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1. 发明专利

JP2009207493A Method for producing biosurfactant using fermentation product of plant as medium 审中-公开
标题翻译：使用植物发酵产物生产生物活性剂的方法
公开(公告)号：JP2009207493A
公开(公告)日：2009-09-17
申请号：JP2009026973
申请日：2009-02-09
申请人： National Institute Of Advanced Industrial & Technology , Sanwa Shurui Co Ltd , 三和酒類株式会社 , 独立行政法人産業技術総合研究所
发明人： OMORI TOSHIRO , TAKESHIMA NAOKI , HAYASHI KEI , MARUOKA IKUYUKI , KONISHI MASAO , FUKUOKA TOKUMA , MORITA TOMOTAKE , IMURA TOMOHIRO , KITAMOTO MASARU
IPC分类号： C12P19/00
摘要： PROBLEM TO BE SOLVED: To provide a method for efficiently producing a highly functional microbial surface active substance (biosurfactant) by efficiently making use of compositions being byproducts in the processes of producing the liquors, excluding liquors, as unused resource.
SOLUTION: The biosurfactant is produced by fermentation at lower cost in a shorter period of time and more efficiently by using a medium containing a composition excluding liquor which is a byproduct in the process of producing the liquor, compared with a process using a conventional production medium, and in addition, the compositions excluding liquors which have been the unused resource of the byproducts in the process of producing the liquor is effectively used.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种通过在生产不含酒的液体的过程中有效地利用作为副产物的组合物来有效地生产高功能微生物表面活性物质（生物表面活性剂）的方法作为未使用的资源。解决方案：生物表面活性剂通过在较短的时间内以更低的成本发酵，并且通过使用含有不含作为生产液体中副产物的液体的组合物的培养基，与使用常规的生产介质，另外，在生产液体的过程中，除了已经是副产物的未使用资源的液体组合物被有效地使用。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2010158192A Microorganism having ability of producing saccharide type biosurfactant and method for producing saccharide type biosurfactant using the same 有权
标题翻译：具有生产SACCHARIDE型生物交换剂的能力的微生物和使用其生产SACCHARIDE型生物交换剂的方法
公开(公告)号：JP2010158192A
公开(公告)日：2010-07-22
申请号：JP2009001914
申请日：2009-01-07
申请人： National Institute Of Advanced Industrial Science & Technology , Sanwa Shurui Co Ltd , 三和酒類株式会社 , 独立行政法人産業技術総合研究所
发明人： OMORI TOSHIRO , MARUOKA IKUYUKI , FURUTA YOSHIFUMI , KONISHI MASAO , FUKUOKA TOKUMA , MORITA TOMOTAKE , IMURA TOMOHIRO , KITAMOTO MASARU
IPC分类号： C12N1/14 , A23K1/16 , A23L1/30 , A61K8/60 , C12P19/04
摘要： PROBLEM TO BE SOLVED: To provide a microorganism having ability of producing a biosurfactant isolated from an edible plant so as to provide a biosurfactant having more excellent adaptability than that of the conventional one for uses more requiring safety to living organisms in cosmetics, foods, agricultural and stock raising industries and a method for producing a biosurfactant using the microorganism.
SOLUTION: The microorganism belongs to the genus Ustilago having ability of producing a biosurfactant without producing a mannosylerythritol lipid. The method for producing a biosurfactant includes culturing the microorganism and producing the biosurfactant.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种具有从食用植物分离的生物表面活性剂的生产能力的微生物，以提供具有比常规的生物表面活性剂更好的适用性的生物表面活性剂，其用于对化妆品中生物体的安全性更高，食品，农业和畜牧业以及使用微生物生产生物表面活性剂的方法。解决方案：微生物属于具有生产生物表面活性剂而不产生甘露糖酯类脂质的能力的乌斯特里亚属。制备生物表面活性剂的方法包括培养微生物并生产生物表面活性剂。版权所有（C）2010，JPO＆INPIT

