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    • 1. 发明专利
    • Calcium phosphate bone filler and method for producing the same
    • 磷酸钙骨填料及其生产方法
    • JP2010075247A
    • 2010-04-08
    • JP2008244086
    • 2008-09-24
    • Osaka Sangyo Univ学校法人大阪産業大学
    • SAKAMOTO KIYOKOYAMAGUCHI TOSHIRO
    • A61L27/00
    • PROBLEM TO BE SOLVED: To provide a bone filler being sufficiently hardened, wherein a hardened material has a sufficient strength, and having a superior adhesion to bone cells. SOLUTION: The bone filler is formed by kneading phosphate-based mixture containing calcium monohydrogen phosphate (DCPD), tetracalciurn phosphate (TTCP) and abrasively pulverized β-tricalcium phosphate (β-TCP), with kneading solution containing water, wherein the β-TCP is abrasively pulverized under atmosphere containing at least one selected from water and carbon dioxide, and this bone filler contains 1.1-3 mol of the TTCP and 1.1-5 mol of the β-TCP with respect to 1 mol of the DCPD. COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:为了提供充分硬化的骨填料,其中硬化材料具有足够的强度,并且具有优于骨细胞的粘附性。 解决方案:通过将含有磷酸一氢钙(DCPD),磷酸四钙(TTCP)和研磨性粉碎的β-磷酸三钙(β-TCP))的磷酸盐基混合物与含水的捏合溶液捏合而形成骨填料,其中 在含有选自水和二氧化碳中的至少一种的气氛下,β-TCP被磨蚀性粉碎,该骨填料相对于1mol的DCPD,含有1.1-3mol的TTCP和1.1-5mol的β-TCP。 版权所有(C)2010,JPO&INPIT