专利

JP2013067659A Platelet aggregation inhibitor 有权
标题翻译： PLATELET聚合抑制剂
公开(公告)号：JP2013067659A
公开(公告)日：2013-04-18
申请号：JP2013002210
申请日：2013-01-10
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： HIRUMA MIHOKO , TAKAI EIJI , MORIMITSU KOJIRO , KUBOTA KIKUE
IPC分类号： A61K31/201 , A23L1/30 , A23L2/52 , A61P7/02 , A61P9/00
摘要： PROBLEM TO BE SOLVED: To provide a new platelet aggregation inhibitor which can reduce or prevent various symptoms caused by the aggregation of platelets, and particularly, to provide a platelet aggregation inhibitor which can be more easily obtained and whose mass production can be easily achieved as well.SOLUTION: The platelet aggregation inhibitor includes at least one selected from 2-decenoic acid, 4-decenoic acid and 9-decenoic acid as an active constituent. Further, a blood flow improving agent or an antithrombotic agent using the platelet aggregation inhibitor as an active constituent is provided.
摘要翻译：要解决的问题：提供一种可以减少或预防血小板聚集引起的各种症状的新型血小板聚集抑制剂，特别是提供可以更容易地获得并且其批量生产的血小板聚集抑制剂也很容易实现。解决方案：血小板聚集抑制剂包括选自2-癸烯酸，4-癸烯酸和9-癸烯酸中的至少一种作为活性成分。此外，提供使用血小板聚集抑制剂作为活性成分的血流改善剂或抗血栓形成剂。版权所有（C）2013，JPO＆INPIT

5. 发明专利

JP2014140373A Method for adding active oxygen-induced disorder inhibiting function to food and drink, and method of producing food and drink having active oxygen-induced disorder inhibiting function added thereto 审中-公开
标题翻译：将活性氧诱导性疾病抑制功能添加到食物和饮料中的方法，以及生产具有活性氧诱导性疾病抑制功能的食物和饮料的方法
公开(公告)号：JP2014140373A
公开(公告)日：2014-08-07
申请号：JP2014058248
申请日：2014-03-20
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： MORIMITSU KOJIRO , KUBOTA KIKUE , HIRUMA MIHOKO
IPC分类号： A23L1/30 , A21D2/14 , A21D13/00 , A23G1/00 , A23G1/30 , A23G3/50 , A23G4/00 , A23G9/32 , A23G9/44 , A23G9/52 , A23L1/24 , A23L2/02 , A23L2/52 , A61K31/122 , A61K31/365 , A61K31/366 , A61P39/06
摘要： PROBLEM TO BE SOLVED: To provide an active oxygen-induced disorder inhibiting agent, and a method for adding an active oxygen-induced disorder inhibiting function to food and drink.SOLUTION: This invention relates to a method for adding at least one selected from cyclic carbonyl compounds represented by the formulae 1, 2 and 3 to food and drink.
摘要翻译：要解决的问题：提供活性氧诱导障碍抑制剂，以及向食品和饮料中添加活性氧诱导障碍抑制功能的方法。解决方案：本发明涉及一种添加至少一种选自环状由式1,2和3表示的羰基化合物用于食品和饮料。

6. 发明专利

JP2013082740A Platelet aggregation inhibitor 有权
标题翻译： PLATELET聚合抑制剂
公开(公告)号：JP2013082740A
公开(公告)日：2013-05-09
申请号：JP2013005464
申请日：2013-01-16
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： MORIMITSU KOJIRO , KUBOTA KIKUE , HIRUMA MIHOKO
IPC分类号： A61K31/341 , A61P7/02 , A61P9/00
摘要： PROBLEM TO BE SOLVED: To provide a novel platelet aggregation inhibitor capable of relieving or preventing various symptoms caused by aggregation of platelets, particularly, a platelet aggregation inhibitor available more conveniently and capable of being mass-produced easily.SOLUTION: The platelet aggregation inhibitor includes a compound represented by formula (1) as an active ingredient. There are further provided blood flow improving agents and antithrombotic agents each containing the platelet aggregation inhibitor as an active ingredient.
摘要翻译：解决问题的方法：提供一种能够缓解或预防血小板聚集引起的各种症状的新型血小板聚集抑制剂，特别是更方便且能够大规模生产的血小板聚集抑制剂。
解决方案：血小板聚集抑制剂包括由式（1）表示的化合物作为活性成分。另外提供各自含有血小板聚集抑制剂作为有效成分的血流量改善剂和抗血栓形成剂。版权所有（C）2013，JPO＆INPIT