3. 发明专利

JP2009126820A New mannosyl erythritol lipid and method for producing the same 有权
标题翻译：新型曼尼罗糖脂及其生产方法
公开(公告)号：JP2009126820A
公开(公告)日：2009-06-11
申请号：JP2007303164
申请日：2007-11-22
申请人： National Institute Of Advanced Industrial & Technology , Toyobo Co Ltd , 東洋紡績株式会社 , 独立行政法人産業技術総合研究所
发明人： YAMAMOTO SHUHEI , KITAGAWA MASARU , SOGABE ATSUSHI , FUKUOKA TOKUMA , IMURA TOMOHIRO , MORITA TOMOTAKE , KITAMOTO MASARU
IPC分类号： C07H13/06 , A61K8/60 , A61K31/7032 , A61P35/00 , C07H1/00 , C12P19/46 , C12R1/645
摘要： PROBLEM TO BE SOLVED: To provide a mannosyl erythritol lipid which has high degradability, low toxicity, and improved water solubility, and to provide a method for producing the mannosyl erythritol lipid. SOLUTION: This method for producing the new mannosyl erythritol lipid having at least one hydroxy group in a side chain fatty acid in the molecular structure comprises culturing a microorganism having an ability to produce the mannosyl erythritol lipid in a culture medium containing at least one hydroxy group-having fatty acid, its derivative or a vegetable oil. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供具有高降解性，低毒性和改善的水溶性的甘露糖基赤藓糖醇脂质，以及提供甘露糖基赤藓糖醇脂质的制备方法。解决方案：在分子结构中，在侧链脂肪酸中具有至少一个羟基的新的甘露糖基赤藓糖醇脂质的制造方法包括在至少含有甘露糖基赤藓糖醇脂肪酸的培养基中培养具有产生甘露糖基赤藓糖醇脂质的能力的微生物一个含羟基的脂肪酸，其衍生物或植物油。版权所有（C）2009，JPO＆INPIT

4. 发明专利

JP2008247845A Method for producing acid-type sophorose lipid 审中-公开
标题翻译：制备酸型脂肪酸脂的方法
公开(公告)号：JP2008247845A
公开(公告)日：2008-10-16
申请号：JP2007092936
申请日：2007-03-30
申请人： Lion Corp , National Institute Of Advanced Industrial & Technology , ライオン株式会社 , 独立行政法人産業技術総合研究所
发明人： KONISHI MASAO , FUKUOKA TOKUMA , MORITA TOMOTAKE , IMURA TOMOHIRO , KITAMOTO MASARU , IWABUCHI HIROYUKI
IPC分类号： C07H15/04 , C11D1/06 , C12N15/09 , C12P19/12
摘要： PROBLEM TO BE SOLVED: To provide a fermentation production method by which only a chemically stable acid-type sophorose lipid can selectively be produced by one step, in stead of a conventional sophorose lipid fermentation method by which the sophorose lipid is obtained as a mixture of a lactone type and the acid type.
SOLUTION: The method for producing the acid-type sophorose lipid includes subjecting Candida floricola of a microorganism selectively producing the acid-type sophorose lipid to liquid culture, and collecting the acid-type sophorose lipid.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：为了提供一种发酵生产方法，其仅通过一步可以选择性地产生化学稳定的酸型槐糖脂质，而不是通过其获得槐糖脂质的常规槐糖脂质发酵方法为内酯型和酸型的混合物。解决方案：制备酸型槐糖脂的方法包括将选择性生产酸型槐糖脂的微生物的花蕊花苜蓿植物进行液体培养，并收集酸型槐糖脂。版权所有（C）2009，JPO＆INPIT

5. 发明专利

JP2005087890A Method and apparatus for concentrating fermented alcohol aqueous solution 有权
标题翻译：用于浓缩发泡酒精水溶液的方法和装置
公开(公告)号：JP2005087890A
公开(公告)日：2005-04-07
申请号：JP2003325278
申请日：2003-09-17
申请人： National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所
发明人： IKEGAMI TORU , YAGISHITA HIROSHI , KITAMOTO MASARU , NEGISHI HIDEYUKI , IMURA TOMOHIRO
IPC分类号： C12G3/10 , B01D53/22 , B01D61/14 , B01D61/36 , B01D69/04 , B01D69/12 , B01D71/02 , B01D71/70
CPC分类号： B01D61/362 , B01D69/12 , B01D71/028 , C12P7/06
摘要： PROBLEM TO BE SOLVED: To provide a polyfunctional multilayer structure type separation membrane for stably producing a concentrated alcohol liquid from a dilute alcohol fermented liquid at the normal temperature using an alcohol selective separation membrane, and an alcohol manufacturing method using the separation membrane.
SOLUTION: The polyfunctional multilayer structure type separation membrane is constituted so that a porous membrane having a precise filtration function is arranged outside the alcohol permselective gas separation membrane coming into direct contact with a fermented liquid and a membrane for preventing that an organic acid is brought into contact with the alcohol permselective gas separation membrane (or adsorbed by the alcohol permselective gas separation membrane) is arranged between the precise filter membrane and the alcohol permselective gas separation membrane. The concentrated alcohol liquid is stably produced by this separation membrane.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种多官能多层结构型分离膜，用于使用醇选择性分离膜在常温下从稀醇发酵液稳定地生产浓缩醇液，以及使用该分离膜的醇制造方法。解决方案：多功能多层结构型分离膜构成为具有精确过滤功能的多孔膜布置在与发酵液直接接触的醇选择性气体分离膜的外部，并且用于防止有机酸与精选过滤膜和醇选择性气体分离膜之间布置有与醇选择性气体分离膜（或被醇选择性气体分离膜吸附）接触。通过该分离膜稳定地生产浓缩的醇液。版权所有（C）2005，JPO＆NCIPI

