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1. 发明专利

JP2000245493A PREPARATION OF POLYAMINE COMPOSITION 失效
公开(公告)号：JP2000245493A
公开(公告)日：2000-09-12
申请号：JP5683399
申请日：1999-03-04
申请人： SNOW BRAND MILK PROD CO LTD
发明人： TANIMOTO YOSHIHIRO , YAKABE TAKASHI , NAKANO HIROSHI , SHIMATANI MASAHARU
IPC分类号： C07C209/62 , C07C211/09 , C07C211/14 , C12P13/00
摘要： PROBLEM TO BE SOLVED: To effectively obtain a polyamine composition in high yield in an industrial scale having various bioactivity useful for medicine or the like by collecting polyamine from digesting the content of yeast with nuclease or hydrolyzing with alkali. SOLUTION: The subject polyamine composition comprising spermidine, spermine or the like useful for nourishment composition, gastrin releasing inhibitor composition for intake, immunoactivable agents or the like, is obtained effectively in high yield and in an industrial scale by inoculating the yeast in a culturing medium, culturing at 30 deg.C for 48 hours under ventilation and agitation, collecting the culture fungus by a centrifugal separation of cultured solution, extracting the content of the yeast under the condition of 4.8% NaCl concentration, pH 6.0, at 95 deg.C for 3.5 hours, digesting the extract with a nuclease included in the content of the yeast or the like or hydrolyzing with alkali, adsorbing the polyamine by passing the extract through a column packed with a cation-exchanging resin, washing the column, eluting and collecting the polyamine.

2. 发明专利

JPH04320650A HYDROLYZED-MILK PEPTIDE EXCELLENT IN EMULSIFYING PROPERTIES AND LOW IN ALLERGIC PROPERTIES 失效
公开(公告)号：JPH04320650A
公开(公告)日：1992-11-11
申请号：JP11407891
申请日：1991-04-18
申请人： SNOW BRAND MILK PROD CO LTD
发明人： TAKAHASHI NOBUAKI , SHIMATANI MASAHARU , SADO HIDEKI , IDOTA TADASHI
IPC分类号： A23J3/08 , A23J3/34 , A23L1/305 , B01F17/30 , C07K14/435 , C07K14/47 , C07K14/76 , C12N9/50 , C12P21/06
摘要： PURPOSE:To provide the subject hydrolyzed-milk peptide excellent in emulsifying properties and low in allergenic properties. CONSTITUTION:A peptide obtained by hydrolyzing a milk serum protein in which the content of alpha-lactoalbumin is reduced to about 0.01-12wt.% based on its crude proteins using a protease and production thereof. The resultant peptide can be utilized as an intestinal nutritive agent, a powder milk or a protein source of other nutritive foods, can promote emulsification of the above- mentioned products and can reduce crisis of allergic reactions.

3. 发明专利

JPH04234960A CALCIUM ENRICHED FOOD AND PRODUCTION THEREOF 失效
公开(公告)号：JPH04234960A
公开(公告)日：1992-08-24
申请号：JP41530190
申请日：1990-12-27
申请人： SNOW BRAND MILK PROD CO LTD
发明人： OYOSHI SHIN , SHIMATANI MASAHARU , MATSUOKA YASUHIRO , ISHIYAMA YUMIKO
IPC分类号： A23C9/156 , A23L1/304 , A23L2/52 , A23L21/10
摘要： PURPOSE:To obtain the title food having excellent utility efficiency by blending a solution of a hydroxy acid which is reacted with a slightly water-soluble Ca salt, etc., and produces a slightly water-soluble Ca salt of hydroxy acid with the Ca salt in a range not to form the Ca salt of hydroxy acid, evolving a carbon dioxide gas and blending the solution with a food. CONSTITUTION:A solution of a hydroxy acid such as citric acid or tartaric acid which is reacted with a slightly water-soluble or water-insoluble Ca salt, etc., and produces a slightly water-soluble or water-insoluble Ca salt of hydroxy acid is blended with the Ca salt in a range not to form the Ca salt of hydroxy acid and a carbon dioxide is evolved to give a solution of the Ca salt of hydroxy acid. The solution is adjusted to pH 6-9 with an alkalizing agent and mixed with a food in a fluidized state to give the objective food.

