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1. 发明专利

JP2007151899A Horny layer cell discrimination method 审中-公开
标题翻译： HORNY层细胞鉴别方法
公开(公告)号：JP2007151899A
公开(公告)日：2007-06-21
申请号：JP2005352859
申请日：2005-12-07
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： FUJIWARA NORIO
IPC分类号： A61B5/00
摘要： PROBLEM TO BE SOLVED: To provide a technique for selectively dying a hydrophobic region of a horny layer cell and discriminating its hydrophobicity/hydrophilicity under an optical microscope.
SOLUTION: A horny layer cell discrimination method includes dying the horny layer cell taken from skin with a stain solution that contains 30-50% by mass of ethanol including Sudan Black B from a direction of a region contacting its surrounding and discriminating its hydrophobicity/hydrophilicity under the optical microscope.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种选择性地染色角质层细胞的疏水区域并在光学显微镜下鉴别其疏水性/亲水性的技术。解决方案：角质层细胞鉴别方法包括从含有30-50质量％的包含苏丹黑B的乙醇的污染溶液中，从与皮肤周围区域接触的区域的方向染色角质层细胞，并鉴别其光学显微镜下的疏水性/亲水性。版权所有（C）2007，JPO＆INPIT

2. 发明专利

JP2006017688A Differentiation method for subcorneal cell by autofluorescence 审中-公开
标题翻译：通过自动化分析细胞分化方法
公开(公告)号：JP2006017688A
公开(公告)日：2006-01-19
申请号：JP2004225024
申请日：2004-08-02
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： FUJIWARA NORIO
IPC分类号： G01N33/48 , G01N21/64 , G01N33/483 , G01N33/50
摘要： PROBLEM TO BE SOLVED: To provide a technique capable of finding an index for differentiating a subcorneal cell instead of a shape of the subcorneal cell, and capable of differentiating thereby a characteristic of a skin in a short time.
SOLUTION: In this method of differentiating the subcorneal cell collected from the skin, an ultraviolet ray is emitted from an ultraviolet ray source toward the subcorneal cell on a slide glass sealed with an immersion oil, under observation by a microscope or magnification video, and fluorescence intensity of the subcorneal cell excited by the ultraviolet ray is used as the index. The skin is differentiated based on a characteristic difference in stereoscopic structure of a keratin constituting the differentiated subcorneal cell.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种能够找到用于区分亚膜下细胞而不是亚下膜细胞的形状的指标的技术，并且能够在短时间内区分皮肤的特征。解决方案：在这种区分从皮肤收集的亚皮下细胞的方法中，通过用显微镜或放大视频观察，在用浸渍油密封的载玻片上从紫外线源向次角膜细胞发射紫外线使用紫外线激发的子宫内膜细胞的荧光强度作为指标。基于构成分化的下膜细胞的角蛋白的立体结构的特征差异来区分皮肤。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2005283596A Selecting method for make-up cosmetic 审中-公开
标题翻译：选择化妆品的方法
公开(公告)号：JP2005283596A
公开(公告)日：2005-10-13
申请号：JP2005135904
申请日：2005-05-09
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： MIYAZAWA MASAKAZU , FUJIWARA NORIO , KASHIBUCHI NOBUO , HIRAI YOSHIKAZU
IPC分类号： G01N33/15 , A61K8/00 , A61Q1/00 , A61Q1/02 , A61Q1/12
摘要： PROBLEM TO BE SOLVED: To provide a method of selecting easily and objectively a proper make-up cosmetic.
SOLUTION: The make-up cosmetic such as a foundation is selected, using an existence state of melanin and color irregularity in a skin, as indexes. A weight ratio relation between the existence state of melanin and the color irregularity is found using a regression expression obtained by multiple-regression-analyzing preliminarily an evaluation point A of digitalizing a difference in the existence state of melanin in a cuticle cell, an evaluation point B of digitalizing a difference in the color irregularity in a face, and beauty of the skin evaluated based on the evaluation point A, the evaluation point B, and an impression as the whole face, the evaluation point A and the evaluation point B are multiplied with the weight ratio to obtain an evaluation point C, and a make-up cosmetic is selected in response to a stage of the evaluation point C, according to the evaluation point C and a degree of covering power of the make-up cosmetics classified preliminarily into five stages.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种容易且客观地选择适当化妆品的方法。解决方案：使用黑色素的存在状态和皮肤中的颜色不规则性作为指标，选择诸如基础的化妆品化妆品。使用通过多次回归分析得到的回归表达式，求出黑色素的存在状态与颜色不规则性之间的重量比关系，所述回归表达式预先评价将角质层细胞中黑色素的存在状态的差异进行数字化的评价点A，评价点 B，根据评价点A，评价点B和作为整个面部的印象，评价点A和评价点B进行评价的皮肤的美观，将脸部的颜色不均匀的差异进行数字化以重量比获得评价点C，根据评价点C和初步分类的补充化妆品的覆盖力的程度，根据评价点C的阶段选择化妆品分为五个阶段版权所有（C）2006，JPO＆NCIPI

