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1. 发明专利

JP2010019861A Skin substitutive membrane, metal mold, and method of manufacturing skin substitutive membrane, and method of evaluating agent for external application onto skin 有权
标题翻译：皮肤取代膜，金属模具和制造皮肤取代膜的方法以及用于外用于皮肤的评估剂的方法
公开(公告)号：JP2010019861A
公开(公告)日：2010-01-28
申请号：JP2009245952
申请日：2009-10-26
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： MIURA YOSHIMASA , MIZUNO HIROKO , HATAO MASATO , OGURI MOTOKI , HARA YUSUKE
IPC分类号： G01N33/50 , G01N21/33 , G01N33/15
CPC分类号： G01N33/5082
摘要： PROBLEM TO BE SOLVED: To provide a skin substitutive membrane capable of precisely measuring transparency and/or reflection characteristics of external application agent for the skin for ultraviolet rays, metal mold to be used for manufacturing the skin substitutive membrane, method of manufacturing the skin substitutive membrane, and a method of evaluating a skin medicine for external application using the skin substitutive membrane.
SOLUTION: The skin substitutive membrane of poly(methylmethacrylate), polyethylene, or nylon, the thickness of which is ≥0.1 mm to ≤5 mm, and the spectro-transparency is ≥50% to ≤100%, for the wavelength of ≥290 nm to ≤400 nm, wherein the surface is provided with a roughness due to being chamfered, the arithmetic mean roughness Sa is ≥13 μm to ≤30 μm.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供能够精确测量紫外线皮肤外用剂的透明性和/或反射特性的皮肤替代膜，用于制造皮肤替代膜的金属模，制造方法皮肤替代膜，以及使用皮肤替代膜评价外用皮肤药物的方法。
解决方案：聚（甲基丙烯酸甲酯），聚乙烯或尼龙的皮肤代用膜的厚度≥0.1mm至≤5mm，分光透明度≥50％至≤100％，波长 ≥290nm〜≤400nm，其中由于倒角而使表面具有粗糙度，算术平均粗糙度Sa为≥13μm〜≤30μm。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2006151831A Antioxidant, dna damage inhibitor or skin care preparation 审中-公开
标题翻译：抗氧化剂，DNA损伤抑制剂或皮肤护理制剂
公开(公告)号：JP2006151831A
公开(公告)日：2006-06-15
申请号：JP2004341247
申请日：2004-11-25
申请人： Kitasato Gakuen , Shiseido Co Ltd , 学校法人北里学園 , 株式会社資生堂
发明人： WATANABE TAKASHI , YOSHIKAWA TAKAFUMI , KUSAKARI TAKESHI , YOKOYAMA MINEYUKI , KOBAYASHI KOJI , OCHIAI NOBUHIKO , HATAO MASATO
IPC分类号： A61K8/00 , A61K8/96 , A61K36/18 , A61P17/16 , A61P39/06 , A61P43/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide an antioxidant and a DNA damage inhibitor having excellent free radical scavenging property, containing a vegetable extract as an active component and having high safety and provide a skin care preparation compounded with the agent. SOLUTION: The invention provides an antioxidant and a DNA damage inhibitor containing the extract of the flower of a plant of the genus Gentiana or the extract of Gentiana davidii or Gentiana urnula belonging to the genus Gentiana and a skin care preparation such as cosmetic containing the agent. The skin care preparation such as cosmetic compounded with the extract exhibits effectiveness to prevent the oxidation of skin lipid component, suppress the oxidative damage of the skin, the DNA damage and the aging of the skin and protects the skin. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：解决问题：提供具有优异的自由基清除性的抗氧化剂和DNA损伤抑制剂，其含有作为活性成分的植物提取物并具有高安全性，并提供与该药剂混合的护肤制剂。解决方案：本发明提供一种抗氧化剂和DNA损伤抑制剂，其含有龙胆龙属植物的花提取物或属于龙胆草属的龙胆草或龙胆草的提取物和护肤品如化妆品包含代理。与提取物复合的化妆品等护肤品，具有防止皮肤脂质成分氧化，抑制皮肤氧化损伤，DNA损伤及皮肤老化等作用的保护作用。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2005298441A Skin care preparation for bleaching 审中-公开
标题翻译：皮肤护理准备漂白
公开(公告)号：JP2005298441A
公开(公告)日：2005-10-27
申请号：JP2004120121
申请日：2004-04-15
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： OCHIAI NOBUHIKO , YAGI EIICHIRO , AITSU YOKO , UMISHIO KENICHI , HATAO MASATO
IPC分类号： A61K8/96 , A61K8/00 , A61K8/97 , A61Q1/00 , A61Q1/12 , A61Q19/00 , A61Q19/02 , A61K7/00 , A61K7/48
摘要： PROBLEM TO BE SOLVED: To obtain a skin care preparation for bleaching that controls melanogenesis, prevents and ameliorates pigmentation after suntan, stains, freckles, liver spots, etc., by including a plant extract having high safety as a bleaching agent.
SOLUTION: The skin care preparation for bleaching comprises an extract of Commiphora abyssinica of the genes Commiphora of family Burseraceae. The skin care preparation for bleaching comprises an extract of Cautleya spicata of the genus Cautleya of the family Cannaceae.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：通过包括具有高安全性的植物提取物作为漂白剂，获得控制黑色素生成的漂白护肤品，防止和改善晒黑，斑点，雀斑，肝斑等后的色素沉着。解决方案：用于漂白的皮肤护理制剂包括枸杞科的Commiphora基因的提取物。用于漂白的皮肤护理制剂包括蒿科科学家的Cautleya属的Cautleya spicata的提取物。版权所有（C）2006，JPO＆NCIPI

