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1. 发明专利

JP2012196301A Method for inspecting dialyzer in hemodialysis apparatus and hemodialysis apparatus 有权
标题翻译：检测血液透析仪和血液透析仪器中的DIALYZER的方法
公开(公告)号：JP2012196301A
公开(公告)日：2012-10-18
申请号：JP2011061989
申请日：2011-03-22
申请人： Nipro Corp , Shibuya Kogyo Co Ltd , ニプロ株式会社 , 澁谷工業株式会社
发明人： UEDA MITSUTAKA , SAWADA TOSHIHARU , NOZATO NOBUYUKI
IPC分类号： A61M1/14
摘要： PROBLEM TO BE SOLVED: To provide a method for inspecting a dialyzer in a hemodialysis apparatus and a hemodialysis apparatus, with which leakage from a filtration membrane in a dialyzer is detected while preventing the damage of a blood circuit or the filtration membrane.SOLUTION: The hemodialysis apparatus includes the dialyzer in which a dialysis fluid circuit for circulating a dialysis fluid and the blood circuit for circulating blood are connected to each other, and a pressure measuring unit for measuring the pressure in the dialysis fluid circuit. While the fluid is held in the dialysis fluid circuit and the blood circuit is opened to the atmosphere, the fluid in the dialysis fluid circuit is discharged to reduce the internal pressure of the dialysis fluid circuit to a negative pressure, and the pressure of the dialysis fluid circuit is measured by the pressure measuring unit. When the pressure in the dialysis fluid circuit does not have a variation, it is determined that the filtration membrane of the dialyzer does not have an abnormal condition, and when the pressure in the dialysis fluid circuit has a variation, it is determined that the filtration membrane of the dialyzer has leakage.
摘要翻译：要解决的问题：提供一种用于检查血液透析装置和血液透析装置中的透析器的方法，其中检测出透析器中的过滤膜的泄漏，同时防止血液回路或过滤膜的损伤。解决方案：血液透析设备包括透析器，其中用于使透析液循环的透析流体回路和用于循环血液的血液回路彼此连接;以及压力测量单元，用于测量透析流体回路中的压力。当流体保持在透析流体回路中并且血液回路向大气开放时，透析流体回路中的流体被排出以将透析流体回路的内部压力降低到负压，并且透析压力流体回路由压力测量单元测量。当透析流体回路中的压力不具有变化时，判定透析器的过滤膜不具有异常状态，并且当透析液回路的压力变化时，判定为过滤透析器的膜有渗漏。版权所有（C）2013，JPO＆INPIT

2. 发明专利

JP2014008143A Dialyzer 有权
标题翻译：透析器
公开(公告)号：JP2014008143A
公开(公告)日：2014-01-20
申请号：JP2012145861
申请日：2012-06-28
申请人： Shibuya Kogyo Co Ltd , 澁谷工業株式会社
发明人： NOZATO NOBUYUKI
IPC分类号： A61M1/14 , A61M1/10 , B01D61/28 , B01D61/30 , B01D61/32
摘要： PROBLEM TO BE SOLVED: To provide a dialyzer capable of suppressing an increase in an internal pressure of a liquid supply passage when actuating a supply/discharge pump.SOLUTION: A dialyzer 1 includes: first and second chambers 21 and 22 that are partitioned into supply chambers 21a and 22a, recovery chambers 21b and 22b, and variable volume chambers 21c and 22c respectively; and a silicone oil pump P3 (a supply/discharge pump) for feeding a liquid to between the variable volume chamber 22c and the variable volume chamber 22c. A liquid supply passage 23 has a second on-off valve V12 (a pressure release valve) for releasing the pressure in the liquid supply passage. One chamber supplies the dialyzer with a fresh dialysate solution and recovers the used dialysate solution and, while the supply/discharge pump feeds the liquid from the variable volume chamber of the one chamber to the variable volume chamber of the other chamber, the internal pressure of the other chamber which increases thereby is released by the second on-off valve. The dialyzer can suppress an increase in an internal pressure of the liquid supply passage during dehydration.
摘要翻译：要解决的问题：提供能够抑制在供给/排出泵致动时液体供应通道的内部压力增加的透析器。解决方案：透析器1包括：分隔成供给的第一和第二室21和22 室21a和22a，回收室21b和22b以及可变体积室21c和22c; 以及用于将液体供给到可变容积室22c和可变容积室22c之间的硅油泵P3（供给/排出泵）。液体供给通道23具有用于释放液体供应通道中的压力的第二开关阀V12（压力释放阀）。一个腔室向透析器供应新鲜的透析液，并回收使用过的透析液，而供应/排出泵将液体从一个腔室的可变体积腔室送入另一腔室的可变体积腔室时，内部压力由此增加的另一个室由第二开关阀释放。透析器可以抑制脱水期间液体供给通道的内部压力的增加。

