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    • 3. 发明专利
    • Platelet aggregation inhibitor
    • PLATELET聚合抑制剂
    • JP2009091261A
    • 2009-04-30
    • JP2007260672
    • 2007-10-04
    • Soda Aromatic Co Ltd曽田香料株式会社
    • MORIMITSU KOJIROKUBOTA KIKUEHIRUMA MIHOKO
    • A61K31/343A61K31/365A61K31/366A61K31/37A61P7/02
    • PROBLEM TO BE SOLVED: To provide a new platelet aggregation inhibitor relieving or preventing various symptoms caused by the platelet aggregation, and a bloodstream-improving agent and an antithrombotic agent by using the above inhibitor as an active ingredient. SOLUTION: This platelet aggregation inhibitor is provided by containing at least 1 compound selected from a group of compounds having oxygen-containing ring structures expressed by formulas (1) to (6) as an active ingredient, and the bloodstream-improving agent and antithrombotic agent containing the above compound as the active ingredient are also provided. As the platelet aggregation inhibitor, especially (R)-2-deceno-δ-lactone is preferable. COPYRIGHT: (C)2009,JPO&INPIT
    • 要解决的问题:提供一种新的血小板聚集抑制剂,通过使用上述抑制剂作为活性成分,缓解或预防血小板聚集引起的各种症状,血液改善剂和抗血栓形成剂。 解决方案:该血小板聚集抑制剂通过含有至少1种选自具有由式(1)至(6)表示的含氧环结构的化合物的化合物作为活性成分的化合物,并且血液提高剂 并且还提供含有上述化合物作为活性成分的抗血栓形成剂。 作为血小板聚集抑制剂,优选(R)-2-癸烯-δ-内酯。 版权所有(C)2009,JPO&INPIT
    • 5. 发明专利
    • Calcium antagonist
    • CALCIUM ANTAGONIST
    • JP2013064023A
    • 2013-04-11
    • JP2013006121
    • 2013-01-17
    • Soda Aromatic Co Ltd曽田香料株式会社
    • MORIMITSU KOJIROKUBOTA KIKUEHIRUMA MIHOKO
    • A61K31/341A61P9/06A61P9/10A61P9/12A61P25/08A61P43/00
    • PROBLEM TO BE SOLVED: To provide a novel calcium antagonist capable of reducing or preventing various adverse effects involving intracecullar calcium ion, particularly, a calcium antagonist which is more easily available and can easily attain mass production.SOLUTION: The calcium antagonist contains a compound represented by formula (1) (wherein R1 and R2 each independently represent a 1-3C linear alkyl, and R3 represents a 1-10C linear alkylidene) as an active ingredient. Further, an anti-arrhythmic agent, a vascular relaxant, a cerebral vascular antispasmodic, and the like each including the calcium antagonist as an active ingredient are provided.
    • 待解决的问题:提供能够减少或预防涉及脑内钙离子的各种副作用的新颖的钙拮抗剂,特别是更易于获得并可容易地达到批量生产的钙拮抗剂。 解决方案:钙拮抗剂含有式(1)表示的化合物(其中R 1和R 2各自独立地表示1-3个直链烷基,R 3表示1-10个碳原子的直链亚烷基)作为活性成分。 此外,提供了包含钙拮抗剂作为活性成分的抗心律变化剂,血管松弛剂,脑血管解痉药等。 版权所有(C)2013,JPO&INPIT
    • 8. 发明专利
    • Arachidonate metabolism inhibitor
    • ARACHIDONATE代谢抑制剂
    • JP2008013486A
    • 2008-01-24
    • JP2006186102
    • 2006-07-05
    • Soda Aromatic Co Ltd曽田香料株式会社
    • HIRUMA MIHOKOTAKAI EIJIMORIMITSU KOJIROKUBOTA KIKUE
    • A61K31/201A23L1/30A61K31/216A61P7/02A61P9/00A61P29/00A61P43/00
    • PROBLEM TO BE SOLVED: To provide a new arachidonate metabolism inhibitor reducing or preventing various symptoms caused by arachidonate dysbolism, and to provide the arachidonate metabolism inhibitor especially more simply available and easily achieving mass production.
      SOLUTION: The problems can be solved by the arachidonate metabolism inhibitor comprising at least one selected from nonanoic acid, 2-decenoic acid, 4-decenoic acid, 9-decenoic acid and tiglic esters as an active ingredient. Furthermore, a blood flow improver, an antithrombotic agent, an anti-inflammatory agent or an anti-allergic agent comprising the arachidonate metabolism inhibitor as the active ingredient is provided.
      COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:提供一种新的花生四烯酸代谢抑制剂,其减少或预防由花生四烯酸钠引起的各种症状,并且提供花生四烯酸代谢抑制剂,特别是更容易获得并容易实现批量生产。 解决方案:所述问题可以通过花生四烯酸代谢抑制剂来解决,所述抑制剂包含选自壬酸,2-癸烯酸,4-癸烯酸,9-癸烯酸和tiglic酯中的至少一种作为活性成分。 此外,提供了含有花生四烯酸代谢抑制剂作为活性成分的血流改善剂,抗血栓形成剂,抗炎剂或抗过敏剂。 版权所有(C)2008,JPO&INPIT
    • 9. 发明专利
    • Platelet aggregation inhibitor
    • PLATELET聚合抑制剂
    • JP2013082739A
    • 2013-05-09
    • JP2013005463
    • 2013-01-16
    • Soda Aromatic Co Ltd曽田香料株式会社
    • MORIMITSU KOJIROKUBOTA KIKUEHIRUMA MIHOKO
    • A61K31/343A61K31/352A61P7/02A61P9/00
    • PROBLEM TO BE SOLVED: To provide a novel platelet aggregation inhibitor capable of relieving or preventing various symptoms caused by aggregation of platelets, particularly, a platelet aggregation inhibitor available more conveniently and capable of being mass-produced easily.SOLUTION: The platelet aggregation inhibitor includes at least one compound selected from the group consisting of compounds having oxygen-containing circular structures represented by formulas (1) to (3) as an active ingredient. There are further provided blood flow improving agents and antithrombotic agents each containing the platelet aggregation inhibitor as an active ingredient.
    • 解决问题的方法:提供一种能够缓解或预防血小板聚集引起的各种症状的新型血小板聚集抑制剂,特别是更方便且能够大规模生产的血小板聚集抑制剂。 解决方案:血小板聚集抑制剂包括至少一种选自由式(1)至(3)表示的含氧环状结构的化合物作为有效成分的化合物。 另外提供各自含有血小板聚集抑制剂作为有效成分的血流量改善剂和抗血栓形成剂。 版权所有(C)2013,JPO&INPIT