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    • 8. 发明专利
    • Apoptosis-inducing substance contained in carotenoid-containing potato, potato raw material and processed article
    • 含有卡培他酮,POTATO原料和加工品的APOPTOSIS诱导物质
    • JP2006169125A
    • 2006-06-29
    • JP2004359864
    • 2004-12-13
    • Hiroshige HimawariNational Agriculture & Food Research OrganizationWada Sugar Refining Co Ltd和田製糖株式会社博重 樋▲廻▼独立行政法人農業・食品産業技術総合研究機構
    • HIMAWARI HIROSHIGEMORI MOTOYUKIKOBAYASHI AKIRATAKADA AKIKOTSUDA SHOGOENDO CHIETAKIGAWA SHIGENOBUHAYASHI KAZUYA
    • A61K31/047A23L1/216A23L1/30A61K36/81A61P35/00A61P43/00
    • PROBLEM TO BE SOLVED: To provide an apoptosis-inducing substance which contains a carotenoid pigment-containing extract originated from carotenoid-containing potato as an active ingredient, has greatly high safety, is more inexpensive than conventional anticancer agents, does not produce side effects, and can continuously be taken. SOLUTION: This apoptosis-inducing substance comprises a carotenoid pigment-containing extract extracted from a potato kind which is an ancestral potato kind for ordinary culture potato kinds, such as Solanum tuberosum ssp. tuberosam L. or Solanum phureja Juz. et Buk, a different culture potato kind, or a mated breeding kind based on them, improved in agronomic characters such as pigment concentration, disease resistance, yield or the like, and containing a carotenoid pigment in the flesh portion, has a yellow color tone of raw potato flesh portion in comparison with the Solanum tuberosum ssp. tuberosam L., and contains a carotenoid-based yellow pigment: zeaxanthin which is a main ingredient for forming the color tone of the flesh portion of the potato, in a concentration of ≥3 μg/g and has b * of ≥30 in L * , a * and b * color system and measured by a colorimeter, as a main ingredient for forming the color tone of the flesh portion. COPYRIGHT: (C)2006,JPO&NCIPI
    • 待解决的问题:为了提供含有含有类胡萝卜素的马铃薯作为活性成分的含有类胡萝卜素颜料的提取物的细胞凋亡诱导物质,具有极高的安全性,比常规抗癌剂更廉价,不产生 副作用,可以不断采取。 解毒剂:该细胞凋亡诱导物质包含从马铃薯种类提取的含有类胡萝卜素色素的提取物,其为普通培养马铃薯种类的祖传马铃薯,例如马铃薯(Solanum tuberosum ssp) tuberosam L.或Solanum phureja Juz。 et Buk,不同的培养土豆种类或基于它们的配种育种,改善了诸如颜料浓度,抗病性,产量等的农艺性状,并且在肉份中含有类胡萝卜素颜料,具有黄色调 的马铃薯生肉部分与马铃薯(Solanum tuberosum ssp)相比较。 并且含有以类胡萝卜素为基的黄色颜料:作为形成马铃薯肉质部分的色调的主要成分的玉米黄质,浓度≥3μg/ g,并且具有b SP> * ,SP> * 和b * 颜色系统中的SP>≥30,并通过比色计测量,作为形成 肉色的色调。 版权所有(C)2006,JPO&NCIPI