3. 发明专利

JP2013013437A Hemodialyzer 有权
标题翻译： HEMODIALYZER
公开(公告)号：JP2013013437A
公开(公告)日：2013-01-24
申请号：JP2011146269
申请日：2011-06-30
申请人： Shibuya Kogyo Co Ltd , 澁谷工業株式会社
发明人： NOZATO NOBUYUKI
IPC分类号： A61M1/14
摘要： PROBLEM TO BE SOLVED: To permit a passage 27 for dialysis original fluid to be cleaned by a cleaning solution prepared at a prescribed concentration.SOLUTION: The hemodialyzer 1 includes a chamber having a supply chamber 21a supplying a fresh dialysis fluid to a dialyzer 2 and a recovery chamber 21b recovering a used dialysis fluid from the dialyzer 2, a water supply passage 25 supplying water to the supply chamber 21a of the chamber, the passage 27 for the dialysis original fluid connected with the water supply passage 25 and supplying the dialysis original fluid, and a passage 28 for an original cleaning solution supplying the original cleaning solution to the supply chamber 21a. A passage 52 for waste cleaning solution is provided in the passage 27 to discharge the cleaning solution discharged from the supply chamber 21a of the chamber to the passage 27. The cleaning solution is flowed in the opposite direction of the dialysis original fluid in the passage 27 and then discharged through the passage for the waste cleaning solution and the passage 27 is cleaned.
摘要翻译：要解决的问题：允许用通过预定浓度制备的清洁溶液清洁透析原液的通道27。解决方案：血液透析器1包括具有向透析器2供应新鲜透析流体的供给室21a和从透析器2回收使用的透析液的回收室21b的供给通道25，用于与供水通道25连接并提供透析原液的透析原液的通道27和用于将原始清洁溶液供应到供应室21a的原始清洁溶液的通道28。在通道27中设置有用于废液清洗液的通道52，以将从室的供应室21a排出的清洗溶液排出到通道27.清洗溶液沿通道27中透析原液的相反方向流动然后通过用于废物清洁溶液的通道排出，并且清洁通道27。版权所有（C）2013，JPO＆INPIT

4. 发明专利

JP2012170722A Hemodialyzer 审中-公开
标题翻译：血液透析
公开(公告)号：JP2012170722A
公开(公告)日：2012-09-10
申请号：JP2011036976
申请日：2011-02-23
申请人： Shibuya Kogyo Co Ltd , 澁谷工業株式会社
发明人： NOZATO NOBUYUKI
IPC分类号： A61M1/14 , A61M1/02
摘要： PROBLEM TO BE SOLVED: To discharge a liquid inside a dialysate circuit 4 from a liquid discharge port 32A, and to dry the inside of the dialysate circuit 4.SOLUTION: The dialysate circuit 4 includes an air supply passage 57 for introducing the air into a liquid supply passage 31, the air supply passage 57 is disposed with a solenoid on-off valve V105, and the liquid supply passage 31 close to a liquid supply port 31A is disposed with a solenoid on-off valve V103. After an end of dialysis treatment, in a state that the solenoid on-off valve V103 is closed and that the solenoid valve V105 is opened, an air pump 22 is operated, so that the air is introduced into the dialysate circuit 4 from the air supply passage 57, and ventilation is performed for a prescribed time.
摘要翻译：要解决的问题：从液体排出口32A排出透析液回路4内的液体，并干燥透析液回路4的内部。解决方案：透析液回路4包括供气通道57 为了将空气引入液体供给通道31中，供气通道57设置有电磁开关阀V105，并且靠近液体供给口31A的液体供给通道31配置有螺线管通断阀V103 。在透析处理结束后，在螺线管通断阀V103闭合并且电磁阀V105打开的状态下，运行空气泵22，从而空气从空气引入透析液回路4 供给通道57，并且进行规定时间的通风。版权所有（C）2012，JPO＆INPIT

