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    • 1. 发明专利
    • Microscope system
    • 微观系统
    • JP2006139181A
    • 2006-06-01
    • JP2004330377
    • 2004-11-15
    • Olympus Corpオリンパス株式会社
    • TSUYUKI HIROSHI
    • G02B21/00
    • G02B7/08G02B21/242
    • PROBLEM TO BE SOLVED: To finely adjust a focusing position in a proper relative positional relation between a specimen and an objective lens by quickly moving the specimen and objective lens close to or apart from each other without paying attention to a positional relation between the specimen and the objective lens.
      SOLUTION: The microscope system 1 comprises: a first focus mechanism 8 for moving the objective lens 5 close to or apart from a specimen A along an optical axis direction; a second focus mechanism 25 for displacing an internal optical system 22 along the optical axis direction; and a switching device 34 for switching between an operation by the first focus mechanism 8 and an operation by the second focus mechanism 25 when the objective lens 5 is placed in a predetermined switching position.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:通过将样本和物镜快速移动到彼此靠近或分离的位置,不必注意位置关系之间的位置关系,可以在样本和物镜之间的适当的相对位置关系中微调聚焦位置 样品和物镜。 解决方案:显微镜系统1包括:第一聚焦机构8,用于沿着光轴方向移动物镜5靠近或远离样本A. 第二对焦机构25,用于沿着光轴方向移位内部光学系统22; 以及切换装置34,用于在将物镜5置于预定的切换位置时,​​在第一聚焦机构8的操作和第二对焦机构25的操作之间进行切换。 版权所有(C)2006,JPO&NCIPI
    • 2. 发明专利
    • Camera obscura device for fluorescence observation, fluorescence observation system, and fluorescence observation method
    • 用于荧光观察,荧光观察系统和荧光观察方法的相机用OBSCURA装置
    • JP2006071544A
    • 2006-03-16
    • JP2004257240
    • 2004-09-03
    • Olympus Corpオリンパス株式会社
    • TSUYUKI HIROSHICHO KAZUHIKONAGASAWA NOBUYUKI
    • G01N21/64G02B21/24
    • G01N21/6458G01N21/6456
    • PROBLEM TO BE SOLVED: To provide a clear fluorescent picture by removing noise in a fluorescent picture obtained in fluorescence observation while checking relative positional relation between a fluorescence observation device and a specimen even during fluorescence observation.
      SOLUTION: This camera obscura device 1 for fluorescence observation is equipped with: a camera obscura body 2 for covering the specimen A and the fluorescence observation device 5, the observation device 5 illuminating the specimen A with excitation light L1 of a first wavelength band to detect fluorescence L2 of a second wavelength band generated from the specimen A; an illumination light source 3 disposed in the obscura body 2 for outputting visible light L3 of a third wavelength band different from the first and second wavelength bands; and an observation window 4 provided in the obscura body 2 and transmitting light of a fourth wavelength band not including the first and second wavelength bands but including at least a part of the third wavelength band.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:即使在荧光观察期间,也可以在检测荧光观察装置与试样之间的相对位置关系的同时,通过去除在荧光观察中获得的荧光图像中的噪声来提供清晰的荧光图像。

      解决方案:该照相机遮光装置1用于荧光观察配备有:用于覆盖样本A和荧光观察装置5的照相机遮蔽体2,观察装置5用第一波长的激发光L1照射样本A 检测从样品A产生的第二波长带的荧光L2; 设置在遮光体2中用于输出不同于第一和第二波长带的第三波长带的可见光L3的照明光源3; 以及设置在遮光体2中并且透射不包括第一和第二波长带但包括第三波长带的至少一部分的第四波长带的光的观察窗4。 版权所有(C)2006,JPO&NCIPI

    • 3. 发明专利
    • Living body observing apparatus
    • 生活观察装置
    • JP2007316409A
    • 2007-12-06
    • JP2006146633
    • 2006-05-26
    • Olympus Corpオリンパス株式会社
    • SHIODA KIMIINAGASAWA NOBUYUKITSUYUKI HIROSHI
    • G02B7/28G02B21/00G03B15/02
    • PROBLEM TO BE SOLVED: To provide a living body observing apparatus capable of quickly and accurately performing focusing on a sample having a height such as a living body. SOLUTION: The living body observing apparatus is equipped with: an optical system 7 including an objective lens 6 for observing the sample 4; a focus moving mechanism 9 for adjusting the relative position of the objective lens 6 and the sample 4 along the direction of the optical axis 10 of the optical system 7; and a plurality of illuminating parts 2 for emitting spot light 3. The illuminating parts 2 are arranged so that the spot light beams 3 emitted from the parts 2 cross each other on the focal plane of the objective lens 6. COPYRIGHT: (C)2008,JPO&INPIT
    • 解决的问题:提供一种能够快速且准确地对具有诸如生物体的高度的样品进行聚焦的生物体观测装置。 生物体观察装置配备有:包括用于观察样品4的物镜6的光学系统7; 用于调整物镜6和样本4沿着光学系统7的光轴10的方向的相对位置的聚焦移动机构9; 以及用于发射点光3的多个照明部分2.照明部分2被布置成使得从部件2发射的光束3在物镜6的焦平面上彼此交叉。版权所有( C)2008,JPO&INPIT
    • 4. 发明专利
    • Scanning laser microscope
    • 扫描激光显微镜
    • JP2006003394A
    • 2006-01-05
    • JP2004176776
    • 2004-06-15
    • Olympus Corpオリンパス株式会社
    • TSUYUKI HIROSHI
    • G02B21/00G02B26/10
    • PROBLEM TO BE SOLVED: To provide a scanning laser microscope attaining the synchronization of the scanning position of a 1st scanning optical system and the scanning position of a 2nd scanning optical system.