4. 发明专利

JPH11106346A IMMUNOACTIVATOR 失效
公开(公告)号：JPH11106346A
公开(公告)日：1999-04-20
申请号：JP9247498
申请日：1998-03-20
申请人： SHISEIDO CO LTD
发明人： YAGI EIICHIRO , IWAI ICHIRO , WADA MOTOTSUGU , HATAO MASATO , YAMAGUCHI KENJI , NAGANUMA MASAKO
IPC分类号： A61K8/96 , A61K8/00 , A61K8/97 , A61Q1/00 , A61Q1/12 , A61Q17/00 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To obtain the subject medicine, having activities capable of improving and preventing the decrease of immunoactivating activities and immunological function and capable of being daily used by allowing the medicine to include an Eugenia caryophyllata extract. SOLUTION: This medicine includes an Eugenia caryophyllata extract. The Eugenia caryophyllata extract is the extract of Eugenia caryophyllata, which is a plant of the family Myrtaceae, with water or an organic solvent, and obtained, for example, by stirring and extracting a dry powder of a bud, a leaf, a seed, an aboveground part or the entire plant of the Eugenia caryophyllata, or a cut material of the non-dry bud of Eugenia caryophyllata, with the water, methanol or the like for 1-10 hr under heating to 30-700 deg.C, and filtering the extract, and carrying out concentration, etc., of the filtrate. The formulating amount of the Eugenia caryophyllata extract is preferably 0.0005-10.0 wt.% as a dried material in the whole amount of the medicine. As a result, the objective medicine usable as a form of the skin preparation for external use having immunoactivating activities of the Eugenia caryophyllata extract, or improvement and prevention activities for the decrease of immunological function by ultraviolet rays is provided.

5. 发明专利

JPH02298338A EMULSION COMPOSITION 失效
公开(公告)号：JPH02298338A
公开(公告)日：1990-12-10
申请号：JP11627889
申请日：1989-05-10
申请人： SHISEIDO CO LTD
发明人： YONEYAMA TOSHIO , TANAKA TOSHIHIRO , SAITO TSUTOMU , HATAO MASATO , NANBA TOMIYUKI
IPC分类号： A61K8/55 , A61K8/06 , A61K8/34 , A61K8/58 , A61K8/72 , A61K8/89 , A61K9/107 , A61Q1/00 , A61Q1/12 , B01F17/54 , B01J13/00 , C08L83/08
摘要： PURPOSE:To improve resistance to water, perspiration and sebum by preparing an emulsion composition by mixing an outer phase contg. fluorine modified silicone compound, an inner phase contg. water or alcohol and a lipophilic surfactant. CONSTITUTION:An emulsion composition is prepd by mixing an outer phase (component A) contg. at least one kind of fluorine modified silicone compounds shown by the formula I (wherein (n) and (m)are the average of 1-150 and 0-150, respectively, (a) is an integer of 0-5 and Rf represents 1-8C perphloroalkyl group) an inner phase (component B) contg. water and/or alcohol and lipophilic surfactant (component C). The above mixture is made, preferably with the ratio of the components A to B ranging from 5:1 to 1:5 and with the component C added thereto in an amt. of 0.5-20wt.% (per emulsion composition). As a suitable example for the component C, 14-22C sorbitam monofatty acid ester is available.