5. 发明专利

JP2015051191A 血液透析装置有权
标题翻译： HEMODIALYZER
公开(公告)号：JP2015051191A
公开(公告)日：2015-03-19
申请号：JP2013186144
申请日：2013-09-09
申请人：澁谷工業株式会社 , Shibuya Kogyo Co Ltd
发明人： NOZATO NOBUYUKI
IPC分类号： A61M1/14 , A61M1/16 , B01D61/30 , B01D61/58 , B01D63/02 , B01D65/02 , B01D65/10 , G01N15/08
摘要：【解決手段】透析液供給通路24に接続されて他端が大気開放可能に設けられた大気開放通路(第3分岐通路43)を上記第1浄化フィルタ31の下流側に設ける。制御手段は、上記透析液供給通路から第1浄化フィルタの一次側31aへの液体の供給を停止するとともに上記大気開放通路を大気開放した状態で、第1分岐通路41を介して第1浄化フィルタの一次側から透析液回収通路に液体を回収させて、その際の透析液回収通路内の圧力を検出して第1浄化フィルタのリークチェックを行い、次に、上記透析液供給通路から上記第1浄化フィルタの一次側に液体を供給するとともに、上記第1分岐通路を介して浄化フィルタの一次側から透析液回収通路に液体を回収させて浄化フィルタのフラッシングを行う。【効果】浄化フィルタのリークチェックを行うとともに、浄化フィルタに捕捉された細菌やエンドトキシンを効率的に除去できる。【選択図】図3
摘要翻译：要解决的问题：有效地去除净化过滤器捕获的细菌或内毒素，同时检查净化过滤器的泄漏。解决方案：一个空气开放通道（第三分支通道43），其一端连接到透析液供应通道24，在第一净化过滤器31的下游侧设置有能够对空气开放的另一端。控制单元通过以下方式对第一净化过滤器进行泄漏检查：将流体从第一净化过滤器将第一净化过滤器的流体从第一净化过滤器的一次侧31a供给到空气开放通路的状态下，通过第一分支通路41进行透析液回收通道的第一净化过滤器，空气; 并在检索期间检测透析液回收通道中的压力。之后，控制装置通过将来自透析液供给通道的流体供给到第一净化过滤器的初级侧，使净化过滤器的初级侧的液体从透析液回收通道通过第一个分支通道。