4. 发明专利

JPH0349648A CHILDCARE POWDERED MILK HAVING NEUTRALIZING ABILITY OF BACTERIAL TOXIN 失效
公开(公告)号：JPH0349648A
公开(公告)日：1991-03-04
申请号：JP18414089
申请日：1989-07-17
申请人： SNOW BRAND MILK PROD CO LTD
发明人： SHIMATANI MASAHARU , SUGAWARA MAKIHIRO , KAWASAKI NORIHIRO , MURAKAMI YUJI , DOSEMARI SHUNICHI , IDOTA TADASHI
IPC分类号： A23C9/152
摘要： PURPOSE:To obtain a childcare powdered milk having a neutralizing ability of bacterial toxin by blending the childcare powdered milk with a sialic acid-bonded peptide or sialic acid-bonded oligosaccharide. CONSTITUTION:Childcare powdered milk blended with a sialic acid-bonded peptide and/or a sialic acid-bonded oligosaccharide. Sialic acid-bonded peptide prepared by treating a sialic acid bonded-protein derived from protein such as cow's milk with protease is preferable as the sialic acid-bonded peptide. Sialyllactose in a sialic acid- bonded oligosaccharide is contained in milk in a large amount and especially preferable with respect to the above-mentioned aim. The amount of the sialic acid-bonded peptide or sialic acid-bonded oligosaccharide based on the childcare powdered milk is >=3mg wt.% in the case of sialic acid-bonded peptide alone and >=3 mg wt.% also in the case of sialic acid-bonded oligosaccharide alone in terms of supplying a neutralizing ability of bacterial toxin similar to mother's milk. When childcare powdered milk is blended with both sialic acid-bonded peptide and sialic acid-bonded oligosaccharide, the blending ratio and the amounts of both the components are preferably determined by taking the neutralizing ability of bacterial toxin of the components into account.

5. 发明专利

JPH04330100A PRODUCTION OF KAPPA-CASEIN GLYCOMACROPEPTIDE 失效
公开(公告)号：JPH04330100A
公开(公告)日：1992-11-18
申请号：JP1911291
申请日：1991-01-21
申请人： SNOW BRAND MILK PROD CO LTD
发明人： KAWASAKI ISAHIRO , DOSEMARI SHUNICHI , SHIMATANI MASAHARU , IDOTA TADASHI
IPC分类号： A23J1/20 , A61K31/00 , A61K38/00 , A61K38/17 , A61P1/00 , A61P1/02 , A61P31/00 , A61P31/04 , C07K1/18 , C07K1/34 , C07K14/00 , C07K14/47
摘要： PURPOSE:To readily produce a kappa-casein glycomacropeptide having various bioactivities by adsorbing kappa-casein glycomacropeptide on an anion exchanger and isolating it from other mingled proteins. CONSTITUTION:A milky raw material containing kappa-casein glycomacropeptide with

6. 发明专利

JPH04316450A PRODUCTION OF COMPOSITION CONTAINING SIALIC ACID 失效
公开(公告)号：JPH04316450A
公开(公告)日：1992-11-06
申请号：JP1911391
申请日：1991-01-21
申请人： SNOW BRAND MILK PROD CO LTD
发明人： SHIMATANI MASAHARU , UCHIDA YUKIO , MATSUNO ICHIRO , OYOSHI SHIN , ISHIYAMA YUMIKO
IPC分类号： A23C9/142 , A23C9/146 , A23C21/00 , C07H3/06 , C07H15/10
摘要： PURPOSE:To simply and efficiently produce the subject composition useful as a raw material for foods, etc., at a low cost in an industrial scale by adjusting a milk whey containing a sialic acid to a prescribed acidic pH range and subsequently bringing the adjusted milk whey into contact with a cation exchange material. CONSTITUTION:A milk whey containing a sialic acid is adjusted to a pH of 2-5 and subsequently brought into contact with a cation exchange material to provide the objective composition. The composition is preferably concentrated, subjected to the removal of lactose by a crystallization method and subsequently dried into the powder of the composition.

7. 发明专利

JPH034742A PREPARATION OF DESALTED MILK 失效
公开(公告)号：JPH034742A
公开(公告)日：1991-01-10
申请号：JP13950789
申请日：1989-06-01
申请人： SNOW BRAND MILK PROD CO LTD
发明人： SHIMATANI MASAHARU , SHIGEMATSU AKINORI , HIRAOKA YASUNOBU , MURAKAMI YUJI , IDOTA TADASHI
IPC分类号： A23C9/144 , A23C9/146 , A23C9/18 , A23C21/00
摘要： PURPOSE:To easily and surely obtain the objective desalted milk for confectionery, etc., having a low ash content and a specific pH by adding a milk having a specific pH to a milk treated by electrodialysis and cation exchange resin treatment and treating the adjusted milk with an anion exchange resin. CONSTITUTION:(A) A raw milk treated by electrodialysis and cation exchange resin treatment (e.g. milk composed of one or more components selected from whole fat milk, whey, permeate, lactose mother liquor, defatted milk and butter milk) is mixed with (B) a milk subjected only to electrodialysis to effect the desalting treatment of a part of ash and having a pH of 6.0-7.0 and the obtained pH-adjusted milk is subjected to anion exchange resin treatment to obtain the objective desalted milk. If necessary, the desalted milk is concentrated and dried to powder.