7. 发明专利

JP2008013486A Arachidonate metabolism inhibitor 审中-公开
标题翻译： ARACHIDONATE代谢抑制剂
公开(公告)号：JP2008013486A
公开(公告)日：2008-01-24
申请号：JP2006186102
申请日：2006-07-05
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： HIRUMA MIHOKO , TAKAI EIJI , MORIMITSU KOJIRO , KUBOTA KIKUE
IPC分类号： A61K31/201 , A23L1/30 , A61K31/216 , A61P7/02 , A61P9/00 , A61P29/00 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a new arachidonate metabolism inhibitor reducing or preventing various symptoms caused by arachidonate dysbolism, and to provide the arachidonate metabolism inhibitor especially more simply available and easily achieving mass production.
SOLUTION: The problems can be solved by the arachidonate metabolism inhibitor comprising at least one selected from nonanoic acid, 2-decenoic acid, 4-decenoic acid, 9-decenoic acid and tiglic esters as an active ingredient. Furthermore, a blood flow improver, an antithrombotic agent, an anti-inflammatory agent or an anti-allergic agent comprising the arachidonate metabolism inhibitor as the active ingredient is provided.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种新的花生四烯酸代谢抑制剂，其减少或预防由花生四烯酸钠引起的各种症状，并且提供花生四烯酸代谢抑制剂，特别是更容易获得并容易实现批量生产。解决方案：所述问题可以通过花生四烯酸代谢抑制剂来解决，所述抑制剂包含选自壬酸，2-癸烯酸，4-癸烯酸，9-癸烯酸和tiglic酯中的至少一种作为活性成分。此外，提供了含有花生四烯酸代谢抑制剂作为活性成分的血流改善剂，抗血栓形成剂，抗炎剂或抗过敏剂。版权所有（C）2008，JPO＆INPIT

8. 发明专利

JP2009091261A Platelet aggregation inhibitor 有权
标题翻译： PLATELET聚合抑制剂
公开(公告)号：JP2009091261A
公开(公告)日：2009-04-30
申请号：JP2007260672
申请日：2007-10-04
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： MORIMITSU KOJIRO , KUBOTA KIKUE , HIRUMA MIHOKO
IPC分类号： A61K31/343 , A61K31/365 , A61K31/366 , A61K31/37 , A61P7/02
摘要： PROBLEM TO BE SOLVED: To provide a new platelet aggregation inhibitor relieving or preventing various symptoms caused by the platelet aggregation, and a bloodstream-improving agent and an antithrombotic agent by using the above inhibitor as an active ingredient. SOLUTION: This platelet aggregation inhibitor is provided by containing at least 1 compound selected from a group of compounds having oxygen-containing ring structures expressed by formulas (1) to (6) as an active ingredient, and the bloodstream-improving agent and antithrombotic agent containing the above compound as the active ingredient are also provided. As the platelet aggregation inhibitor, especially (R)-2-deceno-δ-lactone is preferable. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种新的血小板聚集抑制剂，通过使用上述抑制剂作为活性成分，缓解或预防血小板聚集引起的各种症状，血液改善剂和抗血栓形成剂。解决方案：该血小板聚集抑制剂通过含有至少1种选自具有由式（1）至（6）表示的含氧环结构的化合物的化合物作为活性成分的化合物，并且血液提高剂并且还提供含有上述化合物作为活性成分的抗血栓形成剂。作为血小板聚集抑制剂，优选（R）-2-癸烯-δ-内酯。版权所有（C）2009，JPO＆INPIT

9. 发明专利

JP2013082739A Platelet aggregation inhibitor 审中-公开
标题翻译： PLATELET聚合抑制剂
公开(公告)号：JP2013082739A
公开(公告)日：2013-05-09
申请号：JP2013005463
申请日：2013-01-16
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： MORIMITSU KOJIRO , KUBOTA KIKUE , HIRUMA MIHOKO
IPC分类号： A61K31/343 , A61K31/352 , A61P7/02 , A61P9/00
摘要： PROBLEM TO BE SOLVED: To provide a novel platelet aggregation inhibitor capable of relieving or preventing various symptoms caused by aggregation of platelets, particularly, a platelet aggregation inhibitor available more conveniently and capable of being mass-produced easily.SOLUTION: The platelet aggregation inhibitor includes at least one compound selected from the group consisting of compounds having oxygen-containing circular structures represented by formulas (1) to (3) as an active ingredient. There are further provided blood flow improving agents and antithrombotic agents each containing the platelet aggregation inhibitor as an active ingredient.

10. 发明专利

JP2013067658A Platelet aggregation inhibitor 有权
标题翻译： PLATELET聚合抑制剂
公开(公告)号：JP2013067658A
公开(公告)日：2013-04-18
申请号：JP2013002209
申请日：2013-01-10
申请人： Soda Aromatic Co Ltd , 曽田香料株式会社
发明人： HIRUMA MIHOKO , TAKAI EIJI , MORIMITSU KOJIRO , KUBOTA KIKUE
IPC分类号： A61K31/22 , A23L1/30 , A23L2/52 , A61K31/222 , A61P7/02
摘要： PROBLEM TO BE SOLVED: To provide a new platelet aggregation inhibitor which can reduce or prevent various symptoms caused by the aggregation of platelets, and particularly, to provide a platelet aggregation inhibitor which can be more easily obtained and whose mass production can be easily achieved as well.SOLUTION: The platelet aggregation inhibitor includes at least one selected from tiglate esters as an active constituent. Further, a flow blood improving agent or an antithrombotic agent using the platelet aggregation inhibitor as an active constituent is provided.

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