4. 发明专利

JP2005225894A Method for selecting makeup cosmetic 审中-公开
标题翻译：选择化妆品的方法
公开(公告)号：JP2005225894A
公开(公告)日：2005-08-25
申请号：JP2005135777
申请日：2005-05-09
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： MIYAZAWA MASAKAZU , KASHIBUCHI NOBUO , FUJIWARA NORIO , HIRAI YOSHIKAZU
IPC分类号： A61K8/00 , A61Q1/00 , A61Q1/02 , A61Q1/12 , A61Q90/00 , A61K7/00 , A61K7/02
摘要： PROBLEM TO BE SOLVED: To provide a means capable of easily selecting a suitable makeup cosmetic.
SOLUTION: The makeup cosmetics are selected by using an index based on existing states of melamine in keratinocyte of the skin. Thereby, the means capable of easily selecting the suitable makeup cosmetic is provided.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供能够容易地选择合适的化妆品的装置。
解决方案：通过使用基于皮肤角质形成细胞中三聚氰胺的现有状态的指数来选择化妆化妆品。因此，提供了能够容易地选择合适的化妆品的装置。版权所有（C）2005，JPO＆NCIPI

5. 发明专利

JP2006053117A Liquid for dyeing corneocyte and method for dyeing corneocyte using it 审中-公开
标题翻译：用于染色骨架的液体和使用它的染色体的方法
公开(公告)号：JP2006053117A
公开(公告)日：2006-02-23
申请号：JP2004266335
申请日：2004-09-14
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： YAMAZAKI KAZUHIRO , FUJIWARA NORIO
IPC分类号： G01N33/50 , G01N1/28 , G01N1/30 , G01N33/48
摘要： PROBLEM TO BE SOLVED: To provide a dyeing liquid and a dyeing method, capable of quickly dyeing corneocytes clearly and easily all over the place, and of being used for a skin corneocyte evaluating method in order to offer counselings and cosmetic selections with useful information.
SOLUTION: The dyeing liquid contains a dye, alcohol, and an organic acid. A tool for dyeing the corneocyte is provided, which is composed of a reservoir, a core section, and a lid section. The method for dyeing the corneocyte brings the corneocyte or a corneocyte specimen to be in contact with the dyeing liquid for a period of 10 or less seconds, and measures or determines an area value of the skin corneocyte, alignment regularity of the corneocytes, a shape of the corneocyte, a peel state of the corneocyte and the like. Furthermore, a method for discriminating skin states which employs a result of the above determination, is provided in order to select a makeup material.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了提供染色液体和染色方法，能够在整个地方清楚地和容易地染色角膜细胞，并且用于皮肤角质细胞评估方法，以便提供咨询和美容选择有用的信息。
解决方案：染色液体含有染料，醇和有机酸。提供了一种用于染色角膜细胞的工具，其由储存器，芯部分和盖部分组成。染色角膜细胞的方法使得角膜细胞或角质细胞样品与染色液体接触10秒或更少的时间，并测量或确定皮肤角质细胞的面积值，角膜细胞的取向规律，形状的角质细胞，剥离状态的角质细胞等。此外，为了选择化妆材料，提供了一种鉴别使用上述确定结果的皮肤状态的方法。版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2005270116A Identification method for barrier function of skin 审中-公开
标题翻译：皮肤障碍功能鉴定方法
公开(公告)号：JP2005270116A
公开(公告)日：2005-10-06
申请号：JP2005165474
申请日：2005-06-06
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： KASHIBUCHI NOBUO , FUJIWARA NORIO , HIRAI YOSHIKAZU
IPC分类号： G01N33/50 , C12Q1/02 , G01N33/15
摘要： PROBLEM TO BE SOLVED: To provide an identification method for horny layer barrier functions, simple and applicable to selection of cosmetics.
SOLUTION: The barrier functions of the skin is identified in observation of horny layer samples picked up from the epidermis by discriminating alignment regularity of the keratinocytes, existence of nucleated cells and the cell area and by using one or more selected from these items as the index.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供角质层屏障功能的识别方法，简单且适用于化妆品的选择。解决方案：通过区分角质形成细胞的比对规律，有核细胞的存在和细胞区域以及通过使用从这些物质中选出的一种或多种来观察从表皮拾取的角质层样品，鉴定皮肤的屏障功能作为指标。版权所有（C）2006，JPO＆NCIPI