6. 发明专利

JPH01242512A COSMETIC 失效
公开(公告)号：JPH01242512A
公开(公告)日：1989-09-27
申请号：JP6981888
申请日：1988-03-25
申请人： SHISEIDO CO LTD
发明人： HACHIMAN YOSHIO , YOKOYAMA HIROYUKI , HATAO MASATO
IPC分类号： A61K8/72 , A61K8/00 , A61K8/81 , A61K8/89 , A61Q1/00 , A61Q1/02
摘要： PURPOSE:To obtain a cosmetic preventing color darkening of existing cosmetic with time by using the cosmetic with existing one, raising water resistance, oil resistance and preventing function of secondary adhesion, capable of improving durability of makeup, by blending a cosmetic with a resin dissolved in a volatile solvent. CONSTITUTION:An overcoat cosmetic or cosmetic foundation is blended with a resin such as fluororesin, silicone resin, aromatic hydrocarbon resin, terpene resin. polybutene, polyisoprene, alkyd resin or PVA modified polymer, preferably silicone resin or fluororesin dissolved in a volatile solvent in the ratio of preferably 0.001-50wt.% resin and 1-99.999wt.% solvent to give a cosmetic capable of providing the above-mentioned effects by using the cosmetic especially after application of a make-up cosmetic or sun screening cosmetic or as a cosmetic foundation.

7. 发明专利

JPS63196505A MAKE-UP COSMETIC 失效
公开(公告)号：JPS63196505A
公开(公告)日：1988-08-15
申请号：JP2768787
申请日：1987-02-09
申请人： SHISEIDO CO LTD
发明人： TANAKA TOSHIHIRO , KUMAGAI SHIGENORI , HATAO MASATO
IPC分类号： A61K8/11 , A61K8/00 , A61K8/92 , A61Q1/00 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q1/12
摘要： PURPOSE:To obtain a make-up cosmetic capable of controlling applied color by degree of force in coating the skin with the cosmetic or by number of times of embrocations, by blending a cosmetic with a non-rigid resin capsule collapsing by compression, containing a colored component and an oil component as inner contents. CONSTITUTION:A cosmetic is blended with a non-rigid resin capsule collapsing by compression, containing a colored component selected from colored pigment, colored pearly luster pigment and oil-soluble dye and an oil component as inner contents, comprising a resin insoluble in the inner contents as a shell, having 10-50kg/cm compression (breaking) strength. The amount of the inner contents is 10-95wt., preferably 50-95wt.% based on sum of the capsule and the amount of the oil component is 40-99.9wt.%, preferably 60-99.5wt.% based on sum of the inner contents. The capsule has 1-100mum particle diameter and the about of the capsule is 5-50wt.% based on sum of the cosmetic.

8. 发明专利

JPS62246507A MAKE-UP COSMETIC 失效
公开(公告)号：JPS62246507A
公开(公告)日：1987-10-27
申请号：JP8901386
申请日：1986-04-17
申请人： SHISEIDO CO LTD
发明人： HATAO MASATO , TANAKA TOSHIHIRO , TAKADA SUSUMU
IPC分类号： A61K8/00 , A61K8/89 , A61K8/891 , A61K8/92 , A61Q1/00 , A61Q1/02 , A61Q1/10 , A61Q1/12 , C08L83/04
摘要： PURPOSE:To obtain a make-up cosmetic having excellent spreadability on the skin to give moist feeling and durable make-up, by compounding a specific amount of a silicone-treated powder and a specific amount of a mixed oil containing a specific amount of a silicone oil to a cosmetic base. CONSTITUTION:A make-up cosmetic, especially a powdery base composed mainly of powder and an oil is compression-molded in an inner dish to obtain a solid powdery cosmetic. As an alternative, an oily cosmetic powder is produced by melting a cosmetic base containing somewhat larger amount of oil component than the above solid cosmetic, pouring the molten base in an inner dish and cooling the product. The objective cosmetic having the above-mentioned effects can be prepared by compounding the above solid cosmetic powder or oily cosmetic powder with (A) one or more kinds of silicone-treated powder and (B) a mixed oil containing a silicon oil accounting for 50-100wt%, preferably >=70wt% of the whole oil component. The amount of the component A is 30-99wt%, preferably 50-92wt% and that of the component B is 1-70wt%.