8. 发明专利

JP2009082145A Method for producing polyamine composition 有权
标题翻译：生产聚氨酯组合物的方法
公开(公告)号：JP2009082145A
公开(公告)日：2009-04-23
申请号：JP2008320774
申请日：2008-12-17
申请人： Snow Brand Milk Prod Co Ltd , 雪印乳業株式会社
发明人： TANIMOTO YOSHIHIRO , YAKABE TAKASHI , NAKANO HIROSHI , SHIMATANI MASAHARU
IPC分类号： A23L1/28 , C12P13/00
摘要： PROBLEM TO BE SOLVED: To provide a method for effectively producing a large amount of polyamine compositions at a high recovery from yeast fungus body contents. SOLUTION: This method for producing the polyamine composition through collecting polyamine includes: hydrolysing with alkali, Candidautilis and yeast fungus body contents such as Candidautilis; passing the product into a column in which positive ion exchange resin is filled to stick polyamine to the positive ion exchange resin; passing salt water into the column to elute stuck polyamine by hydrochloric acid; neutralizing the product followed by desalting by electrodialysis, and freeze-drying the product. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：提供一种从酵母真菌体内含量高回收率有效生产大量多胺组合物的方法。解决方案：通过收集多胺制备多胺组合物的方法包括：用碱水解，Candidautilis和酵母菌体内容物如Candidautilis; 将产物送入其中填充正离子交换树脂以将多胺粘附到正离子交换树脂的柱中; 将盐水通入盐水中，用盐酸洗脱多胺; 中和产物，然后通过电渗析脱盐，并冷冻干燥产物。版权所有（C）2009，JPO＆INPIT

9. 发明专利

JP2001008663A PRODUCTION OF POLYAMINE-CONTAINING COMPOSITION 失效
公开(公告)号：JP2001008663A
公开(公告)日：2001-01-16
申请号：JP18463799
申请日：1999-06-30
申请人： SNOW BRAND MILK PROD CO LTD
发明人： TANIMOTO YOSHIHIRO , YAKABE TAKASHI , SHIMATANI MASAHARU , SHIGEMATSU AKINORI , TOMIZAWA AKIRA
IPC分类号： A23C9/142 , A23L1/30
摘要： PROBLEM TO BE SOLVED: To obtain the subject composition good in flavor, rich in spermidine and spermine and useful as a food material or the like by isolating and collecting polyamines from a permeate obtained by ultrafiltration membrane treatment at a specific pH of a milk or milk material. SOLUTION: This composition good in flavor, rich in spermidine and spermine, and extremely highly useful as a food material or the like is obtained at low cost by isolating and collecting polyamines, by at least one means among ion exchange method, membrane fractionation and electrodialysis, from a permeate obtained by adding an inorganic acid such as sulfuric, hydrochloric acetic or phosphoric acid, organic acid such as lactic or citric acid, and/or microorganisms viable through assimilating lactoingredients and capable of forming organic acids (e.g. lactic acid bacteria, propionic acid bacteria, Bacillus bifidus) to a milk or milk material to lower its pH to

10. 发明专利

JP2000204067A L-CARNITINE PREPARATION 失效
公开(公告)号：JP2000204067A
公开(公告)日：2000-07-25
申请号：JP672999
申请日：1999-01-13
申请人： SNOW BRAND MILK PROD CO LTD
发明人： YAKABE TAKASHI , TAKAMICHI KIYOKO , SHIMATANI MASAHARU , IDOTA TADASHI
IPC分类号： C07C227/40 , A23C9/142 , A23C9/144 , A23C9/146 , A23C9/20 , C07C227/28 , C07C229/22
摘要： PROBLEM TO BE SOLVED: To obtain a safe preparation easy to handle, useful as a medicament or food/drink, using a mammalian milk or milk preparation as raw material by including each specified amount of L-carnitine and lactose reducing ash content. SOLUTION: This preparation is obtained by including 0.1-100 mmol/1.00 g of L-carnitine, 20-95 g/100 g of lactose and

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