7. 发明专利

JP2005348991A Skin discriminating method, method for selecting cosmetic by the discriminating method, and method for presenting cosmetic using the methods 有权
标题翻译：皮肤鉴别方法，通过鉴别方法选择化妆品的方法和使用该方法呈现化妆品的方法
公开(公告)号：JP2005348991A
公开(公告)日：2005-12-22
申请号：JP2004173629
申请日：2004-06-11
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： FUJIWARA NORIO , YOSHIHAMA KEIICHIRO
IPC分类号： G01N21/64 , A61B5/00 , A61B5/107
摘要： PROBLEM TO BE SOLVED: To provide a skin discriminating method for discriminating skin with the fluoroscopic intensity of horny layer cells as an index, a cosmetic selecting method based on the skin discriminating method, and a cosmetic presenting method using the methods.
SOLUTION: In the skin discriminating method, the horny layer cells collected from the skin are irradiated with UV rays, so as to estimate the existence rate of β-sheet type keratin in the horny layer cells and/or to discriminate skin flexibility through the use of the fluoroscopic intensity with light emission by the UV rays. The cosmetic suitable for the discriminated skin flexibility is selected and the magnified image of the horny layer cells, which is used for discrimination, is presented.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供用角质层细胞的荧光透视强度鉴别皮肤的皮肤鉴别方法作为指标，基于皮肤鉴别方法的化妆选择方法和使用该方法的化妆品呈现方法。解决方案：在皮肤鉴别方法中，从紫外线照射从皮肤收集的角质层细胞，以估计角质层细胞中β-片型角蛋白的存在率和/或鉴别皮肤柔韧性通过使用紫外线发射的荧光强度。选择适合于区分出的皮肤柔韧性的化妆品，并且呈现用于鉴别的角质层细胞的放大图像。版权所有（C）2006，JPO＆NCIPI

8. 发明专利

JP2005283595A Selecting method for cosmetic 审中-公开
标题翻译：选择化妆品的方法
公开(公告)号：JP2005283595A
公开(公告)日：2005-10-13
申请号：JP2005135785
申请日：2005-05-09
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： MIYAZAWA MASAKAZU , FUJIWARA NORIO , KASHIBUCHI NOBUO , HIRAI YOSHIKAZU
IPC分类号： G01N33/15 , A61K8/00 , A61K8/02 , A61Q19/00 , A61Q19/02 , A61K7/00 , A61K7/48
摘要： PROBLEM TO BE SOLVED: To provide a method of selecting easily and objectively a cosmetic such as a proper lightening cosmetic.
SOLUTION: The cosmetic such as the lightening cosmetic is selected using an existence state of melanin and color irregularity in a skin, as indexes. A weight ratio relation between the existence state of melanin and the color irregularity is found using a regression expression obtained by multiple-regression-analyzing preliminarily an evaluation point A of digitalizing a difference in the existence state of melanin in a collected cuticle cell, an evaluation point B of digitalizing a difference in the color irregularity in a face, and beauty of the skin evaluated based on the evaluation point A, the evaluation point B, and an impression as the whole face, the evaluation point A and the evaluation point B are multiplied with the weight ratio to obtain an evaluation point C (color tone favorableness), and a lightening foundation cosmetic is selected in response to a stage of the evaluation point C according to a degree of lightening action, as to the lightening foundation cosmetics classified preliminarily into five stages.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种方便地客观地选择化妆品如适当的减轻化妆品的方法。作为指标，使用黑色素的存在状态和皮肤中的颜色不规则性来选择化妆品，例如减轻化妆品。使用通过多次回归分析得到的回归表达式，求出黑色素的存在状态与颜色不规则性之间的重量比关系，该回归表达式初步评价了将收集的角质层细胞中黑色素的存在状态的差异进行数字化的评价点A，评价将基于评价点A，评价点B和作为整个面部的印象的评价的皮肤的美观度，评价点A和评价点B进行数字化，使脸部的颜色不均匀的差异数字化的点B 乘以重量比，得到评价点C（色调有利性），根据减轻作用程度的评价点C的阶段，对于初步分类的减轻性基础化妆品，选择发光粉底料分为五个阶段版权所有（C）2006，JPO＆NCIPI