6. 发明专利

JP2012191992A Hemodialysis device 有权
标题翻译： HEMODIALYSIS DEVICE
公开(公告)号：JP2012191992A
公开(公告)日：2012-10-11
申请号：JP2011056611
申请日：2011-03-15
申请人： Shibuya Kogyo Co Ltd , 澁谷工業株式会社
发明人： NOZATO NOBUYUKI
IPC分类号： A61M1/14
CPC分类号： A61M1/16 , A61M1/1601 , A61M1/1672 , A61M1/1692 , A61M2205/15 , A61M2205/18 , A61M2205/3331 , A61M2205/705 , A61M2205/707
摘要： PROBLEM TO BE SOLVED: To provide a dialysate filter in which leak check of the dialysate filter can be quickly and precisely done.SOLUTION: A hemodialysis device 1 is provided with a dialysate filter, and is provided with a testing passage for discharging fluid from one of a space on the inflow side of the dialysate filter and a space on the discharge side of the dialysate filter, an opening means 42 for opening the other space to the atmosphere, a pressure detection means for detecting a pressure variation in the one space, and an assessing means 54 for assessing the quality of the dialysate filter on the basis of the pressure variation. A control means causes the dialysate to be discharged from the one space by a dialysate pump 52 via the testing passage, and causes the other space to be opened to the atmosphere by the opening means 42, and when the one space is depressurized to a first negative pressure, the one space is depressurized to a second negative pressure by a draining means. The assessing means assesses that the dialysate filter is good when the pressure detection means does not detect a pressure variation from the second negative pressure, and the assessing means assesses that the dialysate filter is bad when the pressure detection means detects a pressure variation.
摘要翻译：要解决的问题：提供透析液过滤器，其中可以快速和精确地完成透析液过滤器的泄漏检查。解决方案：血液透析装置1设置有透析过滤器，并且设置有用于从透析液过滤器的流入侧的空间中的一个排出流体的测试通道和透析液过滤器的排出侧的空间，用于将另一空间打开到大气的打开装置42，用于检测一个空间中的压力变化的压力检测装置，以及用于基于压力变化来评估透析液过滤器的质量的评估装置54。控制装置使得透析液经由测试通道由透析泵52从一个空间排出，并且通过打开装置42使另一空间向大气打开，并且当一个空间被减压到第一负压，通过排水装置将一个空间减压至第二负压。评估装置评估当压力检测装置没有检测到来自第二负压的压力变化时透析液过滤器良好，并且当压力检测装置检测到压力变化时，评估装置评估透析过滤器是不好的。版权所有（C）2013，JPO＆INPIT

7. 发明专利

JP2007296119A Pressure measurement apparatus and method of blood circuit 审中-公开
标题翻译：压力测量装置及血液循环方法
公开(公告)号：JP2007296119A
公开(公告)日：2007-11-15
申请号：JP2006126709
申请日：2006-04-28
申请人： Nipro Corp , Shibuya Kogyo Co Ltd , ニプロ株式会社 , 澁谷工業株式会社
发明人： SHIOYAMA TADAO , SAWADA TOSHIHARU , NOZATO NOBUYUKI
IPC分类号： A61M1/14
摘要： PROBLEM TO BE SOLVED: To provide a pressure measurement apparatus of a blood circuit which measures the pressure of blood passing through an air trap chamber and, at the same time, eliminates the need for holding air within the air trap chamber, and also to provide a measurement method for improving measurement precision.
SOLUTION: The blood circuit 3 of a hemodialysis apparatus 1 has the air trap chamber 13 having a cylindrical unit 15 made of a soft material. The cylindrical unit 15 has a pressure measurement apparatus 14 for measuring the pressure of the blood passing through the cylindrical unit. When a pressure receiving member 32 receives pressing force via movement of the surface of the cylindrical unit, the pressing force is detected by a strain gauge 33 composing a detection means 22 and the pressing force detected by the strain gauge 33 is converted into a measurement value of the inner pressure. A comparison means 5a compares, at predetermined intervals, the measurement value measured by the pressure measurement apparatus and a measurement value of the pressure of dialysis liquid measured by a liquid pressure measurement apparatus 42 installed within a liquid circuit 4 and cancels a measurement error by correcting the converted value acquired by converting the pressing force detected by the strain gauge.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种血液回路的压力测量装置，其测量通过空气阱室的血液的压力，并且同时消除了在空气阱室内保持空气的需要，以及还提供了提高测量精度的测量方法。解决方案：血液透析装置1的血液回路3具有由软质材料构成的圆筒部15的吸气室13。圆柱形单元15具有用于测量通过圆筒形单元的血液的压力的压力测量装置14。当压力接收构件32通过圆筒形单元的表面的移动接收按压力时，通过构成检测装置22的应变仪33检测按压力，并且将由应变仪33检测的按压力转换成测量值的内压。比较装置5a以预定的间隔比较由压力测量装置测量的测量值和通过安装在液体回路4内的液体压力测量装置42测量的透析液的压力的测量值，并通过校正来消除测量误差通过转换由应变计检测的按压力而获得的转换值。版权所有（C）2008，JPO＆INPIT

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