      SOLUTION: The scanning laser microscope is provided with the 1st scanning optical system A for irradiating and scanning a sample 118 with light, the 2nd scanning optical system B for irradiating and scanning the sample 118 with light, a detecting optical system C for detecting the light generated from the sample 118 through a part of the 1st scanning optical system A, and a control unit 120 for driving the 1st scanning optical system A and the 2nd scanning optical system B, so as to scan in synchronism with each other.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:提供一种使第一扫描光学系统的扫描位置与第二扫描光学系统的扫描位置同步的扫描激光显微镜。 解决方案:扫描激光显微镜配备有用于用光照射和扫描样品118的第一扫描光学系统A,用于用光照射和扫描样品118的第二扫描光学系统B,用于对样品118进行光扫描的检测光学系统C 通过第一扫描光学系统A的一部分检测从样品118产生的光,以及用于驱动第一扫描光学系统A和第二扫描光学系统B的控制单元120,以便彼此同步扫描。 版权所有(C)2006,JPO&NCIPI
    • 5. 发明专利
    • 顕微鏡システム
    • 微观系统
    • JP2014232286A
    • 2014-12-11
    • JP2013114328
    • 2013-05-30
    • オリンパス株式会社Olympus Corp
    • TSUYUKI HIROSHI
    • G02B21/06G02B21/36
    • 【課題】所望のタイミング以外のタイミングで標本にレーザ光が照射されてしまうのを抑制し、標本への光の照射のON/OFFを任意のタイミングで切り替える。【解決手段】刺激光を発生する刺激光源5と、刺激光を標本Sに照射する刺激光学系6と、刺激光に対して刺激光学系6に入射する角度に回折するON状態と入射しない角度に回折するOFF状態とに切り替え可能な第2音響光学素子41と、刺激光源5と刺激光学系6との間の光路に挿脱可能に設けられ、光路を開放する開状態と閉鎖する閉状態とに切り替え可能な第2メカニカルシャッタ43と、これらの第2音響光学素子41および第2メカニカルシャッタ43により標本Sへの刺激光の照射のON/OFFを制御するCPUとを備え、CPUが、第2音響光学素子41をON状態に切り替える前に第2メカニカルシャッタ43を開状態に切り替える顕微鏡システム100を提供する。【選択図】図1
    • 要解决的问题:防止样品在期望时间以外的时刻被激光照射,并且在任何时刻用光照射样品的ON / OFF。解决方案:提供显微镜系统100 其包括:产生刺激光的刺激光源5; 刺激光学系统6,用刺激光照射样本S; 第二声光学元件41可以在以与入射到刺激光学系统6的角度相对于激励光的衍射的ON状态之间切换,并且在相对于刺激光的衍射相对于激发光的衍射处于OFF状态 未事件发生的角度; 第二机械快门43,其可插入地和可缩回地设置在激励光源5和刺激光学系统6之间的光路中,并且可在导致光路打开的打开状态和导致光路到达的闭合状态之间切换 关闭 以及CPU,其通过第二声光学元件41和第二机械快门43来控制用刺激光照射样本S的ON / OFF .CPU在切换第二机械快门43之前将第二机械快门43切换到打开状态 声光元件41变为ON状态。
    • 8. 发明专利
    • Confocal observation system, photoirradiation method and photoirradiation program
    • 协同观测系统,光照方法和光照方案
    • JP2006003805A
    • 2006-01-05
    • JP2004182552
    • 2004-06-21
    • Olympus Corpオリンパス株式会社
    • TSUYUKI HIROSHINAKADA TATSUO
    • G02B21/00G01B11/24
    • PROBLEM TO BE SOLVED: To accurately perform luminous stimulus and photobleach in the corresponding area of a sample by specifying an optional three-dimensional area in a stereoscopic sample image, and to accurately perform the analysis of the behavior of the sample having a stereostructure after the luminous stimulus is performed.
      SOLUTION: The confocal laser microscope as the confocal observation system is provided with a scanning optical system A and a detection optical system B for obtaining the optical cross section image of the stereoscopic sample 9, and a control unit 14 or the like for performing processing of forming the three-dimensional image from the obtained optical cross section image, processing of specifying a desired three-dimensional area in the formed three-dimensional image, processing of obtaining a cross section area to be irradiated with exciting light or stimulating light based on the specified three-dimensional area and processing of irradiating the area of the stereoscopic sample 9 corresponding to the obtained cross section area with the exciting light or the stimulating light.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:通过在立体样本图像中指定可选的三维区域来准确地执行样品的相应区域中的发光刺激和光漂白,并且准确地执行具有 执行发光刺激后的立体结构。 解决方案:作为共聚焦观察系统的共聚焦激光显微镜设置有用于获得立体样本9的光学截面图像的扫描光学系统A和检测光学系统B,以及控制单元14等 从所获得的光学截面图像执行形成三维图像的处理,在形成的三维图像中指定期望的三维区域的处理,获得要用激发光照射的横截面积或刺激光的处理 基于指定的三维区域,以及利用激发光或刺激光照射对应于所获得的截面区域的立体样本9的区域的处理。 版权所有(C)2006,JPO&NCIPI