6. 发明专利

JP2009062288A Percutaneous absorption controller containing sophorolipid and method for producing the same 有权
标题翻译：含有异辛酸的非常吸收式控制剂及其制造方法
公开(公告)号：JP2009062288A
公开(公告)日：2009-03-26
申请号：JP2007229294
申请日：2007-09-04
申请人： National Institute Of Advanced Industrial & Technology , Saraya Kk , サラヤ株式会社 , 独立行政法人産業技術総合研究所
发明人： IMURA TOMOHIRO , HIRATA YOSHIHIKO , IGARASHI KEISUKE , RYU MIZUYUKI , ICHIYANAGI NAOKI
IPC分类号： A61K8/73 , A61K8/04 , A61K8/60 , A61K8/64 , A61K8/67 , A61K9/133 , A61K45/00 , A61K47/36 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a percutaneous absorption controller that includes a surfactant being a single component and having excellent biodegradability and no toxicity, is easily prepared without application of mechanical external force of strength and is thermodynamically stable.
SOLUTION: The percutaneous absorption controller includes a molecular assembly containing sophorolipid. The molecular assembly is a vesicle or a huge micelle and has its diameter of 40-200 nm. The molecular assembly contains at least any active ingredient of an antioxidant, an antimicrobial agent, an anti-inflammatory agent, a blood circulation promoter, a skin lightening ingredient, a rough skin inhibitor, an anti-aging agent, a hair growth promoter, a humectant, a hormone agent, a pigment, a glycoside, a protein, a lipid and a vitamin. When the percutaneous absorption controller is applied to the skin, the molecular assembly is permeated into gaps between corneocytes, lamella liquid crystal composed of intercellular lipid is melted and the components in the molecular assembly are diffused into the lamella liquid crystal.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：为了提供包含单一成分的表面活性剂并且具有优异的生物降解性和无毒性的经皮吸收控制剂，在不施加机械外力强度的情况下容易制备，并且是热力学稳定的。解决方案：经皮吸收控制器包括含有槐糖脂的分子组合物。分子组装是囊泡或巨大的胶束，其直径为40-200nm。分子组装体含有抗氧化剂，抗微生物剂，抗炎剂，血液循环促进剂，皮肤发光成分，粗糙皮肤抑制剂，抗老化剂，毛发生长促进剂，保湿剂，激素剂，颜料，糖苷，蛋白质，脂质和维生素。当将经皮吸收控制器应用于皮肤时，分子组装被渗透到角质细胞之间的间隙中，由细胞间脂质组成的薄片液晶熔化，分子组装中的组分扩散到薄片液晶中。版权所有（C）2009，JPO＆INPIT

7. 发明专利

JP2009035529A New mannosyl erythritol and method for producing the same 有权
标题翻译：新型人造丝菊酯及其生产方法
公开(公告)号：JP2009035529A
公开(公告)日：2009-02-19
申请号：JP2008117873
申请日：2008-04-28
申请人： National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所
发明人： FUKUOKA TOKUMA , MORITA TOMOTAKE , IMURA TOMOHIRO , KITAMOTO MASARU
IPC分类号： C07H15/04 , C12P19/44
摘要： PROBLEM TO BE SOLVED: To provide a new mannosyl erythritol as the hydrolyzate of MEL (mannosyl erythritol lipid) having 1-O-β-D-mannopyranosyl-meso-erythritol structure as an optical isomer of conventional MEL having 4-O-β-D-mannopyranosyl-meso-erythritol structure, and to provide a method for producing the same. SOLUTION: The new mannosyl erythritol is obtained by hydrolyzing MEL having 1-O-β-D-mannopyranosyl-meso-erythritol structure entirely different in chirality from conventional MEL, with erythritol reversely ether-linked to mannose. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供新的甘露糖基赤藓糖醇作为具有1-O-β-D-吡喃甘露糖基 - 内消旋 - 赤藓糖醇结构的MEL（甘露糖基赤藓糖醇脂质）的水解产物作为具有4-O的常规MEL的旋光异构体 -β-D-吡喃甘露糖基 - 内消旋 - 赤藓糖醇结构，并提供其制备方法。解决方案：新的甘露糖基赤藓糖醇通过水解具有与常规MEL完全不同手性的1-O-β-D-吡喃甘露糖基 - 内消旋赤藓糖醇结构的MEL与与甘露糖反相醚连接的赤藓糖醇获得。版权所有（C）2009，JPO＆INPIT