9. 发明专利

JP2012063323A Evaluation method, evaluation device, and evaluation program for ultraviolet light prevention effect, and recording medium with the recorded program 有权
标题翻译：评估方法，评估装置和用于超紫外线防护效果的评估程序和记录的程序记录介质
公开(公告)号：JP2012063323A
公开(公告)日：2012-03-29
申请号：JP2010209818
申请日：2010-09-17
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： MIURA YOSHIMASA , HATAO MASATO
IPC分类号： G01N21/33
CPC分类号： G01N21/59 , G01N17/004 , G01N21/33
摘要： PROBLEM TO BE SOLVED: To achieve high-precision evaluation of prevention effect on ultraviolet light included in an irradiating sunlight source under use conditions of actual life in use environment.SOLUTION: The evaluation method of evaluating the ultraviolet light prevention effect on a measurement sample with which a member to be coated is coated includes a first step of measuring secular change in spectral transmission spectrum of the measurement sample at predetermined intervals in a predetermined wavelength region through light irradiation with the light source including ultraviolet rays, visible light rays, and infrared rays under preset light irradiation conditions; a second step of setting correlation between an irradiation time and an erythema effect amount per predetermined time, which is obtained by dividing an erythema effect amount of the measurement sample by an erythema effect amount per 1 MED, based upon the secular change in spectral transmission spectrum; and a third step of calculating an in vitro rSPF predicted value of the measurement sample with the time until when a time-integrated cumulative erythema effect amount reaches 1 MED from the correlation.
摘要翻译：要解决的问题：为了在使用环境中的使用寿命的使用条件下，对包含在照射太阳光源中的紫外线的防止效果进行高精度评价。＆lt; P＆gt;解决方案：评估涂覆有被涂覆部件的测量样品的紫外线防止效果的评估方法包括：以预定间隔以预定的方式测量测量样品的光谱透射光谱的长期变化的第一步骤通过在预设的光照射条件下通过光源照射包括紫外线，可见光线和红外线的波长区域; 基于频谱透射光谱的长期变化，设定照射时间与每预定时间的红斑效果量之间的相关性的第二步骤，其通过将测量样品的红斑效应量除以每1 MED的红斑效应量而获得 ; 以及计算测定样品的体外rSPF预测值的时间，直到时间积分累积红斑效应量从相关性达到1 MED的时间的第3步骤。版权所有（C）2012，JPO＆INPIT

10. 发明专利

JP2010107522A Skin-substitutive membrane, mold, method of manufacturing skin-substitutive membrane, and method of evaluating agent for external application onto skin 有权
标题翻译：皮肤取代膜，模具，制造皮肤取代膜的方法，以及用于外用于皮肤的评估剂的方法
公开(公告)号：JP2010107522A
公开(公告)日：2010-05-13
申请号：JP2010020665
申请日：2010-02-01
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： MIURA YOSHIMASA , MIZUNO HIROKO , HATAO MASATO , OGURI MOTOKI , HARA YUSUKE
IPC分类号： G01N21/33
CPC分类号： G01N33/5082
摘要： PROBLEM TO BE SOLVED: To provide a skin-substitutive membrane capable of precisely measuring transmittance characteristic and/or reflection characteristic of ultraviolet rays of an agent for external application onto the skin, a mold to be used for manufacturing the skin-substitutive membrane, method of manufacturing the skin-substitutive membrane, and the method of evaluating agent for external application onto the skin.
SOLUTION: The skin-substitutive membrane of polymethyl methacrylate, polyethylene, nylon or quartz is 0.2 to 5 mm in thickness, 50 to 100% in spectral transmittance of light having the wave length of 290 to 400 nm. On the surface of one side, groove-like recesses 2, the cross section of which are chamfered and flat surface parts 3 are formed, and arithmetic average roughness (Sa) is 10 to 50 μm. The width of the recessed parts 2 are 50 to 500 μm, and the depth of the same are 30 to 150 μm. The flat parts 3 are imparted with the chamfered roughness, and the arithmetic average roughness (Sa) is 0.1 to 30 μm.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：为了提供能够精确测量外用于皮肤的试剂的紫外线的透射特性和/或反射特性的皮肤替代膜，用于制造皮肤代用性的模具膜，皮肤代用膜的制造方法以及评价外用于皮肤的药剂的方法。解决方案：聚甲基丙烯酸甲酯，聚乙烯，尼龙或石英的皮肤替代膜的厚度为0.2至5mm，波长为290至400nm的光的光谱透射率为50至100％。在一侧的表面上，形成有截面为倒角的槽状凹部2，平面部3形成，算术平均粗糙度（Sa）为10〜50μm。凹部2的宽度为50〜500μm，深度为30〜150μm。平坦部3赋予倒角粗糙度，算术平均粗糙度（Sa）为0.1〜30μm。版权所有（C）2010，JPO＆INPIT

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