9. 发明专利

JP2007263655A Skin judgement method by means of congo red 审中-公开
标题翻译：通过红色的皮肤判定方法
公开(公告)号：JP2007263655A
公开(公告)日：2007-10-11
申请号：JP2006087376
申请日：2006-03-28
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： FUJIWARA NORIO
IPC分类号： G01N33/50 , A61B5/00 , A61B5/107 , G01N1/04 , G01N1/28 , G01N1/30 , G01N33/48 , G01N33/483
摘要： PROBLEM TO BE SOLVED: To provide a technique for checking on β-sheet keratin in skin horny layer cells in order to perform more accurate skin judgement thereby estimating its existence rate with high quantitativeness.
SOLUTION: This is a skin judgement method. According to this judgement method for skin with respect to skin softness, etc., horny layer cells taken from the skin are dyed with Congo red (direct fast scarlet) and the β-sheet keratin in the dyed horny layer cells is observed under a polarizing microscope to estimate the existence rate of the keratin with high quantitativeness.
COPYRIGHT: (C)2008,JPO&INPIT

10. 发明专利

JP2003315331A Discrimination method of honey cell 有权
标题翻译：蜂窝细胞的鉴别方法
公开(公告)号：JP2003315331A
公开(公告)日：2003-11-06
申请号：JP2002120616
申请日：2002-04-23
申请人： Pola Chem Ind Inc , ポーラ化成工業株式会社
发明人： FUJIWARA NORIO , KASHIBUCHI NOBUO , YAMAZAKI KAZUHIRO , HIRAI YOSHIKAZU , HIRAYAMA MASAYA
IPC分类号： G01N33/50 , G06T1/00
摘要： PROBLEM TO BE SOLVED: To provide a means for precisely grasping the shape of a honey cell without a dyeing process.
SOLUTION: The honey cell collected from a skin by a pressure-sensitive adhesive tape or the like is imaged under an ultraviolet transmission condition or an ultraviolet reflection condition, and shape characteristics such as the area, the shape or the exfoliation pattern of the honey cell are discriminated from the image. The wavelength of the ultraviolet ray is preferably 340-380 nm for excitation, and the light source is preferably an L light source for excitation. Skin characteristics such as sensitivity of the skin to a stimulus, the skin state including barrier function, or a skin age showing the aging degree of the skin are discriminated based on the discrimination.
COPYRIGHT: (C)2004,JPO
摘要翻译：要解决的问题：提供一种在没有染色过程的情况下精确地掌握蜂窝电池的形状的手段。解决方案：通过压敏胶带等从皮肤收集的蜂窝细胞在紫外线透射条件或紫外线反射条件下成像，并且形状特征如面积，形状或剥离图案蜜蜂细胞与图像区分开来。对于激发，紫外线的波长优选为340〜380nm，光源优选为L激发用光源。基于鉴别判断皮肤特性如皮肤对刺激的敏感性，皮肤状态（包括屏障功能）或皮肤老化程度。版权所有（C）2004，JPO

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