8. 发明专利

JP2009034090A Mannosyl erythritol lipid and method for producing the same 有权
标题翻译：花青素脂质体及其制备方法
公开(公告)号：JP2009034090A
公开(公告)日：2009-02-19
申请号：JP2008003615
申请日：2008-01-10
申请人： National Institute Of Advanced Industrial & Technology , Toyobo Co Ltd , 東洋紡績株式会社 , 独立行政法人産業技術総合研究所
发明人： KITAGAWA MASARU , SOGABE ATSUSHI , FUKUOKA TOKUMA , MORITA TOMOTAKE , IMURA TOMOHIRO , KITAMOTO MASARU
IPC分类号： C12P19/44 , C07H15/04 , C12R1/645
摘要： PROBLEM TO BE SOLVED: To provide a mannosyl erythritol lipid (MEL) having a 1-O-β-D-mannopyranosyl-meso-erythritol structure which is an optical isomer of a conventional MEL having a 4-O-β-D-mannopyranosyl-meso-erythritol structure and to provide a method for producing the MEL.
SOLUTION: A microorganism belonging to the genus Pseudozyma and having ability producing a mannopyronosyl erythritol lipid is cultured to produce the mannosyl erythritol lipid having the 1-O-β-D-mannopyranosyl-meso-erythritol structure.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：提供具有1-O-β-D-吡喃甘露糖基 - 内消旋 - 赤藓糖醇结构的甘露糖基赤藓糖醇脂质（MEL），其为具有4-O-β- D-甘露吡喃糖基 - 内消旋 - 赤藓糖醇结构，并提供一种生产MEL的方法。培养具有1-O-β-D-吡喃甘露糖基 - 内消旋赤藓糖醇结构的甘露糖基赤藓糖醇脂质的具有产生甘露聚糖苷类赤藓糖醇脂质的能力的微生物属于假酶属的微生物。版权所有（C）2009，JPO＆INPIT

9. 发明专利

JP2007037448A Method for reducing bitter taste of high-functional health food, and reduced bitter composition 有权
标题翻译：降低高功能健康食物的叮咬成分的方法和减少铋组合物
公开(公告)号：JP2007037448A
公开(公告)日：2007-02-15
申请号：JP2005224863
申请日：2005-08-03
申请人： Kanehide Bio Kk , National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所 , 金秀バイオ株式会社
发明人： TAKAHASHI MAKOTO , SADOYAMA KEIICHI , MIYAGI TAKESHI , KITAMOTO MASARU , IMURA TOMOHIRO
IPC分类号： A23L1/015 , A23L1/30
摘要： PROBLEM TO BE SOLVED: To provide a method for reducing bitter taste of high-functional health food by which bitter taste of turmeric extract, basidiomycetes extract or the like can be reduced easily, safely and relatively inexpensively. SOLUTION: The method for reducing bitter taste of high-functional health food comprises the following process: admixing nature-originated phospholipid comprising neutral phospholipid as a main active ingredient to high-functional health food containing bitter taste; and mechanically dispersing the obtained mixture. The bitter taste-containing substance may be at least one kind selected from turmeric extract or basidiomycetes extract. COPYRIGHT: (C)2007,JPO&INPIT

10. 发明专利

JP2006028069A Method for producing liposome utilizing coacervate 有权
标题翻译：生产使用油脂的脂质体的方法
公开(公告)号：JP2006028069A
公开(公告)日：2006-02-02
申请号：JP2004207860
申请日：2004-07-14
申请人： National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所
发明人： IMURA TOMOHIRO , KITAMOTO MASARU , YAGISHITA HIROSHI , NEGISHI HIDEYUKI , IKEGAMI TORU
IPC分类号： A61K9/127 , A61K47/36 , A61K47/44
摘要： PROBLEM TO BE SOLVED: To provide a method for producing liposome enabling substances including medicament, physiologically active substance and gene to be efficiently encapsulated, transferable into a target cell in high efficiency, and stable for a long time in the form of an aqueous solution. SOLUTION: The method for producing liposome comprises preparing it from coacervate formed by a glycolipid-based biosurfactant. The liposome thus produced is provided. A carrier comprising the liposome and to be used for transferring a medicament, physiologically active substance or gene into a biological body or cell is also provided. COPYRIGHT: (C)2006,JPO&NCIPI

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